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Items: 1 to 50 of 129

1.

Histamine: Neural circuits and new medications.

Scammell TE, Jackson AC, Franks NP, Wisden W, Dauvilliers Y.

Sleep. 2018 Sep 18. doi: 10.1093/sleep/zsy183. [Epub ahead of print]

PMID:
30239935
2.

A Neuronal Hub Binding Sleep Initiation and Body Cooling in Response to a Warm External Stimulus.

Harding EC, Yu X, Miao A, Andrews N, Ma Y, Ye Z, Lignos L, Miracca G, Ba W, Yustos R, Vyssotski AL, Wisden W, Franks NP.

Curr Biol. 2018 Jul 23;28(14):2263-2273.e4. doi: 10.1016/j.cub.2018.05.054. Epub 2018 Jul 12.

3.

Sleep and Sedative States Induced by Targeting the Histamine and Noradrenergic Systems.

Yu X, Franks NP, Wisden W.

Front Neural Circuits. 2018 Jan 26;12:4. doi: 10.3389/fncir.2018.00004. eCollection 2018. Review.

4.

Excitatory Pathways from the Lateral Habenula Enable Propofol-Induced Sedation.

Gelegen C, Miracca G, Ran MZ, Harding EC, Ye Z, Yu X, Tossell K, Houston CM, Yustos R, Hawkins ED, Vyssotski AL, Dong HL, Wisden W, Franks NP.

Curr Biol. 2018 Feb 19;28(4):580-587.e5. doi: 10.1016/j.cub.2017.12.050. Epub 2018 Feb 1.

5.

GABA Receptors and the Pharmacology of Sleep.

Wisden W, Yu X, Franks NP.

Handb Exp Pharmacol. 2017 Oct 10. doi: 10.1007/164_2017_56. [Epub ahead of print]

PMID:
28993837
6.

Dual-transmitter systems regulating arousal, attention, learning and memory.

Ma S, Hangya B, Leonard CS, Wisden W, Gundlach AL.

Neurosci Biobehav Rev. 2018 Feb;85:21-33. doi: 10.1016/j.neubiorev.2017.07.009. Epub 2017 Jul 27. Review.

PMID:
28757457
7.

Fast and Slow Inhibition in the Visual Thalamus Is Influenced by Allocating GABAA Receptors with Different γ Subunits.

Ye Z, Yu X, Houston CM, Aboukhalil Z, Franks NP, Wisden W, Brickley SG.

Front Cell Neurosci. 2017 Apr 4;11:95. doi: 10.3389/fncel.2017.00095. eCollection 2017.

8.

A Tribute to Peter H Seeburg (1944-2016): A Founding Father of Molecular Neurobiology.

Wisden W.

Front Mol Neurosci. 2016 Nov 29;9:133. eCollection 2016. No abstract available.

9.

Tectal-derived interneurons contribute to phasic and tonic inhibition in the visual thalamus.

Jager P, Ye Z, Yu X, Zagoraiou L, Prekop HT, Partanen J, Jessell TM, Wisden W, Brickley SG, Delogu A.

Nat Commun. 2016 Dec 8;7:13579. doi: 10.1038/ncomms13579.

10.

Increased Motor-Impairing Effects of the Neuroactive Steroid Pregnanolone in Mice with Targeted Inactivation of the GABAA Receptor γ2 Subunit in the Cerebellum.

Leppä E, Linden AM, Aller MI, Wulff P, Vekovischeva O, Luscher B, Lüddens H, Wisden W, Korpi ER.

Front Pharmacol. 2016 Oct 27;7:403. eCollection 2016.

11.

Bottom-Up versus Top-Down Induction of Sleep by Zolpidem Acting on Histaminergic and Neocortex Neurons.

Uygun DS, Ye Z, Zecharia AY, Harding EC, Yu X, Yustos R, Vyssotski AL, Brickley SG, Franks NP, Wisden W.

J Neurosci. 2016 Nov 2;36(44):11171-11184.

12.

Wakefulness Is Governed by GABA and Histamine Cotransmission.

Yu X, Ye Z, Houston CM, Zecharia AY, Ma Y, Zhang Z, Uygun DS, Parker S, Vyssotski AL, Yustos R, Franks NP, Brickley SG, Wisden W.

Neuron. 2015 Jul 1;87(1):164-78. doi: 10.1016/j.neuron.2015.06.003. Epub 2015 Jun 18.

13.

Neuronal ensembles sufficient for recovery sleep and the sedative actions of α2 adrenergic agonists.

Zhang Z, Ferretti V, Güntan İ, Moro A, Steinberg EA, Ye Z, Zecharia AY, Yu X, Vyssotski AL, Brickley SG, Yustos R, Pillidge ZE, Harding EC, Wisden W, Franks NP.

Nat Neurosci. 2015 Apr;18(4):553-561. doi: 10.1038/nn.3957. Epub 2015 Feb 23.

14.

The role of K₂p channels in anaesthesia and sleep.

Steinberg EA, Wafford KA, Brickley SG, Franks NP, Wisden W.

Pflugers Arch. 2015 May;467(5):907-16. doi: 10.1007/s00424-014-1654-4. Epub 2014 Dec 9. Review.

15.

Circadian factor BMAL1 in histaminergic neurons regulates sleep architecture.

Yu X, Zecharia A, Zhang Z, Yang Q, Yustos R, Jager P, Vyssotski AL, Maywood ES, Chesham JE, Ma Y, Brickley SG, Hastings MH, Franks NP, Wisden W.

Curr Biol. 2014 Dec 1;24(23):2838-44. doi: 10.1016/j.cub.2014.10.019. Epub 2014 Nov 13.

16.

Altered activity in the central medial thalamus precedes changes in the neocortex during transitions into both sleep and propofol anesthesia.

Baker R, Gent TC, Yang Q, Parker S, Vyssotski AL, Wisden W, Brickley SG, Franks NP.

J Neurosci. 2014 Oct 1;34(40):13326-35. doi: 10.1523/JNEUROSCI.1519-14.2014.

17.

Cytoplasmic domain of δ subunit is important for the extra-synaptic targeting of GABAA receptor subtypes.

Arslan A, von Engelhardt J, Wisden W.

J Integr Neurosci. 2014 Dec;13(4):617-31. doi: 10.1142/S0219635214500228.

PMID:
25233879
18.

Staying awake--a genetic region that hinders α2 adrenergic receptor agonist-induced sleep.

Gelegen C, Gent TC, Ferretti V, Zhang Z, Yustos R, Lan F, Yang Q, Overington DW, Vyssotski AL, van Lith HA, Wisden W, Franks NP.

Eur J Neurosci. 2014 Jul;40(1):2311-9. doi: 10.1111/ejn.12570. Epub 2014 Mar 27.

19.

Synaptic transmission and plasticity at inputs to murine cerebellar Purkinje cells are largely dispensable for standard nonmotor tasks.

Galliano E, Potters JW, Elgersma Y, Wisden W, Kushner SA, De Zeeuw CI, Hoebeek FE.

J Neurosci. 2013 Jul 31;33(31):12599-618. doi: 10.1523/JNEUROSCI.1642-13.2013.

20.

Synaptic competition sculpts the development of GABAergic axo-dendritic but not perisomatic synapses.

Frola E, Patrizi A, Goetz T, Medrihan L, Petrini EM, Barberis A, Wulff P, Wisden W, Sassoè-Pognetto M.

PLoS One. 2013;8(2):e56311. doi: 10.1371/journal.pone.0056311. Epub 2013 Feb 14.

21.

GABAergic inhibition of histaminergic neurons regulates active waking but not the sleep-wake switch or propofol-induced loss of consciousness.

Zecharia AY, Yu X, Götz T, Ye Z, Carr DR, Wulff P, Bettler B, Vyssotski AL, Brickley SG, Franks NP, Wisden W.

J Neurosci. 2012 Sep 19;32(38):13062-75.

22.

Raising cytosolic Cl- in cerebellar granule cells affects their excitability and vestibulo-ocular learning.

Seja P, Schonewille M, Spitzmaul G, Badura A, Klein I, Rudhard Y, Wisden W, Hübner CA, De Zeeuw CI, Jentsch TJ.

EMBO J. 2012 Mar 7;31(5):1217-30. doi: 10.1038/emboj.2011.488. Epub 2012 Jan 17.

23.

Removal of GABA(A) receptor γ2 subunits from parvalbumin neurons causes wide-ranging behavioral alterations.

Leppä E, Linden AM, Vekovischeva OY, Swinny JD, Rantanen V, Toppila E, Höger H, Sieghart W, Wulff P, Wisden W, Korpi ER.

PLoS One. 2011;6(9):e24159. doi: 10.1371/journal.pone.0024159. Epub 2011 Sep 2.

24.

Actions of two GABAA receptor benzodiazepine-site ligands that are mediated via non-γ2-dependent modulation.

Leppä E, Linden AM, Rabe H, Vekovischeva OY, Wulff P, Lüddens H, Wisden W, Korpi ER.

Eur J Pharmacol. 2011 Sep;666(1-3):111-21. doi: 10.1016/j.ejphar.2011.05.011. Epub 2011 May 19.

PMID:
21616065
25.

Parvalbumin-positive CA1 interneurons are required for spatial working but not for reference memory.

Murray AJ, Sauer JF, Riedel G, McClure C, Ansel L, Cheyne L, Bartos M, Wisden W, Wulff P.

Nat Neurosci. 2011 Mar;14(3):297-9. doi: 10.1038/nn.2751. Epub 2011 Jan 30.

26.

Ro 15-4513 Antagonizes Alcohol-Induced Sedation in Mice Through αβγ2-type GABA(A) Receptors.

Linden AM, Schmitt U, Leppä E, Wulff P, Wisden W, Lüddens H, Korpi ER.

Front Neurosci. 2011 Jan 20;5:3. doi: 10.3389/fnins.2011.00003. eCollection 2011.

27.

Cre-ating Ways to Serotonin.

Wisden W.

Front Neurosci. 2010 Dec 8;4:167. doi: 10.3389/fnins.2010.00167. eCollection 2010. No abstract available.

28.

Genetic techniques and circuit analysis.

Wisden W, Meier JC.

Front Mol Neurosci. 2010 Mar 3;3:4. doi: 10.3389/neuro.02.004.2010. eCollection 2010. No abstract available.

29.

Expression of the kcnk3 potassium channel gene lessens the injury from cerebral ischemia, most likely by a general influence on blood pressure.

Muhammad S, Aller MI, Maser-Gluth C, Schwaninger M, Wisden W.

Neuroscience. 2010 May 19;167(3):758-64. doi: 10.1016/j.neuroscience.2010.02.024. Epub 2010 Feb 16.

PMID:
20167264
30.

Studying Cerebellar Circuits by Remote Control of Selected Neuronal Types with GABA(A) Receptors.

Wisden W, Murray AJ, McClure C, Wulff P.

Front Mol Neurosci. 2009 Dec 11;2:29. doi: 10.3389/neuro.02.029.2009. eCollection 2009.

31.

An unexpected role for TASK-3 potassium channels in network oscillations with implications for sleep mechanisms and anesthetic action.

Pang DS, Robledo CJ, Carr DR, Gent TC, Vyssotski AL, Caley A, Zecharia AY, Wisden W, Brickley SG, Franks NP.

Proc Natl Acad Sci U S A. 2009 Oct 13;106(41):17546-51. doi: 10.1073/pnas.0907228106. Epub 2009 Sep 24.

32.

Synaptic inhibition of Purkinje cells mediates consolidation of vestibulo-cerebellar motor learning.

Wulff P, Schonewille M, Renzi M, Viltono L, Sassoè-Pognetto M, Badura A, Gao Z, Hoebeek FE, van Dorp S, Wisden W, Farrant M, De Zeeuw CI.

Nat Neurosci. 2009 Aug;12(8):1042-9. doi: 10.1038/nn.2348. Epub 2009 Jul 5.

33.

Neuregulin signaling is dispensable for NMDA- and GABA(A)-receptor expression in the cerebellum in vivo.

Gajendran N, Kapfhammer JP, Lain E, Canepari M, Vogt K, Wisden W, Brenner HR.

J Neurosci. 2009 Feb 25;29(8):2404-13. doi: 10.1523/JNEUROSCI.4303-08.2009.

34.

Hippocampal theta rhythm and its coupling with gamma oscillations require fast inhibition onto parvalbumin-positive interneurons.

Wulff P, Ponomarenko AA, Bartos M, Korotkova TM, Fuchs EC, Bähner F, Both M, Tort AB, Kopell NJ, Wisden W, Monyer H.

Proc Natl Acad Sci U S A. 2009 Mar 3;106(9):3561-6. doi: 10.1073/pnas.0813176106. Epub 2009 Feb 9.

35.

A role for TASK-1 (KCNK3) channels in the chemosensory control of breathing.

Trapp S, Aller MI, Wisden W, Gourine AV.

J Neurosci. 2008 Aug 27;28(35):8844-50. doi: 10.1523/JNEUROSCI.1810-08.2008.

36.

K+ channel TASK-1 knockout mice show enhanced sensitivities to ataxic and hypnotic effects of GABA(A) receptor ligands.

Linden AM, Aller MI, Leppä E, Rosenberg PH, Wisden W, Korpi ER.

J Pharmacol Exp Ther. 2008 Oct;327(1):277-86. doi: 10.1124/jpet.108.142083. Epub 2008 Jul 25.

37.

Changes in expression of some two-pore domain potassium channel genes (KCNK) in selected brain regions of developing mice.

Aller MI, Wisden W.

Neuroscience. 2008 Feb 19;151(4):1154-72. doi: 10.1016/j.neuroscience.2007.12.011. Epub 2007 Dec 23.

PMID:
18222039
38.

Invalidation of TASK1 potassium channels disrupts adrenal gland zonation and mineralocorticoid homeostasis.

Heitzmann D, Derand R, Jungbauer S, Bandulik S, Sterner C, Schweda F, El Wakil A, Lalli E, Guy N, Mengual R, Reichold M, Tegtmeier I, Bendahhou S, Gomez-Sanchez CE, Aller MI, Wisden W, Weber A, Lesage F, Warth R, Barhanin J.

EMBO J. 2008 Jan 9;27(1):179-87. Epub 2007 Nov 22.

39.

TASK-3 knockout mice exhibit exaggerated nocturnal activity, impairments in cognitive functions, and reduced sensitivity to inhalation anesthetics.

Linden AM, Sandu C, Aller MI, Vekovischeva OY, Rosenberg PH, Wisden W, Korpi ER.

J Pharmacol Exp Ther. 2007 Dec;323(3):924-34. Epub 2007 Sep 17.

40.

TASK-3 two-pore domain potassium channels enable sustained high-frequency firing in cerebellar granule neurons.

Brickley SG, Aller MI, Sandu C, Veale EL, Alder FG, Sambi H, Mathie A, Wisden W.

J Neurosci. 2007 Aug 29;27(35):9329-40.

41.

Does ethanol act preferentially via selected brain GABAA receptor subtypes? the current evidence is ambiguous.

Korpi ER, Debus F, Linden AM, Malécot C, Leppä E, Vekovischeva O, Rabe H, Böhme I, Aller MI, Wisden W, Lüddens H.

Alcohol. 2007 May;41(3):163-76. Review.

PMID:
17591542
42.

From synapse to behavior: rapid modulation of defined neuronal types with engineered GABAA receptors.

Wulff P, Goetz T, Leppä E, Linden AM, Renzi M, Swinny JD, Vekovischeva OY, Sieghart W, Somogyi P, Korpi ER, Farrant M, Wisden W.

Nat Neurosci. 2007 Jul;10(7):923-9. Epub 2007 Jun 17.

43.

GABA(A) receptors: structure and function in the basal ganglia.

Goetz T, Arslan A, Wisden W, Wulff P.

Prog Brain Res. 2007;160:21-41. Review.

44.

The contribution of TWIK-related acid-sensitive K+-containing channels to the function of dorsal lateral geniculate thalamocortical relay neurons.

Meuth SG, Aller MI, Munsch T, Schuhmacher T, Seidenbecher T, Meuth P, Kleinschnitz C, Pape HC, Wiendl H, Wisden W, Budde T.

Mol Pharmacol. 2006 Apr;69(4):1468-76. Epub 2006 Jan 19.

45.

The in vivo contributions of TASK-1-containing channels to the actions of inhalation anesthetics, the alpha(2) adrenergic sedative dexmedetomidine, and cannabinoid agonists.

Linden AM, Aller MI, Leppä E, Vekovischeva O, Aitta-Aho T, Veale EL, Mathie A, Rosenberg P, Wisden W, Korpi ER.

J Pharmacol Exp Ther. 2006 May;317(2):615-26. Epub 2006 Jan 5.

46.

Modifying the subunit composition of TASK channels alters the modulation of a leak conductance in cerebellar granule neurons.

Aller MI, Veale EL, Linden AM, Sandu C, Schwaninger M, Evans LJ, Korpi ER, Mathie A, Wisden W, Brickley SG.

J Neurosci. 2005 Dec 7;25(49):11455-67.

47.

Loss of zolpidem efficacy in the hippocampus of mice with the GABAA receptor gamma2 F77I point mutation.

Cope DW, Halbsguth C, Karayannis T, Wulff P, Ferraguti F, Hoeger H, Leppä E, Linden AM, Oberto A, Ogris W, Korpi ER, Sieghart W, Somogyi P, Wisden W, Capogna M.

Eur J Neurosci. 2005 Jun;21(11):3002-16.

PMID:
15978011
48.

Agonistic effects of the beta-carboline DMCM revealed in GABA(A) receptor gamma 2 subunit F77I point-mutated mice.

Leppä E, Vekovischeva OY, Lindén AM, Wulff P, Oberto A, Wisden W, Korpi ER.

Neuropharmacology. 2005 Mar;48(4):469-78. Epub 2005 Jan 25.

PMID:
15755475
49.

DNA repair in post-mitotic neurons: a gene-trapping strategy.

Merlo D, Di Stasi AM, Bonini P, Mollinari C, Cardinale A, Cozzolino F, Wisden W, Garaci E.

Cell Death Differ. 2005 Mar;12(3):307-9. No abstract available.

50.

Dissecting neural circuitry by combining genetics and pharmacology.

Wulff P, Wisden W.

Trends Neurosci. 2005 Jan;28(1):44-50. Review.

PMID:
15626496

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