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T cells in IgA nephropathy: role in pathogenesis, clinical significance and potential therapeutic target.

Ruszkowski J, Lisowska KA, Pindel M, Heleniak Z, Dębska-Ślizień A, Witkowski JM.

Clin Exp Nephrol. 2018 Nov 7. doi: 10.1007/s10157-018-1665-0. [Epub ahead of print]


Direct Diagnostic Tests for Lyme Disease.

Schutzer SE, Body BA, Boyle J, Branson BM, Dattwyler RJ, Fikrig E, Gerald NJ, Gomes-Solecki M, Kintrup M, Ledizet M, Levin AE, Lewinski M, Liotta LA, Marques A, Mead PS, Mongodin EF, Pillai S, Rao P, Robinson WH, Roth KM, Schriefer ME, Slezak T, Snyder JL, Steere AC, Witkowski J, Wong SJ, Branda JA.

Clin Infect Dis. 2018 Oct 11. doi: 10.1093/cid/ciy614. [Epub ahead of print]


The integration of inflammaging in age-related diseases.

Fulop T, Witkowski JM, Olivieri F, Larbi A.

Semin Immunol. 2018 Oct 1. pii: S1044-5323(18)30022-8. doi: 10.1016/j.smim.2018.09.003. [Epub ahead of print] Review.


The level of cytokines in the vitreous body of severe proliferative diabetic retinopathy patients undergoing posterior vitrectomy.

Raczynska D, Lisowska KA, Pietruczuk K, Borucka J, Slizien M, Raczynska K, Glasner L, Witkowski JM.

Curr Pharm Des. 2018 Sep 26. doi: 10.2174/1381612824666180926110704. [Epub ahead of print]


A comparative clinical and functional assessment of cortical button versus suture anchor in distal biceps brachii tendon repair.

Reichert P, Królikowska A, Kentel M, Witkowski J, Gnus J, Satora W, Czamara A.

J Orthop Sci. 2018 Sep 12. pii: S0949-2658(18)30231-8. doi: 10.1016/j.jos.2018.08.007. [Epub ahead of print]


Can an Infection Hypothesis Explain the Beta Amyloid Hypothesis of Alzheimer's Disease?

Fulop T, Witkowski JM, Bourgade K, Khalil A, Zerif E, Larbi A, Hirokawa K, Pawelec G, Bocti C, Lacombe G, Dupuis G, Frost EH.

Front Aging Neurosci. 2018 Jul 24;10:224. doi: 10.3389/fnagi.2018.00224. eCollection 2018. Review.


Analysis of selected pro- and anti-inflammatory cytokines in patients with multiple injuries in the early period after trauma.

Gołąbek-Dropiewska K, Pawłowska J, Witkowski J, Lasek J, Marks W, Stasiak M, Jaskólski D, Kawecka A, Łuczkiewicz P, Baczkowski B.

Cent Eur J Immunol. 2018;43(1):42-49. doi: 10.5114/ceji.2018.74872. Epub 2018 Mar 30.


Proliferation and apoptosis of T lymphocytes in patients with bipolar disorder.

Pietruczuk K, Lisowska KA, Grabowski K, Landowski J, Witkowski JM.

Sci Rep. 2018 Feb 20;8(1):3327. doi: 10.1038/s41598-018-21769-0.


Surgical Management of Distal Biceps Tendon Anatomical Reinsertion Complications: Iatrogenic Posterior Interosseous Nerve Palsy.

Reichert P, Królikowska A, Witkowski J, Szuba Ł, Czamara A.

Med Sci Monit. 2018 Feb 7;24:782-790.


Immunosenescence and Inflamm-Aging As Two Sides of the Same Coin: Friends or Foes?

Fulop T, Larbi A, Dupuis G, Le Page A, Frost EH, Cohen AA, Witkowski JM, Franceschi C.

Front Immunol. 2018 Jan 10;8:1960. doi: 10.3389/fimmu.2017.01960. eCollection 2017. Review.


The significance of neonatal thymectomy for shaping the immune system in children with congenital heart defects.

Stosio M, Ruszkowski J, Mikosik-Roczyńska A, Haponiuk I, Witkowski JM.

Kardiochir Torakochirurgia Pol. 2017 Dec;14(4):258-262. doi: 10.5114/kitp.2017.72231. Epub 2017 Dec 20. Review.


Signal transduction changes in CD4+ and CD8+ T cell subpopulations with aging.

Le Page A, Dupuis G, Larbi A, Witkowski JM, Fülöp T.

Exp Gerontol. 2018 May;105:128-139. doi: 10.1016/j.exger.2018.01.005. Epub 2018 Jan 5.


Role of the peripheral innate immune system in the development of Alzheimer's disease.

Le Page A, Dupuis G, Frost EH, Larbi A, Pawelec G, Witkowski JM, Fulop T.

Exp Gerontol. 2018 Jul 1;107:59-66. doi: 10.1016/j.exger.2017.12.019. Epub 2017 Dec 21. Review.


Advances in Serodiagnostic Testing for Lyme Disease Are at Hand.

Branda JA, Body BA, Boyle J, Branson BM, Dattwyler RJ, Fikrig E, Gerald NJ, Gomes-Solecki M, Kintrup M, Ledizet M, Levin AE, Lewinski M, Liotta LA, Marques A, Mead PS, Mongodin EF, Pillai S, Rao P, Robinson WH, Roth KM, Schriefer ME, Slezak T, Snyder J, Steere AC, Witkowski J, Wong SJ, Schutzer SE.

Clin Infect Dis. 2018 Mar 19;66(7):1133-1139. doi: 10.1093/cid/cix943.


Autoantibodies, C-reactive protein, erythrocyte sedimentation rate and serum cytokine profiling in monitoring of early treatment.

Brzustewicz E, Henc I, Daca A, Szarecka M, Sochocka-Bykowska M, Witkowski J, Bryl E.

Cent Eur J Immunol. 2017;42(3):259-268. doi: 10.5114/ceji.2017.70968. Epub 2017 Oct 30.


Vitamin D status in patients with rheumatoid arthritis: a correlation analysis with disease activity and progression, as well as serum IL-6 levels.

Polasik K, Piotrowska E, Lipińska B, Witkowski JM, Bryl E, Tukaj S.

Acta Biochim Pol. 2017;64(4):667-670. doi: 10.18388/abp.2017_1636. Epub 2017 Dec 5.


Retrospective Evaluation of Surgical Anatomical Repair of Distal Biceps Brachii Tendon Rupture Using Suture Anchor Fixation.

Witkowski J, Królikowska A, Czamara A, Reichert P.

Med Sci Monit. 2017 Oct 17;23:4961-4972.


Proteodynamics in aging human T cells - The need for its comprehensive study to understand the fine regulation of T lymphocyte functions.

Witkowski JM, Mikosik A, Bryl E, Fulop T.

Exp Gerontol. 2018 Jul 1;107:161-168. doi: 10.1016/j.exger.2017.10.009. Epub 2017 Oct 13. Review.


Polymorphonuclear Neutrophil Functions are Differentially Altered in Amnestic Mild Cognitive Impairment and Mild Alzheimer's Disease Patients.

Le Page A, Lamoureux J, Bourgade K, Frost EH, Pawelec G, Witkowski JM, Larbi A, Dupuis G, Fülöp T.

J Alzheimers Dis. 2017;60(1):23-42. doi: 10.3233/JAD-170124.


Differential Phenotypes of Myeloid-Derived Suppressor and T Regulatory Cells and Cytokine Levels in Amnestic Mild Cognitive Impairment Subjects Compared to Mild Alzheimer Diseased Patients.

Le Page A, Garneau H, Dupuis G, Frost EH, Larbi A, Witkowski JM, Pawelec G, Fülöp T.

Front Immunol. 2017 Jul 7;8:783. doi: 10.3389/fimmu.2017.00783. eCollection 2017.


Computer-aided training sensorimotor cortex functions in humans before the upper limb transplantation using virtual reality and sensory feedback.

Kurzynski M, Jaskolska A, Marusiak J, Wolczowski A, Bierut P, Szumowski L, Witkowski J, Kisiel-Sajewicz K.

Comput Biol Med. 2017 Aug 1;87:311-321. doi: 10.1016/j.compbiomed.2017.06.010. Epub 2017 Jun 15.


Naturally occurring xanthone and benzophenone derivatives exert significant anti-proliferative and proapoptotic effects in vitro on synovial fibroblasts and macrophages from rheumatoid arthritis patients.

Henc I, Kokotkiewicz A, Łuczkiewicz P, Bryl E, Łuczkiewicz M, Witkowski JM.

Int Immunopharmacol. 2017 Aug;49:148-154. doi: 10.1016/j.intimp.2017.05.034. Epub 2017 Jun 3.


Heterogeneity of the cytokinome in undifferentiated arthritis progressing to rheumatoid arthritis and its change in the course of therapy. Move toward personalized medicine.

Brzustewicz E, Bzoma I, Daca A, Szarecka M, Bykowska MS, Witkowski JM, Bryl E.

Cytokine. 2017 Sep;97:1-13. doi: 10.1016/j.cyto.2017.05.012. Epub 2017 May 25.


Influence of oxygen concentration on T cell proliferation and susceptibility to apoptosis in healthy men and women.

Waskowska A, Lisowska KA, Daca A, Henc I, Brandberg F, Mazurek P, Brzustewicz E, Witkowski JM, Bryl E.

Folia Histochem Cytobiol. 2017;55(1):26-36. doi: 10.5603/FHC.a2017.0006.


What Is Dry Skin?

Parish LC, Witkowski JA, Lavery CJ.

Skinmed. 2016 Dec 1;14(6):409-411. eCollection 2016. No abstract available.


Cellular Senescence, Immunosenescence and HIV.

Fülöp T, Herbein G, Cossarizza A, Witkowski JM, Frost E, Dupuis G, Pawelec G, Larbi A.

Interdiscip Top Gerontol Geriatr. 2017;42:28-46. Epub 2016 Nov 22. Review.


Roles of calpain-calpastatin system (CCS) in human T cell activation.

Mikosik A, Jasiulewicz A, Daca A, Henc I, Frąckowiak JE, Ruckemann-Dziurdzińska K, Foerster J, Le Page A, Bryl E, Fulop T, Witkowski JM.

Oncotarget. 2016 Nov 22;7(47):76479-76495. doi: 10.18632/oncotarget.13259.


Phenotype, proliferation and apoptosis of B lymphocytes in hemodialysis patients treated with recombinant human erythropoietin.

Jasiulewicz A, Lisowska KA, Dębska-Ślizień A, Witkowski JM.

Int Immunol. 2016 Nov;28(11):523-532. Epub 2016 Jul 8.


Long-Term Results of Neurectomy Through a Dorsal Approach in the Treatment of Morton's Neuroma.

Reichert P, Zimmer K, Witkowski J, Wnukiewicz W, Kuliński S, Gosk J.

Adv Clin Exp Med. 2016 Mar-Apr;25(2):295-302. doi: 10.17219/acem/60249.


Intracellular signalling pathways: targets to reverse immunosenescence.

Fulop T, Witkowski JM, Le Page A, Fortin C, Pawelec G, Larbi A.

Clin Exp Immunol. 2017 Jan;187(1):35-43. doi: 10.1111/cei.12836. Epub 2016 Aug 3. Review.


The Role of Immunosenescence in the Development of Age-Related Diseases.

Fülöp T, Dupuis G, Witkowski JM, Larbi A.

Rev Invest Clin. 2016 Mar-Apr;68(2):84-91. Review.


Peripheral Immune Signatures in Alzheimer Disease.

Goldeck D, Witkowski JM, Fülop T, Pawelec G.

Curr Alzheimer Res. 2016;13(7):739-49. Review.


Causes of Secondary Radial Nerve Palsy and Results of Treatment.

Reichert P, Wnukiewicz W, Witkowski J, Bocheńska A, Mizia S, Gosk J, Zimmer K.

Med Sci Monit. 2016 Feb 19;22:554-62.


Protective Effect of Amyloid-β Peptides Against Herpes Simplex Virus-1 Infection in a Neuronal Cell Culture Model.

Bourgade K, Le Page A, Bocti C, Witkowski JM, Dupuis G, Frost EH, Fülöp T Jr.

J Alzheimers Dis. 2016;50(4):1227-41. doi: 10.3233/JAD-150652.


Polymers as Carriers of Gentamicin in Traumatology and Orthopedic Surgery - Current State Of Knowledge.

Witkowski J, Wnukiewicz W, Reichert P.

Polim Med. 2016 Jan-Jun;46(1):101-104. doi: 10.17219/pim/65053. Review.


Microbiome impact on metabolism and function of sex, thyroid, growth and parathyroid hormones.

Kunc M, Gabrych A, Witkowski JM.

Acta Biochim Pol. 2016;63(2):189-201. doi: 10.18388/abp.2015_1093. Epub 2015 Oct 26. Review.


From inflamm-aging to immune-paralysis: a slippery slope during aging for immune-adaptation.

Fulop T, Dupuis G, Baehl S, Le Page A, Bourgade K, Frost E, Witkowski JM, Pawelec G, Larbi A, Cunnane S.

Biogerontology. 2016 Feb;17(1):147-57. Review.


Increased μ-Calpain Activity in Blasts of Common B-Precursor Childhood Acute Lymphoblastic Leukemia Correlates with Their Lower Susceptibility to Apoptosis.

Mikosik A, Henc I, Ruckemann-Dziurdzińska K, Frąckowiak JE, Płoszyńska A, Balcerska A, Bryl E, Witkowski JM.

PLoS One. 2015 Aug 28;10(8):e0136615. doi: 10.1371/journal.pone.0136615. eCollection 2015. Erratum in: PLoS One. 2015;10(9):e0139063.


Frailty, Inflammation and Immunosenescence.

Fulop T, McElhaney J, Pawelec G, Cohen AA, Morais JA, Dupuis G, Baehl S, Camous X, Witkowski JM, Larbi A.

Interdiscip Top Gerontol Geriatr. 2015;41:26-40. doi: 10.1159/000381134. Epub 2015 Jul 17. Review.


Dexamethasone-dependent modulation of cyclic GMP synthesis in podocytes.

Lewko B, Waszkiewicz A, Maryn A, Gołos M, Latawiec E, Daca A, Witkowski JM, Angielski S, Stępiński J.

Mol Cell Biochem. 2015 Nov;409(1-2):243-53. doi: 10.1007/s11010-015-2528-6. Epub 2015 Aug 14.


Homeostatic 'bystander' proliferation of human peripheral blood B cells in response to polyclonal T-cell stimulation in vitro.

Jasiulewicz A, Lisowska KA, Pietruczuk K, Frąckowiak J, Fulop T, Witkowski JM.

Int Immunol. 2015 Nov;27(11):579-88. doi: 10.1093/intimm/dxv032. Epub 2015 May 20.


The high PMNs phagocytosis resistance of enterococcal isolates from RTx patients.

Jarzembowski T, Daca A, Witkowski JM, Bryl E, Rutkowski B.

Biomed Res Int. 2015;2015:432579. doi: 10.1155/2015/432579. Epub 2015 Mar 10.


The in vitro modulatory effect of TNFα on the mRNA expression and protein levels of zinc finger protein ZNF334 in CD4(+) lymphocytes of healthy people.

Henc I, Soroczyńska-Cybula M, Bryl E, Witkowski JM.

Acta Biochim Pol. 2015;62(1):113-7. Epub 2015 Mar 4.


NK Cells are Activated in Amnestic Mild Cognitive Impairment but not in Mild Alzheimer's Disease Patients.

Le Page A, Bourgade K, Lamoureux J, Frost E, Pawelec G, Larbi A, Witkowski JM, Dupuis G, Fülöp T.

J Alzheimers Dis. 2015;46(1):93-107. doi: 10.3233/JAD-143054.


Untangling taxonomic confusion and diversification patterns of the Streak-breasted Scimitar Babblers (Timaliidae: Pomatorhinus ruficollis complex) in southern Asia.

Reddy S, Sharief S, Yohe LR, Witkowski J, Hosner PA, Nyári ÁS, Moyle RG.

Mol Phylogenet Evol. 2015 Jan;82 Pt A:183-92. doi: 10.1016/j.ympev.2014.10.013. Epub 2014 Oct 27.


Redefining genomic privacy: trust and empowerment.

Erlich Y, Williams JB, Glazer D, Yocum K, Farahany N, Olson M, Narayanan A, Stein LD, Witkowski JA, Kain RC.

PLoS Biol. 2014 Nov 4;12(11):e1001983. doi: 10.1371/journal.pbio.1001983. eCollection 2014 Nov.


Effect of CPAP treatment for obstructive sleep apnea hypopnea syndrome on lipid profile: a meta-regression analysis.

Nadeem R, Singh M, Nida M, Kwon S, Sajid H, Witkowski J, Pahomov E, Shah K, Park W, Champeau D.

J Clin Sleep Med. 2014 Dec 15;10(12):1295-302. doi: 10.5664/jcsm.4282.


[Mechanisms of the immune system ageing and some age-associated diseases].

Witkowski JM.

Postepy Biochem. 2014;60(2):233-9. Review. Polish.


Prophages in enterococcal isolates from renal transplant recipients: renal failure etiologies promote selection of strains.

Daca A, Jarzembowski T, Witkowski JM, Bryl E, Rutkowski B, Dębska-Ślizień A.

Biomed Res Int. 2014;2014:514689. doi: 10.1155/2014/514689. Epub 2014 Jul 3.

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