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Cell cycle-dependent and -independent telomere shortening accompanies murine brain aging.

Ain Q, Schmeer C, Penndorf D, Fischer M, Bondeva T, Förster M, Haenold R, Witte OW, Kretz A.

Aging (Albany NY). 2018 Nov 20;10(11):3397-3420. doi: 10.18632/aging.101655.


Interferon-γ Receptor 1 and GluR1 upregulated in motor neurons of symptomatic hSOD1G93A mice.

Sengupta S, Le TT, Adam A, Tadić V, Stubendorff B, Keiner S, Kloss L, Prell T, Witte OW, Grosskreutz J.

Eur J Neurosci. 2018 Nov 20. doi: 10.1111/ejn.14276. [Epub ahead of print]


[How many potential organ donors are there really? : Retrospective analysis of why determination of irreversible loss of brain function was not performed in deceased patients with relevant brain damage].

Brauer M, Günther A, Pleul K, Götze M, Wachsmuth C, Meinig T, Bauer M, Witte OW, Rahmel A.

Anaesthesist. 2018 Nov 16. doi: 10.1007/s00101-018-0510-x. [Epub ahead of print] German.


Phenotypic and functional differences between senescent and aged murine microglia.

Stojiljkovic MR, Ain Q, Bondeva T, Heller R, Schmeer C, Witte OW.

Neurobiol Aging. 2018 Oct 12;74:56-69. doi: 10.1016/j.neurobiolaging.2018.10.007. [Epub ahead of print]


In Older Patients Treated for Dizziness and Vertigo in Multimodal Rehabilitation Somatic Deficits Prevail While Anxiety Plays a Minor Role Compared to Young and Middle Aged Patients.

Dietzek M, Finn S, Karvouniari P, Zeller MA, Klingner CM, Guntinas-Lichius O, Witte OW, Axer H.

Front Aging Neurosci. 2018 Oct 30;10:345. doi: 10.3389/fnagi.2018.00345. eCollection 2018.


Acute Stroke Treatment by Surgical Recanalization of Extracranial Internal Carotid Artery Occlusion: A Single Center Experience.

Schubert J, Witte OW, Settmacher U, Mayer TE, Günther A, Zanow J, Klingner CM.

Vasc Endovascular Surg. 2018 Oct 9:1538574418800131. doi: 10.1177/1538574418800131. [Epub ahead of print]


The impact of motor impairment on the processing of sensory information.

Klingner CM, Brodoehl S, Witte OW, Guntinas-Lichius O, Volk GF.

Behav Brain Res. 2018 Sep 21. pii: S0166-4328(18)30863-5. doi: 10.1016/j.bbr.2018.09.016. [Epub ahead of print]


Dual Task Effects on Visual Attention Capacity in Normal Aging.

Künstler ECS, Penning MD, Napiórkowski N, Klingner CM, Witte OW, Müller HJ, Bublak P, Finke K.

Front Psychol. 2018 Sep 3;9:1564. doi: 10.3389/fpsyg.2018.01564. eCollection 2018.


Weather, Weather Changes and the Risk of Bell's Palsy: A Multicenter Case-Crossover Study.

Franzke P, Bitsch A, Walther M, Schiffner R, Rupprecht S, Rasche M, Volk GF, Witte OW, Schlattmann P, Guntinas-Lichius O, Hagemann G, Schwab M, Rakers F.

Neuroepidemiology. 2018;51(3-4):207-215. doi: 10.1159/000492671. Epub 2018 Sep 11.


Sepsis-associated encephalopathy.

Helbing DL, Böhm L, Witte OW.

CMAJ. 2018 Sep 10;190(36):E1083. doi: 10.1503/cmaj.180454. No abstract available.


B-cell depletion is ineffective in a patient with granulomatous optic neuropathy.

Wagner F, Radbruch H, Witte OW, Geis C.

Neurol Neuroimmunol Neuroinflamm. 2018 Aug 10;5(5):e493. doi: 10.1212/NXI.0000000000000493. eCollection 2018 Sep. No abstract available.


Effects of Temporary Functional Deafferentation in Chronic Stroke Patients: Who Profits More?

Sens E, Franz M, Preul C, Meissner W, Witte OW, Miltner WHR, Weiss T.

Neural Plast. 2018 Jul 29;2018:7392024. doi: 10.1155/2018/7392024. eCollection 2018.


Enhancement of face-sensitive ERPs in older adults induced by face recognition training.

Limbach K, Kaufmann JM, Wiese H, Witte OW, Schweinberger SR.

Neuropsychologia. 2018 Oct;119:197-213. doi: 10.1016/j.neuropsychologia.2018.08.010. Epub 2018 Aug 13.


Ultrasonography of the Vagus Nerve in Parkinson's Disease.

Fedtke N, Witte OW, Prell T.

Front Neurol. 2018 Jul 2;9:525. doi: 10.3389/fneur.2018.00525. eCollection 2018.


Not your average Saturday night palsy-High resolution nerve ultrasound resolves rare cause of wrist drop.

Heiling B, Waschke A, Ceanga M, Grimm A, Witte OW, Axer H.

Clin Neurol Neurosurg. 2018 Sep;172:160-161. doi: 10.1016/j.clineuro.2018.07.006. Epub 2018 Jul 9.


The Use of Ostrich Eggs for In Ovo Research: Making Preclinical Imaging Research Affordable and Available.

Freesmeyer M, Kuehnel C, Opfermann T, Niksch T, Wiegand S, Stolz R, Huonker R, Witte OW, Winkens T.

J Nucl Med. 2018 Dec;59(12):1901-1906. doi: 10.2967/jnumed.118.210310. Epub 2018 Jun 22.


Impact of transcranial direct current stimulation on structural plasticity of the somatosensory system.

Hirtz R, Weiss T, Huonker R, Witte OW.

J Neurosci Res. 2018 Aug;96(8):1367-1379. doi: 10.1002/jnr.24258. Epub 2018 Jun 6.


Impact of transcranial direct current stimulation on somatosensory transfer learning: When the secondary somatosensory cortex comes into play.

Hirtz R, Weiss T, Huonker R, Witte OW.

Brain Res. 2018 Jun 15;1689:98-108. doi: 10.1016/j.brainres.2018.03.031. Epub 2018 Apr 3.


Dysregulation of chemokine receptor expression and function in leukocytes from ALS patients.

Perner C, Perner F, Stubendorff B, Förster M, Witte OW, Heidel FH, Prell T, Grosskreutz J.

J Neuroinflammation. 2018 Mar 28;15(1):99. doi: 10.1186/s12974-018-1135-3.


DNA plasticity and damage in amyotrophic lateral sclerosis.

Penndorf D, Witte OW, Kretz A.

Neural Regen Res. 2018 Feb;13(2):173-180. doi: 10.4103/1673-5374.226377. Review.


Frataxin overexpression in Müller cells protects retinal ganglion cells in a mouse model of ischemia/reperfusion injury in vivo.

Schultz R, Krug M, Precht M, Wohl SG, Witte OW, Schmeer C.

Sci Rep. 2018 Mar 19;8(1):4846. doi: 10.1038/s41598-018-22887-5.


Management of therapeutic anticoagulation in patients with intracerebral haemorrhage and mechanical heart valves.

Kuramatsu JB, Sembill JA, Gerner ST, Sprügel MI, Hagen M, Roeder SS, Endres M, Haeusler KG, Sobesky J, Schurig J, Zweynert S, Bauer M, Vajkoczy P, Ringleb PA, Purrucker J, Rizos T, Volkmann J, Müllges W, Kraft P, Schubert AL, Erbguth F, Nueckel M, Schellinger PD, Glahn J, Knappe UJ, Fink GR, Dohmen C, Stetefeld H, Fisse AL, Minnerup J, Hagemann G, Rakers F, Reichmann H, Schneider H, Wöpking S, Ludolph AC, Stösser S, Neugebauer H, Röther J, Michels P, Schwarz M, Reimann G, Bäzner H, Schwert H, Claßen J, Michalski D, Grau A, Palm F, Urbanek C, Wöhrle JC, Alshammari F, Horn M, Bahner D, Witte OW, Günther A, Hamann GF, Lücking H, Dörfler A, Achenbach S, Schwab S, Huttner HB.

Eur Heart J. 2018 May 14;39(19):1709-1723. doi: 10.1093/eurheartj/ehy056.


Universal characteristics of evolution and development are inherent in fetal autonomic brain maturation.

Schmidt A, Schukat-Talamazzini EG, Zöllkau J, Pytlik A, Leibl S, Kumm K, Bode F, Kynass I, Witte OW, Schleussner E, Schneider U, Hoyer D.

Auton Neurosci. 2018 Jul;212:32-41. doi: 10.1016/j.autneu.2018.02.004. Epub 2018 Mar 5.


Somatosensory deficits.

Klingner CM, Witte OW.

Handb Clin Neurol. 2018;151:185-206. doi: 10.1016/B978-0-444-63622-5.00009-7. Review.


Value of the eazyplex® CSF direct assay in rapid diagnosis of invasive meningococcal disease - Case report.

Karrasch M, Eisenach S, Vogel U, Zinke J, Witte OW, Günther A, Romeike B, Rödel J.

Acta Microbiol Immunol Hung. 2018 Aug 1;65(3):309-315. doi: 10.1556/030.65.2018.021. Epub 2018 Mar 7.


Rapid increases in nitrogen oxides are associated with acute myocardial infarction: A case-crossover study.

Rasche M, Walther M, Schiffner R, Kroegel N, Rupprecht S, Schlattmann P, Schulze PC, Franzke P, Witte OW, Schwab M, Rakers F.

Eur J Prev Cardiol. 2018 Nov;25(16):1707-1716. doi: 10.1177/2047487318755804. Epub 2018 Feb 15.


Transcriptomic alterations during ageing reflect the shift from cancer to degenerative diseases in the elderly.

Aramillo Irizar P, Schäuble S, Esser D, Groth M, Frahm C, Priebe S, Baumgart M, Hartmann N, Marthandan S, Menzel U, Müller J, Schmidt S, Ast V, Caliebe A, König R, Krawczak M, Ristow M, Schuster S, Cellerino A, Diekmann S, Englert C, Hemmerich P, Sühnel J, Guthke R, Witte OW, Platzer M, Ruppin E, Kaleta C.

Nat Commun. 2018 Jan 30;9(1):327. doi: 10.1038/s41467-017-02395-2.


Impact of chronic maternal stress during early gestation on maternal-fetal stress transfer and fetal stress sensitivity in sheep.

Dreiling M, Schiffner R, Bischoff S, Rupprecht S, Kroegel N, Schubert H, Witte OW, Schwab M, Rakers F.

Stress. 2018 Jan;21(1):1-10. doi: 10.1080/10253890.2017.1387534. Epub 2017 Oct 18.


Tissue-, sex-, and age-specific DNA methylation of rat glucocorticoid receptor gene promoter and insulin-like growth factor 2 imprinting control region.

Agba OB, Lausser L, Huse K, Bergmeier C, Jahn N, Groth M, Bens M, Sahm A, Gall M, Witte OW, Kestler HA, Schwab M, Platzer M.

Physiol Genomics. 2017 Nov 1;49(11):690-702. doi: 10.1152/physiolgenomics.00009.2017. Epub 2017 Sep 15.


Adult hippocampal neurogenesis poststroke: More new granule cells but aberrant morphology and impaired spatial memory.

Woitke F, Ceanga M, Rudolph M, Niv F, Witte OW, Redecker C, Kunze A, Keiner S.

PLoS One. 2017 Sep 14;12(9):e0183463. doi: 10.1371/journal.pone.0183463. eCollection 2017.


Automatic affective responses towards the bed in patients with primary insomnia: evidence for a negativity bias.

Koranyi N, Meinhard M, Bublak P, Witte OW, Rupprecht S.

J Sleep Res. 2018 Apr;27(2):215-219. doi: 10.1111/jsr.12591. Epub 2017 Aug 22.


DNA strand breaks and TDP-43 mislocation are absent in the murine hSOD1G93A model of amyotrophic lateral sclerosis in vivo and in vitro.

Penndorf D, Tadić V, Witte OW, Grosskreutz J, Kretz A.

PLoS One. 2017 Aug 23;12(8):e0183684. doi: 10.1371/journal.pone.0183684. eCollection 2017.


Fetal Sheep Mesenteric Resistance Arteries: Functional and Structural Maturation.

Müller JJ, Schwab M, Rosenfeld CR, Antonow-Schlorke I, Nathanielsz PW, Rakers F, Schubert H, Witte OW, Rupprecht S.

J Vasc Res. 2017;54(5):259-271. doi: 10.1159/000477629. Epub 2017 Aug 16.


Transfer of Patients in a Telestroke Network: What Are the Relevant Factors for Making This Decision?

Klingner CM, Brodoehl S, Funck L, Klingner CC, Berrouschot J, Witte OW, Günther A.

Telemed J E Health. 2018 Feb;24(2):116-120. doi: 10.1089/tmj.2017.0087. Epub 2017 Jul 27.


Sigma 1 receptor activation modifies intracellular calcium exchange in the G93AhSOD1 ALS model.

Tadić V, Malci A, Goldhammer N, Stubendorff B, Sengupta S, Prell T, Keiner S, Liu J, Guenther M, Frahm C, Witte OW, Grosskreutz J.

Neuroscience. 2017 Sep 17;359:105-118. doi: 10.1016/j.neuroscience.2017.07.012. Epub 2017 Jul 16.


Bilateral vestibulopathy with positive Tullio phenomenon.

Finn S, Dietzek M, Karvouniari P, Klingner CM, Neumann R, Guntinas-Lichius O, Witte OW, Axer H.

Laryngoscope. 2018 May;128(5):1223-1225. doi: 10.1002/lary.26690. Epub 2017 May 31.


Neurofilament markers for ALS correlate with extent of upper and lower motor neuron disease.

Poesen K, De Schaepdryver M, Stubendorff B, Gille B, Muckova P, Wendler S, Prell T, Ringer TM, Rhode H, Stevens O, Claeys KG, Couwelier G, D'Hondt A, Lamaire N, Tilkin P, Van Reijen D, Gourmaud S, Fedtke N, Heiling B, Rumpel M, Rödiger A, Gunkel A, Witte OW, Paquet C, Vandenberghe R, Grosskreutz J, Van Damme P.

Neurology. 2017 Jun 13;88(24):2302-2309. doi: 10.1212/WNL.0000000000004029. Epub 2017 May 12.


Weather as a risk factor for epileptic seizures: A case-crossover study.

Rakers F, Walther M, Schiffner R, Rupprecht S, Rasche M, Kockler M, Witte OW, Schlattmann P, Schwab M.

Epilepsia. 2017 Jul;58(7):1287-1295. doi: 10.1111/epi.13776. Epub 2017 May 8.


The Influence of Eye Closure on Somatosensory Discrimination: A Trade-off Between Simple Perception and Discrimination.

Götz T, Hanke D, Huonker R, Weiss T, Klingner C, Brodoehl S, Baumbach P, Witte OW.

Cereb Cortex. 2017 Jun 1;27(6):3231-3239. doi: 10.1093/cercor/bhx089.


Impact of sleep disordered breathing on short-term post-operative outcome after elective coronary artery bypass graft surgery: a prospective observational study.

Rupprecht S, Schultze T, Nachtmann A, Rastan AJ, Doenst T, Schwab M, Witte OW, Rohe S, Zwacka I, Hoyer H.

Eur Respir J. 2017 Apr 5;49(4). pii: 1601486. doi: 10.1183/13993003.01486-2016. Print 2017 Apr.


GABAergic Transmission during Brain Development: Multiple Effects at Multiple Stages.

Kirmse K, Hübner CA, Isbrandt D, Witte OW, Holthoff K.

Neuroscientist. 2018 Feb;24(1):36-53. doi: 10.1177/1073858417701382. Epub 2017 Apr 5.


Inpatient treatment of patients with acute idiopathic peripheral facial palsy: A population-based healthcare research study.

Plumbaum K, Volk GF, Boeger D, Buentzel J, Esser D, Steinbrecher A, Hoffmann K, Jecker P, Mueller A, Radtke G, Witte OW, Guntinas-Lichius O.

Clin Otolaryngol. 2017 Dec;42(6):1267-1274. doi: 10.1111/coa.12862. Epub 2017 Apr 2.


Effect of skilled reaching training and enriched environment on generation of oligodendrocytes in the adult sensorimotor cortex and corpus callosum.

Keiner S, Niv F, Neumann S, Steinbach T, Schmeer C, Hornung K, Schlenker Y, Förster M, Witte OW, Redecker C.

BMC Neurosci. 2017 Mar 9;18(1):31. doi: 10.1186/s12868-017-0347-2.


Transfer of maternal psychosocial stress to the fetus.

Rakers F, Rupprecht S, Dreiling M, Bergmeier C, Witte OW, Schwab M.

Neurosci Biobehav Rev. 2017 Feb 22. pii: S0149-7634(16)30719-9. doi: 10.1016/j.neubiorev.2017.02.019. [Epub ahead of print] Review.


Monitoring fetal maturation-objectives, techniques and indices of autonomic function.

Hoyer D, Żebrowski J, Cysarz D, Gonçalves H, Pytlik A, Amorim-Costa C, Bernardes J, Ayres-de-Campos D, Witte OW, Schleußner E, Stroux L, Redman C, Georgieva A, Payne S, Clifford G, Signorini MG, Magenes G, Andreotti F, Malberg H, Zaunseder S, Lakhno I, Schneider U.

Physiol Meas. 2017 May;38(5):R61-R88. doi: 10.1088/1361-6579/aa5fca. Epub 2017 Feb 10. Review.


Transcriptional profiling reveals protective mechanisms in brains of long-lived mice.

Frahm C, Srivastava A, Schmidt S, Mueller J, Groth M, Guenther M, Ji Y, Priebe S, Platzer M, Witte OW.

Neurobiol Aging. 2017 Apr;52:23-31. doi: 10.1016/j.neurobiolaging.2016.12.016. Epub 2016 Dec 27.


The Processing of Somatosensory Information Shifts from an Early Parallel into a Serial Processing Mode: A Combined fMRI/MEG Study.

Klingner CM, Brodoehl S, Huonker R, Witte OW.

Front Syst Neurosci. 2016 Dec 20;10:103. doi: 10.3389/fnsys.2016.00103. eCollection 2016.


Clinical Presentation, Magnetic Resonance Angiography, Ultrasound Findings, and Stroke Patterns in Patients with Vertebral Artery Dissection.

Günther A, Witte OW, Freesmeyer M, Drescher R.

Eur Neurol. 2016;76(5-6):284-294. Epub 2016 Nov 1.


The Effect of Spinal Tap Test on Different Sensory Modalities of Postural Stability in Idiopathic Normal Pressure Hydrocephalus.

Abram K, Bohne S, Bublak P, Karvouniari P, Klingner CM, Witte OW, Guntinas-Lichius O, Axer H.

Dement Geriatr Cogn Dis Extra. 2016 Sep 27;6(3):447-457. eCollection 2016 Sep-Dec.


Vertigo and the processing of vestibular information: A review in the context of predictive coding.

Klingner CM, Axer H, Brodoehl S, Witte OW.

Neurosci Biobehav Rev. 2016 Dec;71:379-387. doi: 10.1016/j.neubiorev.2016.09.009. Epub 2016 Sep 14. Review.


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