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Items: 1 to 50 of 411

1.

Context-Dependent Role of Vinculin in Neutrophil Adhesion, Motility and Trafficking.

Wilson ZS, Witt H, Hazlett L, Harman M, Neumann BM, Whitman A, Patel M, Ross RS, Franck C, Reichner JS, Lefort CT.

Sci Rep. 2020 Feb 7;10(1):2142. doi: 10.1038/s41598-020-58882-y.

2.

Variants That Affect Function of Calcium Channel TRPV6 Are Associated With Early-onset Chronic Pancreatitis.

Masamune A, Kotani H, Sörgel FL, Chen JM, Hamada S, Sakaguchi R, Masson E, Nakano E, Kakuta Y, Niihori T, Funayama R, Shirota M, Hirano T, Kawamoto T, Hosokoshi A, Kume K, Unger L, Ewers M, Laumen H, Bugert P, Mori MX, Tsvilovskyy V, Weißgerber P, Kriebs U, Fecher-Trost C, Freichel M, Diakopoulos KN, Berninger A, Lesina M, Ishii K, Itoi T, Ikeura T, Okazaki K, Kaune T, Rosendahl J, Nagasaki M, Uezono Y, Algül H, Nakayama K, Matsubara Y, Aoki Y, Férec C, Mori Y, Witt H, Shimosegawa T.

Gastroenterology. 2020 Jan 10. pii: S0016-5085(20)30017-2. doi: 10.1053/j.gastro.2020.01.005. [Epub ahead of print]

PMID:
31930989
3.

Diffuse glioneuronal tumour with oligodendroglioma-like features and nuclear clusters (DGONC) - a molecularly defined glioneuronal CNS tumour class displaying recurrent monosomy 14.

Deng MY, Sill M, Sturm D, Stichel D, Witt H, Ecker J, Wittmann A, Schittenhelm J, Ebinger M, Schuhmann MU, Figarella-Branger D, Aronica E, Staszewski O, Preusser M, Haberler C, Lauten M, Schüller U, Hartmann C, Snuderl M, Dunham C, Jabado N, Wesseling P, Deckert M, Keyvani K, Gottardo N, Giangaspero F, von Hoff K, Ellison DW, Pietsch T, Herold-Mende C, Milde T, Witt O, Kool M, Korshunov A, Wick W, von Deimling A, Pfister SM, Jones DTW, Sahm F.

Neuropathol Appl Neurobiol. 2019 Dec 23. doi: 10.1111/nan.12590. [Epub ahead of print]

PMID:
31867747
4.

The effect of talc particles on phagocytes in co-culture with ovarian cancer cells.

Mandarino A, Gregory DJ, McGuire CC, Leblanc BW, Witt H, Rivera LM, Godleski JJ, Fedulov AV.

Environ Res. 2020 Jan;180:108676. doi: 10.1016/j.envres.2019.108676. Epub 2019 Aug 22.

PMID:
31785414
5.

Lateral Subunit Coupling Determines Intermediate Filament Mechanics.

Lorenz C, Forsting J, Schepers AV, Kraxner J, Bauch S, Witt H, Klumpp S, Köster S.

Phys Rev Lett. 2019 Nov 1;123(18):188102. doi: 10.1103/PhysRevLett.123.188102.

PMID:
31763918
6.

Molecular characterization of histopathological ependymoma variants.

Neumann JE, Spohn M, Obrecht D, Mynarek M, Thomas C, Hasselblatt M, Dorostkar MM, Wefers AK, Frank S, Monoranu CM, Koch A, Witt H, Kool M, Pajtler KW, Rutkowski S, Glatzel M, Schüller U.

Acta Neuropathol. 2020 Feb;139(2):305-318. doi: 10.1007/s00401-019-02090-0. Epub 2019 Nov 2.

PMID:
31679042
7.

Common variants in glyoxalase I do not increase chronic pancreatitis risk.

Kaune T, Hollenbach M, Keil B, Chen JM, Masson E, Becker C, Damm M, Ruffert C, Grützmann R, Hoffmeister A, Te Morsche RHM, Cavestro GM, Zuppardo RA, Saftoiu A, Malecka-Panas E, Głuszek S, Bugert P, Lerch MM, Weiss FU, Zou WB, Liao Z, Hegyi P, Drenth JP, Riedel J, Férec C, Scholz M, Kirsten H, Tóth A, Ewers M, Witt H, Griesmann H, Michl P, Rosendahl J.

PLoS One. 2019 Oct 29;14(10):e0222927. doi: 10.1371/journal.pone.0222927. eCollection 2019.

8.

Highly Elevated Plasma γ-Glutamyltransferase Elevations: A Trait Caused by γ-Glutamyltransferase 1 Transmembrane Mutations.

De Grandi A, Franzini M, Rosipal Š, Rosipal R, Debreova M, Corti A, Ruetzler-Dichtl E, Scholl-Bürgi S, Paolicchi A, Pompella A, Emdin M, Zampa G, Witt H, Zoller H, Tilg H, Mayatepek E, Herebian D, Pramstaller PP, Müller T, Janecke AR.

Hepatology. 2019 Sep 13. doi: 10.1002/hep.30944. [Epub ahead of print] No abstract available.

PMID:
31520399
9.

Vimentin Intermediate Filaments Undergo Irreversible Conformational Changes during Cyclic Loading.

Forsting J, Kraxner J, Witt H, Janshoff A, Köster S.

Nano Lett. 2019 Oct 9;19(10):7349-7356. doi: 10.1021/acs.nanolett.9b02972. Epub 2019 Sep 9.

PMID:
31498648
10.

MYCN amplification drives an aggressive form of spinal ependymoma.

Ghasemi DR, Sill M, Okonechnikov K, Korshunov A, Yip S, Schutz PW, Scheie D, Kruse A, Harter PN, Kastelan M, Wagner M, Hartmann C, Benzel J, Maass KK, Khasraw M, Sträter R, Thomas C, Paulus W, Kratz CP, Witt H, Kawauchi D, Herold-Mende C, Sahm F, Brandner S, Kool M, Jones DTW, von Deimling A, Pfister SM, Reuss DE, Pajtler KW.

Acta Neuropathol. 2019 Dec;138(6):1075-1089. doi: 10.1007/s00401-019-02056-2. Epub 2019 Aug 14.

11.

Brainstem biopsy in pediatric diffuse intrinsic pontine glioma in the era of precision medicine: the INFORM study experience.

Pfaff E, El Damaty A, Balasubramanian GP, Blattner-Johnson M, Worst BC, Stark S, Witt H, Pajtler KW, van Tilburg CM, Witt R, Milde T, Jakobs M, Fiesel P, Frühwald MC, Hernáiz Driever P, Thomale UW, Schuhmann MU, Metzler M, Bochennek K, Simon T, Dürken M, Karremann M, Knirsch S, Ebinger M, von Bueren AO, Pietsch T, Herold-Mende C, Reuss DE, Kiening K, Lichter P, Eggert A, Kramm CM, Pfister SM, Jones DTW, Bächli H, Witt O.

Eur J Cancer. 2019 Jun;114:27-35. doi: 10.1016/j.ejca.2019.03.019. Epub 2019 Apr 22.

PMID:
31022591
12.

Newly Diagnosed Metastatic Intracranial Ependymoma in Children: Frequency, Molecular Characteristics, Treatment, and Outcome in the Prospective HIT Series.

Benesch M, Mynarek M, Witt H, Warmuth-Metz M, Pietsch T, Bison B, Pfister SM, Pajtler KW, Kool M, Schüller U, Pietschmann K, Juhnke BO, Tippelt S, Fleischhack G, Schmid I, Kramm CM, Vorwerk P, Beilken A, Classen CF, Hernáiz Driever P, Kropshofer G, Imschweiler T, Lemmer A, Kortmann RD, Rutkowski S, von Hoff K.

Oncologist. 2019 Sep;24(9):e921-e929. doi: 10.1634/theoncologist.2018-0489. Epub 2019 Mar 8.

13.

Protease-Sensitive Pancreatic Lipase Variants Are Associated With Early Onset Chronic Pancreatitis.

Lasher D, Szabó A, Masamune A, Chen JM, Xiao X, Whitcomb DC, Barmada MM, Ewers M, Ruffert C, Paliwal S, Issarapu P, Bhaskar S, Mani KR, Chandak GR, Laumen H, Masson E, Kume K, Hamada S, Nakano E, Seltsam K, Bugert P, Müller T, Groneberg DA, Shimosegawa T, Rosendahl J, Férec C, Lowe ME, Witt H, Sahin-Tóth M.

Am J Gastroenterol. 2019 Jun;114(6):974-983. doi: 10.14309/ajg.0000000000000051.

14.

IRF5 Is Required for Bacterial Clearance in Human M1-Polarized Macrophages, and IRF5 Immune-Mediated Disease Risk Variants Modulate This Outcome.

Hedl M, Yan J, Witt H, Abraham C.

J Immunol. 2019 Feb 1;202(3):920-930. doi: 10.4049/jimmunol.1800226. Epub 2018 Dec 28.

15.

Using 3D epigenomic maps of primary olfactory neuronal cells from living individuals to understand gene regulation.

Rhie SK, Schreiner S, Witt H, Armoskus C, Lay FD, Camarena A, Spitsyna VN, Guo Y, Berman BP, Evgrafov OV, Knowles JA, Farnham PJ.

Sci Adv. 2018 Dec 13;4(12):eaav8550. doi: 10.1126/sciadv.aav8550. eCollection 2018 Dec.

16.

Three-dimensional analysis reveals altered chromatin interaction by enhancer inhibitors harbors TCF7L2-regulated cancer gene signature.

Gerrard DL, Wang Y, Gaddis M, Zhou Y, Wang J, Witt H, Lin S, Farnham PJ, Jin VX, Frietze SE.

J Cell Biochem. 2019 Mar;120(3):3056-3070. doi: 10.1002/jcb.27449. Epub 2018 Dec 11.

17.

Adhesion strategies of Dictyostelium discoideum- a force spectroscopy study.

Kamprad N, Witt H, Schröder M, Kreis CT, Bäumchen O, Janshoff A, Tarantola M.

Nanoscale. 2018 Dec 21;10(47):22504-22519. doi: 10.1039/c8nr07107a. Epub 2018 Nov 27.

PMID:
30480299
18.

Comprehensive plasma and tissue profiling reveals systemic metabolic alterations in cardiac hypertrophy and failure.

Müller OJ, Heckmann MB, Ding L, Rapti K, Rangrez AY, Gerken T, Christiansen N, Rennefahrt UEE, Witt H, González Maldonado S, Ternes P, Schwab DM, Ruf T, Hille S, Remes A, Jungmann A, Weis TM, Kreußer JS, Gröne HJ, Backs J, Schatz P, Katus HA, Frey N.

Cardiovasc Res. 2019 Jul 1;115(8):1296-1305. doi: 10.1093/cvr/cvy274.

PMID:
30418544
19.

Using Force Spectroscopy to Probe Coiled-Coil Assembly and Membrane Fusion.

Witt H, Janshoff A.

Methods Mol Biol. 2019;1860:145-159. doi: 10.1007/978-1-4939-8760-3_8.

PMID:
30317502
20.

DNA methylation-based classification of ependymomas in adulthood: implications for diagnosis and treatment.

Witt H, Gramatzki D, Hentschel B, Pajtler KW, Felsberg J, Schackert G, Löffler M, Capper D, Sahm F, Sill M, von Deimling A, Kool M, Herrlinger U, Westphal M, Pietsch T, Reifenberger G, Pfister SM, Tonn JC, Weller M; German Glioma Network.

Neuro Oncol. 2018 Nov 12;20(12):1616-1624. doi: 10.1093/neuonc/noy118.

21.

Heterogeneity within the PF-EPN-B ependymoma subgroup.

Cavalli FMG, Hübner JM, Sharma T, Luu B, Sill M, Zapotocky M, Mack SC, Witt H, Lin T, Shih DJH, Ho B, Santi M, Emery L, Hukin J, Dunham C, McLendon RE, Lipp ES, Gururangan S, Grossbach A, French P, Kros JM, van Veelen MC, Rao AAN, Giannini C, Leary S, Jung S, Faria CC, Mora J, Schüller U, Alonso MM, Chan JA, Klekner A, Chambless LB, Hwang EI, Massimino M, Eberhart CG, Karajannis MA, Lu B, Liau LM, Zollo M, Ferrucci V, Carlotti C, Tirapelli DPC, Tabori U, Bouffet E, Ryzhova M, Ellison DW, Merchant TE, Gilbert MR, Armstrong TS, Korshunov A, Pfister SM, Taylor MD, Aldape K, Pajtler KW, Kool M, Ramaswamy V.

Acta Neuropathol. 2018 Aug;136(2):227-237. doi: 10.1007/s00401-018-1888-x. Epub 2018 Jul 17.

22.

Molecular Diagnostics in Pediatric Brain Tumors: Impact on Diagnosis and Clinical Decision-Making - A Selected Case Series.

Bächli H, Ecker J, van Tilburg C, Sturm D, Selt F, Sahm F, Koelsche C, Grund K, Sutter C, Pietsch T, Witt H, Herold-Mende C, von Deimling A, Jones D, Pfister S, Witt O, Milde T.

Klin Padiatr. 2018 Oct;230(6):305-313. doi: 10.1055/a-0637-9653. Epub 2018 Jul 11.

PMID:
29996150
23.

Multireader Study on the Diagnostic Accuracy of Ultrafast Breast Magnetic Resonance Imaging for Breast Cancer Screening.

van Zelst JCM, Vreemann S, Witt HJ, Gubern-Merida A, Dorrius MD, Duvivier K, Lardenoije-Broker S, Lobbes MBI, Loo C, Veldhuis W, Veltman J, Drieling D, Karssemeijer N, Mann RM.

Invest Radiol. 2018 Oct;53(10):579-586. doi: 10.1097/RLI.0000000000000494.

PMID:
29944483
24.

Viscoelastic properties of vimentin originate from nonequilibrium conformational changes.

Block J, Witt H, Candelli A, Danes JC, Peterman EJG, Wuite GJL, Janshoff A, Köster S.

Sci Adv. 2018 Jun 13;4(6):eaat1161. doi: 10.1126/sciadv.aat1161. eCollection 2018 Jun.

25.

Molecular heterogeneity and CXorf67 alterations in posterior fossa group A (PFA) ependymomas.

Pajtler KW, Wen J, Sill M, Lin T, Orisme W, Tang B, Hübner JM, Ramaswamy V, Jia S, Dalton JD, Haupfear K, Rogers HA, Punchihewa C, Lee R, Easton J, Wu G, Ritzmann TA, Chapman R, Chavez L, Boop FA, Klimo P, Sabin ND, Ogg R, Mack SC, Freibaum BD, Kim HJ, Witt H, Jones DTW, Vo B, Gajjar A, Pounds S, Onar-Thomas A, Roussel MF, Zhang J, Taylor JP, Merchant TE, Grundy R, Tatevossian RG, Taylor MD, Pfister SM, Korshunov A, Kool M, Ellison DW.

Acta Neuropathol. 2018 Aug;136(2):211-226. doi: 10.1007/s00401-018-1877-0. Epub 2018 Jun 16.

26.

Common variants in the CLDN2-MORC4 and PRSS1-PRSS2 loci confer susceptibility to acute pancreatitis.

Weiss FU, Hesselbarth N, Párniczky A, Mosztbacher D, Lämmerhirt F, Ruffert C, Kovacs P, Beer S, Seltsam K, Griesmann H, Böhme R, Kaune T, Hollenbach M, Schulz HU, Simon P, Mayerle J, Lerch MM, Cavestro GM, Zuppardo RA, Di Leo M, Testoni PA, Malecka-Panas E, Gasirowska A, Głuszek S, Bugert P, Szentesi A, Mössner J, Witt H, Michl P, Hégyi P, Scholz M, Rosendahl J.

Pancreatology. 2018 Jun 1. pii: S1424-3903(18)30605-7. doi: 10.1016/j.pan.2018.05.486. [Epub ahead of print]

PMID:
29884332
27.

Author Correction: The landscape of genomic alterations across childhood cancers.

Gröbner SN, Worst BC, Weischenfeldt J, Buchhalter I, Kleinheinz K, Rudneva VA, Johann PD, Balasubramanian GP, Segura-Wang M, Brabetz S, Bender S, Hutter B, Sturm D, Pfaff E, Hübschmann D, Zipprich G, Heinold M, Eils J, Lawerenz C, Erkek S, Lambo S, Waszak S, Blattmann C, Borkhardt A, Kuhlen M, Eggert A, Fulda S, Gessler M, Wegert J, Kappler R, Baumhoer D, Burdach S, Kirschner-Schwabe R, Kontny U, Kulozik AE, Lohmann D, Hettmer S, Eckert C, Bielack S, Nathrath M, Niemeyer C, Richter GH, Schulte J, Siebert R, Westermann F, Molenaar JJ, Vassal G, Witt H, Burkhardt B, Kratz CP, Witt O, van Tilburg CM, Kramm CM, Fleischhack G, Dirksen U, Rutkowski S, Frühwald M, von Hoff K, Wolf S, Klingebiel T, Koscielniak E, Landgraf P, Koster J, Resnick AC, Zhang J, Liu Y, Zhou X, Waanders AJ, Zwijnenburg DA, Raman P, Brors B, Weber UD, Northcott PA, Pajtler KW, Kool M, Piro RM, Korbel JO, Schlesner M, Eils R, Jones DTW, Lichter P, Chavez L, Zapatka M, Pfister SM; ICGC PedBrain-Seq Project; ICGC MMML-Seq Project.

Nature. 2018 Jul;559(7714):E10. doi: 10.1038/s41586-018-0167-2.

PMID:
29875405
28.

The Nonbilayer Lipid MGDG and the Major Light-Harvesting Complex (LHCII) Promote Membrane Stacking in Supported Lipid Bilayers.

Seiwert D, Witt H, Ritz S, Janshoff A, Paulsen H.

Biochemistry. 2018 Apr 17;57(15):2278-2288. doi: 10.1021/acs.biochem.8b00118. Epub 2018 Apr 3.

PMID:
29577715
29.

DNA methylation-based classification of central nervous system tumours.

Capper D, Jones DTW, Sill M, Hovestadt V, Schrimpf D, Sturm D, Koelsche C, Sahm F, Chavez L, Reuss DE, Kratz A, Wefers AK, Huang K, Pajtler KW, Schweizer L, Stichel D, Olar A, Engel NW, Lindenberg K, Harter PN, Braczynski AK, Plate KH, Dohmen H, Garvalov BK, Coras R, Hölsken A, Hewer E, Bewerunge-Hudler M, Schick M, Fischer R, Beschorner R, Schittenhelm J, Staszewski O, Wani K, Varlet P, Pages M, Temming P, Lohmann D, Selt F, Witt H, Milde T, Witt O, Aronica E, Giangaspero F, Rushing E, Scheurlen W, Geisenberger C, Rodriguez FJ, Becker A, Preusser M, Haberler C, Bjerkvig R, Cryan J, Farrell M, Deckert M, Hench J, Frank S, Serrano J, Kannan K, Tsirigos A, Brück W, Hofer S, Brehmer S, Seiz-Rosenhagen M, Hänggi D, Hans V, Rozsnoki S, Hansford JR, Kohlhof P, Kristensen BW, Lechner M, Lopes B, Mawrin C, Ketter R, Kulozik A, Khatib Z, Heppner F, Koch A, Jouvet A, Keohane C, Mühleisen H, Mueller W, Pohl U, Prinz M, Benner A, Zapatka M, Gottardo NG, Driever PH, Kramm CM, Müller HL, Rutkowski S, von Hoff K, Frühwald MC, Gnekow A, Fleischhack G, Tippelt S, Calaminus G, Monoranu CM, Perry A, Jones C, Jacques TS, Radlwimmer B, Gessi M, Pietsch T, Schramm J, Schackert G, Westphal M, Reifenberger G, Wesseling P, Weller M, Collins VP, Blümcke I, Bendszus M, Debus J, Huang A, Jabado N, Northcott PA, Paulus W, Gajjar A, Robinson GW, Taylor MD, Jaunmuktane Z, Ryzhova M, Platten M, Unterberg A, Wick W, Karajannis MA, Mittelbronn M, Acker T, Hartmann C, Aldape K, Schüller U, Buslei R, Lichter P, Kool M, Herold-Mende C, Ellison DW, Hasselblatt M, Snuderl M, Brandner S, Korshunov A, von Deimling A, Pfister SM.

Nature. 2018 Mar 22;555(7697):469-474. doi: 10.1038/nature26000. Epub 2018 Mar 14.

30.

The landscape of genomic alterations across childhood cancers.

Gröbner SN, Worst BC, Weischenfeldt J, Buchhalter I, Kleinheinz K, Rudneva VA, Johann PD, Balasubramanian GP, Segura-Wang M, Brabetz S, Bender S, Hutter B, Sturm D, Pfaff E, Hübschmann D, Zipprich G, Heinold M, Eils J, Lawerenz C, Erkek S, Lambo S, Waszak S, Blattmann C, Borkhardt A, Kuhlen M, Eggert A, Fulda S, Gessler M, Wegert J, Kappler R, Baumhoer D, Burdach S, Kirschner-Schwabe R, Kontny U, Kulozik AE, Lohmann D, Hettmer S, Eckert C, Bielack S, Nathrath M, Niemeyer C, Richter GH, Schulte J, Siebert R, Westermann F, Molenaar JJ, Vassal G, Witt H; ICGC PedBrain-Seq Project; ICGC MMML-Seq Project, Burkhardt B, Kratz CP, Witt O, van Tilburg CM, Kramm CM, Fleischhack G, Dirksen U, Rutkowski S, Frühwald M, von Hoff K, Wolf S, Klingebiel T, Koscielniak E, Landgraf P, Koster J, Resnick AC, Zhang J, Liu Y, Zhou X, Waanders AJ, Zwijnenburg DA, Raman P, Brors B, Weber UD, Northcott PA, Pajtler KW, Kool M, Piro RM, Korbel JO, Schlesner M, Eils R, Jones DTW, Lichter P, Chavez L, Zapatka M, Pfister SM.

Nature. 2018 Mar 15;555(7696):321-327. doi: 10.1038/nature25480. Epub 2018 Feb 28. Erratum in: Nature. 2018 Jul;559(7714):E10.

PMID:
29489754
31.

ZFX acts as a transcriptional activator in multiple types of human tumors by binding downstream of transcription start sites at the majority of CpG island promoters.

Rhie SK, Yao L, Luo Z, Witt H, Schreiner S, Guo Y, Perez AA, Farnham PJ.

Genome Res. 2018 Feb 2. pii: gr.228809.117. doi: 10.1101/gr.228809.117. [Epub ahead of print]

32.

EPC/HPSG evidence-based guidelines for the management of pediatric pancreatitis.

Párniczky A, Abu-El-Haija M, Husain S, Lowe M, Oracz G, Sahin-Tóth M, Szabó FK, Uc A, Wilschanski M, Witt H, Czakó L, Grammatikopoulos T, Rasmussen IC, Sutton R, Hegyi P.

Pancreatology. 2018 Mar;18(2):146-160. doi: 10.1016/j.pan.2018.01.001. Epub 2018 Jan 4. Review.

PMID:
29398347
33.

Identification of essential amino acids for glucose transporter 5 (GLUT5)-mediated fructose transport.

Ebert K, Ewers M, Bisha I, Sander S, Rasputniac T, Daniel H, Antes I, Witt H.

J Biol Chem. 2018 Feb 9;293(6):2115-2124. doi: 10.1074/jbc.RA117.001442. Epub 2017 Dec 19.

34.

Therapeutic targeting of ependymoma as informed by oncogenic enhancer profiling.

Mack SC, Pajtler KW, Chavez L, Okonechnikov K, Bertrand KC, Wang X, Erkek S, Federation A, Song A, Lee C, Wang X, McDonald L, Morrow JJ, Saiakhova A, Sin-Chan P, Wu Q, Michaelraj KA, Miller TE, Hubert CG, Ryzhova M, Garzia L, Donovan L, Dombrowski S, Factor DC, Luu B, Valentim CLL, Gimple RC, Morton A, Kim L, Prager BC, Lee JJY, Wu X, Zuccaro J, Thompson Y, Holgado BL, Reimand J, Ke SQ, Tropper A, Lai S, Vijayarajah S, Doan S, Mahadev V, Miñan AF, Gröbner SN, Lienhard M, Zapatka M, Huang Z, Aldape KD, Carcaboso AM, Houghton PJ, Keir ST, Milde T, Witt H, Li Y, Li CJ, Bian XW, Jones DTW, Scott I, Singh SK, Huang A, Dirks PB, Bouffet E, Bradner JE, Ramaswamy V, Jabado N, Rutka JT, Northcott PA, Lupien M, Lichter P, Korshunov A, Scacheri PC, Pfister SM, Kool M, Taylor MD, Rich JN.

Nature. 2018 Jan 4;553(7686):101-105. doi: 10.1038/nature25169. Epub 2017 Dec 20.

35.

Branched-chain amino acid catabolism rather than amino acids plasma concentrations is associated with diet-induced changes in insulin resistance in overweight to obese individuals.

Haufe S, Engeli S, Kaminski J, Witt H, Rein D, Kamlage B, Utz W, Fuhrmann JC, Haas V, Mähler A, Schulz-Menger J, Luft FC, Boschmann M, Jordan J.

Nutr Metab Cardiovasc Dis. 2017 Oct;27(10):858-864. doi: 10.1016/j.numecd.2017.07.001. Epub 2017 Jul 11.

PMID:
28958691
36.

Genome-wide association study identifies inversion in the CTRB1-CTRB2 locus to modify risk for alcoholic and non-alcoholic chronic pancreatitis.

Rosendahl J, Kirsten H, Hegyi E, Kovacs P, Weiss FU, Laumen H, Lichtner P, Ruffert C, Chen JM, Masson E, Beer S, Zimmer C, Seltsam K, Algül H, Bühler F, Bruno MJ, Bugert P, Burkhardt R, Cavestro GM, Cichoz-Lach H, Farré A, Frank J, Gambaro G, Gimpfl S, Grallert H, Griesmann H, Grützmann R, Hellerbrand C, Hegyi P, Hollenbach M, Iordache S, Jurkowska G, Keim V, Kiefer F, Krug S, Landt O, Leo MD, Lerch MM, Lévy P, Löffler M, Löhr M, Ludwig M, Macek M, Malats N, Malecka-Panas E, Malerba G, Mann K, Mayerle J, Mohr S, Te Morsche RHM, Motyka M, Mueller S, Müller T, Nöthen MM, Pedrazzoli S, Pereira SP, Peters A, Pfützer R, Real FX, Rebours V, Ridinger M, Rietschel M, Rösmann E, Saftoiu A, Schneider A, Schulz HU, Soranzo N, Soyka M, Simon P, Skipworth J, Stickel F, Strauch K, Stumvoll M, Testoni PA, Tönjes A, Werner L, Werner J, Wodarz N, Ziegler M, Masamune A, Mössner J, Férec C, Michl P, P H Drenth J, Witt H, Scholz M, Sahin-Tóth M; all members of the PanEuropean Working group on ACP.

Gut. 2018 Oct;67(10):1855-1863. doi: 10.1136/gutjnl-2017-314454. Epub 2017 Jul 28.

37.

The non-bilayer lipid MGDG stabilizes the major light-harvesting complex (LHCII) against unfolding.

Seiwert D, Witt H, Janshoff A, Paulsen H.

Sci Rep. 2017 Jul 11;7(1):5158. doi: 10.1038/s41598-017-05328-7.

38.

Integrating Tenascin-C protein expression and 1q25 copy number status in pediatric intracranial ependymoma prognostication: A new model for risk stratification.

Andreiuolo F, Le Teuff G, Bayar MA, Kilday JP, Pietsch T, von Bueren AO, Witt H, Korshunov A, Modena P, Pfister SM, Pagès M, Castel D, Giangaspero F, Chimelli L, Varlet P, Rutkowski S, Frappaz D, Massimino M, Grundy R, Grill J; SIOP Ependymoma Biology Working Group BIOMECA (BIOlogical Markers for Ependymomas in Children and Adolescents).

PLoS One. 2017 Jun 15;12(6):e0178351. doi: 10.1371/journal.pone.0178351. eCollection 2017.

39.

[No Magic Bullet: Genetic Diagnostics and Predictive Testing].

Witt H.

Dtsch Med Wochenschr. 2017 May;142(9):652-656. doi: 10.1055/s-0043-101829. Epub 2017 Apr 28. German.

PMID:
28454198
40.

Metabolic profiles in heart failure due to non-ischemic cardiomyopathy at rest and under exercise.

Mueller-Hennessen M, Sigl J, Fuhrmann JC, Witt H, Reszka R, Schmitz O, Kastler J, Fischer JJ, Müller OJ, Giannitsis E, Weis T, Frey N, Katus HA.

ESC Heart Fail. 2017 May;4(2):178-189. doi: 10.1002/ehf2.12133. Epub 2017 Mar 8.

41.

Prognostic relevance of miR-124-3p and its target TP53INP1 in pediatric ependymoma.

Margolin-Miller Y, Yanichkin N, Shichrur K, Toledano H, Ohali A, Tzaridis T, Michowitz S, Fichman-Horn S, Feinmesser M, Pfister SM, Witt H, Tabori U, Bouffet E, Ramaswamy V, Hawkins C, Taylor MD, Yaniv I, Avigad S.

Genes Chromosomes Cancer. 2017 Aug;56(8):639-650. doi: 10.1002/gcc.22467. Epub 2017 May 19.

PMID:
28437838
42.

United European Gastroenterology evidence-based guidelines for the diagnosis and therapy of chronic pancreatitis (HaPanEU).

Löhr JM, Dominguez-Munoz E, Rosendahl J, Besselink M, Mayerle J, Lerch MM, Haas S, Akisik F, Kartalis N, Iglesias-Garcia J, Keller J, Boermeester M, Werner J, Dumonceau JM, Fockens P, Drewes A, Ceyhan G, Lindkvist B, Drenth J, Ewald N, Hardt P, de Madaria E, Witt H, Schneider A, Manfredi R, Brøndum FJ, Rudolf S, Bollen T, Bruno M; HaPanEU/UEG Working Group.

United European Gastroenterol J. 2017 Mar;5(2):153-199. doi: 10.1177/2050640616684695. Epub 2017 Jan 16. Review.

43.

Nonlinear Loading-Rate-Dependent Force Response of Individual Vimentin Intermediate Filaments to Applied Strain.

Block J, Witt H, Candelli A, Peterman EJ, Wuite GJ, Janshoff A, Köster S.

Phys Rev Lett. 2017 Jan 27;118(4):048101. doi: 10.1103/PhysRevLett.118.048101. Epub 2017 Jan 24.

PMID:
28186786
44.

Reassessment of GLUT7 and GLUT9 as Putative Fructose and Glucose Transporters.

Ebert K, Ludwig M, Geillinger KE, Schoberth GC, Essenwanger J, Stolz J, Daniel H, Witt H.

J Membr Biol. 2017 Apr;250(2):171-182. doi: 10.1007/s00232-016-9945-7. Epub 2017 Jan 12.

PMID:
28083649
45.

A Novel Lipid Biomarker Panel for the Detection of Heart Failure with Reduced Ejection Fraction.

Mueller-Hennessen M, Düngen HD, Lutz M, Trippel TD, Kreuter M, Sigl J, Müller OJ, Tahirovic E, Witt H, Ternes P, Carvalho S, Peter E, Rein D, Schatz P, Herth F, Giannitsis E, Weis T, Frey N, Katus HA.

Clin Chem. 2017 Jan;63(1):267-277. doi: 10.1373/clinchem.2016.257279. Epub 2016 Oct 25.

PMID:
28062623
46.

The current consensus on the clinical management of intracranial ependymoma and its distinct molecular variants.

Pajtler KW, Mack SC, Ramaswamy V, Smith CA, Witt H, Smith A, Hansford JR, von Hoff K, Wright KD, Hwang E, Frappaz D, Kanemura Y, Massimino M, Faure-Conter C, Modena P, Tabori U, Warren KE, Holland EC, Ichimura K, Giangaspero F, Castel D, von Deimling A, Kool M, Dirks PB, Grundy RG, Foreman NK, Gajjar A, Korshunov A, Finlay J, Gilbertson RJ, Ellison DW, Aldape KD, Merchant TE, Bouffet E, Pfister SM, Taylor MD.

Acta Neuropathol. 2017 Jan;133(1):5-12. doi: 10.1007/s00401-016-1643-0. Epub 2016 Nov 17.

47.

Integrin Cross-Talk Regulates the Human Neutrophil Response to Fungal β-Glucan in the Context of the Extracellular Matrix: A Prominent Role for VLA3 in the Antifungal Response.

Johnson CM, O'Brien XM, Byrd AS, Parisi VE, Loosely AJ, Li W, Witt H, Faridi MH, LeFort CT, Gupta V, Kim M, Reichner JS.

J Immunol. 2017 Jan 1;198(1):318-334. doi: 10.4049/jimmunol.1502381. Epub 2016 Nov 16.

48.

SNARE-mediated membrane fusion trajectories derived from force-clamp experiments.

Oelkers M, Witt H, Halder P, Jahn R, Janshoff A.

Proc Natl Acad Sci U S A. 2016 Nov 15;113(46):13051-13056. Epub 2016 Nov 2.

49.

Low-dose Actinomycin-D treatment re-establishes the tumoursuppressive function of P53 in RELA-positive ependymoma.

Tzaridis T, Milde T, Pajtler KW, Bender S, Jones DT, Müller S, Wittmann A, Schlotter M, Kulozik AE, Lichter P, Peter Collins V, Witt O, Kool M, Korshunov A, Pfister SM, Witt H.

Oncotarget. 2016 Sep 20;7(38):61860-61873. doi: 10.18632/oncotarget.11452.

50.

Complex Formation of Human Proelastases with Procarboxypeptidases A1 and A2.

Szabó A, Pilsak C, Bence M, Witt H, Sahin-Tóth M.

J Biol Chem. 2016 Aug 19;291(34):17706-16. doi: 10.1074/jbc.M116.743237. Epub 2016 Jun 29.

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