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Items: 1 to 50 of 118

1.

Author Correction: Novel Bead-Based Epitope Assay is a sensitive and reliable tool for profiling epitope-specific antibody repertoire in food allergy.

Suprun M, Getts R, Raghunathan R, Grishina G, Witmer M, Gimenez G, Sampson HA, Suárez-Fariñas M.

Sci Rep. 2020 Feb 13;10(1):2872. doi: 10.1038/s41598-020-58951-2.

2.

Novel Bead-Based Epitope Assay is a sensitive and reliable tool for profiling epitope-specific antibody repertoire in food allergy.

Suprun M, Getts R, Raghunathan R, Grishina G, Witmer M, Gimenez G, Sampson HA, Suárez-Fariñas M.

Sci Rep. 2019 Dec 5;9(1):18425. doi: 10.1038/s41598-019-54868-7. Erratum in: Sci Rep. 2020 Feb 13;10(1):2872.

3.

CYTOMEGALOVIRUS RETINITIS AFTER AN INTRAVITREAL DEXAMETHASONE IMPLANT IN AN IMMUNOCOMPETENT PATIENT.

Witmer MT, Connolly BP.

Retin Cases Brief Rep. 2019 Jul 17. doi: 10.1097/ICB.0000000000000904. [Epub ahead of print]

PMID:
31339873
4.

Structure-Property Basis for Solving Transporter-Mediated Efflux and Pan-Genotypic Inhibition in HCV NS5B Inhibitors.

Yeung KS, Beno BR, Mosure K, Zhu J, Grant-Young KA, Parcella K, Anjanappa P, Bora RO, Selvakumar K, Wang YK, Fang H, Krause R, Rigat K, Liu M, Lemm J, Sheriff S, Witmer M, Tredup J, Jardel A, Kish K, Parker D, Haskell R, Santone K, Meanwell NA, Soars MG, Roberts SB, Kadow JF.

ACS Med Chem Lett. 2018 Nov 5;9(12):1217-1222. doi: 10.1021/acsmedchemlett.8b00379. eCollection 2018 Dec 13.

5.

Treatment of Ipilimumab-Induced Vogt-Koyanagi-Harada Syndrome With Oral Dexamethasone.

Witmer MT.

Ophthalmic Surg Lasers Imaging Retina. 2017 Nov 1;48(11):928-931. doi: 10.3928/23258160-20171030-09.

PMID:
29121363
6.

An improved protocol for amino acid type-selective isotope labeling in insect cells.

Zhang Y, Wei H, Xie D, Calambur D, Douglas A, Gao M, Marsilio F, Metzler WJ, Szapiel N, Zhang P, Witmer MR, Mueller L, Hedin D.

J Biomol NMR. 2017 Aug;68(4):237-247. doi: 10.1007/s10858-017-0117-6. Epub 2017 Jul 15.

PMID:
28711957
7.

Discovery of a Hepatitis C Virus NS5B Replicase Palm Site Allosteric Inhibitor (BMS-929075) Advanced to Phase 1 Clinical Studies.

Yeung KS, Beno BR, Parcella K, Bender JA, Grant-Young KA, Nickel A, Gunaga P, Anjanappa P, Bora RO, Selvakumar K, Rigat K, Wang YK, Liu M, Lemm J, Mosure K, Sheriff S, Wan C, Witmer M, Kish K, Hanumegowda U, Zhuo X, Shu YZ, Parker D, Haskell R, Ng A, Gao Q, Colston E, Raybon J, Grasela DM, Santone K, Gao M, Meanwell NA, Sinz M, Soars MG, Knipe JO, Roberts SB, Kadow JF.

J Med Chem. 2017 May 25;60(10):4369-4385. doi: 10.1021/acs.jmedchem.7b00328. Epub 2017 May 4.

PMID:
28430437
8.

Primary Vitreoretinal Lymphoma: Management of Isolated Ocular Disease.

Witmer MT.

Cancer Control. 2016 Apr;23(2):110-6. Review.

PMID:
27218787
9.

Biotechnology Based Process for Production of a Disulfide-Bridged Peptide.

Goswami A, Goldberg SL, Hanson RL, Johnston RM, Lyngberg OK, Chan Y, Lo E, Chan SH, de Mas N, Ramirez A, Doyle R, Ding W, Gao M, Krystek SR Jr, Wan C, Kim YJ, Calambur D, Witmer M, Bryson JW.

Bioconjug Chem. 2016 May 18;27(5):1276-84. doi: 10.1021/acs.bioconjchem.6b00101. Epub 2016 May 2.

PMID:
27098672
10.

Development of a RapidFire mass spectrometry assay and a fluorescence assay for the discovery of kynurenine aminotransferase II inhibitors to treat central nervous system disorders.

Lu H, Kopcho L, Ghosh K, Witmer M, Parker M, Gupta S, Paul M, Krishnamurthy P, Laksmaiah B, Xie D, Tredup J, Zhang L, Abell LM.

Anal Biochem. 2016 May 15;501:56-65. doi: 10.1016/j.ab.2016.02.003. Epub 2016 Feb 11.

PMID:
26874021
11.

The HysNiche trial: hysteroscopic resection of uterine caesarean scar defect (niche) in patients with abnormal bleeding, a randomised controlled trial.

Vervoort AJ, Van der Voet LF, Witmer M, Thurkow AL, Radder CM, van Kesteren PJ, Quartero HW, Kuchenbecker WK, Bongers MY, Geomini PM, de Vleeschouwer LH, van Hooff MH, van Vliet HA, Veersema S, Renes WB, van Meurs HS, Bosmans J, Oude Rengerink K, Brölmann HA, Mol BW, Huirne JA.

BMC Womens Health. 2015 Nov 12;15:103. doi: 10.1186/s12905-015-0260-8.

12.

Polycystic Ovary Syndrome and Central Serous Chorioretinopathy.

Witmer MT, Klufas MA, Kiss S.

Ophthalmic Surg Lasers Imaging Retina. 2015 Jun;46(6):684-6. doi: 10.3928/23258160-20150610-16.

PMID:
26114853
13.

Tyrosine Kinase 2-mediated Signal Transduction in T Lymphocytes Is Blocked by Pharmacological Stabilization of Its Pseudokinase Domain.

Tokarski JS, Zupa-Fernandez A, Tredup JA, Pike K, Chang C, Xie D, Cheng L, Pedicord D, Muckelbauer J, Johnson SR, Wu S, Edavettal SC, Hong Y, Witmer MR, Elkin LL, Blat Y, Pitts WJ, Weinstein DS, Burke JR.

J Biol Chem. 2015 Apr 24;290(17):11061-74. doi: 10.1074/jbc.M114.619502. Epub 2015 Mar 11.

14.

Machines and cutters: Constellation®.

Witmer MT, Dugel PU.

Dev Ophthalmol. 2014;54:1-7. doi: 10.1159/000360442. Epub 2014 Aug 26. Review.

PMID:
25196745
15.

Reply: Niche risk factor for uterine rupture?

Bij de Vaate AJ, van der Voet LF, Naji O, Witmer M, Veersema S, Brölmann HA, Bourne T, Huirne JA.

Ultrasound Obstet Gynecol. 2014 Sep;44(3):371-2. doi: 10.1002/uog.14632. No abstract available.

16.

Quantitative measurement of ligand exchange on iron oxides via radiolabeled oleic acid.

Davis K, Qi B, Witmer M, Kitchens CL, Powell BA, Mefford OT.

Langmuir. 2014 Sep 16;30(36):10918-25. doi: 10.1021/la502204g. Epub 2014 Sep 2.

PMID:
25137089
17.

Central serous chorioretinopathy in patients receiving exogenous testosterone therapy.

Nudleman E, Witmer MT, Kiss S, Williams GA, Wolfe JD.

Retina. 2014 Oct;34(10):2128-32. doi: 10.1097/IAE.0000000000000198.

PMID:
24946102
18.

Pharmacologic profile of the Adnectin BMS-962476, a small protein biologic alternative to PCSK9 antibodies for low-density lipoprotein lowering.

Mitchell T, Chao G, Sitkoff D, Lo F, Monshizadegan H, Meyers D, Low S, Russo K, DiBella R, Denhez F, Gao M, Myers J, Duke G, Witmer M, Miao B, Ho SP, Khan J, Parker RA.

J Pharmacol Exp Ther. 2014 Aug;350(2):412-24. doi: 10.1124/jpet.114.214221. Epub 2014 Jun 10.

PMID:
24917546
19.

Characteristics of intraretinal deposits in acute central serous chorioretinopathy.

Plateroti AM, Witmer MT, Kiss S, D'Amico DJ.

Clin Ophthalmol. 2014 Apr 2;8:673-6. doi: 10.2147/OPTH.S48894. eCollection 2014. Review.

20.

High-throughput high-content imaging assays for identification and characterization of selective AXL pathway inhibitors.

Tang H, Yang J, Shen DR, Calambur D, Witmer M, Wu S, Carpenter B, Zhang Y, Gao M, Constantine K, Zhang L, Cvijic ME.

Assay Drug Dev Technol. 2014 Jan-Feb;12(1):80-6. doi: 10.1089/adt.2013.540.

PMID:
24547742
21.

Isolated foveal hypoplasia without nystagmus.

Giocanti-Aurégan A, Witmer MT, Radcliffe NM, D'Amico DJ.

Int Ophthalmol. 2014 Aug;34(4):877-80. doi: 10.1007/s10792-014-9900-5. Epub 2014 Jan 19.

PMID:
24442758
22.

Discovery and preclinical characterization of the cyclopropylindolobenzazepine BMS-791325, a potent allosteric inhibitor of the hepatitis C virus NS5B polymerase.

Gentles RG, Ding M, Bender JA, Bergstrom CP, Grant-Young K, Hewawasam P, Hudyma T, Martin S, Nickel A, Regueiro-Ren A, Tu Y, Yang Z, Yeung KS, Zheng X, Chao S, Sun JH, Beno BR, Camac DM, Chang CH, Gao M, Morin PE, Sheriff S, Tredup J, Wan J, Witmer MR, Xie D, Hanumegowda U, Knipe J, Mosure K, Santone KS, Parker DD, Zhuo X, Lemm J, Liu M, Pelosi L, Rigat K, Voss S, Wang Y, Wang YK, Colonno RJ, Gao M, Roberts SB, Gao Q, Ng A, Meanwell NA, Kadow JF.

J Med Chem. 2014 Mar 13;57(5):1855-79. doi: 10.1021/jm4016894. Epub 2014 Jan 7.

PMID:
24397558
23.

In vitro characterization of MK-1439, a novel HIV-1 nonnucleoside reverse transcriptase inhibitor.

Lai MT, Feng M, Falgueyret JP, Tawa P, Witmer M, DiStefano D, Li Y, Burch J, Sachs N, Lu M, Cauchon E, Campeau LC, Grobler J, Yan Y, Ducharme Y, Côté B, Asante-Appiah E, Hazuda DJ, Miller MD.

Antimicrob Agents Chemother. 2014;58(3):1652-63. doi: 10.1128/AAC.02403-13. Epub 2013 Dec 30.

24.

Spectrum of ocular manifestations in CLN2-associated batten (Jansky-Bielschowsky) disease correlate with advancing age and deteriorating neurological function.

Orlin A, Sondhi D, Witmer MT, Wessel MM, Mezey JG, Kaminsky SM, Hackett NR, Yohay K, Kosofsky B, Souweidane MM, Kaplitt MG, D'Amico DJ, Crystal RG, Kiss S.

PLoS One. 2013 Aug 28;8(8):e73128. doi: 10.1371/journal.pone.0073128. eCollection 2013.

25.

Prevalence, potential risk factors for development and symptoms related to the presence of uterine niches following Cesarean section: systematic review.

Bij de Vaate AJ, van der Voet LF, Naji O, Witmer M, Veersema S, Brölmann HA, Bourne T, Huirne JA.

Ultrasound Obstet Gynecol. 2014 Apr;43(4):372-82. doi: 10.1002/uog.13199. Review.

26.

The identification of novel p38α isoform selective kinase inhibitors having an unprecedented p38α binding mode.

Wrobleski ST, Lin S, Dhar TG, Dyckman AJ, Li T, Pitt S, Zhang R, Fan Y, Doweyko AM, Tokarski JS, Kish KF, Kiefer SE, Sack JS, Newitt JA, Witmer MR, McKinnon M, Barrish JC, Dodd JH, Schieven GL, Leftheris K.

Bioorg Med Chem Lett. 2013 Jul 15;23(14):4120-6. doi: 10.1016/j.bmcl.2013.05.047. Epub 2013 May 23.

PMID:
23746475
27.

The impact of color Doppler ultrasound on treatment patterns of epididymitis in a university-based healthcare system.

Smith RP, Tracy CR, Kavoussi PK, Witmer MT, Costabile RA.

Indian J Urol. 2013 Jan;29(1):22-6. doi: 10.4103/0970-1591.109979.

28.

Comparison of ultra-widefield fluorescein angiography with the Heidelberg Spectralis(®) noncontact ultra-widefield module versus the Optos(®) Optomap(®).

Witmer MT, Parlitsis G, Patel S, Kiss S.

Clin Ophthalmol. 2013;7:389-94. doi: 10.2147/OPTH.S41731. Epub 2013 Feb 21.

29.

Ophthalmic artery ischemic syndrome associated with neurofibromatosis and moyamoya syndrome.

Witmer MT, Levy R, Yohay K, Kiss S.

JAMA Ophthalmol. 2013 Apr;131(4):538-9. doi: 10.1001/jamaophthalmol.2013.2902. No abstract available.

PMID:
23430230
30.

Wide-field imaging of the retina.

Witmer MT, Kiss S.

Surv Ophthalmol. 2013 Mar-Apr;58(2):143-54. doi: 10.1016/j.survophthal.2012.07.003. Epub 2013 Jan 29. Review.

PMID:
23369515
31.

Oral anticoagulation and the risk of vitreous hemorrhage and retinal tears in eyes with acute posterior vitreous detachment.

Witmer MT, Cohen SM.

Retina. 2013 Mar;33(3):621-6. doi: 10.1097/IAE.0b013e3182671006.

PMID:
23108264
32.

Bilateral maculopathy associated with Pierre Robin sequence.

Witmer MT, Vasan R, Levy R, Davis J, Chan RV.

J AAPOS. 2012 Aug;16(4):409-10. doi: 10.1016/j.jaapos.2012.05.004.

PMID:
22929457
33.

Ultra-wide-field autofluorescence imaging in non-traumatic rhegmatogenous retinal detachment.

Witmer MT, Cho M, Favarone G, Chan RV, D'Amico DJ, Kiss S.

Eye (Lond). 2012 Sep;26(9):1209-16. doi: 10.1038/eye.2012.122. Epub 2012 Jun 22.

34.

Peripheral autofluorescence findings in age-related macular degeneration.

Witmer MT, Kozbial A, Daniel S, Kiss S.

Acta Ophthalmol. 2012 Sep;90(6):e428-33. doi: 10.1111/j.1755-3768.2012.02434.x. Epub 2012 May 11.

35.

Optical coherence tomography predicts visual outcome in macula-involving rhegmatogenous retinal detachment.

Cho M, Witmer MT, Favarone G, Chan RP, D'Amico DJ, Kiss S.

Clin Ophthalmol. 2012;6:91-6. doi: 10.2147/OPTH.S28173. Epub 2012 Jan 11.

36.

Emergency department eye care in Florida: a study of principal payer sources 2005 through 2009.

Witmer MT, Margo CE, Mulla ZD.

Arch Ophthalmol. 2012 Jan;130(1):25-32. doi: 10.1001/archophthalmol.2011.366.

PMID:
22232472
37.

Kyrieleis plaques associated with acute retinal necrosis from herpes simplex virus type 2.

Witmer MT, Levy-Clarke GA, Fouraker BD, Madow B.

Retin Cases Brief Rep. 2011 Fall;5(4):297-301. doi: 10.1097/ICB.0b013e3181f66aac.

PMID:
25390418
38.

Syntheses and initial evaluation of a series of indolo-fused heterocyclic inhibitors of the polymerase enzyme (NS5B) of the hepatitis C virus.

Zheng X, Hudyma TW, Martin SW, Bergstrom C, Ding M, He F, Romine J, Poss MA, Kadow JF, Chang CH, Wan J, Witmer MR, Morin P, Camac DM, Sheriff S, Beno BR, Rigat KL, Wang YK, Fridell R, Lemm J, Qiu D, Liu M, Voss S, Pelosi L, Roberts SB, Gao M, Knipe J, Gentles RG.

Bioorg Med Chem Lett. 2011 May 15;21(10):2925-9. doi: 10.1016/j.bmcl.2011.03.067. Epub 2011 Mar 23.

PMID:
21486696
39.

Investigation of the mode of binding of a novel series of N-benzyl-4-heteroaryl-1-(phenylsulfonyl)piperazine-2-carboxamides to the hepatitis C virus polymerase.

Gentles RG, Sheriff S, Beno BR, Wan C, Kish K, Ding M, Zheng X, Chupak L, Poss MA, Witmer MR, Morin P, Wang YK, Rigat K, Lemm J, Voss S, Liu M, Pelosi L, Roberts SB, Gao M, Kadow JF.

Bioorg Med Chem Lett. 2011 Apr 15;21(8):2212-5. doi: 10.1016/j.bmcl.2011.03.011. Epub 2011 Mar 6. Erratum in: Bioorg Med Chem Lett. 2011 Sep 15;21(18):5650-1.

PMID:
21441029
40.

Potent and selective HIV-1 ribonuclease H inhibitors based on a 1-hydroxy-1,8-naphthyridin-2(1H)-one scaffold.

Williams PD, Staas DD, Venkatraman S, Loughran HM, Ruzek RD, Booth TM, Lyle TA, Wai JS, Vacca JP, Feuston BP, Ecto LT, Flynn JA, DiStefano DJ, Hazuda DJ, Bahnck CM, Himmelberger AL, Dornadula G, Hrin RC, Stillmock KA, Witmer MV, Miller MD, Grobler JA.

Bioorg Med Chem Lett. 2010 Nov 15;20(22):6754-7. doi: 10.1016/j.bmcl.2010.08.135. Epub 2010 Sep 24.

PMID:
20869872
41.

Acute retinal necrosis associated optic neuropathy.

Witmer MT, Pavan PR, Fouraker BD, Levy-Clarke GA.

Acta Ophthalmol. 2011 Nov;89(7):599-607. doi: 10.1111/j.1755-3768.2010.01911.x. Epub 2010 Jul 20. Review.

42.

Tilted optic disks.

Witmer MT, Margo CE, Drucker M.

Surv Ophthalmol. 2010 Sep-Oct;55(5):403-28. doi: 10.1016/j.survophthal.2010.01.002. Epub 2010 Jul 10. Review.

PMID:
20621322
43.

Analysis of ophthalmology workforce and delivery of emergency department eye care in Florida.

Witmer MT, Margo CE.

Arch Ophthalmol. 2009 Nov;127(11):1522-7. doi: 10.1001/archophthalmol.2009.269.

PMID:
19901221
44.

Loss of raltegravir susceptibility by human immunodeficiency virus type 1 is conferred via multiple nonoverlapping genetic pathways.

Fransen S, Gupta S, Danovich R, Hazuda D, Miller M, Witmer M, Petropoulos CJ, Huang W.

J Virol. 2009 Nov;83(22):11440-6. doi: 10.1128/JVI.01168-09. Epub 2009 Sep 16.

45.

The relationship of intranasal steroids to intraocular pressure.

Bergmann J, Witmer MT, Slonim CB.

Curr Allergy Asthma Rep. 2009 Jul;9(4):311-5. Review.

PMID:
19656479
46.

Dissection of the endogenous cellular pathways of PCSK9-induced low density lipoprotein receptor degradation: evidence for an intracellular route.

Poirier S, Mayer G, Poupon V, McPherson PS, Desjardins R, Ly K, Asselin MC, Day R, Duclos FJ, Witmer M, Parker R, Prat A, Seidah NG.

J Biol Chem. 2009 Oct 16;284(42):28856-64. doi: 10.1074/jbc.M109.037085. Epub 2009 Jul 27.

47.

Long-term intraocular pressure control and corneal graft survival in eyes with a pars plana Baerveldt implant and corneal transplant.

Witmer MT, Tiedeman JS, Olsakovsky LA, Conaway MR, Prum BE.

J Glaucoma. 2010 Feb;19(2):124-31. doi: 10.1097/IJG.0b013e3181a98cc1.

PMID:
19528824
48.

Selection and analysis of HIV-1 integrase strand transfer inhibitor resistant mutant viruses.

Witmer M, Danovich R.

Methods. 2009 Apr;47(4):277-82. doi: 10.1016/j.ymeth.2009.02.025. Epub 2009 Mar 13.

PMID:
19286458
49.

A global benchmark study using affinity-based biosensors.

Rich RL, Papalia GA, Flynn PJ, Furneisen J, Quinn J, Klein JS, Katsamba PS, Waddell MB, Scott M, Thompson J, Berlier J, Corry S, Baltzinger M, Zeder-Lutz G, Schoenemann A, Clabbers A, Wieckowski S, Murphy MM, Page P, Ryan TE, Duffner J, Ganguly T, Corbin J, Gautam S, Anderluh G, Bavdek A, Reichmann D, Yadav SP, Hommema E, Pol E, Drake A, Klakamp S, Chapman T, Kernaghan D, Miller K, Schuman J, Lindquist K, Herlihy K, Murphy MB, Bohnsack R, Andrien B, Brandani P, Terwey D, Millican R, Darling RJ, Wang L, Carter Q, Dotzlaf J, Lopez-Sagaseta J, Campbell I, Torreri P, Hoos S, England P, Liu Y, Abdiche Y, Malashock D, Pinkerton A, Wong M, Lafer E, Hinck C, Thompson K, Primo CD, Joyce A, Brooks J, Torta F, Bagge Hagel AB, Krarup J, Pass J, Ferreira M, Shikov S, Mikolajczyk M, Abe Y, Barbato G, Giannetti AM, Krishnamoorthy G, Beusink B, Satpaev D, Tsang T, Fang E, Partridge J, Brohawn S, Horn J, Pritsch O, Obal G, Nilapwar S, Busby B, Gutierrez-Sanchez G, Gupta RD, Canepa S, Witte K, Nikolovska-Coleska Z, Cho YH, D'Agata R, Schlick K, Calvert R, Munoz EM, Hernaiz MJ, Bravman T, Dines M, Yang MH, Puskas A, Boni E, Li J, Wear M, Grinberg A, Baardsnes J, Dolezal O, Gainey M, Anderson H, Peng J, Lewis M, Spies P, Trinh Q, Bibikov S, Raymond J, Yousef M, Chandrasekaran V, Feng Y, Emerick A, Mundodo S, Guimaraes R, McGirr K, Li YJ, Hughes H, Mantz H, Skrabana R, Witmer M, Ballard J, Martin L, Skladal P, Korza G, Laird-Offringa I, Lee CS, Khadir A, Podlaski F, Neuner P, Rothacker J, Rafique A, Dankbar N, Kainz P, Gedig E, Vuyisich M, Boozer C, Ly N, Toews M, Uren A, Kalyuzhniy O, Lewis K, Chomey E, Pak BJ, Myszka DG.

Anal Biochem. 2009 Mar 15;386(2):194-216. doi: 10.1016/j.ab.2008.11.021. Epub 2008 Nov 27.

50.

Synthesis of 5-(1-H or 1-alkyl-5-oxopyrrolidin-3-yl)-8-hydroxy-[1,6]-naphthyridine-7-carboxamide inhibitors of HIV-1 integrase.

Melamed JY, Egbertson MS, Varga S, Vacca JP, Moyer G, Gabryelski L, Felock PJ, Stillmock KA, Witmer MV, Schleif W, Hazuda DJ, Leonard Y, Jin L, Ellis JD, Young SD.

Bioorg Med Chem Lett. 2008 Oct 1;18(19):5307-10. doi: 10.1016/j.bmcl.2008.08.038. Epub 2008 Aug 14.

PMID:
18774711

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