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Items: 1 to 20 of 31

1.

Imaging of T-cells and their responses during anti-cancer immunotherapy.

Krekorian M, Fruhwirth GO, Srinivas M, Figdor CG, Heskamp S, Witney TH, Aarntzen EHJG.

Theranostics. 2019 Oct 16;9(25):7924-7947. doi: 10.7150/thno.37924.

2.

Evaluation of integrin αvβ6 cystine knot PET tracers to detect cancer and idiopathic pulmonary fibrosis.

Kimura RH, Wang L, Shen B, Huo L, Tummers W, Filipp FV, Guo HH, Haywood T, Abou-Elkacem L, Baratto L, Habte F, Devulapally R, Witney TH, Cheng Y, Tikole S, Chakraborti S, Nix J, Bonagura CA, Hatami N, Mooney JJ, Desai T, Turner S, Gaster RS, Otte A, Visser BC, Poultsides GA, Norton J, Park W, Stolowitz M, Lau K, Yang E, Natarajan A, Ilovich O, Srinivas S, Srinivasan A, Paulmurugan R, Willmann J, Chin FT, Cheng Z, Iagaru A, Li F, Gambhir SS.

Nat Commun. 2019 Oct 14;10(1):4673. doi: 10.1038/s41467-019-11863-w.

3.

High throughput PET/CT imaging using a multiple mouse imaging system.

Greenwood HE, Nyitrai Z, Mocsai G, Hobor S, Witney TH.

J Nucl Med. 2019 Sep 13. pii: jnumed.119.228692. doi: 10.2967/jnumed.119.228692. [Epub ahead of print]

PMID:
31519806
4.

[18F]-SuPAR: A Radiofluorinated Probe for Noninvasive Imaging of DNA Damage-Dependent Poly(ADP-ribose) Polymerase Activity.

Shuhendler AJ, Cui L, Chen Z, Shen B, Chen M, James ML, Witney TH, Bazalova-Carter M, Gambhir SS, Chin FT, Graves EE, Rao J.

Bioconjug Chem. 2019 May 15;30(5):1331-1342. doi: 10.1021/acs.bioconjchem.9b00089. Epub 2019 Apr 22.

PMID:
30973715
5.

Imaging Cancer Metabolism with Positron Emission Tomography (PET).

Witney TH, Lewis DY.

Methods Mol Biol. 2019;1928:29-44. doi: 10.1007/978-1-4939-9027-6_2.

PMID:
30725448
6.

Measurement of Tumor Antioxidant Capacity and Prediction of Chemotherapy Resistance in Preclinical Models of Ovarian Cancer by Positron Emission Tomography.

Greenwood HE, McCormick PN, Gendron T, Glaser M, Pereira R, Maddocks ODK, Sander K, Zhang T, Koglin N, Lythgoe MF, Årstad E, Hochhauser D, Witney TH.

Clin Cancer Res. 2019 Apr 15;25(8):2471-2482. doi: 10.1158/1078-0432.CCR-18-3423. Epub 2019 Jan 16.

7.

Mapping Aldehyde Dehydrogenase 1A1 Activity using an [18 F]Substrate-Based Approach.

Pereira R, Gendron T, Sanghera C, Greenwood HE, Newcombe J, McCormick PN, Sander K, Topf M, Årstad E, Witney TH.

Chemistry. 2019 Feb 11;25(9):2345-2351. doi: 10.1002/chem.201805473. Epub 2019 Jan 14.

8.

Assessment of Tumor Redox Status through (S)-4-(3-[18F]fluoropropyl)-L-Glutamic Acid PET Imaging of System xc - Activity.

McCormick PN, Greenwood HE, Glaser M, Maddocks ODK, Gendron T, Sander K, Gowrishankar G, Hoehne A, Zhang T, Shuhendler AJ, Lewis DY, Berndt M, Koglin N, Lythgoe MF, Gambhir SS, Årstad E, Witney TH.

Cancer Res. 2019 Feb 15;79(4):853-863. doi: 10.1158/0008-5472.CAN-18-2634. Epub 2018 Nov 6.

9.

[18F]FSPG-PET reveals increased cystine/glutamate antiporter (xc-) activity in a mouse model of multiple sclerosis.

Hoehne A, James ML, Alam IS, Ronald JA, Schneider B, D'Souza A, Witney TH, Andrews LE, Cropper HC, Behera D, Gowrishankar G, Ding Z, Wyss-Coray T, Chin FT, Biswal S, Gambhir SS.

J Neuroinflammation. 2018 Feb 22;15(1):55. doi: 10.1186/s12974-018-1080-1.

10.

Correction to: The relationship between endogenous thymidine concentrations and [18F]FLT uptake in a range of preclinical tumour models.

Heinzmann K, Honess DJ, Lewis DY, Smith DM, Cawthorne C, Keen H, Heskamp S, Schelhaas S, Witney TH, Soloviev D, Williams KJ, Jacobs AH, Aboagye EO, Griffiths JR, Brindle KM.

EJNMMI Res. 2017 Dec 15;7(1):99. doi: 10.1186/s13550-017-0349-1.

11.

3'-Deoxy-3'-[18F]Fluorothymidine Uptake Is Related to Thymidine Phosphorylase Expression in Various Experimental Tumor Models.

Schelhaas S, Heinzmann K, Honess DJ, Smith DM, Keen H, Heskamp S, Witney TH, Besret L, Doblas S, Griffiths JR, Aboagye EO, Jacobs AH.

Mol Imaging Biol. 2018 Apr;20(2):194-199. doi: 10.1007/s11307-017-1125-3.

12.

Rapid Imaging of Tumor Cell Death In Vivo Using the C2A Domain of Synaptotagmin-I.

Neves AA, Xie B, Fawcett S, Alam IS, Witney TH, de Backer MM, Summers J, Hughes W, McGuire S, Soloviev D, Miller J, Howat WJ, Hu DE, Rodrigues TB, Lewis DY, Brindle KM.

J Nucl Med. 2017 Jun;58(6):881-887. doi: 10.2967/jnumed.116.183004. Epub 2017 Feb 16.

13.

Reporter gene imaging of targeted T cell immunotherapy in recurrent glioma.

Keu KV, Witney TH, Yaghoubi S, Rosenberg J, Kurien A, Magnusson R, Williams J, Habte F, Wagner JR, Forman S, Brown C, Allen-Auerbach M, Czernin J, Tang W, Jensen MC, Badie B, Gambhir SS.

Sci Transl Med. 2017 Jan 18;9(373). pii: eaag2196. doi: 10.1126/scitranslmed.aag2196.

14.

The relationship between endogenous thymidine concentrations and [(18)F]FLT uptake in a range of preclinical tumour models.

Heinzmann K, Honess DJ, Lewis DY, Smith DM, Cawthorne C, Keen H, Heskamp S, Schelhaas S, Witney TH, Soloviev D, Williams KJ, Jacobs AH, Aboagye EO, Griffiths JR, Brindle KM.

EJNMMI Res. 2016 Dec;6(1):63. doi: 10.1186/s13550-016-0218-3. Epub 2016 Aug 11. Erratum in: EJNMMI Res. 2017 Dec 15;7(1):99.

15.

AshwaMAX and Withaferin A inhibits gliomas in cellular and murine orthotopic models.

Chang E, Pohling C, Natarajan A, Witney TH, Kaur J, Xu L, Gowrishankar G, D'Souza AL, Murty S, Schick S, Chen L, Wu N, Khaw P, Mischel P, Abbasi T, Usmani S, Mallick P, Gambhir SS.

J Neurooncol. 2016 Jan;126(2):253-64. doi: 10.1007/s11060-015-1972-1. Epub 2015 Dec 9.

16.

PET imaging of tumor glycolysis downstream of hexokinase through noninvasive measurement of pyruvate kinase M2.

Witney TH, James ML, Shen B, Chang E, Pohling C, Arksey N, Hoehne A, Shuhendler A, Park JH, Bodapati D, Weber J, Gowrishankar G, Rao J, Chin FT, Gambhir SS.

Sci Transl Med. 2015 Oct 21;7(310):310ra169. doi: 10.1126/scitranslmed.aac6117.

PMID:
26491079
17.

A Systematic Comparison of 18F-C-SNAT to Established Radiotracer Imaging Agents for the Detection of Tumor Response to Treatment.

Witney TH, Hoehne A, Reeves RE, Ilovich O, Namavari M, Shen B, Chin FT, Rao J, Gambhir SS.

Clin Cancer Res. 2015 Sep 1;21(17):3896-905. doi: 10.1158/1078-0432.CCR-14-3176. Epub 2015 May 13.

18.

Preclinical evaluation of 3-18F-fluoro-2,2-dimethylpropionic acid as an imaging agent for tumor detection.

Witney TH, Pisaneschi F, Alam IS, Trousil S, Kaliszczak M, Twyman F, Brickute D, Nguyen QD, Schug Z, Gottlieb E, Aboagye EO.

J Nucl Med. 2014 Sep;55(9):1506-12. doi: 10.2967/jnumed.114.140343. Epub 2014 Jul 10. Erratum in: J Nucl Med. 2014 Nov;55(11):1914.

19.

Preclinical assessment of carboplatin treatment efficacy in lung cancer by 18F-ICMT-11-positron emission tomography.

Witney TH, Fortt R, Aboagye EO.

PLoS One. 2014 Mar 11;9(3):e91694. doi: 10.1371/journal.pone.0091694. eCollection 2014. Erratum in: PLoS One. 2014;9(6):e100020. Fortt, Robin R [corrected to Fortt, R].

20.

A novel radiotracer to image glycogen metabolism in tumors by positron emission tomography.

Witney TH, Carroll L, Alam IS, Chandrashekran A, Nguyen QD, Sala R, Harris R, DeBerardinis RJ, Agarwal R, Aboagye EO.

Cancer Res. 2014 Mar 1;74(5):1319-28. doi: 10.1158/0008-5472.CAN-13-2768.

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