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Plucked hair follicles from patients with chronic discoid lupus erythematosus show a disease-specific molecular signature.

Shalbaf M, Alase AA, Berekmeri A, Md Yusof MY, Pistolic J, Goodfield MJ, Edward S, Botchkareva NV, Stacey M, Vital EM, Wittmann M.

Lupus Sci Med. 2019 Jul 14;6(1):e000328. doi: 10.1136/lupus-2019-000328. eCollection 2019.


Baseline health status and setting impacted Minimal Clinically Important Differences in COPD: an explorative study.

Alma H, de Jong C, Jelusic D, Wittmann M, Schuler M, Kollen BJ, Sanderman R, Kocks J, Schultz K, der Molen TV.

J Clin Epidemiol. 2019 Jul 27. pii: S0895-4356(18)30992-2. doi: 10.1016/j.jclinepi.2019.07.015. [Epub ahead of print]


Evoked potentials as a translatable biomarker to track functional remyelination.

Farley BJ, Morozova E, Dion J, Wang B, Harvey BD, Gianni D, Wipke B, Cadavid D, Wittmann M, Hajos M.

Mol Cell Neurosci. 2019 Jul 26;99:103393. doi: 10.1016/j.mcn.2019.103393. [Epub ahead of print]


Thresholds for clinically important deterioration versus improvement in COPD health status: results from a randomised controlled trial in pulmonary rehabilitation and an observational study during routine clinical practice.

Alma HJ, de Jong C, Jelusic D, Wittmann M, Schuler M, Sanderman R, Schultz K, Kocks J, van der Molen T.

BMJ Open. 2019 Jun 28;9(6):e025776. doi: 10.1136/bmjopen-2018-025776.


Mindful Leader Development: How Leaders Experience the Effects of Mindfulness Training on Leader Capabilities.

Rupprecht S, Falke P, Kohls N, Tamdjidi C, Wittmann M, Kersemaekers W.

Front Psychol. 2019 May 15;10:1081. doi: 10.3389/fpsyg.2019.01081. eCollection 2019.


Antimicrobial Peptide LL-37 Facilitates Intracellular Uptake of RNA Aptamer Apt 21-2 Without Inducing an Inflammatory or Interferon Response.

Macleod T, Ward J, Alase AA, Bridgewood C, Wittmann M, Stonehouse NJ.

Front Immunol. 2019 Apr 24;10:857. doi: 10.3389/fimmu.2019.00857. eCollection 2019.


Meditation-Induced States, Vagal Tone, and Breathing Activity Are Related to Changes in Auditory Temporal Integration.

Linares Gutierrez D, Kübel S, Giersch A, Schmidt S, Meissner K, Wittmann M.

Behav Sci (Basel). 2019 May 7;9(5). pii: E51. doi: 10.3390/bs9050051.


Correction to: The IL-23p19/EBI3 heterodimeric cytokine termed IL-39 remains a theoretical cytokine in man.

Bridgewood C, Alase A, Watad A, Wittmann M, Cuthbert R, McGonagle D.

Inflamm Res. 2019 Jun;68(6):427. doi: 10.1007/s00011-019-01242-y.


The use of multi-criteria evaluation for the selection of study plots for monitoring of I. ricinus ticks - Example from Central Europe.

Švec P, Hönig V, Zubriková D, Wittmann M, Pfister K, Grubhoffer L.

Ticks Tick Borne Dis. 2019 Jun;10(4):905-910. doi: 10.1016/j.ttbdis.2019.04.014. Epub 2019 Apr 22.


Identification of myeloid cells in the human enthesis as the main source of local IL-23 production.

Bridgewood C, Watad A, Russell T, Palmer TM, Marzo-Ortega H, Khan A, Millner PA, Dunsmuir R, Rao A, Loughenbury P, Wittmann M, Cuthbert RJ, McGonagle DG.

Ann Rheum Dis. 2019 Jul;78(7):929-933. doi: 10.1136/annrheumdis-2018-214944. Epub 2019 Apr 24.


The suitability of liposomes for the delivery of hydrophobic drugs - A case study with curcumin.

Kolter M, Wittmann M, Köll-Weber M, Süss R.

Eur J Pharm Biopharm. 2019 Jul;140:20-28. doi: 10.1016/j.ejpb.2019.04.013. Epub 2019 Apr 20.


The IL-23p19/EBI3 heterodimeric cytokine termed IL-39 remains a theoretical cytokine in man.

Bridgewood C, Alase A, Watad A, Wittmann M, Cuthbert R, McGonagle D.

Inflamm Res. 2019 Jun;68(6):423-426. doi: 10.1007/s00011-019-01235-x. Epub 2019 Apr 13. Erratum in: Inflamm Res. 2019 May 7;:.


Model of Risk of Exposure to Lyme Borreliosis and Tick-Borne Encephalitis Virus-Infected Ticks in the Border Area of the Czech Republic (South Bohemia) and Germany (Lower Bavaria and Upper Palatinate).

Hönig V, Švec P, Marek L, Mrkvička T, Dana Z, Wittmann MV, Masař O, Szturcová D, Růžek D, Pfister K, Grubhoffer L.

Int J Environ Res Public Health. 2019 Apr 2;16(7). pii: E1173. doi: 10.3390/ijerph16071173.


Altered states of consciousness: With special reference to time and the self.

Wittmann M, Giersch A, Berkovich-Ohana A.

Psych J. 2019 Mar;8(1):5-7. doi: 10.1002/pchj.284. No abstract available.


Liberal transfusion strategy to prevent mortality and anaemia-associated, ischaemic events in elderly non-cardiac surgical patients - the study design of the LIBERAL-Trial.

Meybohm P, Lindau S, Treskatsch S, Francis R, Spies C, Velten M, Wittmann M, Gueresir E, Stoppe C, Kowark A, Coburn M, Selleng S, Baschin M, Jenichen G, Meersch M, Ermert T, Zarbock A, Kranke P, Kredel M, Helf A, Laufenberg-Feldmann R, Ferner M, Wittenmeier E, Gürtler KH, Kienbaum P, de Abreu MG, Sander M, Bauer M, Seyfried T, Gruenewald M, Choorapoikayil S, Mueller MM, Seifried E, Brosteanu O, Bogatsch H, Hasenclever D, Zacharowski K; LIBERAL Collaboration Group.

Trials. 2019 Feb 4;20(1):101. doi: 10.1186/s13063-019-3200-3.


Remote Meditation Support - A Multimodal Distant Intention Experiment.

Schmidt S, Jo HG, Wittmann M, Ambach W, Kübel S.

Explore (NY). 2018 Dec 28. pii: S1550-8307(18)30409-9. doi: 10.1016/j.explore.2018.12.002. [Epub ahead of print]


Genome-wide association study of myocardial infarction, atrial fibrillation, acute stroke, acute kidney injury and delirium after cardiac surgery - a sub-analysis of the RIPHeart-Study.

Westphal S, Stoppe C, Gruenewald M, Bein B, Renner J, Cremer J, Coburn M, Schaelte G, Boening A, Niemann B, Kletzin F, Roesner J, Strouhal U, Reyher C, Laufenberg-Feldmann R, Ferner M, Brandes IF, Bauer M, Kortgen A, Stehr SN, Wittmann M, Baumgarten G, Struck R, Meyer-Treschan T, Kienbaum P, Heringlake M, Schoen J, Sander M, Treskatsch S, Smul T, Wolwender E, Schilling T, Degenhardt F, Franke A, Mucha S, Tittmann L, Kohlhaas M, Fuernau G, Brosteanu O, Hasenclever D, Zacharowski K, Meybohm P; RIPHeart-Study Collaborators.

BMC Cardiovasc Disord. 2019 Jan 24;19(1):26. doi: 10.1186/s12872-019-1002-x.


The impact of disease-specific fears on outcome measures of pulmonary rehabilitation in patients with COPD.

Reijnders T, Schuler M, Wittmann M, Jelusic D, Troosters T, Janssens W, Stenzel NM, Schultz K, von Leupoldt A.

Respir Med. 2019 Jan;146:87-95. doi: 10.1016/j.rmed.2018.12.004. Epub 2018 Dec 13.


Time perception and impulsivity: A proposed relationship in addictive disorders.

Paasche C, Weibel S, Wittmann M, Lalanne L.

Neurosci Biobehav Rev. 2018 Dec 6. pii: S0149-7634(18)30034-4. doi: 10.1016/j.neubiorev.2018.12.006. [Epub ahead of print] Review.


Regression of Peripheral Subclinical Enthesopathy in Therapy-Naive Patients Treated With Ustekinumab for Moderate-to-Severe Chronic Plaque Psoriasis: A Fifty-Two-Week, Prospective, Open-Label Feasibility Study.

Savage L, Goodfield M, Horton L, Watad A, Hensor E, Emery P, Wakefield R, Wittmann M, McGonagle D.

Arthritis Rheumatol. 2019 Apr;71(4):626-631. doi: 10.1002/art.40778. Epub 2019 Mar 4.


Neural mechanisms for learning self and other ownership.

Lockwood PL, Wittmann MK, Apps MAJ, Klein-Flügge MC, Crockett MJ, Humphreys GW, Rushworth MFS.

Nat Commun. 2018 Nov 12;9(1):4747. doi: 10.1038/s41467-018-07231-9.


Dispositional orientation to the present and future and its role in pro-environmental behavior and sustainability.

Wittmann M, Sircova A.

Heliyon. 2018 Oct 26;4(10):e00882. doi: 10.1016/j.heliyon.2018.e00882. eCollection 2018 Oct. Review.


Phosphorylation of the neurogenic transcription factor SOX11 on serine 133 modulates neuronal morphogenesis.

Balta EA, Schäffner I, Wittmann MT, Sock E, von Zweydorf F, von Wittgenstein J, Steib K, Heim B, Kremmer E, Häberle BM, Ueffing M, Lie DC, Gloeckner CJ.

Sci Rep. 2018 Nov 1;8(1):16196. doi: 10.1038/s41598-018-34480-x.


Improve hip fracture outcome in the elderly patient (iHOPE): a study protocol for a pragmatic, multicentre randomised controlled trial to test the efficacy of spinal versus general anaesthesia.

Kowark A, Adam C, Ahrens J, Bajbouj M, Bollheimer C, Borowski M, Dodel R, Dolch M, Hachenberg T, Henzler D, Hildebrand F, Hilgers RD, Hoeft A, Isfort S, Kienbaum P, Knobe M, Knuefermann P, Kranke P, Laufenberg-Feldmann R, Nau C, Neuman MD, Olotu C, Rex C, Rossaint R, Sanders RD, Schmidt R, Schneider F, Siebert H, Skorning M, Spies C, Vicent O, Wappler F, Wirtz DC, Wittmann M, Zacharowski K, Zarbock A, Coburn M; iHOPE study group.

BMJ Open. 2018 Oct 18;8(10):e023609. doi: 10.1136/bmjopen-2018-023609.


Preoperative anemia and extensive transfusion during stay-in-hospital are critical for patient`s mortality: A retrospective multicenter cohort study of oncological patients undergoing radical cystectomy.

Ceanga AI, Ceanga M, Eveslage M, Herrmann E, Fischer D, Haferkamp A, Wittmann M, Müller S, Van Aken H, Steinbicker AU.

Transfus Apher Sci. 2018 Dec;57(6):739-745. doi: 10.1016/j.transci.2018.08.003. Epub 2018 Sep 5.


Publisher Correction: A novel two-score system for interferon status segregates autoimmune diseases and correlates with clinical features.

El-Sherbiny YM, Psarras A, Md Yusof MY, Hensor EMA, Tooze R, Doody G, Mohamed AAA, McGonagle D, Wittmann M, Emery P, Vital EM.

Sci Rep. 2018 Oct 1;8(1):14846. doi: 10.1038/s41598-018-33062-1.


Potent PDZ-Domain PICK1 Inhibitors that Modulate Amyloid Beta-Mediated Synaptic Dysfunction.

Lin EYS, Silvian LF, Marcotte DJ, Banos CC, Jow F, Chan TR, Arduini RM, Qian F, Baker DP, Bergeron C, Hession CA, Huganir RL, Borenstein CF, Enyedy I, Zou J, Rohde E, Wittmann M, Kumaravel G, Rhodes KJ, Scannevin RH, Dunah AW, Guckian KM.

Sci Rep. 2018 Sep 7;8(1):13438. doi: 10.1038/s41598-018-31680-3.


Tofacitinib for the treatment of psoriasis and psoriatic arthritis.

Berekmeri A, Mahmood F, Wittmann M, Helliwell P.

Expert Rev Clin Immunol. 2018 Sep;14(9):719-730. doi: 10.1080/1744666X.2018.1512404. Review.


Including changes in dyspnea after inpatient rehabilitation improves prediction models of exacerbations in COPD.

Schuler M, Wittmann M, Faller H, Schultz K.

Respir Med. 2018 Aug;141:87-93. doi: 10.1016/j.rmed.2018.06.027. Epub 2018 Jun 30.


The interrelations among aspects of dyspnea and symptoms of depression in COPD patients - a network analysis.

Schuler M, Wittmann M, Faller H, Schultz K.

J Affect Disord. 2018 Nov;240:33-40. doi: 10.1016/j.jad.2018.07.021. Epub 2018 Jul 23.


MK-7622: A First-in-Class M1 Positive Allosteric Modulator Development Candidate.

Beshore DC, N Di Marco C, Chang RK, Greshock TJ, Ma L, Wittmann M, Seager MA, Koeplinger KA, Thompson CD, Fuerst J, Hartman GD, Bilodeau MT, Ray WJ, Kuduk SD.

ACS Med Chem Lett. 2018 Apr 30;9(7):652-656. doi: 10.1021/acsmedchemlett.8b00095. eCollection 2018 Jul 12.


Phosphorylation Modulates the Subcellular Localization of SOX11.

Balta EA, Wittmann MT, Jung M, Sock E, Haeberle BM, Heim B, von Zweydorf F, Heppt J, von Wittgenstein J, Gloeckner CJ, Lie DC.

Front Mol Neurosci. 2018 Jun 19;11:211. doi: 10.3389/fnmol.2018.00211. eCollection 2018.


Assessing health status over time: impact of recall period and anchor question on the minimal clinically important difference of copd health status tools.

Alma HJ, de Jong C, Jelusic D, Wittmann M, Schuler M, Kollen BJ, Sanderman R, Schultz K, Kocks JWH, Van der Molen T.

Health Qual Life Outcomes. 2018 Jun 26;16(1):130. doi: 10.1186/s12955-018-0950-7.


Prediction of autoimmune connective tissue disease in an at-risk cohort: prognostic value of a novel two-score system for interferon status.

Md Yusof MY, Psarras A, El-Sherbiny YM, Hensor EMA, Dutton K, Ul-Hassan S, Zayat AS, Shalbaf M, Alase A, Wittmann M, Emery P, Vital EM.

Ann Rheum Dis. 2018 Oct;77(10):1432-1439. doi: 10.1136/annrheumdis-2018-213386. Epub 2018 Jun 21.


Ventral anterior cingulate cortex and social decision-making.

Lockwood PL, Wittmann MK.

Neurosci Biobehav Rev. 2018 Sep;92:187-191. doi: 10.1016/j.neubiorev.2018.05.030. Epub 2018 Jun 7. Review.


[Circadian rhythms and depression].

Wittmann M, Schreiber W, Landgrebe M, Hajak G.

Fortschr Neurol Psychiatr. 2018 May;86(5):308-318. doi: 10.1055/s-0043-123069. Epub 2018 May 29. Review. German.


Detection of IL-36γ through noninvasive tape stripping reliably discriminates psoriasis from atopic eczema.

Berekméri A, Latzko A, Alase A, Macleod T, Ainscough JS, Laws P, Goodfield M, Wright A, Helliwell P, Edward S, Brown GD, Reid DM, Wenzel J, Stacey M, Wittmann M.

J Allergy Clin Immunol. 2018 Sep;142(3):988-991.e4. doi: 10.1016/j.jaci.2018.04.031. Epub 2018 May 18. No abstract available.


Eco-Evolutionary Buffering: Rapid Evolution Facilitates Regional Species Coexistence despite Local Priority Effects.

Wittmann MJ, Fukami T.

Am Nat. 2018 Jun;191(6):E171-E184. doi: 10.1086/697187. Epub 2018 Mar 23.


[Patient perspective of the importance of asthma- and COPD-specific rehabilitation components: A secondary data analysis].

Lingner H, Schmidt K, Aumann-Suslin I, Wittmann M, Schuler M, Schultz K.

Z Evid Fortbild Qual Gesundhwes. 2018 Sep;135-136:41-49. doi: 10.1016/j.zefq.2018.03.008. Epub 2018 Apr 26. German.


A novel two-score system for interferon status segregates autoimmune diseases and correlates with clinical features.

El-Sherbiny YM, Psarras A, Md Yusof MY, Hensor EMA, Tooze R, Doody G, Mohamed AAA, McGonagle D, Wittmann M, Emery P, Vital EM.

Sci Rep. 2018 Apr 11;8(1):5793. doi: 10.1038/s41598-018-24198-1. Erratum in: Sci Rep. 2018 Oct 1;8(1):14846.


Exploring the maximum duration of the contingent negative variation.

Röhricht J, Jo HG, Wittmann M, Schmidt S.

Int J Psychophysiol. 2018 Jun;128:52-61. doi: 10.1016/j.ijpsycho.2018.03.020. Epub 2018 Mar 28.


Analysis of the expression pattern of the schizophrenia-risk and intellectual disability gene TCF4 in the developing and adult brain suggests a role in development and plasticity of cortical and hippocampal neurons.

Jung M, Häberle BM, Tschaikowsky T, Wittmann MT, Balta EA, Stadler VC, Zweier C, Dörfler A, Gloeckner CJ, Lie DC.

Mol Autism. 2018 Mar 22;9:20. doi: 10.1186/s13229-018-0200-1. eCollection 2018.


RIPHeart (Remote Ischemic Preconditioning for Heart Surgery) Study: Myocardial Dysfunction, Postoperative Neurocognitive Dysfunction, and 1 Year Follow-Up.

Meybohm P, Kohlhaas M, Stoppe C, Gruenewald M, Renner J, Bein B, Albrecht M, Cremer J, Coburn M, Schaelte G, Boening A, Niemann B, Sander M, Roesner J, Kletzin F, Mutlak H, Westphal S, Laufenberg-Feldmann R, Ferner M, Brandes IF, Bauer M, Stehr SN, Kortgen A, Wittmann M, Baumgarten G, Meyer-Treschan T, Kienbaum P, Heringlake M, Schoen J, Treskatsch S, Smul T, Wolwender E, Schilling T, Fuernau G, Bogatsch H, Brosteanu O, Hasenclever D, Zacharowski K; RIPHeart (Remote Ischemic Preconditioning for Heart Surgery) Study Collaborators.

J Am Heart Assoc. 2018 Mar 26;7(7). pii: e008077. doi: 10.1161/JAHA.117.008077.


Preclinical to Human Translational Pharmacology of the Novel M1 Positive Allosteric Modulator MK-7622.

Uslaner JM, Kuduk SD, Wittmann M, Lange HS, Fox SV, Min C, Pajkovic N, Harris D, Cilissen C, Mahon C, Mostoller K, Warrington S, Beshore DC.

J Pharmacol Exp Ther. 2018 Jun;365(3):556-566. doi: 10.1124/jpet.117.245894. Epub 2018 Mar 21.


Neural Mechanisms of Social Cognition in Primates.

Wittmann MK, Lockwood PL, Rushworth MFS.

Annu Rev Neurosci. 2018 Jul 8;41:99-118. doi: 10.1146/annurev-neuro-080317-061450. Epub 2018 Mar 21. Review.


A Workplace Mindfulness Intervention May Be Associated With Improved Psychological Well-Being and Productivity. A Preliminary Field Study in a Company Setting.

Kersemaekers W, Rupprecht S, Wittmann M, Tamdjidi C, Falke P, Donders R, Speckens A, Kohls N.

Front Psychol. 2018 Feb 28;9:195. doi: 10.3389/fpsyg.2018.00195. eCollection 2018.


Linking the Neuropsychiatric Disease Gene TCF4 to Neuronal Activity-Dependent Regulatory Networks.

Wittmann MT, Häberle BM.

J Neurosci. 2018 Mar 14;38(11):2653-2655. doi: 10.1523/JNEUROSCI.3475-17.2018. No abstract available.


IL-36γ Is a Strong Inducer of IL-23 in Psoriatic Cells and Activates Angiogenesis.

Bridgewood C, Fearnley GW, Berekmeri A, Laws P, Macleod T, Ponnambalam S, Stacey M, Graham A, Wittmann M.

Front Immunol. 2018 Feb 26;9:200. doi: 10.3389/fimmu.2018.00200. eCollection 2018.


Assessment of depression before and after inpatient rehabilitation in COPD patients: Psychometric properties of the German version of the Patient Health Questionnaire (PHQ-9/PHQ-2).

Schuler M, Strohmayer M, Mühlig S, Schwaighofer B, Wittmann M, Faller H, Schultz K.

J Affect Disord. 2018 May;232:268-275. doi: 10.1016/j.jad.2018.02.037. Epub 2018 Feb 21.


Inositol-Requiring Enzyme 1-Mediated Downregulation of MicroRNA (miR)-146a and miR-155 in Primary Dermal Fibroblasts across Three TNFRSF1A Mutations Results in Hyperresponsiveness to Lipopolysaccharide.

Harrison SR, Scambler T, Oubussad L, Wong C, Wittmann M, McDermott MF, Savic S.

Front Immunol. 2018 Feb 6;9:173. doi: 10.3389/fimmu.2018.00173. eCollection 2018.

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