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Items: 41

1.

Prevalence and metric of depression and anxiety in systemic lupus erythematosus: A systematic review and meta-analysis.

Moustafa AT, Moazzami M, Engel L, Bangert E, Hassanein M, Marzouk S, Kravtsenyuk M, Fung W, Eder L, Su J, Wither JE, Touma Z.

Semin Arthritis Rheum. 2019 Jun 28. pii: S0049-0172(18)30563-8. doi: 10.1016/j.semarthrit.2019.06.017. [Epub ahead of print] Review.

PMID:
31303437
2.

Association of systemic lupus erythematosus (SLE) genetic susceptibility loci with lupus nephritis in childhood-onset and adult-onset SLE.

Webber D, Cao J, Dominguez D, Gladman DD, Levy DM, Ng L, Paterson AD, Touma Z, Urowitz MB, Wither JE, Silverman ED, Hiraki LT.

Rheumatology (Oxford). 2019 Jun 24. pii: kez220. doi: 10.1093/rheumatology/kez220. [Epub ahead of print]

PMID:
31236574
3.

A tyrosine sulfation-dependent HLA-I modification identifies memory B cells and plasma cells.

Chan JTH, Liu Y, Khan S, St-Germain JR, Zou C, Leung LYT, Yang J, Shi M, Grunebaum E, Campisi P, Propst EJ, Holler T, Bar-Or A, Wither JE, Cairo CW, Moran MF, Palazzo AF, Cooper MD, Ehrhardt GRA.

Sci Adv. 2018 Nov 7;4(11):eaar7653. doi: 10.1126/sciadv.aar7653. eCollection 2018 Nov.

4.

Identification of a neutrophil-related gene expression signature that is enriched in adult systemic lupus erythematosus patients with active nephritis: Clinical/pathologic associations and etiologic mechanisms.

Wither JE, Prokopec SD, Noamani B, Chang NH, Bonilla D, Touma Z, Avila-Casado C, Reich HN, Scholey J, Fortin PR, Boutros PC, Landolt-Marticorena C.

PLoS One. 2018 May 9;13(5):e0196117. doi: 10.1371/journal.pone.0196117. eCollection 2018.

5.

Genetic engineering in primary human B cells with CRISPR-Cas9 ribonucleoproteins.

Wu CM, Roth TL, Baglaenko Y, Ferri DM, Brauer P, Zuniga-Pflucker JC, Rosbe KW, Wither JE, Marson A, Allen CDC.

J Immunol Methods. 2018 Jun;457:33-40. doi: 10.1016/j.jim.2018.03.009. Epub 2018 Mar 31.

6.

Transancestral mapping and genetic load in systemic lupus erythematosus.

Langefeld CD, Ainsworth HC, Cunninghame Graham DS, Kelly JA, Comeau ME, Marion MC, Howard TD, Ramos PS, Croker JA, Morris DL, Sandling JK, Almlöf JC, Acevedo-Vásquez EM, Alarcón GS, Babini AM, Baca V, Bengtsson AA, Berbotto GA, Bijl M, Brown EE, Brunner HI, Cardiel MH, Catoggio L, Cervera R, Cucho-Venegas JM, Dahlqvist SR, D'Alfonso S, Da Silva BM, de la Rúa Figueroa I, Doria A, Edberg JC, Endreffy E, Esquivel-Valerio JA, Fortin PR, Freedman BI, Frostegård J, García MA, de la Torre IG, Gilkeson GS, Gladman DD, Gunnarsson I, Guthridge JM, Huggins JL, James JA, Kallenberg CGM, Kamen DL, Karp DR, Kaufman KM, Kottyan LC, Kovács L, Laustrup H, Lauwerys BR, Li QZ, Maradiaga-Ceceña MA, Martín J, McCune JM, McWilliams DR, Merrill JT, Miranda P, Moctezuma JF, Nath SK, Niewold TB, Orozco L, Ortego-Centeno N, Petri M, Pineau CA, Pons-Estel BA, Pope J, Raj P, Ramsey-Goldman R, Reveille JD, Russell LP, Sabio JM, Aguilar-Salinas CA, Scherbarth HR, Scorza R, Seldin MF, Sjöwall C, Svenungsson E, Thompson SD, Toloza SMA, Truedsson L, Tusié-Luna T, Vasconcelos C, Vilá LM, Wallace DJ, Weisman MH, Wither JE, Bhangale T, Oksenberg JR, Rioux JD, Gregersen PK, Syvänen AC, Rönnblom L, Criswell LA, Jacob CO, Sivils KL, Tsao BP, Schanberg LE, Behrens TW, Silverman ED, Alarcón-Riquelme ME, Kimberly RP, Harley JB, Wakeland EK, Graham RR, Gaffney PM, Vyse TJ.

Nat Commun. 2017 Jul 17;8:16021. doi: 10.1038/ncomms16021.

7.

Multiple tolerance defects contribute to the breach of B cell tolerance in New Zealand Black chromosome 1 congenic mice.

Chang NH, Manion KP, Loh C, Pau E, Baglaenko Y, Wither JE.

PLoS One. 2017 Jun 19;12(6):e0179506. doi: 10.1371/journal.pone.0179506. eCollection 2017.

8.

Invariant NKT Cell Activation Is Potentiated by Homotypic trans-Ly108 Interactions.

Baglaenko Y, Cruz Tleugabulova M, Gracey E, Talaei N, Manion KP, Chang NH, Ferri DM, Mallevaey T, Wither JE.

J Immunol. 2017 May 15;198(10):3949-3962. doi: 10.4049/jimmunol.1601369. Epub 2017 Apr 3.

9.

Development, Sensibility, and Validity of a Systemic Autoimmune Rheumatic Disease Case Ascertainment Tool.

Armstrong SM, Wither JE, Borowoy AM, Landolt-Marticorena C, Davis AM, Johnson SR.

J Rheumatol. 2017 Jan;44(1):18-23. doi: 10.3899/jrheum.160327. Epub 2016 Nov 1.

PMID:
27803141
10.

IL-10 Production Is Critical for Sustaining the Expansion of CD5+ B and NKT Cells and Restraining Autoantibody Production in Congenic Lupus-Prone Mice.

Baglaenko Y, Manion KP, Chang NH, Gracey E, Loh C, Wither JE.

PLoS One. 2016 Mar 10;11(3):e0150515. doi: 10.1371/journal.pone.0150515. eCollection 2016.

11.

Lack of Interferon and Proinflammatory Cyto/chemokines in Serologically Active Clinically Quiescent Systemic Lupus Erythematosus.

Steiman AJ, Gladman DD, Ibañez D, Noamani B, Landolt-Marticorena C, Urowitz MB, Wither JE.

J Rheumatol. 2015 Dec;42(12):2318-26. doi: 10.3899/jrheum.150040. Epub 2015 Nov 15.

PMID:
26568589
12.

Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus.

Bentham J, Morris DL, Graham DSC, Pinder CL, Tombleson P, Behrens TW, Martín J, Fairfax BP, Knight JC, Chen L, Replogle J, Syvänen AC, Rönnblom L, Graham RR, Wither JE, Rioux JD, Alarcón-Riquelme ME, Vyse TJ.

Nat Genet. 2015 Dec;47(12):1457-1464. doi: 10.1038/ng.3434. Epub 2015 Oct 26.

13.

Identification of the SLAM Adapter Molecule EAT-2 as a Lupus-Susceptibility Gene That Acts through Impaired Negative Regulation of Dendritic Cell Signaling.

Talaei N, Yu T, Manion K, Bremner R, Wither JE.

J Immunol. 2015 Nov 15;195(10):4623-31. doi: 10.4049/jimmunol.1500552. Epub 2015 Oct 2.

14.

Suppression of autoimmunity by CD5(+) IL-10-producing B cells in lupus-prone mice.

Baglaenko Y, Manion KP, Chang NH, Loh C, Lajoie G, Wither JE.

Genes Immun. 2015 Jul-Aug;16(5):311-20. doi: 10.1038/gene.2015.17. Epub 2015 May 14.

PMID:
25973757
15.

Interferon-α induces altered transitional B cell signaling and function in Systemic Lupus Erythematosus.

Chang NH, Li TT, Kim JJ, Landolt-Marticorena C, Fortin PR, Gladman DD, Urowitz MB, Wither JE.

J Autoimmun. 2015 Apr;58:100-10. doi: 10.1016/j.jaut.2015.01.009. Epub 2015 Feb 9.

PMID:
25678471
16.

Immunoglobulin G subclass analysis in psoriatic arthritis.

Haddad A, Thavaneswaran A, Abji F, Pellett F, Chandran V, Wither JE, Gladman DD.

J Rheumatol. 2014 Dec;41(12):2421-4. doi: 10.3899/jrheum.131477. Epub 2014 Oct 15.

PMID:
25320220
17.

Experimental evidence that mutated-self peptides derived from mitochondrial DNA somatic mutations have the potential to trigger autoimmunity.

Chen L, Duvvuri B, Grigull J, Jamnik R, Wither JE, Wu GE.

Hum Immunol. 2014 Aug;75(8):873-9. doi: 10.1016/j.humimm.2014.06.012. Epub 2014 Jun 28.

PMID:
24979674
18.

T cell and dendritic cell abnormalities synergize to expand pro-inflammatory T cell subsets leading to fatal autoimmunity in B6.NZBc1 lupus-prone mice.

Talaei N, Cheung YH, Landolt-Marticorena C, Noamani B, Li T, Wither JE.

PLoS One. 2013 Sep 20;8(9):e75166. doi: 10.1371/journal.pone.0075166. eCollection 2013.

19.

Identification of a lupus-susceptibility locus leading to impaired clearance of apoptotic debris on New Zealand Black chromosome 13.

Pau E, Loh C, Minty GE, Chang NH, Wither JE.

Genes Immun. 2013 Apr;14(3):154-61. doi: 10.1038/gene.2012.64. Epub 2013 Jan 17.

20.

TLR tolerance reduces IFN-alpha production despite plasmacytoid dendritic cell expansion and anti-nuclear antibodies in NZB bicongenic mice.

Pau E, Cheung YH, Loh C, Lajoie G, Wither JE.

PLoS One. 2012;7(5):e36761. doi: 10.1371/journal.pone.0036761. Epub 2012 May 4.

21.

Epistatic suppression of fatal autoimmunity in New Zealand black bicongenic mice.

Loh C, Pau E, Lajoie G, Li TT, Baglaenko Y, Cheung YH, Chang NH, Wither JE.

J Immunol. 2011 May 15;186(10):5845-53. doi: 10.4049/jimmunol.1003426. Epub 2011 Apr 4.

22.

Abrogation of pathogenic IgG autoantibody production in CD40L gene-deleted lupus-prone New Zealand Black mice.

Pau E, Chang NH, Loh C, Lajoie G, Wither JE.

Clin Immunol. 2011 May;139(2):215-27. doi: 10.1016/j.clim.2011.02.005. Epub 2011 Mar 17.

PMID:
21414847
23.

The lupus phenotype in B6.NZBc1 congenic mice reflects interactions between multiple susceptibility loci and a suppressor locus.

Cheung YH, Landolt-Marticorena C, Lajoie G, Wither JE.

Genes Immun. 2011 Jun;12(4):251-62. doi: 10.1038/gene.2010.71. Epub 2011 Feb 10.

PMID:
21307879
24.

An intrinsic B-cell defect supports autoimmunity in New Zealand black chromosome 13 congenic mice.

Loh C, Pau E, Chang NH, Wither JE.

Eur J Immunol. 2011 Feb;41(2):527-36. doi: 10.1002/eji.201040983. Epub 2010 Dec 29.

25.

Healthcare cost and loss of productivity in a Canadian population of patients with and without lupus nephritis.

Aghdassi E, Zhang W, St-Pierre Y, Clarke AE, Morrison S, Peeva V, Landolt-Marticorena C, Su J, Reich H, Scholey J, Herzenberg A, Pope JE, Peschken C; LuNNET CaNIOS Investigators, Wither JE, Fortin PR.

J Rheumatol. 2011 Apr;38(4):658-66. doi: 10.3899/jrheum.100482. Epub 2010 Dec 15.

PMID:
21159829
26.

Altered expression of TNF-alpha signaling pathway proteins in systemic lupus erythematosus.

Zhu LJ, Landolt-Marticorena C, Li T, Yang X, Yu XQ, Gladman DD, Urowitz MB, Fortin PR, Wither JE.

J Rheumatol. 2010 Aug 1;37(8):1658-66. doi: 10.3899/jrheum.091123. Epub 2010 Jun 1.

PMID:
20516030
27.

Bone marrow-derived human hematopoietic stem cells engraft NOD/SCID mice and traffic appropriately to an inflammatory stimulus in the joint.

Chang NH, Inman RD, Dick JE, Wither JE.

J Rheumatol. 2010 Mar;37(3):496-502. doi: 10.3899/jrheum.090317. Epub 2010 Jan 28.

PMID:
20110518
28.

Genetic variants near TNFAIP3 on 6q23 are associated with systemic lupus erythematosus.

Graham RR, Cotsapas C, Davies L, Hackett R, Lessard CJ, Leon JM, Burtt NP, Guiducci C, Parkin M, Gates C, Plenge RM, Behrens TW, Wither JE, Rioux JD, Fortin PR, Graham DC, Wong AK, Vyse TJ, Daly MJ, Altshuler D, Moser KL, Gaffney PM.

Nat Genet. 2008 Sep;40(9):1059-61. doi: 10.1038/ng.200.

29.

Common variants in the NLRP3 region contribute to Crohn's disease susceptibility.

Villani AC, Lemire M, Fortin G, Louis E, Silverberg MS, Collette C, Baba N, Libioulle C, Belaiche J, Bitton A, Gaudet D, Cohen A, Langelier D, Fortin PR, Wither JE, Sarfati M, Rutgeerts P, Rioux JD, Vermeire S, Hudson TJ, Franchimont D.

Nat Genet. 2009 Jan;41(1):71-6. doi: 10.1038/ng.285. Epub 2008 Dec 21.

30.

Expanded population of activated antigen-engaged cells within the naive B cell compartment of patients with systemic lupus erythematosus.

Chang NH, McKenzie T, Bonventi G, Landolt-Marticorena C, Fortin PR, Gladman D, Urowitz M, Wither JE.

J Immunol. 2008 Jan 15;180(2):1276-84.

31.

Immune mechanisms leading to abnormal B cell selection and activation in New Zealand Black mice.

Roy V, Bonventi G, Cai Y, Macleod R, Wither JE.

Eur J Immunol. 2007 Sep;37(9):2645-56.

33.
35.

Molecular basis of antigen recognition by insulin specific T cell receptor.

Sugiyama S, Kohyama M, Oda M, Azuma T, Wither JE, Hozumi N.

Immunol Lett. 2004 Feb 15;91(2-3):133-9.

PMID:
15019281
37.

Functional dissection of lupus susceptibility loci on the New Zealand black mouse chromosome 1: evidence for independent genetic loci affecting T and B cell activation.

Wither JE, Lajoie G, Heinrichs S, Cai YC, Chang N, Ciofani A, Cheung YH, MacLeod R.

J Immunol. 2003 Aug 15;171(4):1697-706.

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