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Items: 1 to 50 of 110

1.

Sustained overexpression of neuropeptide S in the amygdala reduces anxiety-like behavior in rats.

Tillmann S, Skibdal HE, Christiansen SH, Gøtzsche CR, Hassan M, Mathé AA, Wegener G, Woldbye DPD.

Behav Brain Res. 2019 Jul 23;367:28-34. doi: 10.1016/j.bbr.2019.03.039. Epub 2019 Mar 23.

PMID:
30914309
2.

Modulating Dopamine Signaling and Behavior with Chemogenetics: Concepts, Progress, and Challenges.

Runegaard AH, Fitzpatrick CM, Woldbye DPD, Andreasen JT, Sørensen AT, Gether U.

Pharmacol Rev. 2019 Apr;71(2):123-156. doi: 10.1124/pr.117.013995. Review.

PMID:
30814274
3.

Differential effects of chemogenetic inhibition of dopamine and norepinephrine neurons in the mouse 5-choice serial reaction time task.

Fitzpatrick CM, Runegaard AH, Christiansen SH, Hansen NW, Jørgensen SH, McGirr JC, de Diego Ajenjo A, Sørensen AT, Perrier JF, Petersen A, Gether U, Woldbye DPD, Andreasen JT.

Prog Neuropsychopharmacol Biol Psychiatry. 2019 Mar 2;90:264-276. doi: 10.1016/j.pnpbp.2018.12.004. Epub 2018 Dec 6.

PMID:
30529002
4.

The C-terminal flanking peptide of neuropeptide Y (NPY) is not essential for seizure-suppressant actions of prepro-NPY overexpression in male rats.

Soud K, Jørgensen SH, Woldbye DPD, Sørensen AT.

J Neurosci Res. 2019 Mar;97(3):362-372. doi: 10.1002/jnr.24350. Epub 2018 Oct 27.

PMID:
30367522
5.

Neuropeptide Y treatment induces retinal vasoconstriction and causes functional and histological retinal damage in a porcine ischaemia model.

Christiansen AT, Sørensen NB, Haanes KA, Blixt FW, la Cour M, Warfvinge K, Klemp K, Woldbye DPD, Kiilgaard JF.

Acta Ophthalmol. 2018 Dec;96(8):812-820. doi: 10.1111/aos.13806. Epub 2018 Sep 14.

PMID:
30218483
6.

Locomotor- and Reward-Enhancing Effects of Cocaine Are Differentially Regulated by Chemogenetic Stimulation of Gi-Signaling in Dopaminergic Neurons.

Runegaard AH, Sørensen AT, Fitzpatrick CM, Jørgensen SH, Petersen AV, Hansen NW, Weikop P, Andreasen JT, Mikkelsen JD, Perrier JF, Woldbye D, Rickhag M, Wortwein G, Gether U.

eNeuro. 2018 Jun 18;5(3). pii: ENEURO.0345-17.2018. doi: 10.1523/ENEURO.0345-17.2018. eCollection 2018 May-Jun.

7.

Neuropeptide Y is Up-regulated and Induces Antinociception in Cancer-induced Bone Pain.

Diaz-delCastillo M, Christiansen SH, Appel CK, Falk S, Woldbye DPD, Heegaard AM.

Neuroscience. 2018 Aug 1;384:111-119. doi: 10.1016/j.neuroscience.2018.05.025. Epub 2018 May 29.

PMID:
29852245
8.

Gene Therapy for Parkinson's Disease, An Update.

Axelsen TM, Woldbye DPD.

J Parkinsons Dis. 2018;8(2):195-215. doi: 10.3233/JPD-181331.

9.

Localization, distribution, and connectivity of neuropeptide Y in the human and porcine retinas-A comparative study.

Christiansen AT, Kiilgaard JF, Klemp K, Woldbye DPD, Hannibal J.

J Comp Neurol. 2018 Aug 15;526(12):1877-1895. doi: 10.1002/cne.24455. Epub 2018 May 9.

PMID:
29665009
10.

Differential plastic changes in synthesis and binding in the mouse somatostatin system after electroconvulsive stimulation.

Olesen MV, Gøtzsche CR, Christiansen SH, Woldbye DPD.

Acta Neuropsychiatr. 2018 Aug;30(4):192-202. doi: 10.1017/neu.2018.1. Epub 2018 Mar 21.

PMID:
29559016
11.

Prolonged life of human acute hippocampal slices from temporal lobe epilepsy surgery.

Wickham J, Brödjegård NG, Vighagen R, Pinborg LH, Bengzon J, Woldbye DPD, Kokaia M, Andersson M.

Sci Rep. 2018 Mar 7;8(1):4158. doi: 10.1038/s41598-018-22554-9.

12.

Impact of type 1 diabetes mellitus and sitagliptin treatment on the neuropeptide Y system of rat retina.

Campos EJ, Martins J, Brudzewsky D, Correia S, Santiago AR, Woldbye DP, Ambrósio AF.

Clin Exp Ophthalmol. 2018 Sep;46(7):783-795. doi: 10.1111/ceo.13176. Epub 2018 Mar 5.

PMID:
29442423
13.

Neuropeptide Y and its Involvement in Chronic Pain.

Diaz-delCastillo M, Woldbye DPD, Heegaard AM.

Neuroscience. 2018 Sep 1;387:162-169. doi: 10.1016/j.neuroscience.2017.08.050. Epub 2017 Sep 7. Review.

PMID:
28890052
14.

Chemogenetic Modulation of G Protein-Coupled Receptor Signalling in Visual Attention Research.

Jørgensen SH, Fitzpatrick CM, Gether U, Woldbye DPD, Sørensen AT.

Basic Clin Pharmacol Toxicol. 2017 Nov;121(5):373-381. doi: 10.1111/bcpt.12819. Epub 2017 Jul 10. Review.

15.

Exploring the Behavioral and Metabolic Phenotype Generated by Re-Introduction of the Ghrelin Receptor in the Ventral Tegmental Area.

Skov LJ, Jensen M, Christiansen SH, Ratner C, Woldbye DPD, Holst B.

Int J Mol Sci. 2017 Apr 26;18(5). pii: E914. doi: 10.3390/ijms18050914.

16.

Effects of amphetamine and methylphenidate on attentional performance and impulsivity in the mouse 5-Choice Serial Reaction Time Task.

Caballero-Puntiverio M, Fitzpatrick CM, Woldbye DP, Andreasen JT.

J Psychopharmacol. 2017 Feb;31(2):272-283. doi: 10.1177/0269881116684339. Epub 2017 Jan 16.

PMID:
28093027
17.

Theory of Visual Attention (TVA) applied to mice in the 5-choice serial reaction time task.

Fitzpatrick CM, Caballero-Puntiverio M, Gether U, Habekost T, Bundesen C, Vangkilde S, Woldbye DP, Andreasen JT, Petersen A.

Psychopharmacology (Berl). 2017 Mar;234(5):845-855. doi: 10.1007/s00213-016-4520-6. Epub 2017 Jan 9.

PMID:
28070619
18.

Association between genes on chromosome 19p13.2 and panic disorder.

Gregersen NO, Buttenschøn HN, Hedemand A, Nielsen MN, Dahl HA, Kristensen AS, Johansen O, Woldbye DP, Erhardt A, Kruse TA, Wang AG, Børglum AD, Mors O.

Psychiatr Genet. 2016 Dec;26(6):287-292.

PMID:
27610895
19.

MicroRNA 101b Is Downregulated in the Prefrontal Cortex of a Genetic Model of Depression and Targets the Glutamate Transporter SLC1A1 (EAAT3) in Vitro.

Wei YB, Melas PA, Villaescusa JC, Liu JJ, Xu N, Christiansen SH, Elbrønd-Bek H, Woldbye DP, Wegener G, Mathé AA, Lavebratt C.

Int J Neuropsychopharmacol. 2016 Dec 30;19(12). pii: pyw069. doi: 10.1093/ijnp/pyw069. Print 2016 Dec.

20.

DREADDs suppress seizure-like activity in a mouse model of pharmacoresistant epileptic brain tissue.

Avaliani N, Andersson M, Runegaard AH, Woldbye D, Kokaia M.

Gene Ther. 2016 Oct;23(10):760-766. doi: 10.1038/gt.2016.56. Epub 2016 Jul 14.

PMID:
27416078
21.

Decreased spontaneous activity in AMPK α2 muscle specific kinase dead mice is not caused by changes in brain dopamine metabolism.

Møller LL, Sylow L, Gøtzsche CR, Serup AK, Christiansen SH, Weikop P, Kiens B, Woldbye DP, Richter EA.

Physiol Behav. 2016 Oct 1;164(Pt A):300-5. doi: 10.1016/j.physbeh.2016.06.010. Epub 2016 Jun 13.

PMID:
27306083
22.

Optogenetic control of human neurons in organotypic brain cultures.

Andersson M, Avaliani N, Svensson A, Wickham J, Pinborg LH, Jespersen B, Christiansen SH, Bengzon J, Woldbye DP, Kokaia M.

Sci Rep. 2016 Apr 21;6:24818. doi: 10.1038/srep24818.

23.

Translational approach for gene therapy in epilepsy: Model system and unilateral overexpression of neuropeptide Y and Y2 receptors.

Ledri LN, Melin E, Christiansen SH, Gøtzsche CR, Cifra A, Woldbye DP, Kokaia M.

Neurobiol Dis. 2016 Feb;86:52-61. doi: 10.1016/j.nbd.2015.11.014. Epub 2015 Dec 1.

PMID:
26607785
24.

Anxiolytic-Like Effects of Increased Ghrelin Receptor Signaling in the Amygdala.

Jensen M, Ratner C, Rudenko O, Christiansen SH, Skov LJ, Hundahl C, Woldbye DP, Holst B.

Int J Neuropsychopharmacol. 2016 Apr 29;19(5). pii: pyv123. doi: 10.1093/ijnp/pyv123. Print 2016 May.

25.

The role of NPY in learning and memory.

Gøtzsche CR, Woldbye DP.

Neuropeptides. 2016 Feb;55:79-89. doi: 10.1016/j.npep.2015.09.010. Epub 2015 Oct 3. Review.

PMID:
26454711
26.

Candidate genes in panic disorder: meta-analyses of 23 common variants in major anxiogenic pathways.

Howe AS, Buttenschøn HN, Bani-Fatemi A, Maron E, Otowa T, Erhardt A, Binder EB, Gregersen NO, Mors O, Woldbye DP, Domschke K, Reif A, Shlik J, Kõks S, Kawamura Y, Miyashita A, Kuwano R, Tokunaga K, Tanii H, Smoller JW, Sasaki T, Koszycki D, De Luca V.

Mol Psychiatry. 2016 May;21(5):665-79. doi: 10.1038/mp.2015.138. Epub 2015 Sep 22. Review.

PMID:
26390831
27.

[Optogenetics brings hidden neural mechanisms into the light and could become a future therapy].

Axelsen TM, Navntoft CA, Christiansen SH, Dreyer JK, Sørensen JB, Gether U, Woldbye DP.

Ugeskr Laeger. 2015 Aug 17;177(34). pii: V06150501. Review. Danish.

PMID:
26320592
28.

Activation of Neuropeptide Y Receptors Modulates Retinal Ganglion Cell Physiology and Exerts Neuroprotective Actions In Vitro.

Martins J, Elvas F, Brudzewsky D, Martins T, Kolomiets B, Tralhão P, Gøtzsche CR, Cavadas C, Castelo-Branco M, Woldbye DP, Picaud S, Santiago AR, Ambrósio AF.

ASN Neuro. 2015 Aug 26;7(4). pii: 1759091415598292. doi: 10.1177/1759091415598292. Print 2015 Jul-Aug.

29.

Epigenetic regulation of Dnmt3a and Arc gene expression after electroconvulsive stimulation in the rat.

Dyrvig M, Gøtzsche CR, Woldbye DP, Lichota J.

Mol Cell Neurosci. 2015 Jul;67:137-43. doi: 10.1016/j.mcn.2015.06.011. Epub 2015 Jun 30.

PMID:
26141855
30.

Differential Effect of Neuropeptides on Excitatory Synaptic Transmission in Human Epileptic Hippocampus.

Ledri M, Sørensen AT, Madsen MG, Christiansen SH, Ledri LN, Cifra A, Bengzon J, Lindberg E, Pinborg LH, Jespersen B, Gøtzsche CR, Woldbye DP, Andersson M, Kokaia M.

J Neurosci. 2015 Jul 1;35(26):9622-31. doi: 10.1523/JNEUROSCI.3973-14.2015.

31.

Anxiolytic-like effects after vector-mediated overexpression of neuropeptide Y in the amygdala and hippocampus of mice.

Christiansen SH, Olesen MV, Gøtzsche CR, Woldbye DP.

Neuropeptides. 2014 Dec;48(6):335-44. doi: 10.1016/j.npep.2014.09.004. Epub 2014 Sep 16.

PMID:
25267070
32.

Neuropeptide Y-stimulated [(35) S]GTPγs functional binding is reduced in the hippocampus after kainate-induced seizures in mice.

Elbrønd-Bek H, Olling JD, Gøtzsche CR, Waterfield A, Wörtwein G, Woldbye DP.

Synapse. 2014 Oct;68(10):427-36. doi: 10.1002/syn.21762. Epub 2014 Jul 9.

PMID:
24985894
33.

Temporal gene expression profile after acute electroconvulsive stimulation in the rat.

Dyrvig M, Christiansen SH, Woldbye DP, Lichota J.

Gene. 2014 Apr 10;539(1):8-14. doi: 10.1016/j.gene.2014.01.072. Epub 2014 Feb 8.

PMID:
24518690
34.

Are TMEM genes potential candidate genes for panic disorder?

Gregersen NO, Buttenschøn HN, Hedemand A, Dahl HA, Kristensen AS, Clementsen B, Woldbye DP, Koefoed P, Erhardt A, Kruse TA, Wang AG, Børglum AD, Mors O.

Psychiatr Genet. 2014 Feb;24(1):37-41. doi: 10.1097/YPG.0000000000000022.

PMID:
24362369
35.

Addiction-related effects of DOV 216,303 and cocaine: A comparative study in the mouse.

Sørensen G, Husum H, Brennum LT, Bundgaard C, Montezinho LC, Mørk A, Wörtwein G, Woldbye DP.

Basic Clin Pharmacol Toxicol. 2014 Jun;114(6):451-9. doi: 10.1111/bcpt.12182. Epub 2014 Jan 16.

36.

A peptide antagonist of ErbB receptors, Inherbin3, induces neurite outgrowth from rat cerebellar granule neurons through ErbB1 inhibition.

Xu R, Pankratova S, Christiansen SH, Woldbye D, Højland A, Bock E, Berezin V.

Neurochem Res. 2013 Dec;38(12):2550-8. doi: 10.1007/s11064-013-1166-1. Epub 2013 Oct 17.

PMID:
24132641
37.

Membrane-permeable C-terminal dopamine transporter peptides attenuate amphetamine-evoked dopamine release.

Rickhag M, Owens WA, Winkler MT, Strandfelt KN, Rathje M, Sørensen G, Andresen B, Madsen KL, Jørgensen TN, Wörtwein G, Woldbye DP, Sitte H, Daws LC, Gether U.

J Biol Chem. 2013 Sep 20;288(38):27534-44. doi: 10.1074/jbc.M112.441295. Epub 2013 Jul 24.

38.

PICK1 deficiency impairs secretory vesicle biogenesis and leads to growth retardation and decreased glucose tolerance.

Holst B, Madsen KL, Jansen AM, Jin C, Rickhag M, Lund VK, Jensen M, Bhatia V, Sørensen G, Madsen AN, Xue Z, Møller SK, Woldbye D, Qvortrup K, Huganir R, Stamou D, Kjærulff O, Gether U.

PLoS Biol. 2013;11(4):e1001542. doi: 10.1371/journal.pbio.1001542. Epub 2013 Apr 23.

39.

Electroconvulsive stimulation reverses anhedonia and cognitive impairments in rats exposed to chronic mild stress.

Henningsen K, Woldbye DP, Wiborg O.

Eur Neuropsychopharmacol. 2013 Dec;23(12):1789-94. doi: 10.1016/j.euroneuro.2013.03.011. Epub 2013 Apr 15.

PMID:
23597878
40.

A C-terminal PDZ domain-binding sequence is required for striatal distribution of the dopamine transporter.

Rickhag M, Hansen FH, Sørensen G, Strandfelt KN, Andresen B, Gotfryd K, Madsen KL, Vestergaard-Klewe I, Ammendrup-Johnsen I, Eriksen J, Newman AH, Füchtbauer EM, Gomeza J, Woldbye DP, Wörtwein G, Gether U.

Nat Commun. 2013;4:1580. doi: 10.1038/ncomms2568. Erratum in: Nat Commun. 2013;4:2589.

41.

Neuropeptide Y Y5 receptor antagonism causes faster extinction and attenuates reinstatement in cocaine-induced place preference.

Sørensen G, Wörtwein G, Fink-Jensen A, Woldbye DP.

Pharmacol Biochem Behav. 2013 Apr;105:151-6. doi: 10.1016/j.pbb.2013.02.010. Epub 2013 Feb 27.

PMID:
23454535
42.

Neuropeptide Y genes and suicidal behaviour among schizophrenic patients.

Wang AG, Koefoed P, Jacoby AS, Woldbye D, Rasmussen HB, Timm S, Dam H, Jakobsen KD, Nordentoft M, Jürgens G, Sorensen HJ, Garsdal O, Hvid M, Werge T.

Psychiatr Genet. 2013 Jun;23(3):139-40. doi: 10.1097/YPG.0b013e32835d70ed. No abstract available.

PMID:
23407263
43.

Galanin promotes neuronal differentiation in murine subventricular zone cell cultures.

Agasse F, Xapelli S, Coronas V, Christiansen SH, Rosa AI, Sardá-Arroyo L, Santos T, Ferreira R, Schitine C, Harnois T, Bourmeyster N, Bragança J, Bernardino L, Malva JO, Woldbye DP.

Stem Cells Dev. 2013 Jun 1;22(11):1693-708. doi: 10.1089/scd.2012.0161. Epub 2013 Mar 1.

PMID:
23327619
44.

Methamphetamine-induced changes in the mice hippocampal neuropeptide Y system: implications for memory impairment.

Gonçalves J, Baptista S, Olesen MV, Fontes-Ribeiro C, Malva JO, Woldbye DP, Silva AP.

J Neurochem. 2012 Dec;123(6):1041-53. doi: 10.1111/jnc.12052. Epub 2012 Nov 1.

45.

Replication and meta-analysis of TMEM132D gene variants in panic disorder.

Erhardt A, Akula N, Schumacher J, Czamara D, Karbalai N, Müller-Myhsok B, Mors O, Borglum A, Kristensen AS, Woldbye DP, Koefoed P, Eriksson E, Maron E, Metspalu A, Nurnberger J, Philibert RA, Kennedy J, Domschke K, Reif A, Deckert J, Otowa T, Kawamura Y, Kaiya H, Okazaki Y, Tanii H, Tokunaga K, Sasaki T, Ioannidis JP, McMahon FJ, Binder EB.

Transl Psychiatry. 2012 Sep 4;2:e156. doi: 10.1038/tp.2012.85.

46.

An allosteric enhancer of M₄ muscarinic acetylcholine receptor function inhibits behavioral and neurochemical effects of cocaine.

Dencker D, Weikop P, Sørensen G, Woldbye DP, Wörtwein G, Wess J, Fink-Jensen A.

Psychopharmacology (Berl). 2012 Nov;224(2):277-87. doi: 10.1007/s00213-012-2751-8. Epub 2012 May 31.

47.

Epigenetic regulation of Arc and c-Fos in the hippocampus after acute electroconvulsive stimulation in the rat.

Dyrvig M, Hansen HH, Christiansen SH, Woldbye DP, Mikkelsen JD, Lichota J.

Brain Res Bull. 2012 Aug 1;88(5):507-13. doi: 10.1016/j.brainresbull.2012.05.004. Epub 2012 May 18.

PMID:
22613772
48.

Mice lacking neuropeptide Y show increased sensitivity to cocaine.

Sørensen G, Woldbye DP.

Synapse. 2012 Sep;66(9):840-3. doi: 10.1002/syn.21568. Epub 2012 May 23.

PMID:
22544368
49.

Association of the leucine-7 to proline-7 variation in the signal sequence of neuropeptide Y with major depression.

Koefoed P, Woldbye DP, Hansen TV, Eplov LF, Christiansen SH, Mors O, Kessing LV, Werge T, Kaipio K, Pesonen U, Fahmy T, Mellerup E, Jakobsen KD, Hansen ES, Knudsen GM, Bukh JD, Bock C, Lindberg C, Kristensen AS, Dam H, Nordentoft M, Als TD, Wang AG, Gether U, Rehfeld JF, Bolwig TG.

Acta Neuropsychiatr. 2012 Apr;24(2):81-90. doi: 10.1111/j.1601-5215.2011.00600.x.

PMID:
26952950
50.

Neuropeptide Y Y5 receptor antagonism attenuates cocaine-induced effects in mice.

Sørensen G, Jensen M, Weikop P, Dencker D, Christiansen SH, Loland CJ, Bengtsen CH, Petersen JH, Fink-Jensen A, Wörtwein G, Woldbye DP.

Psychopharmacology (Berl). 2012 Aug;222(4):565-77. doi: 10.1007/s00213-012-2651-y. Epub 2012 Feb 25.

PMID:
22367168

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