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Items: 24


MicroRNA-deficient mouse embryonic stem cells acquire a functional interferon response.

Witteveldt J, Knol LI, Macias S.

Elife. 2019 Apr 23;8. pii: e44171. doi: 10.7554/eLife.44171.


Crosstalk Between Mammalian Antiviral Pathways.

Watson SF, Knol LI, Witteveldt J, Macias S.

Noncoding RNA. 2019 Mar 22;5(1). pii: E29. doi: 10.3390/ncrna5010029. Review.


Inhibition of Microprocessor Function during the Activation of the Type I Interferon Response.

Witteveldt J, Ivens A, Macias S.

Cell Rep. 2018 Jun 12;23(11):3275-3285. doi: 10.1016/j.celrep.2018.05.049.


Comparison of Next-Generation Sequencing Technologies for Comprehensive Assessment of Full-Length Hepatitis C Viral Genomes.

Thomson E, Ip CL, Badhan A, Christiansen MT, Adamson W, Ansari MA, Bibby D, Breuer J, Brown A, Bowden R, Bryant J, Bonsall D, Da Silva Filipe A, Hinds C, Hudson E, Klenerman P, Lythgow K, Mbisa JL, McLauchlan J, Myers R, Piazza P, Roy S, Trebes A, Sreenu VB, Witteveldt J; STOP-HCV Consortium, Barnes E, Simmonds P.

J Clin Microbiol. 2016 Oct;54(10):2470-84. doi: 10.1128/JCM.00330-16. Epub 2016 Jul 6.


The influence of CpG and UpA dinucleotide frequencies on RNA virus replication and characterization of the innate cellular pathways underlying virus attenuation and enhanced replication.

Atkinson NJ, Witteveldt J, Evans DJ, Simmonds P.

Nucleic Acids Res. 2014 Apr;42(7):4527-45. doi: 10.1093/nar/gku075. Epub 2014 Jan 26.


The influence of viral RNA secondary structure on interactions with innate host cell defences.

Witteveldt J, Blundell R, Maarleveld JJ, McFadden N, Evans DJ, Simmonds P.

Nucleic Acids Res. 2014 Mar;42(5):3314-29. doi: 10.1093/nar/gkt1291. Epub 2013 Dec 13.


Influence of genome-scale RNA structure disruption on the replication of murine norovirus--similar replication kinetics in cell culture but attenuation of viral fitness in vivo.

McFadden N, Arias A, Dry I, Bailey D, Witteveldt J, Evans DJ, Goodfellow I, Simmonds P.

Nucleic Acids Res. 2013 Jul;41(12):6316-31. doi: 10.1093/nar/gkt334. Epub 2013 Apr 29.


Development and assay of RNA transcripts of enterovirus species A to D, rhinovirus species a to C, and human parechovirus: assessment of assay sensitivity and specificity of real-time screening and typing methods.

McLeish NJ, Witteveldt J, Clasper L, McIntyre C, McWilliam Leitch EC, Hardie A, Bennett S, Gunson R, Carman WF, Feeney SA, Coyle PV, Vipond B, Muir P, Benschop K, Wolthers K, Waris M, Osterback R, Johannessen I, Templeton K, Harvala H, Simmonds P.

J Clin Microbiol. 2012 Sep;50(9):2910-7. doi: 10.1128/JCM.01172-12. Epub 2012 Jun 27.


Rapid simultaneous detection of enterovirus and parechovirus RNAs in clinical samples by one-step real-time reverse transcription-PCR assay.

Bennett S, Harvala H, Witteveldt J, McWilliam Leitch EC, McLeish N, Templeton K, Gunson R, Carman WF, Simmonds P.

J Clin Microbiol. 2011 Jul;49(7):2620-4. doi: 10.1128/JCM.02445-10. Epub 2011 May 18.


Mutations within a conserved region of the hepatitis C virus E2 glycoprotein that influence virus-receptor interactions and sensitivity to neutralizing antibodies.

Dhillon S, Witteveldt J, Gatherer D, Owsianka AM, Zeisel MB, Zahid MN, Rychłowska M, Foung SK, Baumert TF, Angus AG, Patel AH.

J Virol. 2010 Jun;84(11):5494-507. doi: 10.1128/JVI.02153-09. Epub 2010 Mar 17.


A reporter cell line for rapid and sensitive evaluation of hepatitis C virus infectivity and replication.

Iro M, Witteveldt J, Angus AG, Woerz I, Kaul A, Bartenschlager R, Patel AH.

Antiviral Res. 2009 Aug;83(2):148-55. doi: 10.1016/j.antiviral.2009.04.007. Epub 2009 May 3.


Mutations in hepatitis C virus E2 located outside the CD81 binding sites lead to escape from broadly neutralizing antibodies but compromise virus infectivity.

Keck ZY, Li SH, Xia J, von Hahn T, Balfe P, McKeating JA, Witteveldt J, Patel AH, Alter H, Rice CM, Foung SK.

J Virol. 2009 Jun;83(12):6149-60. doi: 10.1128/JVI.00248-09. Epub 2009 Mar 25.


CD81 is dispensable for hepatitis C virus cell-to-cell transmission in hepatoma cells.

Witteveldt J, Evans MJ, Bitzegeio J, Koutsoudakis G, Owsianka AM, Angus AG, Keck ZY, Foung SK, Pietschmann T, Rice CM, Patel AH.

J Gen Virol. 2009 Jan;90(Pt 1):48-58. doi: 10.1099/vir.0.006700-0.


Broadly neutralizing human monoclonal antibodies to the hepatitis C virus E2 glycoprotein.

Owsianka AM, Tarr AW, Keck ZY, Li TK, Witteveldt J, Adair R, Foung SK, Ball JK, Patel AH.

J Gen Virol. 2008 Mar;89(Pt 3):653-9. doi: 10.1099/vir.0.83386-0.


Inactivation of White Spot Syndrome Virus (WSSV) by normal rabbit serum: implications for the role of the envelope protein VP28 in WSSV infection of shrimp.

Robalino J, Payne C, Parnell P, Shepard E, Grimes AC, Metz A, Prior S, Witteveldt J, Vlak JM, Gross PS, Warr G, Browdy CL.

Virus Res. 2006 Jun;118(1-2):55-61. Epub 2006 Jan 18.


Nucleocapsid protein VP15 is the basic DNA binding protein of white spot syndrome virus of shrimp.

Witteveldt J, Vermeesch AM, Langenhof M, de Lang A, Vlak JM, van Hulten MC.

Arch Virol. 2005 Jun;150(6):1121-33. Epub 2005 Feb 10.


Protection of Penaeus monodon against white spot syndrome virus using a WSSV subunit vaccine.

Witteveldt J, Vlak JM, van Hulten MC.

Fish Shellfish Immunol. 2004 May;16(5):571-9.


Protection of Penaeus monodon against white spot syndrome virus by oral vaccination.

Witteveldt J, Cifuentes CC, Vlak JM, van Hulten MC.

J Virol. 2004 Feb;78(4):2057-61.


Identification and phylogeny of a non-specific endonuclease gene of white spot syndrome virus of shrimp.

Witteveldt J, Van Hulten MC, Vlak JM.

Virus Genes. 2001 Dec;23(3):331-7.


The white spot syndrome virus DNA genome sequence.

van Hulten MC, Witteveldt J, Peters S, Kloosterboer N, Tarchini R, Fiers M, Sandbrink H, Lankhorst RK, Vlak JM.

Virology. 2001 Jul 20;286(1):7-22.


White spot syndrome virus envelope protein VP28 is involved in the systemic infection of shrimp.

van Hulten MC, Witteveldt J, Snippe M, Vlak JM.

Virology. 2001 Jul 5;285(2):228-33.


Phylogeny of the arthropod endosymbiont Wolbachia based on the wsp gene.

Van Meer MM, Witteveldt J, Stouthamer R.

Insect Mol Biol. 1999 Aug;8(3):399-408.


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