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Items: 1 to 50 of 179


Funding and planning for social care in later life: a deliberative focus group study.

Dixon J, Trathen A, Wittenberg R, Mays N, Wistow G, Knapp M.

Health Soc Care Community. 2019 Jun 14. doi: 10.1111/hsc.12768. [Epub ahead of print]


Measuring Ultra-Weak Protein Self-Association by Non-ideal Sedimentation Velocity.

Chaturvedi SK, Sagar V, Zhao H, Wistow G, Schuck P.

J Am Chem Soc. 2019 Feb 20;141(7):2990-2996. doi: 10.1021/jacs.8b11371. Epub 2019 Feb 6.


Correlation of phenotype with genotype and protein structure in RYR1-related disorders.

Todd JJ, Sagar V, Lawal TA, Allen C, Razaqyar MS, Shelton MS, Chrismer IC, Zhang X, Cosgrove MM, Kuo A, Vasavada R, Jain MS, Waite M, Rajapakse D, Witherspoon JW, Wistow G, Meilleur KG.

J Neurol. 2018 Nov;265(11):2506-2524. doi: 10.1007/s00415-018-9033-2. Epub 2018 Aug 28.


The SUSTAIN Project: A European Study on Improving Integrated Care for Older People Living at Home.

de Bruin SR, Stoop A, Billings J, Leichsenring K, Ruppe G, Tram N, Barbaglia MG, Ambugo EA, Zonneveld N, Paat-Ahi G, Hoffmann H, Khan U, Stein V, Wistow G, Lette M, Jansen APD, Nijpels G, Baan CA; SUSTAIN consortium.

Int J Integr Care. 2018 Jan 16;18(1):6. doi: 10.5334/ijic.3090.


The klotho-related protein KLPH (lctl) has preferred expression in lens and is essential for expression of clic5 and normal lens suture formation.

Fan J, Lerner J, Wyatt MK, Cai P, Peterson K, Dong L, Wistow G.

Exp Eye Res. 2018 Apr;169:111-121. doi: 10.1016/j.exer.2018.02.001. Epub 2018 Feb 7.


Serum starvation of ARPE-19 changes the cellular distribution of cholesterol and Fibulin3 in patterns reminiscent of age-related macular degeneration.

Rajapakse D, Peterson K, Mishra S, Wistow G.

Exp Cell Res. 2017 Dec 15;361(2):333-341. doi: 10.1016/j.yexcr.2017.10.036. Epub 2017 Oct 31.


Crystal Structure of Chicken γS-Crystallin Reveals Lattice Contacts with Implications for Function in the Lens and the Evolution of the βγ-Crystallins.

Sagar V, Chaturvedi SK, Schuck P, Wistow G.

Structure. 2017 Jul 5;25(7):1068-1078.e2. doi: 10.1016/j.str.2017.05.015. Epub 2017 Jun 22.


Maturation arrest in early postnatal sensory receptors by deletion of the miR-183/96/182 cluster in mouse.

Fan J, Jia L, Li Y, Ebrahim S, May-Simera H, Wood A, Morell RJ, Liu P, Lei J, Kachar B, Belluscio L, Qian H, Li T, Li W, Wistow G, Dong L.

Proc Natl Acad Sci U S A. 2017 May 23;114(21):E4271-E4280. doi: 10.1073/pnas.1619442114. Epub 2017 May 8.


Accumulation of cholesterol and increased demand for zinc in serum-deprived RPE cells.

Mishra S, Peterson K, Yin L, Berger A, Fan J, Wistow G.

Mol Vis. 2016 Dec 10;22:1387-1404. eCollection 2016.


Costs and economic consequences of a help-at-home scheme for older people in England.

Bauer A, Knapp M, Wistow G, Perkins M, King D, Iemmi V.

Health Soc Care Community. 2017 Mar;25(2):780-789. doi: 10.1111/hsc.12372. Epub 2016 Jul 11.


Circles of Support and personalization: Exploring the economic case.

Wistow G, Perkins M, Knapp M, Bauer A, Bonin EM.

J Intellect Disabil. 2016 Jun;20(2):194-207. doi: 10.1177/1744629516637997. Epub 2016 Mar 22.


γ-Crystallins of the chicken lens: remnants of an ancient vertebrate gene family in birds.

Chen Y, Sagar V, Len HS, Peterson K, Fan J, Mishra S, McMurtry J, Wilmarth PA, David LL, Wistow G.

FEBS J. 2016 Apr;283(8):1516-30. doi: 10.1111/febs.13689. Epub 2016 Mar 11.


Editorial for special issue: crystallins of the eye.

Wistow GJ, Slingsby C.

Prog Biophys Mol Biol. 2014 Jul;115(1):1-2. doi: 10.1016/j.pbiomolbio.2014.05.003. Epub 2014 May 15. No abstract available.


Functions of crystallins in and out of lens: roles in elongated and post-mitotic cells.

Slingsby C, Wistow GJ.

Prog Biophys Mol Biol. 2014 Jul;115(1):52-67. doi: 10.1016/j.pbiomolbio.2014.02.006. Epub 2014 Feb 28. Review.


Reducing emergency bed-days for older people? Network governance lessons from the 'Improving the Future for Older People' programme.

Sheaff R, Windle K, Wistow G, Ashby S, Beech R, Dickinson A, Henderson C, Knapp M.

Soc Sci Med. 2014 Apr;106:59-66. doi: 10.1016/j.socscimed.2014.01.033. Epub 2014 Jan 30.


Solution properties of γ-crystallins: hydration of fish and mammal γ-crystallins.

Zhao H, Chen Y, Rezabkova L, Wu Z, Wistow G, Schuck P.

Protein Sci. 2014 Jan;23(1):88-99. doi: 10.1002/pro.2394. Epub 2013 Nov 27.


Solution properties of γ-crystallins: compact structure and low frictional ratio are conserved properties of diverse γ-crystallins.

Chen Y, Zhao H, Schuck P, Wistow G.

Protein Sci. 2014 Jan;23(1):76-87. doi: 10.1002/pro.2395. Epub 2013 Nov 28.


Interaction of complement factor h and fibulin3 in age-related macular degeneration.

Wyatt MK, Tsai JY, Mishra S, Campos M, Jaworski C, Fariss RN, Bernstein SL, Wistow G.

PLoS One. 2013 Jun 28;8(6):e68088. doi: 10.1371/journal.pone.0068088. Print 2013.


Does integrated governance lead to integrated patient care? Findings from the innovation forum.

Beech R, Henderson C, Ashby S, Dickinson A, Sheaff R, Windle K, Wistow G, Knapp M.

Health Soc Care Community. 2013 Nov;21(6):598-605. doi: 10.1111/hsc.12042. Epub 2013 May 3.


Structure and dynamics of the fish eye lens protein, γM7-crystallin.

Mahler B, Chen Y, Ford J, Thiel C, Wistow G, Wu Z.

Biochemistry. 2013 May 21;52(20):3579-87. doi: 10.1021/bi400151c. Epub 2013 May 8.


Evolution of crystallins for a role in the vertebrate eye lens.

Slingsby C, Wistow GJ, Clark AR.

Protein Sci. 2013 Apr;22(4):367-80. doi: 10.1002/pro.2229. Epub 2013 Feb 26. Review.


Integration: work still in progress.

Wistow G, Dickinson H.

J Health Organ Manag. 2012;26(6):676-84.


The human crystallin gene families.

Wistow G.

Hum Genomics. 2012 Dec 1;6:26. doi: 10.1186/1479-7364-6-26. Review.


A role for γS-crystallin in the organization of actin and fiber cell maturation in the mouse lens.

Fan J, Dong L, Mishra S, Chen Y, FitzGerald P, Wistow G.

FEBS J. 2012 Aug;279(16):2892-904. doi: 10.1111/j.1742-4658.2012.08669.x. Epub 2012 Jul 10.


Characterization of a transient unfolding intermediate in a core mutant of γS-crystallin.

Mahler B, Doddapaneni K, Kleckner I, Yuan C, Wistow G, Wu Z.

J Mol Biol. 2011 Jan 21;405(3):840-50. doi: 10.1016/j.jmb.2010.11.005. Epub 2010 Nov 23.


A single destabilizing mutation (F9S) promotes concerted unfolding of an entire globular domain in gammaS-crystallin.

Lee S, Mahler B, Toward J, Jones B, Wyatt K, Dong L, Wistow G, Wu Z.

J Mol Biol. 2010 Jun 4;399(2):320-30. doi: 10.1016/j.jmb.2010.04.003. Epub 2010 Apr 9.


Expression analysis of human pterygium shows a predominance of conjunctival and limbal markers and genes associated with cell migration.

Jaworski CJ, Aryankalayil-John M, Campos MM, Fariss RN, Rowsey J, Agarwalla N, Reid TW, Dushku N, Cox CA, Carper D, Wistow G.

Mol Vis. 2009 Nov 20;15:2421-34.


Expressed sequence tag analysis of adult human optic nerve for NEIBank: identification of cell type and tissue markers.

Bernstein SL, Guo Y, Peterson K, Wistow G.

BMC Neurosci. 2009 Sep 24;10:121. doi: 10.1186/1471-2202-10-121.


Expressed sequence tag analysis of guinea pig (Cavia porcellus) eye tissues for NEIBank.

Simpanya MF, Wistow G, Gao J, David LL, Giblin FJ, Mitton KP.

Mol Vis. 2008;14:2413-27. Epub 2008 Dec 19.


NEIBank: genomics and bioinformatics resources for vision research.

Wistow G, Peterson K, Gao J, Buchoff P, Jaworski C, Bowes-Rickman C, Ebright JN, Hauser MA, Hoover D.

Mol Vis. 2008 Jul 18;14:1327-37.


Exploring the limits of sequence and structure in a variant betagamma-crystallin domain of the protein absent in melanoma-1 (AIM1).

Aravind P, Wistow G, Sharma Y, Sankaranarayanan R.

J Mol Biol. 2008 Sep 5;381(3):509-18. doi: 10.1016/j.jmb.2008.06.019. Epub 2008 Jun 14.


Lengsin expression and function during zebrafish lens formation.

Harding RL, Howley S, Baker LJ, Murphy TR, Archer WE, Wistow G, Hyde DR, Vihtelic TS.

Exp Eye Res. 2008 May;86(5):807-18. doi: 10.1016/j.exer.2008.02.009. Epub 2008 Mar 2.


A role for lengsin, a recruited enzyme, in terminal differentiation in the vertebrate lens.

Wyatt K, Gao C, Tsai JY, Fariss RN, Ray S, Wistow G.

J Biol Chem. 2008 Mar 7;283(10):6607-15. doi: 10.1074/jbc.M709144200. Epub 2008 Jan 3.


Biophysical properties of gammaC-crystallin in human and mouse eye lens: the role of molecular dipoles.

Purkiss AG, Bateman OA, Wyatt K, Wilmarth PA, David LL, Wistow GJ, Slingsby C.

J Mol Biol. 2007 Sep 7;372(1):205-22. Epub 2007 Jun 26.


Development of a microarray chip for gene expression in rabbit ocular research.

Popp MP, Liu L, Timmers A, Esson DW, Shiroma L, Meyers C, Berceli S, Tao M, Wistow G, Schultz GS, Sherwood MB.

Mol Vis. 2007 Feb 2;13:164-73.


Endogenous retroviral insertion in Cryge in the mouse No3 cataract mutant.

Nag N, Peterson K, Wyatt K, Hess S, Ray S, Favor J, Bogani D, Lyon M, Wistow G.

Genomics. 2007 Apr;89(4):512-20. Epub 2007 Jan 12.


Lengsin is a survivor of an ancient family of class I glutamine synthetases re-engineered by evolution for a role in the vertebrate lens.

Wyatt K, White HE, Wang L, Bateman OA, Slingsby C, Orlova EV, Wistow G.

Structure. 2006 Dec;14(12):1823-34.


Governance and public involvement in the British National Health Service: understanding difficulties and developments.

Callaghan G, Wistow G.

Soc Sci Med. 2006 Nov;63(9):2289-300. Epub 2006 Jul 31.


Defining the human macula transcriptome and candidate retinal disease genes using EyeSAGE.

Bowes Rickman C, Ebright JN, Zavodni ZJ, Yu L, Wang T, Daiger SP, Wistow G, Boon K, Hauser MA.

Invest Ophthalmol Vis Sci. 2006 Jun;47(6):2305-16.


Gene duplication and separation of functions in alphaB-crystallin from zebrafish (Danio rerio).

Smith AA, Wyatt K, Vacha J, Vihtelic TS, Zigler JS Jr, Wistow GJ, Posner M.

FEBS J. 2006 Feb;273(3):481-90.


Expressed sequence tag analysis of zebrafish eye tissues for NEIBank.

Vihtelic TS, Fadool JM, Gao J, Thornton KA, Hyde DR, Wistow G.

Mol Vis. 2005 Dec 13;11:1083-100.


Solution structure of (gamma)S-crystallin by molecular fragment replacement NMR.

Wu Z, Delaglio F, Wyatt K, Wistow G, Bax A.

Protein Sci. 2005 Dec;14(12):3101-14. Epub 2005 Oct 31.


The NEIBank project for ocular genomics: data-mining gene expression in human and rodent eye tissues.

Wistow G.

Prog Retin Eye Res. 2006 Jan;25(1):43-77. Epub 2005 Jul 7. Review.


gammaN-crystallin and the evolution of the betagamma-crystallin superfamily in vertebrates.

Wistow G, Wyatt K, David L, Gao C, Bateman O, Bernstein S, Tomarev S, Segovia L, Slingsby C, Vihtelic T.

FEBS J. 2005 May;272(9):2276-91.


The lacrimal gland transcriptome is an unusually rich source of rare and poorly characterized gene transcripts.

Ozyildirim AM, Wistow GJ, Gao J, Wang J, Dickinson DP, Frierson HF Jr, Laurie GW.

Invest Ophthalmol Vis Sci. 2005 May;46(5):1572-80.


Specific interaction between lens MIP/Aquaporin-0 and two members of the gamma-crystallin family.

Fan J, Fariss RN, Purkiss AG, Slingsby C, Sandilands A, Quinlan R, Wistow G, Chepelinsky AB.

Mol Vis. 2005 Jan 25;11:76-87. Erratum in: Mol Vis. 2005 Jan 25;11: 1 p following 87.


Platelet-derived growth factor D, tissue-specific expression in the eye, and a key role in control of lens epithelial cell proliferation.

Ray S, Gao C, Wyatt K, Fariss RN, Bundek A, Zelenka P, Wistow G.

J Biol Chem. 2005 Mar 4;280(9):8494-502. Epub 2004 Dec 16.


The P23T cataract mutation causes loss of solubility of folded gammaD-crystallin.

Evans P, Wyatt K, Wistow GJ, Bateman OA, Wallace BA, Slingsby C.

J Mol Biol. 2004 Oct 15;343(2):435-44.


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