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Items: 6

1.

Population Pharmacokinetics of Mefloquine Intermittent Preventive Treatment for Malaria in Pregnancy in Gabon.

Ramharter M, Schwab M, Mombo-Ngoma G, Zoleko Manego R, Akerey-Diop D, Basra A, Mackanga JR, Würbel H, Wojtyniak JG, Gonzalez R, Hofmann U, Geditz M, Matsiegui PB, Kremsner PG, Menendez C, Kerb R, Lehr T.

Antimicrob Agents Chemother. 2019 Jan 29;63(2). pii: e01113-18. doi: 10.1128/AAC.01113-18. Print 2019 Feb.

2.

Can toxicokinetics of (synthetic) cannabinoids in pigs after pulmonary administration be upscaled to humans by allometric techniques?

Schaefer N, Wojtyniak JG, Kroell AK, Koerbel C, Laschke MW, Lehr T, Menger MD, Maurer HH, Meyer MR, Schmidt PH.

Biochem Pharmacol. 2018 Sep;155:403-418. doi: 10.1016/j.bcp.2018.07.029. Epub 2018 Jul 24.

PMID:
30048626
3.

Inhibition of Cyclin-Dependent Kinase 5: A Strategy to Improve Sorafenib Response in Hepatocellular Carcinoma Therapy.

Ardelt MA, Fröhlich T, Martini E, Müller M, Kanitz V, Atzberger C, Cantonati P, Meßner M, Posselt L, Lehr T, Wojtyniak JG, Ulrich M, Arnold GJ, König L, Parazzoli D, Zahler S, Rothenfußer S, Mayr D, Gerbes A, Scita G, Vollmar AM, Pachmayr J.

Hepatology. 2019 Jan;69(1):376-393. doi: 10.1002/hep.30190. Epub 2018 Dec 22.

4.

How to disentangle psychobiological stress reactivity and recovery: A comparison of model-based and non-compartmental analyses of cortisol concentrations.

Miller R, Wojtyniak JG, Weckesser LJ, Alexander NC, Engert V, Lehr T.

Psychoneuroendocrinology. 2018 Apr;90:194-210. doi: 10.1016/j.psyneuen.2017.12.019. Epub 2017 Dec 29.

PMID:
29370954
5.

A physiologically based pharmacokinetic (PBPK) parent-metabolite model of the chemotherapeutic zoptarelin doxorubicin-integration of in vitro results, Phase I and Phase II data and model application for drug-drug interaction potential analysis.

Hanke N, Teifel M, Moj D, Wojtyniak JG, Britz H, Aicher B, Sindermann H, Ammer N, Lehr T.

Cancer Chemother Pharmacol. 2018 Feb;81(2):291-304. doi: 10.1007/s00280-017-3495-2. Epub 2017 Dec 4.

PMID:
29204687
6.

Pharmacokinetics of (synthetic) cannabinoids in pigs and their relevance for clinical and forensic toxicology.

Schaefer N, Wojtyniak JG, Kettner M, Schlote J, Laschke MW, Ewald AH, Lehr T, Menger MD, Maurer HH, Schmidt PH.

Toxicol Lett. 2016 Jun 24;253:7-16. doi: 10.1016/j.toxlet.2016.04.021. Epub 2016 Apr 23.

PMID:
27113702

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