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Items: 38


Pedigree-based estimation of human mobile element retrotransposition rates.

Feusier J, Watkins WS, Thomas J, Farrell A, Witherspoon DJ, Baird L, Ha H, Xing J, Jorde LB.

Genome Res. 2019 Oct;29(10):1567-1577. doi: 10.1101/gr.247965.118.


Discovery of rare, diagnostic AluYb8/9 elements in diverse human populations.

Feusier J, Witherspoon DJ, Scott Watkins W, Goubert C, Sasani TA, Jorde LB.

Mob DNA. 2017 Jul 27;8:9. doi: 10.1186/s13100-017-0093-0. eCollection 2017.


PADRE: Pedigree-Aware Distant-Relationship Estimation.

Staples J, Witherspoon DJ, Jorde LB, Nickerson DA; University of Washington Center for Mendelian Genomics, Below JE, Huff CD.

Am J Hum Genet. 2016 Jul 7;99(1):154-62. doi: 10.1016/j.ajhg.2016.05.020. Epub 2016 Jun 30.


Adaptive genetic changes related to haemoglobin concentration in native high-altitude Tibetans.

Simonson TS, Huff CD, Witherspoon DJ, Prchal JT, Jorde LB.

Exp Physiol. 2015 Nov;100(11):1263-8. doi: 10.1113/EP085035. Review.


Targeted Capture of Phylogenetically Informative Ves SINE Insertions in Genus Myotis.

Platt RN 2nd, Zhang Y, Witherspoon DJ, Xing J, Suh A, Keith MS, Jorde LB, Stevens RD, Ray DA.

Genome Biol Evol. 2015 May 25;7(6):1664-75. doi: 10.1093/gbe/evv099.


The heritability of gestational age in a two-million member cohort: implications for spontaneous preterm birth.

Wu W, Witherspoon DJ, Fraser A, Clark EA, Rogers A, Stoddard GJ, Manuck TA, Chen K, Esplin MS, Smith KR, Varner MW, Jorde LB.

Hum Genet. 2015 Jul;134(7):803-8. doi: 10.1007/s00439-015-1558-1. Epub 2015 Apr 29.


Shared and unique signals of high-altitude adaptation in geographically distinct Tibetan populations.

Wuren T, Simonson TS, Qin G, Xing J, Huff CD, Witherspoon DJ, Jorde LB, Ge RL.

PLoS One. 2014 Mar 18;9(3):e88252. doi: 10.1371/journal.pone.0088252. eCollection 2014.


Genomic analysis of natural selection and phenotypic variation in high-altitude mongolians.

Xing J, Wuren T, Simonson TS, Watkins WS, Witherspoon DJ, Wu W, Qin G, Huff CD, Jorde LB, Ge RL.

PLoS Genet. 2013;9(7):e1003634. doi: 10.1371/journal.pgen.1003634. Epub 2013 Jul 18.


Mobile element scanning (ME-Scan) identifies thousands of novel Alu insertions in diverse human populations.

Witherspoon DJ, Zhang Y, Xing J, Watkins WS, Ha H, Batzer MA, Jorde LB.

Genome Res. 2013 Jul;23(7):1170-81. doi: 10.1101/gr.148973.112. Epub 2013 Apr 18.


Mobile element biology: new possibilities with high-throughput sequencing.

Xing J, Witherspoon DJ, Jorde LB.

Trends Genet. 2013 May;29(5):280-9. doi: 10.1016/j.tig.2012.12.002. Epub 2013 Jan 9. Review.


Genetic analysis of ancestry, admixture and selection in Bolivian and Totonac populations of the New World.

Watkins WS, Xing J, Huff C, Witherspoon DJ, Zhang Y, Perego UA, Woodward SR, Jorde LB.

BMC Genet. 2012 May 20;13:39. doi: 10.1186/1471-2156-13-39.


Metabolic insight into mechanisms of high-altitude adaptation in Tibetans.

Ge RL, Simonson TS, Cooksey RC, Tanna U, Qin G, Huff CD, Witherspoon DJ, Xing J, Zhengzhong B, Prchal JT, Jorde LB, McClain DA.

Mol Genet Metab. 2012 Jun;106(2):244-7. doi: 10.1016/j.ymgme.2012.03.003. Epub 2012 Mar 17.


Crohn's disease and genetic hitchhiking at IBD5.

Huff CD, Witherspoon DJ, Zhang Y, Gatenbee C, Denson LA, Kugathasan S, Hakonarson H, Whiting A, Davis CT, Wu W, Xing J, Watkins WS, Bamshad MJ, Bradfield JP, Bulayeva K, Simonson TS, Jorde LB, Guthery SL.

Mol Biol Evol. 2012 Jan;29(1):101-11. doi: 10.1093/molbev/msr151. Epub 2011 Aug 4.


Maximum-likelihood estimation of recent shared ancestry (ERSA).

Huff CD, Witherspoon DJ, Simonson TS, Xing J, Watkins WS, Zhang Y, Tuohy TM, Neklason DW, Burt RW, Guthery SL, Woodward SR, Jorde LB.

Genome Res. 2011 May;21(5):768-74. doi: 10.1101/gr.115972.110. Epub 2011 Feb 8.


Ancestry of the Iban is predominantly Southeast Asian: genetic evidence from autosomal, mitochondrial, and Y chromosomes.

Simonson TS, Xing J, Barrett R, Jerah E, Loa P, Zhang Y, Watkins WS, Witherspoon DJ, Huff CD, Woodward S, Mowry B, Jorde LB.

PLoS One. 2011 Jan 31;6(1):e16338. doi: 10.1371/journal.pone.0016338.


Toward a more uniform sampling of human genetic diversity: a survey of worldwide populations by high-density genotyping.

Xing J, Watkins WS, Shlien A, Walker E, Huff CD, Witherspoon DJ, Zhang Y, Simonson TS, Weiss RB, Schiffman JD, Malkin D, Woodward SR, Jorde LB.

Genomics. 2010 Oct;96(4):199-210. doi: 10.1016/j.ygeno.2010.07.004. Epub 2010 Jul 16.


Mobile element scanning (ME-Scan) by targeted high-throughput sequencing.

Witherspoon DJ, Xing J, Zhang Y, Watkins WS, Batzer MA, Jorde LB.

BMC Genomics. 2010 Jun 30;11:410. doi: 10.1186/1471-2164-11-410.


Genetic evidence for high-altitude adaptation in Tibet.

Simonson TS, Yang Y, Huff CD, Yun H, Qin G, Witherspoon DJ, Bai Z, Lorenzo FR, Xing J, Jorde LB, Prchal JT, Ge R.

Science. 2010 Jul 2;329(5987):72-5. doi: 10.1126/science.1189406. Epub 2010 May 13.


Limited distribution of a cardiomyopathy-associated variant in India.

Simonson TS, Zhang Y, Huff CD, Xing J, Watkins WS, Witherspoon DJ, Woodward SR, Jorde LB.

Ann Hum Genet. 2010 Mar;74(2):184-8. doi: 10.1111/j.1469-1809.2010.00561.x. Epub 2010 Feb 18.


Alu repeats increase local recombination rates.

Witherspoon DJ, Watkins WS, Zhang Y, Xing J, Tolpinrud WL, Hedges DJ, Batzer MA, Jorde LB.

BMC Genomics. 2009 Nov 16;10:530. doi: 10.1186/1471-2164-10-530.


Fine-scaled human genetic structure revealed by SNP microarrays.

Xing J, Watkins WS, Witherspoon DJ, Zhang Y, Guthery SL, Thara R, Mowry BJ, Bulayeva K, Weiss RB, Jorde LB.

Genome Res. 2009 May;19(5):815-25. doi: 10.1101/gr.085589.108.


Estimating the age of retrotransposon subfamilies using maximum likelihood.

Marchani EE, Xing J, Witherspoon DJ, Jorde LB, Rogers AR.

Genomics. 2009 Jul;94(1):78-82. doi: 10.1016/j.ygeno.2009.04.002. Epub 2009 Apr 18.


Genetic variation in South Indian castes: evidence from Y-chromosome, mitochondrial, and autosomal polymorphisms.

Watkins WS, Thara R, Mowry BJ, Zhang Y, Witherspoon DJ, Tolpinrud W, Bamshad MJ, Tirupati S, Padmavati R, Smith H, Nancarrow D, Filippich C, Jorde LB.

BMC Genet. 2008 Dec 12;9:86. doi: 10.1186/1471-2156-9-86.


High fidelity of whole-genome amplified DNA on high-density single nucleotide polymorphism arrays.

Xing J, Watkins WS, Zhang Y, Witherspoon DJ, Jorde LB.

Genomics. 2008 Dec;92(6):452-6. doi: 10.1016/j.ygeno.2008.08.007. Epub 2008 Sep 27.


HapMap tagSNP transferability in multiple populations: general guidelines.

Xing J, Witherspoon DJ, Watkins WS, Zhang Y, Tolpinrud W, Jorde LB.

Genomics. 2008 Jul;92(1):41-51. doi: 10.1016/j.ygeno.2008.03.011. Epub 2008 May 14.


Mobile DNA elements in primate and human evolution.

Xing J, Witherspoon DJ, Ray DA, Batzer MA, Jorde LB.

Am J Phys Anthropol. 2007;Suppl 45:2-19. Review.


Genetic similarities within and between human populations.

Witherspoon DJ, Wooding S, Rogers AR, Marchani EE, Watkins WS, Batzer MA, Jorde LB.

Genetics. 2007 May;176(1):351-9. Epub 2007 Mar 4.


Human population genetic structure and diversity inferred from polymorphic L1(LINE-1) and Alu insertions.

Witherspoon DJ, Marchani EE, Watkins WS, Ostler CT, Wooding SP, Anders BA, Fowlkes JD, Boissinot S, Furano AV, Ray DA, Rogers AR, Batzer MA, Jorde LB.

Hum Hered. 2006;62(1):30-46. Epub 2006 Sep 21.


Modeling the amplification dynamics of human Alu retrotransposons.

Hedges DJ, Cordaux R, Xing J, Witherspoon DJ, Rogers AR, Jorde LB, Batzer MA.

PLoS Comput Biol. 2005 Sep;1(4):e44. Epub 2005 Sep 30.


Local adaptation and population differentiation at the interleukin 13 and interleukin 4 loci.

Sakagami T, Witherspoon DJ, Nakajima T, Jinnai N, Wooding S, Jorde LB, Hasegawa T, Suzuki E, Gejyo F, Inoue I.

Genes Immun. 2004 Aug;5(5):389-97.


Alu elements and hominid phylogenetics.

Salem AH, Ray DA, Xing J, Callinan PA, Myers JS, Hedges DJ, Garber RK, Witherspoon DJ, Jorde LB, Batzer MA.

Proc Natl Acad Sci U S A. 2003 Oct 28;100(22):12787-91. Epub 2003 Oct 15.


Selective constraints on P-element evolution.

Witherspoon DJ.

Mol Biol Evol. 1999 Apr;16(4):472-8.


Selection on the protein-coding genes of the TBE1 family of transposable elements in the ciliates Oxytricha fallax and O. trifallax.

Witherspoon DJ, Doak TG, Williams KR, Seegmiller A, Seger J, Herrick G.

Mol Biol Evol. 1997 Jul;14(7):696-706.


Conserved features of TBE1 transposons in ciliated protozoa.

Doak TG, Witherspoon DJ, Doerder FP, Williams K, Herrick G.

Genetica. 1997;101(2):75-86.


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