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Biomarkers of Micronutrients in Regular Follow-Up for Tyrosinemia Type 1 and Phenylketonuria Patients.

van Vliet K, Rodenburg IL, van Ginkel WG, Lubout CMA, Wolffenbuttel BHR, van der Klauw MM, Heiner-Fokkema MR, van Spronsen FJ.

Nutrients. 2019 Aug 27;11(9). pii: E2011. doi: 10.3390/nu11092011.


Prevalence of hypoglycaemia in a random population after Roux-en-Y gastric bypass after a meal test.

Emous M, van den Broek M, Wijma R, de Heide LJM, Laskewitz A, van Dijk G, Totté E, Wolffenbuttel BHR, van Beek AP.

Endocr Connect. 2019 Jun 1. pii: EC-19-0268. doi: 10.1530/EC-19-0268. [Epub ahead of print]


The Many Faces of Cobalamin (Vitamin B12) Deficiency.

Wolffenbuttel BHR, Wouters HJCM, Heiner-Fokkema MR, van der Klauw MM.

Mayo Clin Proc Innov Qual Outcomes. 2019 May 27;3(2):200-214. doi: 10.1016/j.mayocpiqo.2019.03.002. eCollection 2019 Jun. Review.


Development and Interlaboratory Validation of Two Fast UPLC-MS-MS Methods Determining Urinary Bisphenols, Parabens and Phthalates.

van der Meer TP, van Faassen M, Frederiksen H, van Beek AP, Wolffenbuttel BHR, Kema IP, van Vliet-Ostaptchouk JV.

J Anal Toxicol. 2019 Jul 24;43(6):452-464. doi: 10.1093/jat/bkz027.


Eye movement disorders and neurological symptoms in late-onset inborn errors of metabolism.

Koens LH, Tijssen MAJ, Lange F, Wolffenbuttel BHR, Rufa A, Zee DS, de Koning TJ.

Mov Disord. 2018 Dec;33(12):1844-1856. doi: 10.1002/mds.27484. Epub 2018 Nov 28. Review.


Skin autofluorescence predicts incident type 2 diabetes, cardiovascular disease and mortality in the general population.

van Waateringe RP, Fokkens BT, Slagter SN, van der Klauw MM, van Vliet-Ostaptchouk JV, Graaff R, Paterson AD, Smit AJ, Lutgers HL, Wolffenbuttel BHR.

Diabetologia. 2019 Feb;62(2):269-280. doi: 10.1007/s00125-018-4769-x. Epub 2018 Nov 21.


Active smoking and macrocytosis in the general population: Two population-based cohort studies.

Eisenga MF, Wouters HJCM, Kieneker LM, van der Klauw MM, van der Meer P, Wolffenbuttel BHR, Gaillard CAJM, Kootstra-Ros JE, Touw DJ, Huls G, Bakker SJL.

Am J Hematol. 2019 Feb;94(2):E45-E48. doi: 10.1002/ajh.25346. Epub 2018 Nov 27. No abstract available.


Postoperative use of somatostatin analogs and mortality in patients with acromegaly.

Postma MR, Wolters TLC, van den Berg G, van Herwaarden AE, Muller Kobold AC, Sluiter WJ, Wagenmakers MA, van den Bergh ACM, Wolffenbuttel BHR, Hermus ARMM, Netea-Maier RT, van Beek AP.

Eur J Endocrinol. 2019 Jan 1;180(1):1-9. doi: 10.1530/EJE-18-0166.


Genome-wide analyses identify a role for SLC17A4 and AADAT in thyroid hormone regulation.

Teumer A, Chaker L, Groeneweg S, Li Y, Di Munno C, Barbieri C, Schultheiss UT, Traglia M, Ahluwalia TS, Akiyama M, Appel EVR, Arking DE, Arnold A, Astrup A, Beekman M, Beilby JP, Bekaert S, Boerwinkle E, Brown SJ, De Buyzere M, Campbell PJ, Ceresini G, Cerqueira C, Cucca F, Deary IJ, Deelen J, Eckardt KU, Ekici AB, Eriksson JG, Ferrrucci L, Fiers T, Fiorillo E, Ford I, Fox CS, Fuchsberger C, Galesloot TE, Gieger C, Gögele M, De Grandi A, Grarup N, Greiser KH, Haljas K, Hansen T, Harris SE, van Heemst D, den Heijer M, Hicks AA, den Hollander W, Homuth G, Hui J, Ikram MA, Ittermann T, Jensen RA, Jing J, Jukema JW, Kajantie E, Kamatani Y, Kasbohm E, Kaufman JM, Kiemeney LA, Kloppenburg M, Kronenberg F, Kubo M, Lahti J, Lapauw B, Li S, Liewald DCM; Lifelines Cohort Study, Lim EM, Linneberg A, Marina M, Mascalzoni D, Matsuda K, Medenwald D, Meisinger C, Meulenbelt I, De Meyer T, Meyer Zu Schwabedissen HE, Mikolajczyk R, Moed M, Netea-Maier RT, Nolte IM, Okada Y, Pala M, Pattaro C, Pedersen O, Petersmann A, Porcu E, Postmus I, Pramstaller PP, Psaty BM, Ramos YFM, Rawal R, Redmond P, Richards JB, Rietzschel ER, Rivadeneira F, Roef G, Rotter JI, Sala CF, Schlessinger D, Selvin E, Slagboom PE, Soranzo N, Sørensen TIA, Spector TD, Starr JM, Stott DJ, Taes Y, Taliun D, Tanaka T, Thuesen B, Tiller D, Toniolo D, Uitterlinden AG, Visser WE, Walsh JP, Wilson SG, Wolffenbuttel BHR, Yang Q, Zheng HF, Cappola A, Peeters RP, Naitza S, Völzke H, Sanna S, Köttgen A, Visser TJ, Medici M.

Nat Commun. 2018 Oct 26;9(1):4455. doi: 10.1038/s41467-018-06356-1.


Association of anemia with health-related quality of life and survival: a large population-based cohort study.

Wouters HJCM, van der Klauw MM, de Witte T, Stauder R, Swinkels DW, Wolffenbuttel BHR, Huls G.

Haematologica. 2019 Mar;104(3):468-476. doi: 10.3324/haematol.2018.195552. Epub 2018 Oct 11.


Study protocol: a randomised controlled trial on the clinical effects of levothyroxine treatment for subclinical hypothyroidism in people aged 80 years and over.

Du Puy RS, Postmus I, Stott DJ, Blum MR, Poortvliet RKE, Den Elzen WPJ, Peeters RP, van Munster BC, Wolffenbuttel BHR, Westendorp RGJ, Kearney PM, Ford I, Kean S, Messow CM, Watt T, Jukema JW, Dekkers OM, Smit JWA, Rodondi N, Gussekloo J, Mooijaart SP.

BMC Endocr Disord. 2018 Sep 19;18(1):67. doi: 10.1186/s12902-018-0285-8.


[An enlarged thymus associated with Graves' disease].

Wouters MPAM, Wolffenbuttel BHR, Links TP, Groen HJM, Wouters RSME.

Ned Tijdschr Geneeskd. 2018 Jul 20;162. pii: D2905. Dutch.


The need for precision medicine in gestational diabetes mellitus.

Paschou SA, Anagnostis P, Wolffenbuttel BHR, Goulis DG.

Maturitas. 2018 Dec;118:74-75. doi: 10.1016/j.maturitas.2018.07.003. Epub 2018 Jul 23. No abstract available.


[The denosumab dilemma: to be stopped after 5 years or to be continued in patients with osteoporosis?]

Wolffenbuttel BHR, Abma EM, Appelman-Dijkstra NM.

Ned Tijdschr Geneeskd. 2018 May 14;162. pii: D2831. Review. Dutch.


Metformin use during pregnancy: Is it really safe?

Paschou SA, Wolffenbuttel BHR.

J Diabetes. 2018 Dec;10(12):984-985. doi: 10.1111/1753-0407.12813. Epub 2018 Jul 10. No abstract available.


High Diabetes Distress Among Ethnic Minorities Is Not Explained by Metabolic, Cardiovascular, or Lifestyle Factors: Findings From the Dutch Diabetes Pearl Cohort.

Özcan B, Rutters F, Snoek FJ, Roosendaal M, Sijbrands EJ, Elders PJM, Holleman F, Pijl H, Tack CJ, Abbink EJ, de Valk HW, Wolffenbuttel BHR, Stehouwer CDA, Schaper NC, Dekker JM, Schram MT; Diabetes Pearl from the Parelsnoer Initiative.

Diabetes Care. 2018 Sep;41(9):1854-1861. doi: 10.2337/dc17-2181. Epub 2018 Jun 26.


Satiety and gastrointestinal hormones during a Mixed Meal Tolerance Test after gastric bypass surgery: association with plasma amino acid concentrations.

van den Broek M, de Heide LJM, Emous M, Wijma RB, Veeger NJGM, Wolthuis A, Laskewitz AJ, Heiner-Fokkema MR, Muller Kobold AC, Wolffenbuttel BHR, van Beek AP.

Surg Obes Relat Dis. 2018 Aug;14(8):1106-1117. doi: 10.1016/j.soard.2018.05.010. Epub 2018 May 21.


Insights uncovered from experiencing a rise in the incidence of gestational diabetes at a Melbourne hospital. Reply to Ng E, Neff M, Sztal-Mazer S [letter].

Koning SH, van Zanden JJ, Hoogenberg K, Lutgers HL, Klomp AW, Korteweg FJ, van Loon AJ, Wolffenbuttel BHR, van den Berg PP.

Diabetologia. 2018 Aug;61(8):1884-1885. doi: 10.1007/s00125-018-4667-2. Epub 2018 Jun 21. No abstract available.


Medicalising pregnancy with new diagnostic criteria for gestational diabetes mellitus: do we need more evidence? Reply to Venkataraman H and Saravanan P [letter].

Koning SH, van Zanden JJ, Hoogenberg K, Lutgers HL, Klomp AW, Korteweg FJ, van Loon AJ, Wolffenbuttel BHR, van den Berg PP.

Diabetologia. 2018 Aug;61(8):1889-1891. doi: 10.1007/s00125-018-4665-4. Epub 2018 Jun 20. No abstract available.


Long-term self-reported symptom prevalence of early and late dumping in a patient population after sleeve gastrectomy, primary, and revisional gastric bypass surgery.

Emous M, Wolffenbuttel BHR, van Dijk G, Totté E, van Beek AP.

Surg Obes Relat Dis. 2018 Aug;14(8):1173-1181. doi: 10.1016/j.soard.2018.04.011. Epub 2018 Apr 24.


Possible Obesogenic Effects of Bisphenols Accumulation in the Human Brain.

Charisiadis P, Andrianou XD, van der Meer TP, den Dunnen WFA, Swaab DF, Wolffenbuttel BHR, Makris KC, van Vliet-Ostaptchouk JV.

Sci Rep. 2018 May 29;8(1):8186. doi: 10.1038/s41598-018-26498-y.


Skin autofluorescence, a non-invasive biomarker for advanced glycation end products, is not related to the number of pregnancies.

Van Waateringe RP, Truyens L, Van Den Berg PP, Lutgers HL, Wolffenbuttel BHR.

J Diabetes. 2018 Nov;10(11):899-901. doi: 10.1111/1753-0407.12782. Epub 2018 Jun 27. No abstract available.


Blood Eosinophil Count and Metabolic, Cardiac and Pulmonary Outcomes: A Mendelian Randomization Study.

Amini M, Vonk JM, Abbasi A, Prins BP, Bruinenberg M, Franke L, van der Harst P, Navis G, Koppelman GH, Wolffenbuttel BHR, Boezen HM, Snieder H, Chasman DI, Alizadeh BZ.

Twin Res Hum Genet. 2018 Apr;21(2):89-100. doi: 10.1017/thg.2018.6. Epub 2018 Mar 6.


Dietary patterns and physical activity in the metabolically (un)healthy obese: the Dutch Lifelines cohort study.

Slagter SN, Corpeleijn E, van der Klauw MM, Sijtsma A, Swart-Busscher LG, Perenboom CWM, de Vries JHM, Feskens EJM, Wolffenbuttel BHR, Kromhout D, van Vliet-Ostaptchouk JV.

Nutr J. 2018 Feb 12;17(1):18. doi: 10.1186/s12937-018-0319-0.


Unfavourable blood pressure and LDL-cholesterol levels in obese non-diabetic individuals.

Wolffenbuttel BHR, Slagter SN, van Waateringe RP, van Beek AP, van Vliet-Ostaptchouk JV, van der Klauw MM.

Neth J Med. 2017 Nov;75(9):399-411.


New diagnostic criteria for gestational diabetes mellitus and their impact on the number of diagnoses and pregnancy outcomes.

Koning SH, van Zanden JJ, Hoogenberg K, Lutgers HL, Klomp AW, Korteweg FJ, van Loon AJ, Wolffenbuttel BHR, van den Berg PP.

Diabetologia. 2018 Apr;61(4):800-809. doi: 10.1007/s00125-017-4506-x. Epub 2017 Nov 22.


DNA methylation markers associated with type 2 diabetes, fasting glucose and HbA1c levels: a systematic review and replication in a case-control sample of the Lifelines study.

Walaszczyk E, Luijten M, Spijkerman AMW, Bonder MJ, Lutgers HL, Snieder H, Wolffenbuttel BHR, van Vliet-Ostaptchouk JV.

Diabetologia. 2018 Feb;61(2):354-368. doi: 10.1007/s00125-017-4497-7. Epub 2017 Nov 21. Review.


Influence of Storage and Inter- and Intra-Assay Variability on the Measurement of Inflammatory Biomarkers in Population-Based Biobanking.

van Waateringe RP, Muller Kobold AC, van Vliet-Ostaptchouk JV, van der Klauw MM, Koerts J, Anton G, Peters A, Trischler G, Kvaløy K, Naess M, Videm V, Hveem K, Waldenberger M, Koenig W, Wolffenbuttel BHR.

Biopreserv Biobank. 2017 Dec;15(6):512-518. doi: 10.1089/bio.2017.0001. Epub 2017 Nov 13.


Skin autofluorescence improves the Finnish Diabetes Risk Score in the detection of diabetes in a large population-based cohort: The LifeLines Cohort Study.

Fokkens BT, van Waateringe RP, Mulder DJ, Wolffenbuttel BHR, Smit AJ.

Diabetes Metab. 2018 Nov;44(5):424-430. doi: 10.1016/j.diabet.2017.09.002. Epub 2017 Oct 31.


CDC73-Related Disorders: Clinical Manifestations and Case Detection in Primary Hyperparathyroidism.

van der Tuin K, Tops CMJ, Adank MA, Cobben JM, Hamdy NAT, Jongmans MC, Menko FH, van Nesselrooij BPM, Netea-Maier RT, Oosterwijk JC, Valk GD, Wolffenbuttel BHR, Hes FJ, Morreau H.

J Clin Endocrinol Metab. 2017 Dec 1;102(12):4534-4540. doi: 10.1210/jc.2017-01249.


Thyroid function and metabolic syndrome in the population-based LifeLines cohort study.

Wolffenbuttel BHR, Wouters HJCM, Slagter SN, van Waateringe RP, Muller Kobold AC, van Vliet-Ostaptchouk JV, Links TP, van der Klauw MM.

BMC Endocr Disord. 2017 Oct 16;17(1):65. doi: 10.1186/s12902-017-0215-1.


Associations Between Systemic and Local Corticosteroid Use With Metabolic Syndrome and Body Mass Index.

Savas M, Muka T, Wester VL, van den Akker ELT, Visser JA, Braunstahl GJ, Slagter SN, Wolffenbuttel BHR, Franco OH, van Rossum EFC.

J Clin Endocrinol Metab. 2017 Oct 1;102(10):3765-3774. doi: 10.1210/jc.2017-01133.


The current total economic burden of diabetes mellitus in the Netherlands.

Peters ML, Huisman EL, Schoonen M, Wolffenbuttel BHR.

Neth J Med. 2017 Sep;75(7):281-297. Review.


Distribution of Non-Persistent Endocrine Disruptors in Two Different Regions of the Human Brain.

van der Meer TP, Artacho-Cordón F, Swaab DF, Struik D, Makris KC, Wolffenbuttel BHR, Frederiksen H, van Vliet-Ostaptchouk JV.

Int J Environ Res Public Health. 2017 Sep 13;14(9). pii: E1059. doi: 10.3390/ijerph14091059.


Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis.

Wheeler E, Leong A, Liu CT, Hivert MF, Strawbridge RJ, Podmore C, Li M, Yao J, Sim X, Hong J, Chu AY, Zhang W, Wang X, Chen P, Maruthur NM, Porneala BC, Sharp SJ, Jia Y, Kabagambe EK, Chang LC, Chen WM, Elks CE, Evans DS, Fan Q, Giulianini F, Go MJ, Hottenga JJ, Hu Y, Jackson AU, Kanoni S, Kim YJ, Kleber ME, Ladenvall C, Lecoeur C, Lim SH, Lu Y, Mahajan A, Marzi C, Nalls MA, Navarro P, Nolte IM, Rose LM, Rybin DV, Sanna S, Shi Y, Stram DO, Takeuchi F, Tan SP, van der Most PJ, Van Vliet-Ostaptchouk JV, Wong A, Yengo L, Zhao W, Goel A, Martinez Larrad MT, Radke D, Salo P, Tanaka T, van Iperen EPA, Abecasis G, Afaq S, Alizadeh BZ, Bertoni AG, Bonnefond A, Böttcher Y, Bottinger EP, Campbell H, Carlson OD, Chen CH, Cho YS, Garvey WT, Gieger C, Goodarzi MO, Grallert H, Hamsten A, Hartman CA, Herder C, Hsiung CA, Huang J, Igase M, Isono M, Katsuya T, Khor CC, Kiess W, Kohara K, Kovacs P, Lee J, Lee WJ, Lehne B, Li H, Liu J, Lobbens S, Luan J, Lyssenko V, Meitinger T, Miki T, Miljkovic I, Moon S, Mulas A, Müller G, Müller-Nurasyid M, Nagaraja R, Nauck M, Pankow JS, Polasek O, Prokopenko I, Ramos PS, Rasmussen-Torvik L, Rathmann W, Rich SS, Robertson NR, Roden M, Roussel R, Rudan I, Scott RA, Scott WR, Sennblad B, Siscovick DS, Strauch K, Sun L, Swertz M, Tajuddin SM, Taylor KD, Teo YY, Tham YC, Tönjes A, Wareham NJ, Willemsen G, Wilsgaard T, Hingorani AD; EPIC-CVD Consortium; EPIC-InterAct Consortium; Lifelines Cohort Study, Egan J, Ferrucci L, Hovingh GK, Jula A, Kivimaki M, Kumari M, Njølstad I, Palmer CNA, Serrano Ríos M, Stumvoll M, Watkins H, Aung T, Blüher M, Boehnke M, Boomsma DI, Bornstein SR, Chambers JC, Chasman DI, Chen YI, Chen YT, Cheng CY, Cucca F, de Geus EJC, Deloukas P, Evans MK, Fornage M, Friedlander Y, Froguel P, Groop L, Gross MD, Harris TB, Hayward C, Heng CK, Ingelsson E, Kato N, Kim BJ, Koh WP, Kooner JS, Körner A, Kuh D, Kuusisto J, Laakso M, Lin X, Liu Y, Loos RJF, Magnusson PKE, März W, McCarthy MI, Oldehinkel AJ, Ong KK, Pedersen NL, Pereira MA, Peters A, Ridker PM, Sabanayagam C, Sale M, Saleheen D, Saltevo J, Schwarz PE, Sheu WHH, Snieder H, Spector TD, Tabara Y, Tuomilehto J, van Dam RM, Wilson JG, Wilson JF, Wolffenbuttel BHR, Wong TY, Wu JY, Yuan JM, Zonderman AB, Soranzo N, Guo X, Roberts DJ, Florez JC, Sladek R, Dupuis J, Morris AP, Tai ES, Selvin E, Rotter JI, Langenberg C, Barroso I, Meigs JB.

PLoS Med. 2017 Sep 12;14(9):e1002383. doi: 10.1371/journal.pmed.1002383. eCollection 2017 Sep.


TUB gene expression in hypothalamus and adipose tissue and its association with obesity in humans.

Nies VJM, Struik D, Wolfs MGM, Rensen SS, Szalowska E, Unmehopa UA, Fluiter K, van der Meer TP, Hajmousa G, Buurman WA, Greve JW, Rezaee F, Shiri-Sverdlov R, Vonk RJ, Swaab DF, Wolffenbuttel BHR, Jonker JW, van Vliet-Ostaptchouk JV.

Int J Obes (Lond). 2018 Mar;42(3):376-383. doi: 10.1038/ijo.2017.214. Epub 2017 Aug 30.


Individual and partner's level of occupation and the association with HbA1c levels in people with Type 2 diabetes mellitus: the Dutch Diabetes Pearl cohort.

Rutte A, Rauh SP, Schram MT, Nijpels G, DeVries JH, Holleman F, Pijl H, Dekkers OM, Özcan B, Sijbrands EJG, Tack CJ, Abbink EJ, de Valk HW, Silvius B, Wolffenbuttel BHR, Stehouwer CDA, Schaper NC, Dekker JM, Beulens JW, Elders PJM, Rutters F; Diabetes Pearl from the Parelsnoer Initiative.

Diabet Med. 2017 Nov;34(11):1623-1628. doi: 10.1111/dme.13422. Epub 2017 Aug 3.


Somatosensory function in patients with secondary adrenal insufficiency treated with two different doses of hydrocortisone-Results from a randomized controlled trial.

Werumeus Buning J, Konopka KH, Brummelman P, Koerts J, Dullaart RPF, van den Berg G, van der Klauw MM, Tucha O, Wolffenbuttel BHR, van Beek AP.

PLoS One. 2017 Jul 7;12(7):e0180326. doi: 10.1371/journal.pone.0180326. eCollection 2017.


The association between various smoking behaviors, cotinine biomarkers and skin autofluorescence, a marker for advanced glycation end product accumulation.

van Waateringe RP, Mook-Kanamori MJ, Slagter SN, van der Klauw MM, van Vliet-Ostaptchouk JV, Graaff R, Lutgers HL, Suhre K, El-Din Selim MM, Mook-Kanamori DO, Wolffenbuttel BHR.

PLoS One. 2017 Jun 20;12(6):e0179330. doi: 10.1371/journal.pone.0179330. eCollection 2017.


The short- to mid-term symptom prevalence of dumping syndrome after primary gastric-bypass surgery and its impact on health-related quality of life.

Emous M, Wolffenbuttel BHR, Totté E, van Beek AP.

Surg Obes Relat Dis. 2017 Sep;13(9):1489-1500. doi: 10.1016/j.soard.2017.04.028. Epub 2017 Apr 28.


Determination of reference intervals for urinary steroid profiling using a newly validated GC-MS/MS method.

de Jong WHA, Buitenwerf E, Pranger AT, Riphagen IJ, Wolffenbuttel BHR, Kerstens MN, Kema IP.

Clin Chem Lab Med. 2017 Nov 27;56(1):103-112. doi: 10.1515/cclm-2016-1072.


Skin autofluorescence, a non-invasive biomarker for advanced glycation end products, is associated with the metabolic syndrome and its individual components.

van Waateringe RP, Slagter SN, van Beek AP, van der Klauw MM, van Vliet-Ostaptchouk JV, Graaff R, Paterson AD, Lutgers HL, Wolffenbuttel BHR.

Diabetol Metab Syndr. 2017 May 30;9:42. doi: 10.1186/s13098-017-0241-1. eCollection 2017.


Pharmacokinetics of oral hydrocortisone - Results and implications from a randomized controlled trial.

Werumeus Buning J, Touw DJ, Brummelman P, Dullaart RPF, van den Berg G, van der Klauw MM, Kamp J, Wolffenbuttel BHR, van Beek AP.

Metabolism. 2017 Jun;71:7-16. doi: 10.1016/j.metabol.2017.02.005. Epub 2017 Feb 13.


Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.

Justice AE, Winkler TW, Feitosa MF, Graff M, Fisher VA, Young K, Barata L, Deng X, Czajkowski J, Hadley D, Ngwa JS, Ahluwalia TS, Chu AY, Heard-Costa NL, Lim E, Perez J, Eicher JD, Kutalik Z, Xue L, Mahajan A, Renström F, Wu J, Qi Q, Ahmad S, Alfred T, Amin N, Bielak LF, Bonnefond A, Bragg J, Cadby G, Chittani M, Coggeshall S, Corre T, Direk N, Eriksson J, Fischer K, Gorski M, Neergaard Harder M, Horikoshi M, Huang T, Huffman JE, Jackson AU, Justesen JM, Kanoni S, Kinnunen L, Kleber ME, Komulainen P, Kumari M, Lim U, Luan J, Lyytikäinen LP, Mangino M, Manichaikul A, Marten J, Middelberg RPS, Müller-Nurasyid M, Navarro P, Pérusse L, Pervjakova N, Sarti C, Smith AV, Smith JA, Stančáková A, Strawbridge RJ, Stringham HM, Sung YJ, Tanaka T, Teumer A, Trompet S, van der Laan SW, van der Most PJ, Van Vliet-Ostaptchouk JV, Vedantam SL, Verweij N, Vink JM, Vitart V, Wu Y, Yengo L, Zhang W, Hua Zhao J, Zimmermann ME, Zubair N, Abecasis GR, Adair LS, Afaq S, Afzal U, Bakker SJL, Bartz TM, Beilby J, Bergman RN, Bergmann S, Biffar R, Blangero J, Boerwinkle E, Bonnycastle LL, Bottinger E, Braga D, Buckley BM, Buyske S, Campbell H, Chambers JC, Collins FS, Curran JE, de Borst GJ, de Craen AJM, de Geus EJC, Dedoussis G, Delgado GE, den Ruijter HM, Eiriksdottir G, Eriksson AL, Esko T, Faul JD, Ford I, Forrester T, Gertow K, Gigante B, Glorioso N, Gong J, Grallert H, Grammer TB, Grarup N, Haitjema S, Hallmans G, Hamsten A, Hansen T, Harris TB, Hartman CA, Hassinen M, Hastie ND, Heath AC, Hernandez D, Hindorff L, Hocking LJ, Hollensted M, Holmen OL, Homuth G, Jan Hottenga J, Huang J, Hung J, Hutri-Kähönen N, Ingelsson E, James AL, Jansson JO, Jarvelin MR, Jhun MA, Jørgensen ME, Juonala M, Kähönen M, Karlsson M, Koistinen HA, Kolcic I, Kolovou G, Kooperberg C, Krämer BK, Kuusisto J, Kvaløy K, Lakka TA, Langenberg C, Launer LJ, Leander K, Lee NR, Lind L, Lindgren CM, Linneberg A, Lobbens S, Loh M, Lorentzon M, Luben R, Lubke G, Ludolph-Donislawski A, Lupoli S, Madden PAF, Männikkö R, Marques-Vidal P, Martin NG, McKenzie CA, McKnight B, Mellström D, Menni C, Montgomery GW, Musk AB, Narisu N, Nauck M, Nolte IM, Oldehinkel AJ, Olden M, Ong KK, Padmanabhan S, Peyser PA, Pisinger C, Porteous DJ, Raitakari OT, Rankinen T, Rao DC, Rasmussen-Torvik LJ, Rawal R, Rice T, Ridker PM, Rose LM, Bien SA, Rudan I, Sanna S, Sarzynski MA, Sattar N, Savonen K, Schlessinger D, Scholtens S, Schurmann C, Scott RA, Sennblad B, Siemelink MA, Silbernagel G, Slagboom PE, Snieder H, Staessen JA, Stott DJ, Swertz MA, Swift AJ, Taylor KD, Tayo BO, Thorand B, Thuillier D, Tuomilehto J, Uitterlinden AG, Vandenput L, Vohl MC, Völzke H, Vonk JM, Waeber G, Waldenberger M, Westendorp RGJ, Wild S, Willemsen G, Wolffenbuttel BHR, Wong A, Wright AF, Zhao W, Zillikens MC, Baldassarre D, Balkau B, Bandinelli S, Böger CA, Boomsma DI, Bouchard C, Bruinenberg M, Chasman DI, Chen YD, Chines PS, Cooper RS, Cucca F, Cusi D, Faire U, Ferrucci L, Franks PW, Froguel P, Gordon-Larsen P, Grabe HJ, Gudnason V, Haiman CA, Hayward C, Hveem K, Johnson AD, Wouter Jukema J, Kardia SLR, Kivimaki M, Kooner JS, Kuh D, Laakso M, Lehtimäki T, Marchand LL, März W, McCarthy MI, Metspalu A, Morris AP, Ohlsson C, Palmer LJ, Pasterkamp G, Pedersen O, Peters A, Peters U, Polasek O, Psaty BM, Qi L, Rauramaa R, Smith BH, Sørensen TIA, Strauch K, Tiemeier H, Tremoli E, van der Harst P, Vestergaard H, Vollenweider P, Wareham NJ, Weir DR, Whitfield JB, Wilson JF, Tyrrell J, Frayling TM, Barroso I, Boehnke M, Deloukas P, Fox CS, Hirschhorn JN, Hunter DJ, Spector TD, Strachan DP, van Duijn CM, Heid IM, Mohlke KL, Marchini J, Loos RJF, Kilpeläinen TO, Liu CT, Borecki IB, North KE, Cupples LA.

Nat Commun. 2017 Apr 26;8:14977. doi: 10.1038/ncomms14977.


Genomic analyses identify hundreds of variants associated with age at menarche and support a role for puberty timing in cancer risk.

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Nat Genet. 2017 Jun;49(6):834-841. doi: 10.1038/ng.3841. Epub 2017 Apr 24.


Sex, BMI and age differences in metabolic syndrome: the Dutch Lifelines Cohort Study.

Slagter SN, van Waateringe RP, van Beek AP, van der Klauw MM, Wolffenbuttel BHR, van Vliet-Ostaptchouk JV.

Endocr Connect. 2017 May;6(4):278-288. doi: 10.1530/EC-17-0011. Epub 2017 Apr 18.


Missing heritability: is the gap closing? An analysis of 32 complex traits in the Lifelines Cohort Study.

Nolte IM, van der Most PJ, Alizadeh BZ, de Bakker PI, Boezen HM, Bruinenberg M, Franke L, van der Harst P, Navis G, Postma DS, Rots MG, Stolk RP, Swertz MA, Wolffenbuttel BH, Wijmenga C, Snieder H.

Eur J Hum Genet. 2017 Jun;25(7):877-885. doi: 10.1038/ejhg.2017.50. Epub 2017 Apr 12.


[Hypocortisolism associated with nephrotic syndrome].

Westerdijk RH, Wolffenbuttel BH, Kema IP, Wouters RS.

Ned Tijdschr Geneeskd. 2017;160:D669. Dutch.


Elevated Bone Turnover Markers after Risk-Reducing Salpingo-Oophorectomy in Women at Increased Risk for Breast and Ovarian Cancer.

Fakkert IE, van der Veer E, Abma EM, Lefrandt JD, Wolffenbuttel BH, Oosterwijk JC, Slart RH, Westrik IG, de Bock GH, Mourits MJ.

PLoS One. 2017 Jan 6;12(1):e0169673. doi: 10.1371/journal.pone.0169673. eCollection 2017.


Postpartum glucose follow-up and lifestyle management after gestational diabetes mellitus: general practitioner and patient perspectives.

Koning SH, Lutgers HL, Hoogenberg K, Trompert CA, van den Berg PP, Wolffenbuttel BH.

J Diabetes Metab Disord. 2016 Dec 7;15:56. eCollection 2016.

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