Sort by
Items per page

Send to

Choose Destination

Search results

Items: 36


Proteomic Pathway Analysis of Monocyte-Derived Exosomes during Surgical Sepsis Identifies Immunoregulatory Functions.

Wisler JR, Singh K, Mccarty AR, Abouhashem ASE, Christman JW, Sen CK.

Surg Infect (Larchmt). 2019 Sep 11. doi: 10.1089/sur.2019.051. [Epub ahead of print]


β-arrestin 1 regulates β2-adrenergic receptor-mediated skeletal muscle hypertrophy and contractility.

Kim J, Grotegut CA, Wisler JW, Li T, Mao L, Chen M, Chen W, Rosenberg PB, Rockman HA, Lefkowitz RJ.

Skelet Muscle. 2018 Dec 27;8(1):39. doi: 10.1186/s13395-018-0184-8.


Repurposing isoxazoline veterinary drugs for control of vector-borne human diseases.

Miglianico M, Eldering M, Slater H, Ferguson N, Ambrose P, Lees RS, Koolen KMJ, Pruzinova K, Jancarova M, Volf P, Koenraadt CJM, Duerr HP, Trevitt G, Yang B, Chatterjee AK, Wisler J, Sturm A, Bousema T, Sauerwein RW, Schultz PG, Tremblay MS, Dechering KJ.

Proc Natl Acad Sci U S A. 2018 Jul 17;115(29):E6920-E6926. doi: 10.1073/pnas.1801338115. Epub 2018 Jul 2.


Biased G Protein-Coupled Receptor Signaling: Changing the Paradigm of Drug Discovery.

Wisler JW, Rockman HA, Lefkowitz RJ.

Circulation. 2018 May 29;137(22):2315-2317. doi: 10.1161/CIRCULATIONAHA.117.028194. Review. No abstract available.


Management outcomes of diverticulitis and colitis in patients with active cancer.

Horwood C, Wisler J, Byrd S, Woodling K, Schneider EB, Rushing A.

Surgery. 2018 Aug;164(2):350-353. doi: 10.1016/j.surg.2018.03.010. Epub 2018 May 23.


Elevated histone H3 acetylation is associated with genes involved in T lymphocyte activation and glutamate decarboxylase antibody production in patients with type 1 diabetes.

Wang Y, Hou C, Wisler J, Singh K, Wu C, Xie Z, Lu Q, Zhou Z.

J Diabetes Investig. 2019 Jan;10(1):51-61. doi: 10.1111/jdi.12867. Epub 2018 Jun 26.


β-Arrestin2 mediates progression of murine primary myelofibrosis.

Rein LA, Wisler JW, Kim J, Theriot B, Huang L, Price T, Yang H, Chen M, Chen W, Sipkins D, Fedoriw Y, Walker JK, Premont RT, Lefkowitz RJ.

JCI Insight. 2017 Dec 21;2(24). pii: 98094. doi: 10.1172/jci.insight.98094.


Conformationally selective RNA aptamers allosterically modulate the β2-adrenoceptor.

Kahsai AW, Wisler JW, Lee J, Ahn S, Cahill Iii TJ, Dennison SM, Staus DP, Thomsen AR, Anasti KM, Pani B, Wingler LM, Desai H, Bompiani KM, Strachan RT, Qin X, Alam SM, Sullenger BA, Lefkowitz RJ.

Nat Chem Biol. 2016 Sep;12(9):709-16. doi: 10.1038/nchembio.2126. Epub 2016 Jul 11.


The role of β-arrestin2-dependent signaling in thoracic aortic aneurysm formation in a murine model of Marfan syndrome.

Wisler JW, Harris EM, Raisch M, Mao L, Kim J, Rockman HA, Lefkowitz RJ.

Am J Physiol Heart Circ Physiol. 2015 Nov;309(9):H1516-27. doi: 10.1152/ajpheart.00291.2015. Epub 2015 Sep 14.


Prediction of clinical pharmacokinetics of AMG 181, a human anti-α 4 β 7 monoclonal antibody for treating inflammatory bowel diseases.

Li H, Köck K, Wisler JA, Rees WA, Prince PJ, Reynhardt KO, Hsu H, Yu Z, Borie DC, Salinger DH, Pan WJ.

Pharmacol Res Perspect. 2015 Feb;3(1):e00098. doi: 10.1002/prp2.98. Epub 2014 Dec 9.


Author's reply: To PMID 25370543.

Wisler JR, Springer AN, Hateley K, Mo XM, Evans DC, Cook CH, Gerlach AT, Murphy CV, Eiferman DS, Steinberg SM, Bergese SD, Papadimos TJ, Stawicki SP.

J Postgrad Med. 2015 Jan-Mar;61(1):58-9. No abstract available.


Author's reply: To PMID 25370543.

Wisler JR, Springer AN, Hateley K, Mo XM, Evans DC, Cook CH, Gerlach AT, Murphy CV, Eiferman DS, Steinberg SM, Bergese SD, Papadimos TJ, Stawicki SP.

J Postgrad Med. 2015 Jan-Mar;61(1):57. No abstract available.


Pre-injury neuro-psychiatric medication use, alone or in combination with cardiac medications, may affect outcomes in trauma patients.

Wisler JR, Springer AN, Hateley K, Mo XM, Evans DC, Cook CH, Gerlach AT, Murphy CV, Eiferman DS, Steinberg SM, Bergese SD, Papadimos TJ, Stawicki SP.

J Postgrad Med. 2014 Oct-Dec;60(4):366-71. doi: 10.4103/0022-3859.143957.


Antithrombotic therapy: new areas to understand efficacy and bleeding.

Wisler JW, Becker RC.

Expert Opin Ther Targets. 2014 Dec;18(12):1427-34. doi: 10.1517/14728222.2014.953929. Epub 2014 Oct 27. Review.


Recent developments in biased agonism.

Wisler JW, Xiao K, Thomsen AR, Lefkowitz RJ.

Curr Opin Cell Biol. 2014 Apr;27:18-24. doi: 10.1016/ Epub 2013 Nov 20. Review.


Methodological challenges in utilizing miRNAs as circulating biomarkers.

Moldovan L, Batte KE, Trgovcich J, Wisler J, Marsh CB, Piper M.

J Cell Mol Med. 2014 Mar;18(3):371-90. doi: 10.1111/jcmm.12236. Epub 2014 Feb 18. Review.


Emerging paradigms in arterial thrombosis.

Wisler JW, Becker RC.

J Thromb Thrombolysis. 2014 Jan;37(1):4-11. doi: 10.1007/s11239-013-0965-1. Review.


Analyzing the circulating microRNAs in exosomes/extracellular vesicles from serum or plasma by qRT-PCR.

Moldovan L, Batte K, Wang Y, Wisler J, Piper M.

Methods Mol Biol. 2013;1024:129-45. doi: 10.1007/978-1-62703-453-1_10.


Pharmacology of AMG 181, a human anti-α4 β7 antibody that specifically alters trafficking of gut-homing T cells.

Pan WJ, Hsu H, Rees WA, Lear SP, Lee F, Foltz IN, Rathanaswami P, Manchulenko K, Chan BM, Zhang M, Xia XZ, Patel SK, Prince PJ, Doherty DR, Sheckler CM, Reynhardt KO, Krill CD, Harder BJ, Wisler JA, Brandvig JL, Lynch JL, Anderson AA, Wienkers LC, Borie DC.

Br J Pharmacol. 2013 May;169(1):51-68. doi: 10.1111/bph.12134.


The relationship between acute and chronic hyperglycemia and outcomes in burn injury.

Murphy CV, Coffey R, Wisler J, Miller SF.

J Burn Care Res. 2013 Jan-Feb;34(1):109-14. doi: 10.1097/BCR.0b013e3182700025.


MARCH2 promotes endocytosis and lysosomal sorting of carvedilol-bound β(2)-adrenergic receptors.

Han SO, Xiao K, Kim J, Wu JH, Wisler JW, Nakamura N, Freedman NJ, Shenoy SK.

J Cell Biol. 2012 Nov 26;199(5):817-30. doi: 10.1083/jcb.201208192. Epub 2012 Nov 19.


Macrophage microvesicles induce macrophage differentiation and miR-223 transfer.

Ismail N, Wang Y, Dakhlallah D, Moldovan L, Agarwal K, Batte K, Shah P, Wisler J, Eubank TD, Tridandapani S, Paulaitis ME, Piper MG, Marsh CB.

Blood. 2013 Feb 7;121(6):984-95. doi: 10.1182/blood-2011-08-374793. Epub 2012 Nov 9.


Challenges and opportunities in implementing pharmacogenomics testing in the clinics.

Wisler JR, Wisler JW, Bansal S, Marsh CB.

Per Med. 2012 Aug;9(6):609-619. doi: 10.2217/pme.12.64.


A guidance pathway for the selection of novel anticoagulants in the treatment of atrial fibrillation.

Wisler JW, Becker RC.

Crit Pathw Cardiol. 2012 Jun;11(2):55-61. doi: 10.1097/HPC.0b013e31825298ef. Review.


Oral factor Xa inhibitors for the long-term management of ACS.

Wisler JW, Becker RC.

Nat Rev Cardiol. 2012 Feb 21;9(7):392-401. doi: 10.1038/nrcardio.2012.18. Review.


Dynamic changes in respiratory frequency/tidal volume may predict failures of ventilatory liberation in patients on prolonged mechanical ventilation and normal preliberation respiratory frequency/tidal volume values.

Adams RC, Gunter OL, Wisler JR, Whitmill ML, Cipolla J, Lindsey DE, Stehly C, Steinberg SM, Cook CH, Stawicki SP.

Am Surg. 2012 Jan;78(1):69-73.


Evaluation of dose requirements for prolonged bivalirudin administration in patients with renal insufficiency and suspected heparin-induced thrombocytopenia.

Wisler JW, Washam JB, Becker RC.

J Thromb Thrombolysis. 2012 Apr;33(3):287-95. doi: 10.1007/s11239-011-0677-3.


Raf inhibition causes extensive multiple tissue hyperplasia and urinary bladder neoplasia in the rat.

Wisler JA, Afshari C, Fielden M, Zimmermann C, Taylor S, Carnahan J, Vonderfecht S.

Toxicol Pathol. 2011 Aug;39(5):809-22. doi: 10.1177/0192623311410442. Epub 2011 Jun 15.


Review of abdominal damage control and open abdomens: focus on gastrointestinal complications.

Smith BP, Adams RC, Doraiswamy VA, Nagaraja V, Seamon MJ, Wisler J, Cipolla J, Sharma R, Cook CH, Gunter OL, Stawicki SP.

J Gastrointestin Liver Dis. 2010 Dec;19(4):425-35. Review.


The diversity of wound presentation associated with freon contact frostbite injury.

Wisler JW, Wisler JR, Coffey R, Miller SF.

J Burn Care Res. 2010 Sep-Oct;31(5):809-12. doi: 10.1097/BCR.0b013e3181eed452.


beta-arrestin-biased agonism at the beta2-adrenergic receptor.

Drake MT, Violin JD, Whalen EJ, Wisler JW, Shenoy SK, Lefkowitz RJ.

J Biol Chem. 2008 Feb 29;283(9):5669-76. Epub 2007 Dec 17.


The effect of left ventricular size on right ventricular hemodynamics in pediatric survivors with hypoplastic left heart syndrome.

Wisler J, Khoury PR, Kimball TR.

J Am Soc Echocardiogr. 2008 May;21(5):464-9. Epub 2007 Oct 25.


A unique mechanism of beta-blocker action: carvedilol stimulates beta-arrestin signaling.

Wisler JW, DeWire SM, Whalen EJ, Violin JD, Drake MT, Ahn S, Shenoy SK, Lefkowitz RJ.

Proc Natl Acad Sci U S A. 2007 Oct 16;104(42):16657-62. Epub 2007 Oct 9.


Domain structure and DNA binding regions of beta protein from bacteriophage lambda.

Wu Z, Xing X, Bohl CE, Wisler JW, Dalton JT, Bell CE.

J Biol Chem. 2006 Sep 1;281(35):25205-14. Epub 2006 Jul 3.


Probing the DNA sequence specificity of Escherichia coli RECA protein.

Rajan R, Wisler JW, Bell CE.

Nucleic Acids Res. 2006 May 9;34(8):2463-71. Print 2006.


Transport of cyanide into guinea pig cardiac mitochondria.

Wisler JA, Dulaney MD, Pellicore LS, Lenz DE.

Toxicol Lett. 1991 May;56(3):275-81.


Supplemental Content

Loading ...
Support Center