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Items: 1 to 50 of 67

1.

NGS-Based genetic testing for heritable cardiovascular diseases. Specific requirements for obtaining informed consent.

Schmidtke J, Wittkowski K, Glaubitz R.

Mol Cell Probes. 2019 Jun;45:70-78. doi: 10.1016/j.mcp.2019.04.005. Epub 2019 May 3. Review.

PMID:
31059777
2.

Correction: Complex polymorphisms in endocytosis genes suggest alpha-cyclodextrin as a treatment for breast cancer.

Wittkowski KM, Dadurian C, Seybold MP, Kim HS, Hoshino A, Lyden D.

PLoS One. 2019 Mar 28;14(3):e0214826. doi: 10.1371/journal.pone.0214826. eCollection 2019.

3.

New Features for Measuring Disease Activity in Pediatric Localized Scleroderma.

Li SC, Li X, Pope E, Stewart K, Higgins GC, Rabinovich CE, O'Neil KM, Haines KA, Laxer RM, Punaro M, Jacobe H, Andrews T, Wittkowski K, Nyirenda T, Foeldvari I, Torok KS.

J Rheumatol. 2018 Dec;45(12):1680-1688. doi: 10.3899/jrheum.171381. Epub 2018 Sep 15.

PMID:
30219769
4.

Complex polymorphisms in endocytosis genes suggest alpha-cyclodextrin as a treatment for breast cancer.

Wittkowski KM, Dadurian C, Seybold MP, Kim HS, Hoshino A, Lyden D.

PLoS One. 2018 Jul 2;13(7):e0199012. doi: 10.1371/journal.pone.0199012. eCollection 2018. Erratum in: PLoS One. 2019 Mar 28;14(3):e0214826.

5.

A novel computational biostatistics approach implies impaired dephosphorylation of growth factor receptors as associated with severity of autism.

Wittkowski KM, Sonakya V, Bigio B, Tonn MK, Shic F, Ascano M, Nasca C, Gold-Von Simson G.

Transl Psychiatry. 2014 Jan 28;4:e354. doi: 10.1038/tp.2013.124.

6.

The Ontology of Clinical Research (OCRe): an informatics foundation for the science of clinical research.

Sim I, Tu SW, Carini S, Lehmann HP, Pollock BH, Peleg M, Wittkowski KM.

J Biomed Inform. 2014 Dec;52:78-91. doi: 10.1016/j.jbi.2013.11.002. Epub 2013 Nov 13.

7.

From single-SNP to wide-locus: genome-wide association studies identifying functionally related genes and intragenic regions in small sample studies.

Wittkowski KM, Sonakya V, Song T, Seybold MP, Keddache M, Durner M.

Pharmacogenomics. 2013 Mar;14(4):391-401. doi: 10.2217/pgs.13.28.

8.

Ontology-based federated data access to human studies information.

Sim I, Carini S, Tu SW, Detwiler LT, Brinkley J, Mollah SA, Burke K, Lehmann HP, Chakraborty S, Wittkowski KM, Pollock BH, Johnson TM, Huser V; Human Studies Database Project.

AMIA Annu Symp Proc. 2012;2012:856-65. Epub 2012 Nov 3.

9.

Clinical symptoms of skin, nails, and joints manifest independently in patients with concomitant psoriasis and psoriatic arthritis.

Wittkowski KM, Leonardi C, Gottlieb A, Menter A, Krueger GG, Tebbey PW, Belasco J, Soltani-Arabshahi R, Gray J, Horn L, Krueger JG; International Psoriasis Council.

PLoS One. 2011;6(6):e20279. doi: 10.1371/journal.pone.0020279. Epub 2011 Jun 1.

10.

Hyaluronidase and hyaluronan in insect venom allergy.

King TP, Wittkowski KM.

Int Arch Allergy Immunol. 2011;156(2):205-11. doi: 10.1159/000322847. Epub 2011 May 19.

PMID:
21597301
11.

The human studies database project: federating human studies design data using the ontology of clinical research.

Sim I, Carini S, Tu S, Wynden R, Pollock BH, Mollah SA, Gabriel D, Hagler HK, Scheuermann RH, Lehmann HP, Wittkowski KM, Nahm M, Bakken S.

Summit Transl Bioinform. 2010 Mar 1;2010:51-5.

12.

Evaluation metrics for biostatistical and epidemiological collaborations.

Rubio DM, Del Junco DJ, Bhore R, Lindsell CJ, Oster RA, Wittkowski KM, Welty LJ, Li YJ, Demets D; Biostatistics, Epidemiology, and Research Design (BERD) Key Function Committee of the Clinical and Translational Science Awards (CTSA) Consortium.

Stat Med. 2011 Oct 15;30(23):2767-77. doi: 10.1002/sim.4184. Epub 2011 Feb 1. Erratum in: Stat Med. 2012 Mar 15;31(6):600.

13.

Algal docosahexaenoic acid affects plasma lipoprotein particle size distribution in overweight and obese adults.

Neff LM, Culiner J, Cunningham-Rundles S, Seidman C, Meehan D, Maturi J, Wittkowski KM, Levine B, Breslow JL.

J Nutr. 2011 Feb;141(2):207-13. doi: 10.3945/jn.110.130021. Epub 2010 Dec 22.

14.

Nonparametric methods for molecular biology.

Wittkowski KM, Song T.

Methods Mol Biol. 2010;620:105-53. doi: 10.1007/978-1-60761-580-4_2.

15.

"Assessment of Multiple Ordinal Endpoints" by L. Häberle, A. Pfahlberg and O. Gefeller: biometrical journal (2009) 51, 217-226 article.

Wittkowski KM.

Biom J. 2009 Oct;51(5):870-1; author reply 872-3. doi: 10.1002/bimj.200900081. No abstract available.

PMID:
19771551
16.

In vitro and in vivo evidence that thrombospondin-1 (TSP-1) contributes to stirring- and shear-dependent activation of platelet-derived TGF-beta1.

Ahamed J, Janczak CA, Wittkowski KM, Coller BS.

PLoS One. 2009 Aug 12;4(8):e6608. doi: 10.1371/journal.pone.0006608.

17.

Atherosclerosis in survivors of Kawasaki disease.

Gupta-Malhotra M, Gruber D, Abraham SS, Roman MJ, Zabriskie JB, Hudgins LC, Flynn PA, Levine DM, Okorie U, Baday A, Schiller MS, Maturi J, Meehan D, Dyme J, Parker TS, Wittkowski KM, Gersony WM, Cooper RS.

J Pediatr. 2009 Oct;155(4):572-7. doi: 10.1016/j.jpeds.2009.04.054.

PMID:
19595365
18.
19.

An extension to a statistical approach for family based association studies provides insights into genetic risk factors for multiple sclerosis in the HLA-DRB1 gene.

Ramagopalan SV, McMahon R, Dyment DA, Sadovnick AD, Ebers GC, Wittkowski KM.

BMC Med Genet. 2009 Feb 4;10:10. doi: 10.1186/1471-2350-10-10.

20.

A modular analysis framework for blood genomics studies: application to systemic lupus erythematosus.

Chaussabel D, Quinn C, Shen J, Patel P, Glaser C, Baldwin N, Stichweh D, Blankenship D, Li L, Munagala I, Bennett L, Allantaz F, Mejias A, Ardura M, Kaizer E, Monnet L, Allman W, Randall H, Johnson D, Lanier A, Punaro M, Wittkowski KM, White P, Fay J, Klintmalm G, Ramilo O, Palucka AK, Banchereau J, Pascual V.

Immunity. 2008 Jul 18;29(1):150-64. doi: 10.1016/j.immuni.2008.05.012.

21.

U-Scores for Multivariate Data in Sports.

Wittkowski KM, Song T, Anderson K, Daniels JE.

J Quant Anal Sports. 2008 Jul 18;4(3). pii: 1129.

22.

Phenotyping genetic diseases using an extension of mu-scores for multivariate data.

Morales JF, Song T, Auerbach AD, Wittkowski KM.

Stat Appl Genet Mol Biol. 2008;7(1):Article 19. doi: 10.2202/1544-6115.1372. Epub 2008 Jun 30.

PMID:
18597665
23.

Analytical approaches to reporting long-term clinical trial data.

Papp KA, Fonjallaz P, Casset-Semanaz F, Krueger JG, Wittkowski KM.

Curr Med Res Opin. 2008 Jul;24(7):2001-8. doi: 10.1185/03007990802215315 . Epub 2008 Jun 4.

24.

Women's health measures in two North Carolina regions sampled from the Basic Automated Birth Yearbook (BABY) datasets: experimental findings, methodological limits and future directions.

Sills ES, Kling TM, Sills SS, Burns MJ, Carroll LP, Parker LD, Wittkowski KM.

Clin Exp Obstet Gynecol. 2008;35(1):27-31.

PMID:
18390076
25.

Identification of cellular pathways of "type 1," Th17 T cells, and TNF- and inducible nitric oxide synthase-producing dendritic cells in autoimmune inflammation through pharmacogenomic study of cyclosporine A in psoriasis.

Haider AS, Lowes MA, Suárez-Fariñas M, Zaba LC, Cardinale I, Khatcherian A, Novitskaya I, Wittkowski KM, Krueger JG.

J Immunol. 2008 Feb 1;180(3):1913-20.

26.

Diagnostic value of hepatocellular nodule vascularity after microbubble injection for characterizing malignancy in patients with cirrhosis.

Quaia E, D'Onofrio M, Cabassa P, Vecchiato F, Caffarri S, Pittiani F, Wittkowski KM, Cova MA.

AJR Am J Roentgenol. 2007 Dec;189(6):1474-83.

27.

Detecting artifacts on SNP chips.

Pellegrino M, Suárez-Fariñas M, Magnasco MO, Wittkowski KM.

Conf Proc IEEE Eng Med Biol Soc. 2006;1:4100-2.

PMID:
17947067
28.

Bioinformatics tools enabling u-statistics for microarrays.

Wittkowski KM, Haider A, Sehayek E, Suárez-Fariñas M, Pellegrino M, Peshansky A, Coffran C, Coker S.

Conf Proc IEEE Eng Med Biol Soc. 2006;1:3464-9.

29.

Interactions between estrogen effects and hunger effects in ovariectomized female mice. I. Measures of arousal.

Shelley DN, Dwyer E, Johnson C, Wittkowski KM, Pfaff DW.

Horm Behav. 2007 Nov;52(4):546-53. Epub 2007 Jul 26.

30.

Alefacept (anti-CD2) causes a selective reduction in circulating effector memory T cells (Tem) and relative preservation of central memory T cells (Tcm) in psoriasis.

Chamian F, Lin SL, Lee E, Kikuchi T, Gilleaudeau P, Sullivan-Whalen M, Cardinale I, Khatcherian A, Novitskaya I, Wittkowski KM, Krueger JG, Lowes MA.

J Transl Med. 2007 Jun 7;5:27.

31.

Gene expression patterns in blood leukocytes discriminate patients with acute infections.

Ramilo O, Allman W, Chung W, Mejias A, Ardura M, Glaser C, Wittkowski KM, Piqueras B, Banchereau J, Palucka AK, Chaussabel D.

Blood. 2007 Mar 1;109(5):2066-77. Epub 2006 Nov 14.

32.

Increase in TNF-alpha and inducible nitric oxide synthase-expressing dendritic cells in psoriasis and reduction with efalizumab (anti-CD11a).

Lowes MA, Chamian F, Abello MV, Fuentes-Duculan J, Lin SL, Nussbaum R, Novitskaya I, Carbonaro H, Cardinale I, Kikuchi T, Gilleaudeau P, Sullivan-Whalen M, Wittkowski KM, Papp K, Garovoy M, Dummer W, Steinman RM, Krueger JG.

Proc Natl Acad Sci U S A. 2005 Dec 27;102(52):19057-62.

33.

Harshlight: a "corrective make-up" program for microarray chips.

Suárez-Fariñas M, Pellegrino M, Wittkowski KM, Magnasco MO.

BMC Bioinformatics. 2005 Dec 10;6:294.

34.

"Harshlighting" small blemishes on microarrays.

Suárez-Fariñas M, Haider A, Wittkowski KM.

BMC Bioinformatics. 2005 Mar 22;6:65.

35.

Alefacept reduces infiltrating T cells, activated dendritic cells, and inflammatory genes in psoriasis vulgaris.

Chamian F, Lowes MA, Lin SL, Lee E, Kikuchi T, Gilleaudeau P, Sullivan-Whalen M, Cardinale I, Khatcherian A, Novitskaya I, Wittkowski KM, Krueger JG.

Proc Natl Acad Sci U S A. 2005 Feb 8;102(6):2075-80. Epub 2005 Jan 25.

36.

Effects and non-effects of paired identical observations in comparing proportions with binary matched-pairs data.

Wittkowski KM.

Stat Med. 2004 Jul 30;23(14):2317. No abstract available.

PMID:
15236433
37.

Expansion of melanoma-specific cytolytic CD8+ T cell precursors in patients with metastatic melanoma vaccinated with CD34+ progenitor-derived dendritic cells.

Paczesny S, Banchereau J, Wittkowski KM, Saracino G, Fay J, Palucka AK.

J Exp Med. 2004 Jun 7;199(11):1503-11. Epub 2004 Jun 1.

38.

Opiate-like effects of sugar on gene expression in reward areas of the rat brain.

Spangler R, Wittkowski KM, Goddard NL, Avena NM, Hoebel BG, Leibowitz SF.

Brain Res Mol Brain Res. 2004 May 19;124(2):134-42.

PMID:
15135221
39.

Combining several ordinal measures in clinical studies.

Wittkowski KM, Lee E, Nussbaum R, Chamian FN, Krueger JG.

Stat Med. 2004 May 30;23(10):1579-92.

PMID:
15122738
40.

Single injection of CD34+ progenitor-derived dendritic cell vaccine can lead to induction of T-cell immunity in patients with stage IV melanoma.

Palucka AK, Dhodapkar MV, Paczesny S, Burkeholder S, Wittkowski KM, Steinman RM, Fay J, Banchereau J.

J Immunother. 2003 Sep-Oct;26(5):432-9.

PMID:
12973032
41.
42.

A statistically valid alternative to the TDT.

Wittkowski KM, Liu X.

Hum Hered. 2002;54(3):157-64.

PMID:
12626848
43.

In silico quantitative trait locus map for atherosclerosis susceptibility in apolipoprotein E-deficient mice.

Smith JD, James D, Dansky HM, Wittkowski KM, Moore KJ, Breslow JL.

Arterioscler Thromb Vasc Biol. 2003 Jan 1;23(1):117-22.

PMID:
12524234
44.

Psoriasis as a model for T-cell-mediated disease: immunobiologic and clinical effects of treatment with multiple doses of efalizumab, an anti-CD11a antibody.

Gottlieb AB, Krueger JG, Wittkowski K, Dedrick R, Walicke PA, Garovoy M.

Arch Dermatol. 2002 May;138(5):591-600.

PMID:
12020219
45.

Comparison of centrifugation- and noncentrifugation-based techniques for recovery of motile human sperm in assisted reproduction.

Sills ES, Wittkowski KM, Tucker MJ, Perloe M, Kaplan CR, Palermo GD.

Arch Androl. 2002 Mar-Apr;48(2):141-5.

PMID:
11868627
46.

Effect on treatment outcome of coinfection with SEN viruses in patients with hepatitis C.

Rigas B, Hasan I, Rehman R, Donahue P, Wittkowski KM, Lebovics E.

Lancet. 2001 Dec 8;358(9297):1961-2.

PMID:
11747922
47.

Immune and clinical responses in patients with metastatic melanoma to CD34(+) progenitor-derived dendritic cell vaccine.

Banchereau J, Palucka AK, Dhodapkar M, Burkeholder S, Taquet N, Rolland A, Taquet S, Coquery S, Wittkowski KM, Bhardwaj N, Pineiro L, Steinman R, Fay J.

Cancer Res. 2001 Sep 1;61(17):6451-8.

48.
49.

Further thoughts about vaginal microbicide testing.

Wittkowski KM.

Am J Public Health. 2000 Jul;90(7):1155-6. No abstract available.

50.

Effects of administration of a single dose of a humanized monoclonal antibody to CD11a on the immunobiology and clinical activity of psoriasis.

Gottlieb A, Krueger JG, Bright R, Ling M, Lebwohl M, Kang S, Feldman S, Spellman M, Wittkowski K, Ochs HD, Jardieu P, Bauer R, White M, Dedrick R, Garovoy M.

J Am Acad Dermatol. 2000 Mar;42(3):428-35.

PMID:
10688712

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