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Items: 36

1.

The Intracellular Cyclophilin PpiB Contributes to the Virulence of Staphylococcus aureus Independently of Its Peptidyl-Prolyl cis/trans Isomerase Activity.

Keogh RA, Zapf RL, Wiemels RE, Wittekind MA, Carroll RK.

Infect Immun. 2018 Oct 25;86(11). pii: e00379-18. doi: 10.1128/IAI.00379-18. Print 2018 Nov.

2.

Native Human Monoclonal Antibodies with Potent Cross-Lineage Neutralization of Influenza B Viruses.

Vigil A, Estélles A, Kauvar LM, Johnson SK, Tripp RA, Wittekind M.

Antimicrob Agents Chemother. 2018 Apr 26;62(5). pii: e02269-17. doi: 10.1128/AAC.02269-17. Print 2018 May.

3.

Bacteriophage Lysin CF-301, a Potent Antistaphylococcal Biofilm Agent.

Schuch R, Khan BK, Raz A, Rotolo JA, Wittekind M.

Antimicrob Agents Chemother. 2017 Jun 27;61(7). pii: e02666-16. doi: 10.1128/AAC.02666-16. Print 2017 Jul.

4.

Cell wall hydrolases and antibiotics: exploiting synergy to create efficacious new antimicrobial treatments.

Wittekind M, Schuch R.

Curr Opin Microbiol. 2016 Oct;33:18-24. doi: 10.1016/j.mib.2016.05.006. Epub 2016 May 31. Review.

PMID:
27257994
5.

Measurements of Monoclonal Antibody Self-Association Are Correlated with Complex Biophysical Properties.

Geng SB, Wittekind M, Vigil A, Tessier PM.

Mol Pharm. 2016 May 2;13(5):1636-45. doi: 10.1021/acs.molpharmaceut.6b00071. Epub 2016 Apr 19.

PMID:
27045771
6.

Combination therapy with lysin CF-301 and antibiotic is superior to antibiotic alone for treating methicillin-resistant Staphylococcus aureus-induced murine bacteremia.

Schuch R, Lee HM, Schneider BC, Sauve KL, Law C, Khan BK, Rotolo JA, Horiuchi Y, Couto DE, Raz A, Fischetti VA, Huang DB, Nowinski RC, Wittekind M.

J Infect Dis. 2014 May 1;209(9):1469-78. doi: 10.1093/infdis/jit637. Epub 2013 Nov 28.

7.

Enhancing antibody Fc heterodimer formation through electrostatic steering effects: applications to bispecific molecules and monovalent IgG.

Gunasekaran K, Pentony M, Shen M, Garrett L, Forte C, Woodward A, Ng SB, Born T, Retter M, Manchulenko K, Sweet H, Foltz IN, Wittekind M, Yan W.

J Biol Chem. 2010 Jun 18;285(25):19637-46. doi: 10.1074/jbc.M110.117382. Epub 2010 Apr 16.

8.

A diversity of antibody epitopes can induce signaling through the erythropoietin receptor.

Lim AC, Ketchem RR, Borges L, Carabeo T, Carter J, Hoover JE, Hu Z, Wittekind M, Zhou H, Mehlin C.

Biochemistry. 2010 May 11;49(18):3797-804. doi: 10.1021/bi1001147.

PMID:
20337434
9.

X-ray crystal structures of human immunodeficiency virus type 1 protease mutants complexed with atazanavir.

Klei HE, Kish K, Lin PF, Guo Q, Friborg J, Rose RE, Zhang Y, Goldfarb V, Langley DR, Wittekind M, Sheriff S.

J Virol. 2007 Sep;81(17):9525-35. Epub 2007 May 30.

10.

The structure of Dasatinib (BMS-354825) bound to activated ABL kinase domain elucidates its inhibitory activity against imatinib-resistant ABL mutants.

Tokarski JS, Newitt JA, Chang CY, Cheng JD, Wittekind M, Kiefer SE, Kish K, Lee FY, Borzillerri R, Lombardo LJ, Xie D, Zhang Y, Klei HE.

Cancer Res. 2006 Jun 1;66(11):5790-7.

11.

Comparative studies of active site-ligand interactions among various recombinant constructs of human beta-amyloid precursor protein cleaving enzyme.

Kopcho LM, Ma J, Marcinkeviciene J, Lai Z, Witmer MR, Cheng J, Yanchunas J, Tredup J, Corbett M, Calambur D, Wittekind M, Paruchuri M, Kothari D, Lee G, Ganguly S, Ramamurthy V, Morin PE, Camac DM, King RW, Lasut AL, Ross OH, Hillman MC, Fish B, Shen K, Dowling RL, Kim YB, Graciani NR, Collins D, Combs AP, George H, Thompson LA, Copeland RA.

Arch Biochem Biophys. 2003 Feb 15;410(2):307-16.

PMID:
12573291
12.

High prevalence of K-ras-2 mutations in hepatocellular carcinomas in workers exposed to vinyl chloride.

Weihrauch M, Benick M, Lehner G, Wittekind M, Bader M, Wrbitzk R, Tannapfel A.

Int Arch Occup Environ Health. 2001 Aug;74(6):405-10.

PMID:
11563603
13.

Backbone and side chain dynamics of uncomplexed human adipocyte and muscle fatty acid-binding proteins.

Constantine KL, Friedrichs MS, Wittekind M, Jamil H, Chu CH, Parker RA, Goldfarb V, Mueller L, Farmer BT 2nd.

Biochemistry. 1998 Jun 2;37(22):7965-80.

PMID:
9609689
14.

Characterization of NADP+ binding to perdeuterated MurB: backbone atom NMR assignments and chemical-shift changes.

Constantine KL, Mueller L, Goldfarb V, Wittekind M, Metzler WJ, Yanchunas J Jr, Robertson JG, Malley MF, Friedrichs MS, Farmer BT 2nd.

J Mol Biol. 1997 Apr 18;267(5):1223-46.

PMID:
9150408
15.
16.

Localizing the NADP+ binding site on the MurB enzyme by NMR.

Farmer BT 2nd, Constantine KL, Goldfarb V, Friedrichs MS, Wittekind M, Yanchunas J Jr, Robertson JG, Mueller L.

Nat Struct Biol. 1996 Dec;3(12):995-7. No abstract available.

PMID:
8946851
17.

Orientation of peptide fragments from Sos proteins bound to the N-terminal SH3 domain of Grb2 determined by NMR spectroscopy.

Wittekind M, Mapelli C, Farmer BT 2nd, Suen KL, Goldfarb V, Tsao J, Lavoie T, Barbacid M, Meyers CA, Mueller L.

Biochemistry. 1994 Nov 22;33(46):13531-9.

PMID:
7947763
18.

Sequential 1H, 13C, and 15N NMR assignments and solution conformation of apokedarcidin.

Constantine KL, Colson KL, Wittekind M, Friedrichs MS, Zein N, Tuttle J, Langley DR, Leet JE, Schroeder DR, Lam KS, et al.

Biochemistry. 1994 Sep 27;33(38):11438-52.

PMID:
7918358
19.

An automated procedure for the assignment of protein 1HN, 15N, 13C alpha, 1H alpha, 13C beta and 1H beta resonances.

Friedrichs MS, Mueller L, Wittekind M.

J Biomol NMR. 1994 Sep;4(5):703-26.

PMID:
7919955
20.

Solution structure of an isolated antibody VL domain.

Constantine KL, Friedrichs MS, Metzler WJ, Wittekind M, Hensley P, Mueller L.

J Mol Biol. 1994 Feb 11;236(1):310-27.

PMID:
8107112
21.

Production and characterization of an antibody Fv fragment 15N-labeled in the VL domain only.

Goldfarb V, Wittekind M, Jeffrey PD, Mueller L, Constantine KL.

J Mol Biol. 1993 Jul 5;232(1):15-22.

PMID:
8331656
22.

Aliphatic 1H and 13C resonance assignments for the 26-10 antibody VL domain derived from heteronuclear multidimensional NMR spectroscopy.

Constantine KL, Goldfarb V, Wittekind M, Friedrichs MS, Anthony J, Ng SC, Mueller L.

J Biomol NMR. 1993 Jan;3(1):41-54.

PMID:
8448434
23.

Solution structure of the phosphocarrier protein HPr from Bacillus subtilis by two-dimensional NMR spectroscopy.

Wittekind M, Rajagopal P, Branchini BR, Reizer J, Saier MH Jr, Klevit RE.

Protein Sci. 1992 Oct;1(10):1363-76.

24.

Production of stable anti-digoxin Fv in Escherichia coli.

Anthony J, Near R, Wong SL, Iida E, Ernst E, Wittekind M, Haber E, Ng SC.

Mol Immunol. 1992 Oct;29(10):1237-47.

PMID:
1528194
25.

Interaction of the RNA-binding domain of the hnRNP C proteins with RNA.

Görlach M, Wittekind M, Beckman RA, Mueller L, Dreyfuss G.

EMBO J. 1992 Sep;11(9):3289-95.

26.

1H, 13C, and 15N NMR assignments and global folding pattern of the RNA-binding domain of the human hnRNP C proteins.

Wittekind M, Görlach M, Friedrichs M, Dreyfuss G, Mueller L.

Biochemistry. 1992 Jul 14;31(27):6254-65.

PMID:
1385725
27.

Sequential 1H and 15N NMR assignments and secondary structure of a recombinant anti-digoxin antibody VL domain.

Constantine KL, Goldfarb V, Wittekind M, Anthony J, Ng SC, Mueller L.

Biochemistry. 1992 Jun 2;31(21):5033-43.

PMID:
1318076
28.

A refocused and optimized HNCA: increased sensitivity and resolution in large macromolecules.

Farmer BT 2nd, Venters RA, Spicer LD, Wittekind MG, Müller L.

J Biomol NMR. 1992 Mar;2(2):195-202.

PMID:
1422152
29.
30.
31.

Common structural changes accompany the functional inactivation of HPr by seryl phosphorylation or by serine to aspartate substitution.

Wittekind M, Reizer J, Deutscher J, Saier MH, Klevit RE.

Biochemistry. 1989 Dec 26;28(26):9908-12.

PMID:
2515891
32.

The structure of HPr and site-directed mutagenesis.

Waygood EB, Sharma S, Bhanot P, el-Kabbani OA, Delbaere LT, Georges F, Wittekind MG, Klevit RE.

FEMS Microbiol Rev. 1989 Jun;5(1-2):43-52. Review. No abstract available.

PMID:
2483820
33.

The secY-rpmJ region of the spc ribosomal protein operon in Escherichia coli: structural alterations affecting secY expression.

Ueguchi C, Wittekind M, Nomura M, Akiyama Y, Ito K.

Mol Gen Genet. 1989 May;217(1):1-5.

PMID:
2671645
34.
35.
36.

A temperature-sensitive mutant of E. coli exhibiting slow processing of exported proteins.

Ito K, Wittekind M, Nomura M, Shiba K, Yura T, Miura A, Nashimoto H.

Cell. 1983 Mar;32(3):789-97.

PMID:
6339072

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