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Items: 1 to 50 of 74

1.

Syrosingopine sensitizes cancer cells to killing by metformin.

Benjamin D, Colombi M, Hindupur SK, Betz C, Lane HA, El-Shemerly MY, Lu M, Quagliata L, Terracciano L, Moes S, Sharpe T, Wodnar-Filipowicz A, Moroni C, Hall MN.

Sci Adv. 2016 Dec 23;2(12):e1601756. doi: 10.1126/sciadv.1601756. eCollection 2016 Dec.

2.

Decreased NK-cell tumour immunosurveillance consequent to JAK inhibition enhances metastasis in breast cancer models.

Bottos A, Gotthardt D, Gill JW, Gattelli A, Frei A, Tzankov A, Sexl V, Wodnar-Filipowicz A, Hynes NE.

Nat Commun. 2016 Jul 13;7:12258. doi: 10.1038/ncomms12258.

3.

FLT3 activation improves post-myocardial infarction remodeling involving a cytoprotective effect on cardiomyocytes.

Pfister O, Lorenz V, Oikonomopoulos A, Xu L, Häuselmann SP, Mbah C, Kaufmann BA, Liao R, Wodnar-Filipowicz A, Kuster GM.

J Am Coll Cardiol. 2014 Mar 18;63(10):1011-9. doi: 10.1016/j.jacc.2013.08.1647. Epub 2013 Oct 30.

4.

STAT3 mutations indicate the presence of subclinical T-cell clones in a subset of aplastic anemia and myelodysplastic syndrome patients.

Jerez A, Clemente MJ, Makishima H, Rajala H, Gómez-Seguí I, Olson T, McGraw K, Przychodzen B, Kulasekararaj A, Afable M, Husseinzadeh HD, Hosono N, LeBlanc F, Lagström S, Zhang D, Ellonen P, Tichelli A, Nissen C, Lichtin AE, Wodnar-Filipowicz A, Mufti GJ, List AF, Mustjoki S, Loughran TP Jr, Maciejewski JP.

Blood. 2013 Oct 3;122(14):2453-9. doi: 10.1182/blood-2013-04-494930. Epub 2013 Aug 7. Erratum in: Blood. 2014 May 22;123(21):3364.

5.

Post-transcriptional regulation of ULBP1 ligand for the activating immunoreceptor NKG2D involves 3' untranslated region.

Himmelreich H, Mathys A, Wodnar-Filipowicz A, Kalberer CP.

Hum Immunol. 2011 Jun;72(6):470-8. doi: 10.1016/j.humimm.2011.03.005. Epub 2011 Mar 13.

PMID:
21406206
6.

Good manufacturing practice-compliant cell sorting and large-scale expansion of single KIR-positive alloreactive human natural killer cells for multiple infusions to leukemia patients.

Siegler U, Meyer-Monard S, Jörger S, Stern M, Tichelli A, Gratwohl A, Wodnar-Filipowicz A, Kalberer CP.

Cytotherapy. 2010 Oct;12(6):750-63. doi: 10.3109/14653241003786155.

PMID:
20491532
7.

Flt3 ligand-receptor interaction is important for maintenance of early thymic progenitor numbers in steady-state thymopoiesis.

Kenins L, Gill JW, Holländer GA, Wodnar-Filipowicz A.

Eur J Immunol. 2010 Jan;40(1):81-90. doi: 10.1002/eji.200839213.

8.

Human acute myeloid leukemia CD34+CD38- stem cells are susceptible to allorecognition and lysis by single KIR-expressing natural killer cells.

Langenkamp U, Siegler U, Jörger S, Diermayr S, Gratwohl A, Kalberer CP, Wodnar-Filipowicz A.

Haematologica. 2009 Nov;94(11):1590-4. doi: 10.3324/haematol.2009.005967. Epub 2009 Jul 16.

9.

A freeway to stem cells?

Gratwohl A, Wodnar-Filipowicz A.

Blood. 2008 Aug 15;112(4):923-4. doi: 10.1182/blood-2008-05-156661. No abstract available.

10.

Intrathymic expression of Flt3 ligand enhances thymic recovery after irradiation.

Kenins L, Gill JW, Boyd RL, Holländer GA, Wodnar-Filipowicz A.

J Exp Med. 2008 Mar 17;205(3):523-31. doi: 10.1084/jem.20072065. Epub 2008 Feb 25.

11.

NKG2D ligand expression in AML increases in response to HDAC inhibitor valproic acid and contributes to allorecognition by NK-cell lines with single KIR-HLA class I specificities.

Diermayr S, Himmelreich H, Durovic B, Mathys-Schneeberger A, Siegler U, Langenkamp U, Hofsteenge J, Gratwohl A, Tichelli A, Paluszewska M, Wiktor-Jedrzejczak W, Kalberer CP, Wodnar-Filipowicz A.

Blood. 2008 Feb 1;111(3):1428-36. Epub 2007 Nov 9.

12.

Clinical stem-cell sources contain CD8+CD3+ T-cell receptor-negative cells that facilitate bone marrow repopulation with hematopoietic stem cells.

Bridenbaugh S, Kenins L, Bouliong-Pillai E, Kalberer CP, Shklovskaya E, Gratwohl A, Wodnar-Filipowicz A.

Blood. 2008 Feb 1;111(3):1735-8. Epub 2007 Nov 5.

13.

Function of natural killer cells in immune defence against human leukaemia.

Wodnar-Filipowicz A, Kalberer CP.

Swiss Med Wkly. 2007 Mar 2;137 Suppl 155:25S-30S.

PMID:
17874497
14.

Differentiation-promoting drugs up-regulate NKG2D ligand expression and enhance the susceptibility of acute myeloid leukemia cells to natural killer cell-mediated lysis.

Rohner A, Langenkamp U, Siegler U, Kalberer CP, Wodnar-Filipowicz A.

Leuk Res. 2007 Oct;31(10):1393-402. Epub 2007 Mar 27.

PMID:
17391757
15.

The effect of silencing NKG2D through RNA interference on receptor functions in interleukin-2-activated human natural killer cells.

Baeriswyl V, Wodnar-Filipowicz A, Kalberer CP.

Haematologica. 2006 Nov;91(11):1538-41. Epub 2006 Oct 17.

16.

Function of natural killer cells in immune defence against human leukaemia.

Wodnar-Filipowicz A, Kalberer CP.

Swiss Med Wkly. 2006 Jun 10;136(23-24):359-64. Review.

PMID:
16874940
17.

Activated natural killer cells from patients with acute myeloid leukemia are cytotoxic against autologous leukemic blasts in NOD/SCID mice.

Siegler U, Kalberer CP, Nowbakht P, Sendelov S, Meyer-Monard S, Wodnar-Filipowicz A.

Leukemia. 2005 Dec;19(12):2215-22.

PMID:
16224486
18.

Three-dimensional perfusion culture of human bone marrow cells and generation of osteoinductive grafts.

Braccini A, Wendt D, Jaquiery C, Jakob M, Heberer M, Kenins L, Wodnar-Filipowicz A, Quarto R, Martin I.

Stem Cells. 2005 Sep;23(8):1066-72. Epub 2005 Jul 7.

19.

Ligands for natural killer cell-activating receptors are expressed upon the maturation of normal myelomonocytic cells but at low levels in acute myeloid leukemias.

Nowbakht P, Ionescu MC, Rohner A, Kalberer CP, Rossy E, Mori L, Cosman D, De Libero G, Wodnar-Filipowicz A.

Blood. 2005 May 1;105(9):3615-22. Epub 2005 Jan 18.

20.

Gene silencing by lentivirus-mediated delivery of siRNA in human CD34+ cells.

Schomber T, Kalberer CP, Wodnar-Filipowicz A, Skoda RC.

Blood. 2004 Jun 15;103(12):4511-3. Epub 2004 Feb 26.

21.

Reconstitution of dendritic and natural killer-cell subsets after allogeneic stem cell transplantation: effects of endogenous flt3 ligand.

Chklovskaia E, Nowbakht P, Nissen C, Gratwohl A, Bargetzi M, Wodnar-Filipowicz A.

Blood. 2004 May 15;103(10):3860-8. Epub 2004 Feb 5.

22.

Flt3 ligand: role in control of hematopoietic and immune functions of the bone marrow.

Wodnar-Filipowicz A.

News Physiol Sci. 2003 Dec;18:247-51. Review.

PMID:
14614158
23.

Human NK cell development in NOD/SCID mice receiving grafts of cord blood CD34+ cells.

Kalberer CP, Siegler U, Wodnar-Filipowicz A.

Blood. 2003 Jul 1;102(1):127-35. Epub 2003 Mar 13.

24.

[Plasticity of stem cells: a change of paradigm?].

Wodnar-Filipowicz A.

Ther Umsch. 2002 Nov;59(11):565-70. Review. German.

PMID:
12498047
25.

Effect of preeclampsia on umbilical cord blood hematopoietic progenitor-stem cells.

Surbek DV, Danzer E, Steinmann C, Tichelli A, Wodnar-Filipowicz A, Hahn S, Holzgreve W.

Am J Obstet Gynecol. 2001 Sep;185(3):725-9.

PMID:
11568804
26.

Intracellular Fas ligand is elevated in T lymphocytes in severe aplastic anaemia.

Luther-Wyrsch A, Nissen C, Wodnar-Filipowicz A.

Br J Haematol. 2001 Sep;114(4):884-90.

PMID:
11564081
27.

Stable transduction with lentiviral vectors and amplification of immature hematopoietic progenitors from cord blood of preterm human fetuses.

Luther-Wyrsch A, Costello E, Thali M, Buetti E, Nissen C, Surbek D, Holzgreve W, Gratwohl A, Tichelli A, Wodnar-Filipowicz A.

Hum Gene Ther. 2001 Mar 1;12(4):377-89.

PMID:
11242530
28.
29.

Fetal hematopoietic stem cells: in vitro expansion and transduction using lentiviral vectors.

Luther-Wyrsch A, Nissen C, Surbek DV, Holzgreve W, Costello E, Thali M, Buetti E, Wodnar-Filipowicz A.

Ernst Schering Res Found Workshop. 2001;(33):123-44. No abstract available.

PMID:
11105258
30.

Natural killer-type receptors for HLA class I antigens are clonally expressed in lymphoproliferative disorders of natural killer and T-cell type.

Hoffmann T, De Libero G, Colonna M, Wodnar-Filipowicz A, Passweg J, Favre G, Gratwohl A, Tichelli A.

Br J Haematol. 2000 Sep;110(3):525-36.

PMID:
10997961
31.

Decreased cord blood yield in post-term pregnancy: a comparative study.

Surbek DV, Steinmann C, Tichelli A, Wodnar-Filipowicz A, Holzgreve W.

Br J Haematol. 2000 Jul;110(1):235-7. No abstract available.

PMID:
10931007
32.

Preterm birth and the availability of cord blood for HPC transplantation.

Surbek DV, Holzgreve W, Steinmann C, Hahn S, Gratwohl A, Wodnar-Filipowicz A, Tichelli A.

Transfusion. 2000 Jul;40(7):817-20.

PMID:
10924609
33.

Chronic overexpression of membrane-bound flt3 ligand by T lymphocytes in severe aplastic anaemia.

Pfister O, Chklovskaia E, Jansen W, Mészáros K, Nissen C, Rahner C, Hurwitz N, Bogatcheva N, Lyman SD, Wodnar-Filipowicz A.

Br J Haematol. 2000 Apr;109(1):211-20.

PMID:
10848802
34.
35.

Repeated peripheral stem cell mobilization in healthy donors: time-dependent changes in mobilization efficiency.

Tichelli A, Passweg J, Hoffmann T, Gregor M, Kühne T, Favre G, Wodnar-Filipowicz A, Gratwohl A.

Br J Haematol. 1999 Jul;106(1):152-8.

PMID:
10444178
36.

High incidence of transiently appearing complement-sensitive bone marrow precursor cells in patients with severe aplastic anemia--A possible role of high endogenous IL-2 in their suppression.

Nissen C, Tichelli A, Gratwohl A, Warthmann C, Moser Y, dalle Carbonare V, Sendelov S, Chklovskaia E, Jansen W, Wodnar-Filipowicz A, Sadallah S, Speck B.

Acta Haematol. 1999;101(4):165-72.

PMID:
10436296
37.

Umbilical cord blood from preterm human fetuses is rich in committed and primitive hematopoietic progenitors with high proliferative and self-renewal capacity.

Wyrsch A, dalle Carbonare V, Jansen W, Chklovskaia E, Nissen C, Surbek D, Holzgreve W, Tichelli A, Wodnar-Filipowicz A.

Exp Hematol. 1999 Aug;27(8):1338-45.

PMID:
10428511
38.

Successful treatment of refractory acquired pure red cell aplasia (PRCA) by allogeneic bone marrow transplantation.

Müller BU, Tichelli A, Passweg JR, Nissen C, Wodnar-Filipowicz A, Gratwohl A.

Bone Marrow Transplant. 1999 Jun;23(11):1205-7.

39.
40.

Synergy of growth factors during mobilization of peripheral blood precursor cells with recombinant human Flt3-ligand and granulocyte colony-stimulating factor in rabbits.

Pless M, Wodnar-Filipowicz A, John L, Baldomero H, Lyman SD, Nissen C, Gratwohl A.

Exp Hematol. 1999 Jan;27(1):155-61.

PMID:
9923454
41.

[Establishing an umbilical cord blood bank for unrelated allogenic stem cell transplantation].

Tichelli A, Surbek D, Huxol H, Schmolck C, John L, Wicki R, Hoffmann T, Wodnar-Filipowicz A, Passweg J, Kühne T, Imbach P, Holzgreve W, Gratwohl A.

Schweiz Med Wochenschr. 1998 Oct 17;128(42):1598-601. German.

PMID:
9824889
42.

Quantitative immunophenotypic characterization, cryopreservation, and enrichment of second- and third-trimester human fetal cord blood hematopoietic stem cells (progenitor cells).

Surbek DV, Holzgreve W, Jansen W, Heim D, Garritsen H, Nissen C, Wodnar-Filipowicz A.

Am J Obstet Gynecol. 1998 Nov;179(5):1228-33.

PMID:
9822506
43.

FLT-3 ligand provides hematopoietic protection from total body irradiation in rabbits.

Gratwohl A, John L, Baldomero H, Roth J, Tichelli A, Nissen C, Lyman SD, Wodnar-Filipowicz A.

Blood. 1998 Aug 1;92(3):765-9.

44.
45.

Repeated treatment with horse antilymphocyte globulin for severe aplastic anaemia.

Tichelli A, Passweg J, Nissen C, Bargetzi M, Hoffmann T, Wodnar-Filipowicz A, Signer E, Speck B, Gratwohl A.

Br J Haematol. 1998 Feb;100(2):393-400.

PMID:
9488634
46.

Effect of flt3 ligand on in vitro growth and expansion of colony-forming bone marrow cells from patients with aplastic anemia.

Wodnar-Filipowicz A, Chklovskaia E, Manz CY, Lyman SD, Nissen C.

Exp Hematol. 1997 Jul;25(7):573-81.

PMID:
9216732
47.

T-cell receptor beta chain variability in bone marrow and peripheral blood in severe acquired aplastic anemia.

Manz CY, Dietrich PY, Schnuriger V, Nissen C, Wodnar-Filipowicz A.

Blood Cells Mol Dis. 1997;23(1):110-22.

PMID:
9215756
48.

Flt3 ligand level reflects hematopoietic progenitor cell function in aplastic anemia and chemotherapy-induced bone marrow aplasia.

Wodnar-Filipowicz A, Lyman SD, Gratwohl A, Tichelli A, Speck B, Nissen C.

Blood. 1996 Dec 15;88(12):4493-9.

49.
50.

[Somatic gene therapy: perspectives in the use of hematopoietic stem cells].

Wodnar-Filipowicz A.

Praxis (Bern 1994). 1996 Apr 9;85(15):469-72. Review. German. No abstract available.

PMID:
8657985

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