Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 25

1.

Mapping Aldehyde Dehydrogenase 1A1 Activity using an [18F]Substrate-based Approach.

Pereira R, Gendron T, Sanghera C, Greenwood HE, Newcombe J, McCormick P, Sander K, Topf M, Årstad E, Witney TH.

Chemistry. 2018 Dec 6. doi: 10.1002/chem.201805473. [Epub ahead of print]

PMID:
30521138
2.

Assessment of tumor redox status through (S)-4-(3-[18F]fluoropropyl)-L-glutamic acid positron emission tomography imaging of system xc- activity.

McCormick PN, Greenwood HE, Glaser M, Maddocks ODK, Gendron T, Sander K, Gowrishankar G, Hoehne A, Zhang T, Shuhendler AJ, Lewis DY, Berndt M, Koglin N, Lythgoe MF, Gambhir SS, Årstad E, Witney TH.

Cancer Res. 2018 Nov 6. pii: canres.2634.2018. doi: 10.1158/0008-5472.CAN-18-2634. [Epub ahead of print]

PMID:
30401715
3.

[18F]FSPG-PET reveals increased cystine/glutamate antiporter (xc-) activity in a mouse model of multiple sclerosis.

Hoehne A, James ML, Alam IS, Ronald JA, Schneider B, D'Souza A, Witney TH, Andrews LE, Cropper HC, Behera D, Gowrishankar G, Ding Z, Wyss-Coray T, Chin FT, Biswal S, Gambhir SS.

J Neuroinflammation. 2018 Feb 22;15(1):55. doi: 10.1186/s12974-018-1080-1.

4.

Correction to: The relationship between endogenous thymidine concentrations and [18F]FLT uptake in a range of preclinical tumour models.

Heinzmann K, Honess DJ, Lewis DY, Smith DM, Cawthorne C, Keen H, Heskamp S, Schelhaas S, Witney TH, Soloviev D, Williams KJ, Jacobs AH, Aboagye EO, Griffiths JR, Brindle KM.

EJNMMI Res. 2017 Dec 15;7(1):99. doi: 10.1186/s13550-017-0349-1.

5.

3'-Deoxy-3'-[18F]Fluorothymidine Uptake Is Related to Thymidine Phosphorylase Expression in Various Experimental Tumor Models.

Schelhaas S, Heinzmann K, Honess DJ, Smith DM, Keen H, Heskamp S, Witney TH, Besret L, Doblas S, Griffiths JR, Aboagye EO, Jacobs AH.

Mol Imaging Biol. 2018 Apr;20(2):194-199. doi: 10.1007/s11307-017-1125-3.

6.

Rapid Imaging of Tumor Cell Death In Vivo Using the C2A Domain of Synaptotagmin-I.

Neves AA, Xie B, Fawcett S, Alam IS, Witney TH, de Backer MM, Summers J, Hughes W, McGuire S, Soloviev D, Miller J, Howat WJ, Hu DE, Rodrigues TB, Lewis DY, Brindle KM.

J Nucl Med. 2017 Jun;58(6):881-887. doi: 10.2967/jnumed.116.183004. Epub 2017 Feb 16.

7.

Reporter gene imaging of targeted T cell immunotherapy in recurrent glioma.

Keu KV, Witney TH, Yaghoubi S, Rosenberg J, Kurien A, Magnusson R, Williams J, Habte F, Wagner JR, Forman S, Brown C, Allen-Auerbach M, Czernin J, Tang W, Jensen MC, Badie B, Gambhir SS.

Sci Transl Med. 2017 Jan 18;9(373). pii: eaag2196. doi: 10.1126/scitranslmed.aag2196.

8.

The relationship between endogenous thymidine concentrations and [(18)F]FLT uptake in a range of preclinical tumour models.

Heinzmann K, Honess DJ, Lewis DY, Smith DM, Cawthorne C, Keen H, Heskamp S, Schelhaas S, Witney TH, Soloviev D, Williams KJ, Jacobs AH, Aboagye EO, Griffiths JR, Brindle KM.

EJNMMI Res. 2016 Dec;6(1):63. doi: 10.1186/s13550-016-0218-3. Epub 2016 Aug 11. Erratum in: EJNMMI Res. 2017 Dec 15;7(1):99.

9.

AshwaMAX and Withaferin A inhibits gliomas in cellular and murine orthotopic models.

Chang E, Pohling C, Natarajan A, Witney TH, Kaur J, Xu L, Gowrishankar G, D'Souza AL, Murty S, Schick S, Chen L, Wu N, Khaw P, Mischel P, Abbasi T, Usmani S, Mallick P, Gambhir SS.

J Neurooncol. 2016 Jan;126(2):253-64. doi: 10.1007/s11060-015-1972-1. Epub 2015 Dec 9.

10.

PET imaging of tumor glycolysis downstream of hexokinase through noninvasive measurement of pyruvate kinase M2.

Witney TH, James ML, Shen B, Chang E, Pohling C, Arksey N, Hoehne A, Shuhendler A, Park JH, Bodapati D, Weber J, Gowrishankar G, Rao J, Chin FT, Gambhir SS.

Sci Transl Med. 2015 Oct 21;7(310):310ra169. doi: 10.1126/scitranslmed.aac6117.

PMID:
26491079
11.

A Systematic Comparison of 18F-C-SNAT to Established Radiotracer Imaging Agents for the Detection of Tumor Response to Treatment.

Witney TH, Hoehne A, Reeves RE, Ilovich O, Namavari M, Shen B, Chin FT, Rao J, Gambhir SS.

Clin Cancer Res. 2015 Sep 1;21(17):3896-905. doi: 10.1158/1078-0432.CCR-14-3176. Epub 2015 May 13.

12.

Preclinical evaluation of 3-18F-fluoro-2,2-dimethylpropionic acid as an imaging agent for tumor detection.

Witney TH, Pisaneschi F, Alam IS, Trousil S, Kaliszczak M, Twyman F, Brickute D, Nguyen QD, Schug Z, Gottlieb E, Aboagye EO.

J Nucl Med. 2014 Sep;55(9):1506-12. doi: 10.2967/jnumed.114.140343. Epub 2014 Jul 10. Erratum in: J Nucl Med. 2014 Nov;55(11):1914.

13.

Preclinical assessment of carboplatin treatment efficacy in lung cancer by 18F-ICMT-11-positron emission tomography.

Witney TH, Fortt R, Aboagye EO.

PLoS One. 2014 Mar 11;9(3):e91694. doi: 10.1371/journal.pone.0091694. eCollection 2014. Erratum in: PLoS One. 2014;9(6):e100020. Fortt, Robin R [corrected to Fortt, R].

14.

A novel radiotracer to image glycogen metabolism in tumors by positron emission tomography.

Witney TH, Carroll L, Alam IS, Chandrashekran A, Nguyen QD, Sala R, Harris R, DeBerardinis RJ, Agarwal R, Aboagye EO.

Cancer Res. 2014 Mar 1;74(5):1319-28. doi: 10.1158/0008-5472.CAN-13-2768.

15.

Radiolabeled RGD tracer kinetics annotates differential αvβ 3 integrin expression linked to cell intrinsic and vessel expression.

Alam IS, Witney TH, Tomasi G, Carroll L, Twyman FJ, Nguyen QD, Aboagye EO.

Mol Imaging Biol. 2014 Aug;16(4):558-66. doi: 10.1007/s11307-013-0710-3. Epub 2013 Dec 6.

PMID:
24310722
16.

Magnetic resonance imaging with hyperpolarized [1,4-(13)C2]fumarate allows detection of early renal acute tubular necrosis.

Clatworthy MR, Kettunen MI, Hu DE, Mathews RJ, Witney TH, Kennedy BW, Bohndiek SE, Gallagher FA, Jarvis LB, Smith KG, Brindle KM.

Proc Natl Acad Sci U S A. 2012 Aug 14;109(33):13374-9. doi: 10.1073/pnas.1205539109. Epub 2012 Jul 26.

17.

Evaluation of deuterated 18F- and 11C-labeled choline analogs for cancer detection by positron emission tomography.

Witney TH, Alam IS, Turton DR, Smith G, Carroll L, Brickute D, Twyman FJ, Nguyen QD, Tomasi G, Awais RO, Aboagye EO.

Clin Cancer Res. 2012 Feb 15;18(4):1063-72. doi: 10.1158/1078-0432.CCR-11-2462. Epub 2012 Jan 10.

18.

Kinetic modeling of hyperpolarized 13C label exchange between pyruvate and lactate in tumor cells.

Witney TH, Kettunen MI, Brindle KM.

J Biol Chem. 2011 Jul 15;286(28):24572-80. doi: 10.1074/jbc.M111.237727. Epub 2011 May 19.

19.

Detection of tumor response to a vascular disrupting agent by hyperpolarized 13C magnetic resonance spectroscopy.

Bohndiek SE, Kettunen MI, Hu DE, Witney TH, Kennedy BW, Gallagher FA, Brindle KM.

Mol Cancer Ther. 2010 Dec;9(12):3278-88. doi: 10.1158/1535-7163.MCT-10-0706.

20.

Detecting treatment response in a model of human breast adenocarcinoma using hyperpolarised [1-13C]pyruvate and [1,4-13C2]fumarate.

Witney TH, Kettunen MI, Hu DE, Gallagher FA, Bohndiek SE, Napolitano R, Brindle KM.

Br J Cancer. 2010 Oct 26;103(9):1400-6. doi: 10.1038/sj.bjc.6605945. Epub 2010 Oct 5.

21.

Imaging tumour cell metabolism using hyperpolarized 13C magnetic resonance spectroscopy.

Witney TH, Brindle KM.

Biochem Soc Trans. 2010 Oct;38(5):1220-4. doi: 10.1042/BST0381220.

PMID:
20863288
22.

Comparison of the C2A domain of synaptotagmin-I and annexin-V as probes for detecting cell death.

Alam IS, Neves AA, Witney TH, Boren J, Brindle KM.

Bioconjug Chem. 2010 May 19;21(5):884-91. doi: 10.1021/bc9004415.

PMID:
20402461
23.

Magnetization transfer measurements of exchange between hyperpolarized [1-13C]pyruvate and [1-13C]lactate in a murine lymphoma.

Kettunen MI, Hu DE, Witney TH, McLaughlin R, Gallagher FA, Bohndiek SE, Day SE, Brindle KM.

Magn Reson Med. 2010 Apr;63(4):872-80. doi: 10.1002/mrm.22276.

24.

Production of hyperpolarized [1,4-13C2]malate from [1,4-13C2]fumarate is a marker of cell necrosis and treatment response in tumors.

Gallagher FA, Kettunen MI, Hu DE, Jensen PR, Zandt RI, Karlsson M, Gisselsson A, Nelson SK, Witney TH, Bohndiek SE, Hansson G, Peitersen T, Lerche MH, Brindle KM.

Proc Natl Acad Sci U S A. 2009 Nov 24;106(47):19801-6. doi: 10.1073/pnas.0911447106. Epub 2009 Nov 10.

25.

A comparison between radiolabeled fluorodeoxyglucose uptake and hyperpolarized (13)C-labeled pyruvate utilization as methods for detecting tumor response to treatment.

Witney TH, Kettunen MI, Day SE, Hu DE, Neves AA, Gallagher FA, Fulton SM, Brindle KM.

Neoplasia. 2009 Jun;11(6):574-82, 1 p following 582.

Supplemental Content

Loading ...
Support Center