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Items: 17

1.

Appraisal Support from Natural Mentors, Self-worth, and Psychological Distress: Examining the Experiences of Underrepresented Students Transitioning Through College.

Hurd NM, Albright J, Wittrup A, Negrete A, Billingsley J.

J Youth Adolesc. 2018 May;47(5):1100-1112. doi: 10.1007/s10964-017-0798-x. Epub 2017 Dec 27.

PMID:
29282606
2.

Knocking down disease: a progress report on siRNA therapeutics.

Wittrup A, Lieberman J.

Nat Rev Genet. 2015 Sep;16(9):543-52. doi: 10.1038/nrg3978. Review.

3.

Gene Knockdown by EpCAM Aptamer-siRNA Chimeras Suppresses Epithelial Breast Cancers and Their Tumor-Initiating Cells.

Gilboa-Geffen A, Hamar P, Le MT, Wheeler LA, Trifonova R, Petrocca F, Wittrup A, Lieberman J.

Mol Cancer Ther. 2015 Oct;14(10):2279-91. doi: 10.1158/1535-7163.MCT-15-0201-T. Epub 2015 Aug 11.

4.

Visualizing lipid-formulated siRNA release from endosomes and target gene knockdown.

Wittrup A, Ai A, Liu X, Hamar P, Trifonova R, Charisse K, Manoharan M, Kirchhausen T, Lieberman J.

Nat Biotechnol. 2015 Aug;33(8):870-6. doi: 10.1038/nbt.3298. Epub 2015 Jul 20.

5.

Exosome uptake depends on ERK1/2-heat shock protein 27 signaling and lipid Raft-mediated endocytosis negatively regulated by caveolin-1.

Svensson KJ, Christianson HC, Wittrup A, Bourseau-Guilmain E, Lindqvist E, Svensson LM, Mörgelin M, Belting M.

J Biol Chem. 2013 Jun 14;288(24):17713-24. doi: 10.1074/jbc.M112.445403. Epub 2013 May 7.

6.

Studies of proteoglycan involvement in CPP-mediated delivery.

Wittrup A, Zhang SH, Belting M.

Methods Mol Biol. 2011;683:99-115. doi: 10.1007/978-1-60761-919-2_8.

PMID:
21053125
7.

Magnetic nanoparticle-based isolation of endocytic vesicles reveals a role of the heat shock protein GRP75 in macromolecular delivery.

Wittrup A, Zhang SH, Svensson KJ, Kucharzewska P, Johansson MC, Mörgelin M, Belting M.

Proc Natl Acad Sci U S A. 2010 Jul 27;107(30):13342-7. doi: 10.1073/pnas.1002622107. Epub 2010 Jul 12.

8.

ScFv antibody-induced translocation of cell-surface heparan sulfate proteoglycan to endocytic vesicles: evidence for heparan sulfate epitope specificity and role of both syndecan and glypican.

Wittrup A, Zhang SH, ten Dam GB, van Kuppevelt TH, Bengtson P, Johansson M, Welch J, Mörgelin M, Belting M.

J Biol Chem. 2009 Nov 20;284(47):32959-67. doi: 10.1074/jbc.M109.036129. Epub 2009 Sep 25.

9.

Macromolecular drug delivery: basic principles and therapeutic applications.

Belting M, Wittrup A.

Mol Biotechnol. 2009 Sep;43(1):89-94. doi: 10.1007/s12033-009-9185-5. Epub 2009 May 28. Review.

PMID:
19475521
10.
11.

Developments in macromolecular drug delivery.

Belting M, Wittrup A.

Methods Mol Biol. 2009;480:1-10. doi: 10.1007/978-1-59745-429-2_1. Review.

PMID:
19085127
12.

Characterizing peptide-mediated DNA internalization in human cancer cells.

Wittrup A, Belting M.

Methods Mol Biol. 2009;480:101-12. doi: 10.1007/978-1-59745-429-2_7.

PMID:
19085116
13.

Single chain fragment anti-heparan sulfate antibody targets the polyamine transport system and attenuates polyamine-dependent cell proliferation.

Welch JE, Bengtson P, Svensson K, Wittrup A, Jenniskens GJ, Ten Dam GB, Van Kuppevelt TH, Belting M.

Int J Oncol. 2008 Apr;32(4):749-56.

PMID:
18360702
14.

Identification of proteins released by mammalian cells that mediate DNA internalization through proteoglycan-dependent macropinocytosis.

Wittrup A, Sandgren S, Lilja J, Bratt C, Gustavsson N, Mörgelin M, Belting M.

J Biol Chem. 2007 Sep 21;282(38):27897-904. Epub 2007 Jul 10.

15.

N-terminal peptides from unprocessed prion proteins enter cells by macropinocytosis.

Magzoub M, Sandgren S, Lundberg P, Oglecka K, Lilja J, Wittrup A, Göran Eriksson LE, Langel U, Belting M, Gräslund A.

Biochem Biophys Res Commun. 2006 Sep 22;348(2):379-85. Epub 2006 Jul 24.

PMID:
16893522
16.

Nuclear delivery of macromolecules: barriers and carriers.

Belting M, Sandgren S, Wittrup A.

Adv Drug Deliv Rev. 2005 Feb 28;57(4):505-27. Epub 2004 Dec 28. Review.

PMID:
15722161
17.

The human antimicrobial peptide LL-37 transfers extracellular DNA plasmid to the nuclear compartment of mammalian cells via lipid rafts and proteoglycan-dependent endocytosis.

Sandgren S, Wittrup A, Cheng F, Jönsson M, Eklund E, Busch S, Belting M.

J Biol Chem. 2004 Apr 23;279(17):17951-6. Epub 2004 Feb 11.

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