Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 83

1.

The role of mutation bias in adaptive molecular evolution: insights from convergent changes in protein function.

Storz JF, Natarajan C, Signore AV, Witt CC, McCandlish DM, Stoltzfus A.

Philos Trans R Soc Lond B Biol Sci. 2019 Jul 22;374(1777):20180238. doi: 10.1098/rstb.2018.0238. Epub 2019 Jun 3.

PMID:
31154983
2.

Small-molecule-mediated chemical knock-down of MuRF1/MuRF2 and attenuation of diaphragm dysfunction in chronic heart failure.

Adams V, Bowen TS, Werner S, Barthel P, Amberger C, Konzer A, Graumann J, Sehr P, Lewis J, Provaznik J, Benes V, Büttner P, Gasch A, Mangner N, Witt CC, Labeit D, Linke A, Labeit S.

J Cachexia Sarcopenia Muscle. 2019 May 29. doi: 10.1002/jcsm.12448. [Epub ahead of print]

3.

Parallel Molecular Evolution in Pathways, Genes, and Sites in High-Elevation Hummingbirds Revealed by Comparative Transcriptomics.

Lim MCW, Witt CC, Graham CH, Dávalos LM.

Genome Biol Evol. 2019 Jun 1;11(6):1552-1572. doi: 10.1093/gbe/evz101.

4.

Deeply conserved susceptibility in a multi-host, multi-parasite system.

Barrow LN, McNew SM, Mitchell N, Galen SC, Lutz HL, Skeen H, Valqui T, Weckstein JD, Witt CC.

Ecol Lett. 2019 Jun;22(6):987-998. doi: 10.1111/ele.13263. Epub 2019 Mar 25.

PMID:
30912262
5.

Ecology, not distance, explains community composition in parasites of sky-island Audubon's Warblers.

Williamson JL, Wolf CJ, Barrow LN, Baumann MJ, Galen SC, Schmitt CJ, Schmitt DC, Winter AS, Witt CC.

Int J Parasitol. 2019 May;49(6):437-448. doi: 10.1016/j.ijpara.2018.11.012. Epub 2019 Mar 23.

PMID:
30910465
6.

Genomic sequence capture of haemosporidian parasites: Methods and prospects for enhanced study of host-parasite evolution.

Barrow LN, Allen JM, Huang X, Bensch S, Witt CC.

Mol Ecol Resour. 2019 Mar;19(2):400-410. doi: 10.1111/1755-0998.12977.

PMID:
30554480
7.

An extinct hummingbird species that never was: a cautionary tale about sampling issues in molecular phylogenetics.

PÉrez-emÁn JL, Ferreira JP, GutiÉrrez-Pinto N, Cuervo AM, CÉspedes LN, Witt CC, Cadena CD.

Zootaxa. 2018 Jul 2;4442(3):491-497. doi: 10.11646/zootaxa.4442.3.11.

PMID:
30313979
8.

Forest corridors between the central Andes and the southern Atlantic Forest enabled dispersal and peripatric diversification without niche divergence in a passerine.

Trujillo-Arias N, Calderón L, Santos FR, Miyaki CY, Aleixo A, Witt CC, Tubaro PL, Cabanne GS.

Mol Phylogenet Evol. 2018 Nov;128:221-232. doi: 10.1016/j.ympev.2018.08.005. Epub 2018 Aug 6.

PMID:
30092357
9.

Detecting introgression despite phylogenetic uncertainty: The case of the South American siskins.

Beckman EJ, Benham PM, Cheviron ZA, Witt CC.

Mol Ecol. 2018 Nov;27(22):4350-4367. doi: 10.1111/mec.14795. Epub 2018 Aug 14.

PMID:
30014549
10.

Why are tropical mountain passes "low" for some species? Genetic and stable-isotope tests for differentiation, migration and expansion in elevational generalist songbirds.

Gadek CR, Newsome SD, Beckman EJ, Chavez AN, Galen SC, Bautista E, Witt CC.

J Anim Ecol. 2018 May;87(3):741-753. doi: 10.1111/1365-2656.12779. Epub 2017 Nov 27.

PMID:
29105758
11.

The biomechanical origin of extreme wing allometry in hummingbirds.

Skandalis DA, Segre PS, Bahlman JW, Groom DJE, Welch KC Jr, Witt CC, McGuire JA, Dudley R, Lentink D, Altshuler DL.

Nat Commun. 2017 Oct 19;8(1):1047. doi: 10.1038/s41467-017-01223-x.

12.

Diversity, abundance, and host relationships of avian malaria and related haemosporidians in New Mexico pine forests.

Marroquin-Flores RA, Williamson JL, Chavez AN, Bauernfeind SM, Baumann MJ, Gadek CR, Johnson AB, McCullough JM, Witt CC, Barrow LN.

PeerJ. 2017 Aug 17;5:e3700. doi: 10.7717/peerj.3700. eCollection 2017.

13.

Genome-wide association study of borderline personality disorder reveals genetic overlap with bipolar disorder, major depression and schizophrenia.

Witt SH, Streit F, Jungkunz M, Frank J, Awasthi S, Reinbold CS, Treutlein J, Degenhardt F, Forstner AJ, Heilmann-Heimbach S, Dietl L, Schwarze CE, Schendel D, Strohmaier J, Abdellaoui A, Adolfsson R, Air TM, Akil H, Alda M, Alliey-Rodriguez N, Andreassen OA, Babadjanova G, Bass NJ, Bauer M, Baune BT, Bellivier F, Bergen S, Bethell A, Biernacka JM, Blackwood DHR, Boks MP, Boomsma DI, Børglum AD, Borrmann-Hassenbach M, Brennan P, Budde M, Buttenschøn HN, Byrne EM, Cervantes P, Clarke TK, Craddock N, Cruceanu C, Curtis D, Czerski PM, Dannlowski U, Davis T, de Geus EJC, Di Florio A, Djurovic S, Domenici E, Edenberg HJ, Etain B, Fischer SB, Forty L, Fraser C, Frye MA, Fullerton JM, Gade K, Gershon ES, Giegling I, Gordon SD, Gordon-Smith K, Grabe HJ, Green EK, Greenwood TA, Grigoroiu-Serbanescu M, Guzman-Parra J, Hall LS, Hamshere M, Hauser J, Hautzinger M, Heilbronner U, Herms S, Hitturlingappa S, Hoffmann P, Holmans P, Hottenga JJ, Jamain S, Jones I, Jones LA, Juréus A, Kahn RS, Kammerer-Ciernioch J, Kirov G, Kittel-Schneider S, Kloiber S, Knott SV, Kogevinas M, Landén M, Leber M, Leboyer M, Li QS, Lissowska J, Lucae S, Martin NG, Mayoral-Cleries F, McElroy SL, McIntosh AM, McKay JD, McQuillin A, Medland SE, Middeldorp CM, Milaneschi Y, Mitchell PB, Montgomery GW, Morken G, Mors O, Mühleisen TW, Müller-Myhsok B, Myers RM, Nievergelt CM, Nurnberger JI, O'Donovan MC, Loohuis LMO, Ophoff R, Oruc L, Owen MJ, Paciga SA, Penninx BWJH, Perry A, Pfennig A, Potash JB, Preisig M, Reif A, Rivas F, Rouleau GA, Schofield PR, Schulze TG, Schwarz M, Scott L, Sinnamon GCB, Stahl EA, Strauss J, Turecki G, Van der Auwera S, Vedder H, Vincent JB, Willemsen G, Witt CC, Wray NR, Xi HS; Bipolar Disorders Working Group of the Psychiatric Genomics Consortium; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium; Schizophrenia Working Group of the Psychiatric Genomics Consortium, Tadic A, Dahmen N, Schott BH, Cichon S, Nöthen MM, Ripke S, Mobascher A, Rujescu D, Lieb K, Roepke S, Schmahl C, Bohus M, Rietschel M.

Transl Psychiatry. 2017 Jun 20;7(6):e1155. doi: 10.1038/tp.2017.115.

14.

Why Do Phylogenomic Data Sets Yield Conflicting Trees? Data Type Influences the Avian Tree of Life more than Taxon Sampling.

Reddy S, Kimball RT, Pandey A, Hosner PA, Braun MJ, Hackett SJ, Han KL, Harshman J, Huddleston CJ, Kingston S, Marks BD, Miglia KJ, Moore WS, Sheldon FH, Witt CC, Yuri T, Braun EL.

Syst Biol. 2017 Sep 1;66(5):857-879. doi: 10.1093/sysbio/syx041.

PMID:
28369655
15.

Stability-Mediated Epistasis Restricts Accessible Mutational Pathways in the Functional Evolution of Avian Hemoglobin.

Kumar A, Natarajan C, Moriyama H, Witt CC, Weber RE, Fago A, Storz JF.

Mol Biol Evol. 2017 May 1;34(5):1240-1251. doi: 10.1093/molbev/msx085.

16.

Contrasting molecular and morphological evidence for the identification of an anomalous Buteo: a cautionary tale for hybrid diagnosis.

Clark WS, Galen SC, Hull JM, Mayo MA, Witt CC.

PeerJ. 2017 Jan 10;5:e2850. doi: 10.7717/peerj.2850. eCollection 2017.

17.

Predictable convergence in hemoglobin function has unpredictable molecular underpinnings.

Natarajan C, Hoffmann FG, Weber RE, Fago A, Witt CC, Storz JF.

Science. 2016 Oct 21;354(6310):336-339.

18.

Complementary shifts in photoreceptor spectral tuning unlock the full adaptive potential of ultraviolet vision in birds.

Toomey MB, Lind O, Frederiksen R, Curley RW Jr, Riedl KM, Wilby D, Schwartz SJ, Witt CC, Harrison EH, Roberts NW, Vorobyev M, McGraw KJ, Cornwall MC, Kelber A, Corbo JC.

Elife. 2016 Jul 12;5. pii: e15675. doi: 10.7554/eLife.15675.

19.

Phylogeography of the Vermilion Flycatcher species complex: Multiple speciation events, shifts in migratory behavior, and an apparent extinction of a Galápagos-endemic bird species.

Carmi O, Witt CC, Jaramillo A, Dumbacher JP.

Mol Phylogenet Evol. 2016 Sep;102:152-73. doi: 10.1016/j.ympev.2016.05.029. Epub 2016 May 24.

PMID:
27233443
20.

Ancient horizontal transfers of retrotransposons between birds and ancestors of human pathogenic nematodes.

Suh A, Witt CC, Menger J, Sadanandan KR, Podsiadlowski L, Gerth M, Weigert A, McGuire JA, Mudge J, Edwards SV, Rheindt FE.

Nat Commun. 2016 Apr 21;7:11396. doi: 10.1038/ncomms11396.

21.

Predictable evolution toward flightlessness in volant island birds.

Wright NA, Steadman DW, Witt CC.

Proc Natl Acad Sci U S A. 2016 Apr 26;113(17):4765-70. doi: 10.1073/pnas.1522931113. Epub 2016 Apr 11.

22.
23.

Effect of Acute Dietary Nitrate Consumption on Oxygen Consumption During Submaximal Exercise in Hypobaric Hypoxia.

Carriker CR, Mermier CM, Van Dusseldorp TA, Johnson KE, Beltz NM, Vaughan RA, McCormick JJ, Cole NH, Witt CC, Gibson AL.

Int J Sport Nutr Exerc Metab. 2016 Aug;26(4):315-22. doi: 10.1123/ijsnem.2015-0144. Epub 2015 Dec 2.

PMID:
26630309
24.

Contribution of a mutational hot spot to hemoglobin adaptation in high-altitude Andean house wrens.

Galen SC, Natarajan C, Moriyama H, Weber RE, Fago A, Benham PM, Chavez AN, Cheviron ZA, Storz JF, Witt CC.

Proc Natl Acad Sci U S A. 2015 Nov 10;112(45):13958-63. doi: 10.1073/pnas.1507300112. Epub 2015 Oct 12.

25.

Normal cardiac contraction in mice lacking the proline-alanine rich region and C1 domain of cardiac myosin binding protein C.

van Dijk SJ, Witt CC, Harris SP.

J Mol Cell Cardiol. 2015 Nov;88:124-32. doi: 10.1016/j.yjmcc.2015.09.006. Epub 2015 Oct 8.

26.

Induction of Ankrd1 in Dilated Cardiomyopathy Correlates with the Heart Failure Progression.

Bogomolovas J, Brohm K, Čelutkienė J, Balčiūnaitė G, Bironaitė D, Bukelskienė V, Daunoravičus D, Witt CC, Fielitz J, Grabauskienė V, Labeit S.

Biomed Res Int. 2015;2015:273936. doi: 10.1155/2015/273936. Epub 2015 Apr 16.

27.

Phylogeny and biogeography of the New World siskins and goldfinches: rapid, recent diversification in the Central Andes.

Beckman EJ, Witt CC.

Mol Phylogenet Evol. 2015 Jun;87:28-45. doi: 10.1016/j.ympev.2015.03.005. Epub 2015 Mar 19.

PMID:
25796324
28.

Diaphragm muscle fiber weakness and ubiquitin-proteasome activation in critically ill patients.

Hooijman PE, Beishuizen A, Witt CC, de Waard MC, Girbes AR, Spoelstra-de Man AM, Niessen HW, Manders E, van Hees HW, van den Brom CE, Silderhuis V, Lawlor MW, Labeit S, Stienen GJ, Hartemink KJ, Paul MA, Heunks LM, Ottenheijm CA.

Am J Respir Crit Care Med. 2015 May 15;191(10):1126-38. doi: 10.1164/rccm.201412-2214OC.

29.

Gene turnover in the avian globin gene families and evolutionary changes in hemoglobin isoform expression.

Opazo JC, Hoffmann FG, Natarajan C, Witt CC, Berenbrink M, Storz JF.

Mol Biol Evol. 2015 Apr;32(4):871-87. doi: 10.1093/molbev/msu341. Epub 2014 Dec 9.

30.

Investigation of manic and euthymic episodes identifies state- and trait-specific gene expression and STAB1 as a new candidate gene for bipolar disorder.

Witt SH, Juraeva D, Sticht C, Strohmaier J, Meier S, Treutlein J, Dukal H, Frank J, Lang M, Deuschle M, Schulze TG, Degenhardt F, Mattheisen M, Brors B, Cichon S, Nöthen MM, Witt CC, Rietschel M.

Transl Psychiatry. 2014 Aug 19;4:e426. doi: 10.1038/tp.2014.71.

31.

Integrating evolutionary and functional tests of adaptive hypotheses: a case study of altitudinal differentiation in hemoglobin function in an Andean Sparrow, Zonotrichia capensis.

Cheviron ZA, Natarajan C, Projecto-Garcia J, Eddy DK, Jones J, Carling MD, Witt CC, Moriyama H, Weber RE, Fago A, Storz JF.

Mol Biol Evol. 2014 Nov;31(11):2948-62. doi: 10.1093/molbev/msu234. Epub 2014 Aug 18.

32.
33.

Specimen collection: an essential tool.

Rocha LA, Aleixo A, Allen G, Almeda F, Baldwin CC, Barclay MV, Bates JM, Bauer AM, Benzoni F, Berns CM, Berumen ML, Blackburn DC, Blum S, Bolaños F, Bowie RC, Britz R, Brown RM, Cadena CD, Carpenter K, Ceríaco LM, Chakrabarty P, Chaves G, Choat JH, Clements KD, Collette BB, Collins A, Coyne J, Cracraft J, Daniel T, de Carvalho MR, de Queiroz K, Di Dario F, Drewes R, Dumbacher JP, Engilis A Jr, Erdmann MV, Eschmeyer W, Feldman CR, Fisher BL, Fjeldså J, Fritsch PW, Fuchs J, Getahun A, Gill A, Gomon M, Gosliner T, Graves GR, Griswold CE, Guralnick R, Hartel K, Helgen KM, Ho H, Iskandar DT, Iwamoto T, Jaafar Z, James HF, Johnson D, Kavanaugh D, Knowlton N, Lacey E, Larson HK, Last P, Leis JM, Lessios H, Liebherr J, Lowman M, Mahler DL, Mamonekene V, Matsuura K, Mayer GC, Mays H Jr, McCosker J, McDiarmid RW, McGuire J, Miller MJ, Mooi R, Mooi RD, Moritz C, Myers P, Nachman MW, Nussbaum RA, Foighil DÓ, Parenti LR, Parham JF, Paul E, Paulay G, Pérez-Emán J, Pérez-Matus A, Poe S, Pogonoski J, Rabosky DL, Randall JE, Reimer JD, Robertson DR, Rödel MO, Rodrigues MT, Roopnarine P, Rüber L, Ryan MJ, Sheldon F, Shinohara G, Short A, Simison WB, Smith-Vaniz WF, Springer VG, Stiassny M, Tello JG, Thompson CW, Trnski T, Tucker P, Valqui T, Vecchione M, Verheyen E, Wainwright PC, Wheeler TA, White WT, Will K, Williams JT, Williams G, Wilson EO, Winker K, Winterbottom R, Witt CC.

Science. 2014 May 23;344(6186):814-5. doi: 10.1126/science.344.6186.814. No abstract available.

PMID:
24855245
34.

Migrate small, sound big: functional constraints on body size promote tracheal elongation in cranes.

Jones MR, Witt CC.

J Evol Biol. 2014 Jun;27(6):1256-64. doi: 10.1111/jeb.12397. Epub 2014 May 6.

35.

Molecular phylogenetics and the diversification of hummingbirds.

McGuire JA, Witt CC, Remsen JV Jr, Corl A, Rabosky DL, Altshuler DL, Dudley R.

Curr Biol. 2014 Apr 14;24(8):910-6. doi: 10.1016/j.cub.2014.03.016. Epub 2014 Apr 3. Erratum in: Curr Biol. 2014 May 5;24(9):1038.

36.

Metabolic 'engines' of flight drive genome size reduction in birds.

Wright NA, Gregory TR, Witt CC.

Proc Biol Sci. 2014 Jan 29;281(1779):20132780. doi: 10.1098/rspb.2013.2780. Print 2014 Mar 22.

37.

Repeated elevational transitions in hemoglobin function during the evolution of Andean hummingbirds.

Projecto-Garcia J, Natarajan C, Moriyama H, Weber RE, Fago A, Cheviron ZA, Dudley R, McGuire JA, Witt CC, Storz JF.

Proc Natl Acad Sci U S A. 2013 Dec 17;110(51):20669-74. doi: 10.1073/pnas.1315456110. Epub 2013 Dec 2.

38.

In vivo and in vitro investigations of heterozygous nebulin knock-out mice disclose a mild skeletal muscle phenotype.

Gineste C, De Winter JM, Kohl C, Witt CC, Giannesini B, Brohm K, Le Fur Y, Gretz N, Vilmen C, Pecchi E, Jubeau M, Cozzone PJ, Stienen GJ, Granzier H, Labeit S, Ottenheijm CA, Bendahan D, Gondin J.

Neuromuscul Disord. 2013 Apr;23(4):357-69. doi: 10.1016/j.nmd.2012.12.011. Epub 2013 Feb 1.

PMID:
23375831
39.

Comparison of gene expression profiles in the blood, hippocampus and prefrontal cortex of rats.

Witt SH, Sommer WH, Hansson AC, Sticht C, Rietschel M, Witt CC.

In Silico Pharmacol. 2013 Nov 13;1:15. doi: 10.1186/2193-9616-1-15. eCollection 2013.

40.

Parsimony and model-based analyses of indels in avian nuclear genes reveal congruent and incongruent phylogenetic signals.

Yuri T, Kimball RT, Harshman J, Bowie RC, Braun MJ, Chojnowski JL, Han KL, Hackett SJ, Huddleston CJ, Moore WS, Reddy S, Sheldon FH, Steadman DW, Witt CC, Braun EL.

Biology (Basel). 2013 Mar 13;2(1):419-44. doi: 10.3390/biology2010419.

41.

Energetics, lifestyle, and reproduction in birds.

Sibly RM, Witt CC, Wright NA, Venditti C, Jetz W, Brown JH.

Proc Natl Acad Sci U S A. 2012 Jul 3;109(27):10937-41. doi: 10.1073/pnas.1206512109. Epub 2012 May 21.

42.

An improved phylogeny of the Andean tit-tyrants (Aves, Tyrannidae): more characters trump sophisticated analyses.

Dubay SG, Witt CC.

Mol Phylogenet Evol. 2012 Aug;64(2):285-96. doi: 10.1016/j.ympev.2012.04.002. Epub 2012 Apr 16.

43.

Selective diaphragm muscle weakness after contractile inactivity during thoracic surgery.

Welvaart WN, Paul MA, Stienen GJ, van Hees HW, Loer SA, Bouwman R, Niessen H, de Man FS, Witt CC, Granzier H, Vonk-Noordegraaf A, Ottenheijm CA.

Ann Surg. 2011 Dec;254(6):1044-9. doi: 10.1097/SLA.0b013e318232e75b.

PMID:
21975323
44.

Homoplastic microinversions and the avian tree of life.

Braun EL, Kimball RT, Han KL, Iuhasz-Velez NR, Bonilla AJ, Chojnowski JL, Smith JV, Bowie RC, Braun MJ, Hackett SJ, Harshman J, Huddleston CJ, Marks BD, Miglia KJ, Moore WS, Reddy S, Sheldon FH, Witt CC, Yuri T.

BMC Evol Biol. 2011 May 25;11:141. doi: 10.1186/1471-2148-11-141.

45.

Are transposable element insertions homoplasy free?: an examination using the avian tree of life.

Han KL, Braun EL, Kimball RT, Reddy S, Bowie RC, Braun MJ, Chojnowski JL, Hackett SJ, Harshman J, Huddleston CJ, Marks BD, Miglia KJ, Moore WS, Sheldon FH, Steadman DW, Witt CC, Yuri T.

Syst Biol. 2011 May;60(3):375-86. doi: 10.1093/sysbio/syq100. Epub 2011 Feb 8. No abstract available.

PMID:
21303823
46.

Modulation of muscle atrophy, fatigue and MLC phosphorylation by MuRF1 as indicated by hindlimb suspension studies on MuRF1-KO mice.

Labeit S, Kohl CH, Witt CC, Labeit D, Jung J, Granzier H.

J Biomed Biotechnol. 2010;2010:693741. doi: 10.1155/2010/693741. Epub 2010 Jun 24.

47.

Atrogin-1 and MuRF1 regulate cardiac MyBP-C levels via different mechanisms.

Mearini G, Gedicke C, Schlossarek S, Witt CC, Krämer E, Cao P, Gomes MD, Lecker SH, Labeit S, Willis MS, Eschenhagen T, Carrier L.

Cardiovasc Res. 2010 Jan 15;85(2):357-66. doi: 10.1093/cvr/cvp348. Epub 2009 Oct 22.

48.

DNA from a 100-year-old holotype confirms the validity of a potentially extinct hummingbird species.

Kirchman JJ, Witt CC, McGuire JA, Graves GR.

Biol Lett. 2010 Feb 23;6(1):112-5. doi: 10.1098/rsbl.2009.0545. Epub 2009 Sep 23.

49.

The smallest avian genomes are found in hummingbirds.

Gregory TR, Andrews CB, McGuire JA, Witt CC.

Proc Biol Sci. 2009 Nov 7;276(1674):3753-7. doi: 10.1098/rspb.2009.1004. Epub 2009 Aug 5.

50.

Thin filament length dysregulation contributes to muscle weakness in nemaline myopathy patients with nebulin deficiency.

Ottenheijm CA, Witt CC, Stienen GJ, Labeit S, Beggs AH, Granzier H.

Hum Mol Genet. 2009 Jul 1;18(13):2359-69. doi: 10.1093/hmg/ddp168. Epub 2009 Apr 4.

Supplemental Content

Support Center