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Items: 1 to 50 of 957

1.

Applying the D50 disease progression model to gray and white matter pathology in amyotrophic lateral sclerosis.

Steinbach R, Batyrbekova M, Gaur N, Voss A, Stubendorff B, Mayer TE, Gaser C, Witte OW, Prell T, Grosskreutz J.

Neuroimage Clin. 2019 Nov 28;25:102094. doi: 10.1016/j.nicl.2019.102094. [Epub ahead of print]

2.

A genetically defined disease model reveals that urothelial cells can initiate divergent bladder cancer phenotypes.

Wang L, Smith BA, Balanis NG, Tsai BL, Nguyen K, Cheng MW, Obusan MB, Esedebe FN, Patel SJ, Zhang H, Clark PM, Sisk AE, Said JW, Huang J, Graeber TG, Witte ON, Chin AI, Park JW.

Proc Natl Acad Sci U S A. 2020 Jan 7;117(1):563-572. doi: 10.1073/pnas.1915770117. Epub 2019 Dec 23.

3.

Early Stroke Induces Long-Term Impairment of Adult Neurogenesis Accompanied by Hippocampal-Mediated Cognitive Decline.

Kathner-Schaffert C, Karapetow L, Günther M, Rudolph M, Dahab M, Baum E, Lehmann T, Witte OW, Redecker C, Schmeer CW, Keiner S.

Cells. 2019 Dec 17;8(12). pii: E1654. doi: 10.3390/cells8121654.

4.

Targeting cellular heterogeneity with CXCR2 blockade for the treatment of therapy-resistant prostate cancer.

Li Y, He Y, Butler W, Xu L, Chang Y, Lei K, Zhang H, Zhou Y, Gao AC, Zhang Q, Taylor DG, Cheng D, Farber-Katz S, Karam R, Landrith T, Li B, Wu S, Hsuan V, Yang Q, Hu H, Chen X, Flowers M, McCall SJ, Lee JK, Smith BA, Park JW, Goldstein AS, Witte ON, Wang Q, Rettig MB, Armstrong AJ, Cheng Q, Huang J.

Sci Transl Med. 2019 Dec 4;11(521). pii: eaax0428. doi: 10.1126/scitranslmed.aax0428.

PMID:
31801883
5.

Amitosenescence and Pseudomitosenescence: Putative New Players in the Aging Process.

Wengerodt D, Schmeer C, Witte OW, Kretz A.

Cells. 2019 Nov 29;8(12). pii: E1546. doi: 10.3390/cells8121546.

6.

Optimized photo-stimulation of halorhodopsin for long-term neuronal inhibition.

Zhang C, Yang S, Flossmann T, Gao S, Witte OW, Nagel G, Holthoff K, Kirmse K.

BMC Biol. 2019 Nov 27;17(1):95. doi: 10.1186/s12915-019-0717-6.

7.

Dissecting Aging and Senescence-Current Concepts and Open Lessons.

Schmeer C, Kretz A, Wengerodt D, Stojiljkovic M, Witte OW.

Cells. 2019 Nov 15;8(11). pii: E1446. doi: 10.3390/cells8111446. Review.

8.

An 82-Year-Old Man With Sleep-Onset Insomnia, Breathing Arrest, and Heart Failure.

de la Motte T, Schwab M, Schultze T, Witte OW, Rupprecht S.

Chest. 2019 Nov;156(5):e95-e98. doi: 10.1016/j.chest.2019.05.044.

PMID:
31699235
9.

Acute Encephalopathy and Cardiac Arrest Induced by Intrathecal Gadolinium Administration.

Besteher B, Chung HY, Mayer TE, Witte OW, Kirchhof K, Schwab M.

Clin Neuroradiol. 2019 Nov 2. doi: 10.1007/s00062-019-00845-6. [Epub ahead of print] No abstract available.

PMID:
31679044
10.

18F-FAC PET visualizes brain-infiltrating leukocytes in a mouse model of multiple sclerosis.

Chen BY, Ghezzi C, Villegas B, Quon A, Radu CG, Witte ON, Clark PM.

J Nucl Med. 2019 Oct 25. pii: jnumed.119.229351. doi: 10.2967/jnumed.119.229351. [Epub ahead of print]

PMID:
31653711
11.

Measuring Anxiety in Older Adults: Development, Diagnostic Accuracy, and Preliminary Validation of a Short-Form of the German Geriatric Anxiety Scale (GAS-G-SF).

Gottschling J, Dörendahl J, Prell T, Karbach J, Bunz M, Kindermann I, Moussaoui J, Spinath FM, Wedegärtner S, Witte OW, Greiff S, Segal DL.

J Pers Assess. 2019 Oct 18:1-9. doi: 10.1080/00223891.2019.1677679. [Epub ahead of print]

PMID:
31625412
12.

Conserved aging-related signatures of senescence and inflammation in different tissues and species.

Barth E, Srivastava A, Stojiljkovic M, Frahm C, Axer H, Witte OW, Marz M.

Aging (Albany NY). 2019 Oct 12;11(19):8556-8572. doi: 10.18632/aging.102345. Epub 2019 Oct 12.

13.

Association of Surgical Hematoma Evacuation vs Conservative Treatment With Functional Outcome in Patients With Cerebellar Intracerebral Hemorrhage.

Kuramatsu JB, Biffi A, Gerner ST, Sembill JA, Sprügel MI, Leasure A, Sansing L, Matouk C, Falcone GJ, Endres M, Haeusler KG, Sobesky J, Schurig J, Zweynert S, Bauer M, Vajkoczy P, Ringleb PA, Purrucker J, Rizos T, Volkmann J, Müllges W, Kraft P, Schubert AL, Erbguth F, Nueckel M, Schellinger PD, Glahn J, Knappe UJ, Fink GR, Dohmen C, Stetefeld H, Fisse AL, Minnerup J, Hagemann G, Rakers F, Reichmann H, Schneider H, Rahmig J, Ludolph AC, Stösser S, Neugebauer H, Röther J, Michels P, Schwarz M, Reimann G, Bäzner H, Schwert H, Claßen J, Michalski D, Grau A, Palm F, Urbanek C, Wöhrle JC, Alshammari F, Horn M, Bahner D, Witte OW, Günther A, Hamann GF, Hagen M, Roeder SS, Lücking H, Dörfler A, Testai FD, Woo D, Schwab S, Sheth KN, Huttner HB.

JAMA. 2019 Oct 8;322(14):1392-1403. doi: 10.1001/jama.2019.13014.

PMID:
31593272
14.

Automated objective and marker-free facial grading using photographs of patients with facial palsy.

Mothes O, Modersohn L, Volk GF, Klingner C, Witte OW, Schlattmann P, Denzler J, Guntinas-Lichius O.

Eur Arch Otorhinolaryngol. 2019 Dec;276(12):3335-3343. doi: 10.1007/s00405-019-05647-7. Epub 2019 Sep 18.

PMID:
31535292
15.

The importance of different learning stages for motor sequence learning after stroke.

Dahms C, Brodoehl S, Witte OW, Klingner CM.

Hum Brain Mapp. 2020 Jan;41(1):270-286. doi: 10.1002/hbm.24793. Epub 2019 Sep 14. Review.

PMID:
31520506
16.

Development of Hematopoietic Stem Cell-Engineered Invariant Natural Killer T Cell Therapy for Cancer.

Zhu Y, Smith DJ, Zhou Y, Li YR, Yu J, Lee D, Wang YC, Di Biase S, Wang X, Hardoy C, Ku J, Tsao T, Lin LJ, Pham AT, Moon H, McLaughlin J, Cheng D, Hollis RP, Campo-Fernandez B, Urbinati F, Wei L, Pang L, Rezek V, Berent-Maoz B, Macabali MH, Gjertson D, Wang X, Galic Z, Kitchen SG, An DS, Hu-Lieskovan S, Kaplan-Lefko PJ, De Oliveira SN, Seet CS, Larson SM, Forman SJ, Heath JR, Zack JA, Crooks GM, Radu CG, Ribas A, Kohn DB, Witte ON, Yang L.

Cell Stem Cell. 2019 Oct 3;25(4):542-557.e9. doi: 10.1016/j.stem.2019.08.004. Epub 2019 Sep 5.

PMID:
31495780
17.

Sensitive Detection and Analysis of Neoantigen-Specific T Cell Populations from Tumors and Blood.

Peng S, Zaretsky JM, Ng AHC, Chour W, Bethune MT, Choi J, Hsu A, Holman E, Ding X, Guo K, Kim J, Xu AM, Heath JE, Noh WJ, Zhou J, Su Y, Lu Y, McLaughlin J, Cheng D, Witte ON, Baltimore D, Ribas A, Heath JR.

Cell Rep. 2019 Sep 3;28(10):2728-2738.e7. doi: 10.1016/j.celrep.2019.07.106.

18.

Maternal psychosocial stress during early gestation impairs fetal structural brain development in sheep.

Hermes M, Antonow-Schlorke I, Hollstein D, Kuehnel S, Rakers F, Frauendorf V, Dreiling M, Rupprecht S, Schubert H, Witte OW, Schwab M.

Stress. 2019 Aug 30:1-10. doi: 10.1080/10253890.2019.1652266. [Epub ahead of print]

PMID:
31469022
19.

[Intensive care aspects of autoimmune encephalitis].

Günther A, Schubert J, Witte OW, Brämer D.

Med Klin Intensivmed Notfmed. 2019 Oct;114(7):620-627. doi: 10.1007/s00063-019-0604-5. Epub 2019 Aug 27. Review. German.

PMID:
31456008
20.

Changes in Oral Microbial Ecology of C57BL/6 Mice at Different Ages Associated with Sampling Methodology.

Hernández-Arriaga A, Baumann A, Witte OW, Frahm C, Bergheim I, Camarinha-Silva A.

Microorganisms. 2019 Aug 22;7(9). pii: E283. doi: 10.3390/microorganisms7090283.

21.

Poor emotional well-being is associated with rapid progression in amyotrophic lateral sclerosis.

Prell T, Steinbach R, Witte OW, Grosskreutz J.

eNeurologicalSci. 2019 Jul 18;16:100198. doi: 10.1016/j.ensci.2019.100198. eCollection 2019 Sep.

22.

Gastric dysmotility in Parkinson's disease is not caused by alterations of the gastric pacemaker cells.

Heimrich KG, Jacob VYP, Schaller D, Stallmach A, Witte OW, Prell T.

NPJ Parkinsons Dis. 2019 Jul 26;5:15. doi: 10.1038/s41531-019-0087-3. eCollection 2019.

23.

Data on adherence to medication in neurological patients using the German Stendal Adherence to Medication Score (SAMS).

Prell T, Grosskreutz J, Mendorf S, Witte OW, Kunze A.

Data Brief. 2019 Mar 19;23:103855. doi: 10.1016/j.dib.2019.103855. eCollection 2019 Apr.

24.

The Effect of Endovascular Thrombectomy Studies on the Decision to Transfer Patients in a Telestroke Network.

Klingner C, Tinschert P, Brodoehl S, Berrouschot J, Witte OW, Günther A, Klingner CM.

Telemed J E Health. 2019 Jul 19. doi: 10.1089/tmj.2019.0067. [Epub ahead of print]

PMID:
31329520
25.

Cognitive deficits have only limited influence on health-related quality of life in amyotrophic lateral sclerosis.

Prell T, Witte OW, Gunkel A, Grosskreutz J.

Aging Ment Health. 2019 Jul 18:1-5. doi: 10.1080/13607863.2019.1642296. [Epub ahead of print]

PMID:
31317778
26.

Pan-cancer Convergence to a Small-Cell Neuroendocrine Phenotype that Shares Susceptibilities with Hematological Malignancies.

Balanis NG, Sheu KM, Esedebe FN, Patel SJ, Smith BA, Park JW, Alhani S, Gomperts BN, Huang J, Witte ON, Graeber TG.

Cancer Cell. 2019 Jul 8;36(1):17-34.e7. doi: 10.1016/j.ccell.2019.06.005.

PMID:
31287989
27.

Publisher Correction: Transcriptomic alterations during ageing reflect the shift from cancer to degenerative diseases in the elderly.

Irizar PA, Schäuble S, Esser D, Groth M, Frahm C, Priebe S, Baumgart M, Hartmann N, Marthandan S, Menzel U, Müller J, Schmidt S, Ast V, Caliebe A, König R, Krawczak M, Ristow M, Schuster S, Cellerino A, Diekmann S, Englert C, Hemmerich P, Sühnel J, Guthke R, Witte OW, Platzer M, Ruppin E, Kaleta C.

Nat Commun. 2019 May 31;10(1):2459. doi: 10.1038/s41467-019-10559-5.

28.

Autoimmune encephalitis with anti-IgLON5 and anti-GABAB-receptor antibodies: A case report.

Chung HY, Wickel J, Voss A, Ceanga M, Sell J, Witte OW, Geis C.

Medicine (Baltimore). 2019 May;98(20):e15706. doi: 10.1097/MD.0000000000015706.

29.

Association Between Systemic Inflammation, Carotid Arteriosclerosis, and Autonomic Dysfunction.

Rupprecht S, Finn S, Hoyer D, Guenther A, Witte OW, Schultze T, Schwab M.

Transl Stroke Res. 2020 Feb;11(1):50-59. doi: 10.1007/s12975-019-00706-x. Epub 2019 May 16.

PMID:
31093927
30.

Characteristics in Non-Vitamin K Antagonist Oral Anticoagulant-Related Intracerebral Hemorrhage.

Gerner ST, Kuramatsu JB, Sembill JA, Sprügel MI, Hagen M, Knappe RU, Endres M, Haeusler KG, Sobesky J, Schurig J, Zweynert S, Bauer M, Vajkoczy P, Ringleb PA, Purrucker JC, Rizos T, Volkmann J, Müllges W, Kraft P, Schubert AL, Erbguth F, Nueckel M, Schellinger PD, Glahn J, Knappe UJ, Fink GR, Dohmen C, Stetefeld H, Fisse AL, Minnerup J, Hagemann G, Rakers F, Reichmann H, Schneider H, Rahmig J, Ludolph AC, Stösser S, Neugebauer H, Röther J, Michels P, Schwarz M, Reimann G, Bäzner H, Schwert H, Claßen J, Michalski D, Grau A, Palm F, Urbanek C, Wöhrle JC, Alshammari F, Horn M, Bahner D, Witte OW, Günther A, Hamann GF, Engelhorn T, Lücking H, Dörfler A, Schwab S, Huttner HB.

Stroke. 2019 Jun;50(6):1392-1402. doi: 10.1161/STROKEAHA.118.023492. Epub 2019 May 16.

PMID:
31092170
31.

Divide or Commit - Revisiting the Role of Cell Cycle Regulators in Adult Hippocampal Neurogenesis.

Urbach A, Witte OW.

Front Cell Dev Biol. 2019 Apr 24;7:55. doi: 10.3389/fcell.2019.00055. eCollection 2019. Review.

32.

Plasma VCAM1 levels correlate with disease severity in Parkinson's disease.

Perner C, Perner F, Gaur N, Zimmermann S, Witte OW, Heidel FH, Grosskreutz J, Prell T.

J Neuroinflammation. 2019 May 8;16(1):94. doi: 10.1186/s12974-019-1482-8.

33.

Heparin for prophylaxis of venous thromboembolism in intracerebral haemorrhage.

Sprügel MI, Sembill JA, Kuramatsu JB, Gerner ST, Hagen M, Roeder SS, Endres M, Haeusler KG, Sobesky J, Schurig J, Zweynert S, Bauer M, Vajkoczy P, Ringleb PA, Purrucker JC, Rizos T, Volkmann J, Muellges W, Kraft P, Schubert AL, Erbguth F, Nueckel M, Schellinger PD, Glahn J, Knappe UJ, Fink GR, Dohmen C, Stetefeld H, Fisse AL, Minnerup J, Hagemann G, Rakers F, Reichmann H, Schneider H, Wöpking S, Ludolph AC, Stösser S, Neugebauer H, Röther J, Michels P, Schwarz M, Reimann G, Bäzner H, Schwert H, Classen J, Michalski D, Grau A, Palm F, Urbanek C, Wöhrle JC, Alshammari F, Horn M, Bahner D, Witte OW, Guenther A, Hamann GF, Lücking H, Dörfler A, Schwab S, Huttner HB.

J Neurol Neurosurg Psychiatry. 2019 Jul;90(7):783-791. doi: 10.1136/jnnp-2018-319786. Epub 2019 Apr 16.

PMID:
30992334
34.

Propentdyopents as Heme Degradation Intermediates Constrict Mouse Cerebral Arterioles and Are Present in the Cerebrospinal Fluid of Patients With Subarachnoid Hemorrhage.

Joerk A, Ritter M, Langguth N, Seidel RA, Freitag D, Herrmann KH, Schaefgen A, Ritter M, Günther M, Sommer C, Braemer D, Walter J, Ewald C, Kalff R, Reichenbach JR, Westerhausen M, Pohnert G, Witte OW, Holthoff K.

Circ Res. 2019 Jun 7;124(12):e101-e114. doi: 10.1161/CIRCRESAHA.118.314160. Epub 2019 Apr 5.

PMID:
30947629
35.

Cause or effect: Altered brain and network activity in cervical dystonia is partially normalized by botulinum toxin treatment.

Brodoehl S, Wagner F, Prell T, Klingner C, Witte OW, Günther A.

Neuroimage Clin. 2019;22:101792. doi: 10.1016/j.nicl.2019.101792. Epub 2019 Mar 26.

36.

[Preoperative conditioning in ageing patients-gerontosurgery].

Tautenhahn HM, Witte OW, Settmacher U.

Chirurg. 2019 Jul;90(7):524-528. doi: 10.1007/s00104-019-0941-1. Review. German.

PMID:
30919018
37.

Biomarkers for Dementia, Fatigue, and Depression in Parkinson's Disease.

Prell T, Witte OW, Grosskreutz J.

Front Neurol. 2019 Mar 8;10:195. doi: 10.3389/fneur.2019.00195. eCollection 2019. Review.

38.

Somatostatin Interneurons Promote Neuronal Synchrony in the Neonatal Hippocampus.

Flossmann T, Kaas T, Rahmati V, Kiebel SJ, Witte OW, Holthoff K, Kirmse K.

Cell Rep. 2019 Mar 19;26(12):3173-3182.e5. doi: 10.1016/j.celrep.2019.02.061.

39.

To rout or snort in the sleepe: a detailed medical description of sleep disordered breathing and its consequences by Georg Grau in 1688.

Rupprecht S, Schönefeld D, Kroegel N, Witte OW, Schwab M, Paditz E.

Eur Respir J. 2019 May 9;53(5). pii: 1801799. doi: 10.1183/13993003.01799-2018. Print 2019 May. No abstract available.

PMID:
30846473
40.

MEK-ERK signaling is a therapeutic target in metastatic castration resistant prostate cancer.

Nickols NG, Nazarian R, Zhao SG, Tan V, Uzunangelov V, Xia Z, Baertsch R, Neeman E, Gao AC, Thomas GV, Howard L, De Hoedt AM, Stuart J, Goldstein T, Chi K, Gleave ME, Graff JN, Beer TM, Drake JM, Evans CP, Aggarwal R, Foye A, Feng FY, Small EJ, Aronson WJ, Freedland SJ, Witte ON, Huang J, Alumkal JJ, Reiter RE, Rettig MB.

Prostate Cancer Prostatic Dis. 2019 Dec;22(4):531-538. doi: 10.1038/s41391-019-0134-5. Epub 2019 Feb 25.

41.

Clusters of non-adherence to medication in neurological patients.

Prell T, Grosskreutz J, Mendorf S, Franke GH, Witte OW, Kunze A.

Res Social Adm Pharm. 2019 Dec;15(12):1419-1424. doi: 10.1016/j.sapharm.2019.01.001. Epub 2019 Feb 11.

PMID:
30772239
42.

Reaction to Endoplasmic Reticulum Stress via ATF6 in Amyotrophic Lateral Sclerosis Deteriorates With Aging.

Prell T, Stubendorff B, Le TT, Gaur N, Tadić V, Rödiger A, Witte OW, Grosskreutz J.

Front Aging Neurosci. 2019 Jan 25;11:5. doi: 10.3389/fnagi.2019.00005. eCollection 2019.

43.

T cell antigen discovery via trogocytosis.

Li G, Bethune MT, Wong S, Joglekar AV, Leonard MT, Wang JK, Kim JT, Cheng D, Peng S, Zaretsky JM, Su Y, Luo Y, Heath JR, Ribas A, Witte ON, Baltimore D.

Nat Methods. 2019 Feb;16(2):183-190. doi: 10.1038/s41592-018-0305-7. Epub 2019 Jan 28.

44.

Comparison of anonymous versus nonanonymous responses to a medication adherence questionnaire in patients with Parkinson's disease.

Prell T, Schaller D, Perner C, Franke GH, Witte OW, Kunze A, Grosskreutz J.

Patient Prefer Adherence. 2019 Jan 18;13:151-155. doi: 10.2147/PPA.S186732. eCollection 2019.

45.

Neurosurgical device implantation for neuro-oncological patients: What to avoid? Technical note.

Chaskis E, Sadeghi N, De Witte O, Lefranc F.

World Neurosurg. 2019 Jan 23. pii: S1878-8750(19)30130-5. doi: 10.1016/j.wneu.2019.01.035. [Epub ahead of print]

46.

Very Low Frequency Heart Rate Variability Predicts the Development of Post-Stroke Infections.

Brämer D, Günther A, Rupprecht S, Nowack S, Adam J, Meyer F, Schwab M, Surber R, Witte OW, Hoyer H, Hoyer D.

Transl Stroke Res. 2019 Dec;10(6):607-619. doi: 10.1007/s12975-018-0684-1. Epub 2019 Jan 7.

PMID:
30617993
47.

Stroke Accelerates and Uncouples Intrinsic and Synaptic Excitability Maturation of Mouse Hippocampal DCX+ Adult-Born Granule Cells.

Ceanga M, Keiner S, Grünewald B, Haselmann H, Frahm C, Couillard-Després S, Witte OW, Redecker C, Geis C, Kunze A.

J Neurosci. 2019 Feb 27;39(9):1755-1766. doi: 10.1523/JNEUROSCI.3303-17.2018. Epub 2019 Jan 7.

48.

Talk About Thrombolysis. Regular Case-Based Discussions of Stroke Thrombolysis Improve Door-to-Needle Time by 20.

Klingner C, Günther A, Brodoehl S, Witte OW, Klingner CM.

J Stroke Cerebrovasc Dis. 2019 Apr;28(4):876-881. doi: 10.1016/j.jstrokecerebrovasdis.2018.12.002. Epub 2018 Dec 28.

PMID:
30598329
49.

Disease progression impacts health-related quality of life in amyotrophic lateral sclerosis.

Prell T, Gaur N, Stubendorff B, Rödiger A, Witte OW, Grosskreutz J.

J Neurol Sci. 2019 Feb 15;397:92-95. doi: 10.1016/j.jns.2018.12.035. Epub 2018 Dec 28.

PMID:
30597420
50.

Investigation of mitochondrial calcium uniporter role in embryonic and adult motor neurons from G93AhSOD1 mice.

Tadić V, Adam A, Goldhammer N, Lautenschlaeger J, Oberstadt M, Malci A, Le TT, Sengupta S, Stubendorff B, Keiner S, Witte OW, Grosskreutz J.

Neurobiol Aging. 2019 Mar;75:209-222. doi: 10.1016/j.neurobiolaging.2018.11.019. Epub 2018 Nov 23.

PMID:
30597405

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