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Items: 1 to 50 of 198

1.

Sidney Udenfriend.

Weissbach H, Witkop B.

Biogr Mem Natl Acad Sci. 2003;83:270-98. No abstract available.

PMID:
14983827
2.

Der unbekannte Paul Ehrlich.

Witkop B.

Dusseld Arb Gesch Med. 1998;13:39-57. German. No abstract available.

PMID:
11637098
3.

Paul Ehrlich and his Magic bullets--revisited.

Witkop B.

Proc Am Philos Soc. 1999 Dec;143(4):540-57. No abstract available.

PMID:
11624364
4.

Theodor Hermann Felix Wieland (5 June 1913-24 November 1995).

Witkop B, Eigen M.

Proc Am Philos Soc. 1998 Jun;142(2):317-9. No abstract available.

PMID:
11620079
5.

Peptides in health and disease: retrospection and outlook.

Witkop B.

Med Res Rev. 1992 May;12(3):275-96. Review. No abstract available.

PMID:
1578970
6.

Remembering Heinrich Wieland (1877-1957). Portrait of an organic chemist and founder of modern biochemistry.

Witkop B.

Med Res Rev. 1992 May;12(3):195-274. No abstract available. Erratum in: Med Res Rev 1992 Sep;12(5):563-4.

PMID:
1578969
7.

Retro-, intro- and perspectives of trypto-fun.

Witkop B.

Adv Exp Med Biol. 1991;294:3-13. Review. No abstract available.

PMID:
1663313
8.
9.

A study of the novel synthetic analog (+/-)-depentylperhydrohistrionicotoxin on the nicotinic receptor-ion channel complex.

Maleque MA, Takahashi K, Witkop B, Brossi A, Albuquerque EX.

J Pharmacol Exp Ther. 1984 Sep;230(3):619-26.

PMID:
6088758
10.

Interaction of analogs of histrionicotoxin with the acetylcholine receptor ionic channel complex and membrane excitability.

Maleque MA, Brossi A, Witkop B, Godleski SA, Albuquerque EX.

J Pharmacol Exp Ther. 1984 Apr;229(1):72-9.

PMID:
6323691
11.

Potencies and channel properties induced by semirigid agonists at frog nicotinic acetylcholine receptors.

Spivak CE, Waters J, Witkop B, Albuquerque EX.

Mol Pharmacol. 1983 Mar;23(2):337-43.

PMID:
6300643
12.

Electrophysiological and biochemical studies on enhancement of desensitization by phenothiazine neuroleptics.

Carp JS, Aronstam RS, Witkop B, Albuquerque EX.

Proc Natl Acad Sci U S A. 1983 Jan;80(1):310-4.

13.

(+/-)-2-Depentylperhydrohistrionicotoxin: a new probe for a regulatory site on the nicotinic acetylcholine receptor-channel.

Takahashi K, Jacobson AE, Mak CP, Witkop B, Brossi A, Albuquerque EX, Warnick JE, Maleque MA, Bavoso A, Silverton JV.

J Med Chem. 1982 Aug;25(8):919-25.

PMID:
6288946
14.

Differentiation of the open and closed states of the ionic channels of nicotinic acetylcholine receptors by tricyclic antidepressants.

Schofield GG, Witkop B, Warnick JE, Albuquerque EX.

Proc Natl Acad Sci U S A. 1981 Aug;78(8):5240-4.

15.

Anatoxin-a interactions with cholinergic synaptic molecules.

Aronstam RS, Witkop B.

Proc Natl Acad Sci U S A. 1981 Jul;78(7):4639-43.

17.

Anatoxin-a: a novel, potent agonist at the nicotinic receptor.

Spivak CE, Witkop B, Albuquerque EX.

Mol Pharmacol. 1980 Nov;18(3):384-94. No abstract available.

PMID:
6970328
18.

Phencyclidine interactions with the ionic channel of the acetylcholine receptor and electrogenic membrane.

Albuquerque EX, Tsai MC, Aronstam RS, Witkop B, Eldefrawi AT, Eldefrawi ME.

Proc Natl Acad Sci U S A. 1980 Feb;77(2):1224-8.

19.

Acetylcholine receptor and ionic channel of Torpedo electroplax: binding of perhydrohistrionicotoxin to membrane and solubilized preparations.

Eldefrawi ME, Eldefrawi AT, Mansour NA, Daly JW, Witkop B, Albuquerque EX.

Biochemistry. 1978 Dec 12;17(25):5474-84.

PMID:
728410
20.

Comparative binding studies with cholinergic ligands and histrionicotoxin at muscarinic receptors of neural cell lines.

Burgermeister W, Klein WL, Nirenberg M, Witkop B.

Mol Pharmacol. 1978 Sep;14(5):751-67. No abstract available.

PMID:
30889
21.

Antagonism of carbamylcholine-induced depolarization by batrachotoxin and veratridine.

Garrison DL, Albuquerque EX, Warnick JE, Daly JW, Witkop B.

Mol Pharmacol. 1978 Jan;14(1):111-21. No abstract available.

PMID:
304959
22.

Histrionicotoxin enhances agonist-induced desensitization of acetylcholine receptor.

Burgermeister W, Catterall WA, Witkop B.

Proc Natl Acad Sci U S A. 1977 Dec;74(12):5754-8.

23.

A valid model for the mechanism of oxidation of tryptophan to formylkynurenine-25 years later.

Nakagawa M, Watanabe H, Kodato S, Okajima H, Hino T, Flippen JL, Witkop B.

Proc Natl Acad Sci U S A. 1977 Nov;74(11):4730-3.

24.

Perhydrohistrionicotoxin: a potential ligand for the ion conductance modulator of the acetylcholine receptor.

Eldefrawi AT, Eldefrawi ME, Albuquerque EX, Oliveira AC, Mansour N, Adler M, Daly JW, Brown GB, Burgermeister W, Witkop B.

Proc Natl Acad Sci U S A. 1977 May;74(5):2172-6.

25.

Gephyrotoxins, histrionicotoxins and pumiliotoxins from the neotropical frog Dendrobates histrionicus.

Daly JW, Witkop B, Tokuyama T, Nishikawa T, Karle IL.

Helv Chim Acta. 1977 Apr 20;60(3):1128-40. No abstract available.

PMID:
863724
26.

The interaction of polyxanthylic acid with polyadenylic acid.

Torrence PF, De Clercq E, Witkop B.

Biochim Biophys Acta. 1977 Mar 2;475(1):1-6.

PMID:
849440
27.

Dependence of interferon induction on nucleic acid conformation.

Bobst AM, Torrence PF, Kouidou S, Witkop B.

Proc Natl Acad Sci U S A. 1976 Nov;73(11):3788-92.

28.

Antiviral activity of poly(7-deazainosinic acid)-derived complexes in vitro and in vivo.

Clercq ED, Edy VG, Torrence PF, Waters JA, Witkop B.

Mol Pharmacol. 1976 Nov;12(6):1045-51. No abstract available.

PMID:
1004489
29.

Conformation of uncomplexed [Phe4, Val6] antamanide crystallized from nonpolar solvents.

Karle IL, Karle J, Wieland T, Burgermeister W, Witkop B.

Proc Natl Acad Sci U S A. 1976 Jun;73(6):1782-5.

30.

Effect of cytosine, arabinoside, iododeoxyuridine, ethyldeoxyuridine, thiocyanatodeoxyuridine, and ribavirin on tail lesion formation in mice infected with vaccinia virus.

De Clercq E, Luczak M, Shugar D, Torrence PF, Waters JA, Witkop B.

Proc Soc Exp Biol Med. 1976 Mar;151(3):487-90.

PMID:
1257248
31.
32.

Polynucleotide displacement reactions: detection by interferon induction.

De Clercq E, Torrence PF, Witkop B.

Biochemistry. 1976 Feb 24;15(4):717-24.

PMID:
942856
33.

[Design of polynucleotides that act as inducers of interferon (author's transl)].

Torrence PF, Witkop B.

Tanpakushitsu Kakusan Koso. 1976;21(7):536-43. Review. Japanese. No abstract available.

PMID:
788048
34.

Antiviral and antimetabolic activities of poly (7-deazaadenylic acid) and poly (7-deazainosinic acid).

de Clercq E, Billiau A, Torrence PF, Waters JA, Witkop B.

Biochem Pharmacol. 1975 Dec 15;24(24):2233-8. No abstract available.

PMID:
175799
35.

Antiviral activity of 5-thiocyanatopyrimidine nucleosides.

De Clercq E, Torrence PF, Waters JA, Witkop B.

Biochem Pharmacol. 1975 Dec 1;24(23):2171-5. No abstract available.

PMID:
1239998
36.

Anti-complement activity of polynucleotides.

De Clercq E, Torrence PF, Hobbs J, Janik B, De Somer P, Witkop B.

Biochem Biophys Res Commun. 1975 Nov 3;67(1):255-63. No abstract available.

PMID:
1201021
37.

Structural features of double-stranded polyribonucleotides required for immunological specificity and interferon induction.

Johnston MI, Stollar BD, Torrence PF, Witkop B.

Proc Natl Acad Sci U S A. 1975 Nov;72(11):4564-8.

38.

Polynucleotide duplexes based on poly(7-deazaadenylic acid).

Torrence PF, Witkop B.

Biochim Biophys Acta. 1975 Jun 2;395(1):56-66.

PMID:
166696
39.

Effects of histrionicotoxin on the chemosensitive and electrical properties of skeletal muscle.

Lapa AJ, Albuquerque EX, Sarvey JM, Daly J, Witkop B.

Exp Neurol. 1975 Jun;47(3):558-80. No abstract available.

PMID:
1132464
40.
41.

The pharmacology of batrachotoxin. VII. Structure-activity relationships and the effects of pH.

Warnick JE, Albuquerque EX, Onur R, Jansson SE, Daly J, Tokuyama T, Witkop B.

J Pharmacol Exp Ther. 1975 Apr;193(1):232-45.

PMID:
237113
42.

Failure of duplexes based on polylaurusin (poly(L), "Polyformycin B") to induce interferon.

Torrence PF, De Clercq E, Waters JA, Witkop B.

Biochem Biophys Res Commun. 1975 Feb 3;62(3):658-64. No abstract available.

PMID:
1120073
43.

Inhibition of oncornavirus functions by 2'-azido polynucleotides.

De Clercq E, Billiau A, Hobbs J, Torrence PF, Witkop B.

Proc Natl Acad Sci U S A. 1975 Jan;72(1):284-8.

44.

Interferon induction: tool for establishing interactions among homopolyribonucleotides.

De Clercq E, Torrence PF, Witkop B, Stewart WE 2nd, De Somer P.

Science. 1974 Nov 29;186(4166):835-7.

PMID:
4469683
45.

The isolation and characterization of gamma-L-glutamyl-S-(trans-1-propenyl)-L-cysteine sulfoxide from sandal (Santalum album L). An interesting occurrence of sulfoxide diastereoisomers in nature.

Kuttan R, Nair NG, Radhakrishnan AN, Spande TF, Yeh HJ, Witkop B.

Biochemistry. 1974 Oct 8;13(21):4394-400. No abstract available.

PMID:
4416336
46.

A potent interferon inducer derived from poly (7-deazainosinic acid).

Torrence PF, De Clercq E, Waters JA, Witkop B.

Biochemistry. 1974 Oct 8;13(21):4400-8. No abstract available.

PMID:
4369728
47.

Proceedings: Inhibition of mouse leukemia virus RNA-dependent DNA polymerase by 2'-OH-substituted polynucleotides.

de Clercq E, Billiau A, Hobbs J, Torrence PF, Witkop B.

Hoppe Seylers Z Physiol Chem. 1974 Oct;355(10):1184. No abstract available.

PMID:
4142628
48.

A new, practical synthesis of L-2-hydroxytryptophan and its derivatives.

Ono M, Spande TF, Witkop B.

J Org Chem. 1974 Aug 23;39(17):2635-6. No abstract available.

PMID:
4547126
49.

2,4,5-Trimethylpyrrole-3-carboxylic acid esters of various alkaloids.

Waters JA, Creveling CR, Witkop B.

J Med Chem. 1974 May;17(5):488-91. No abstract available.

PMID:
4830250
50.

Photocyclizations of N-chloroacetyltyramine. I. Formation of novel dimeric cage compounds.

Iwakuma T, Nakai H, Yonemitsu O, Witkop B.

J Am Chem Soc. 1974 Apr 17;96(8):2564-9. No abstract available.

PMID:
4833709

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