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Items: 22


Mechanisms of PDZ domain scaffold assembly illuminated by use of supported cell membrane sheets.

Erlendsson S, Thorsen TS, Vauquelin G, Ammendrup-Johnsen I, Wirth V, Martinez KL, Teilum K, Gether U, Madsen KL.

Elife. 2019 Jan 3;8. pii: e39180. doi: 10.7554/eLife.39180.


Meropenem Combined with Ciprofloxacin Combats Hypermutable Pseudomonas aeruginosa from Respiratory Infections of Cystic Fibrosis Patients.

Rees VE, Yadav R, Rogers KE, Bulitta JB, Wirth V, Oliver A, Boyce JD, Peleg AY, Nation RL, Landersdorfer CB.

Antimicrob Agents Chemother. 2018 Oct 24;62(11). pii: e01150-18. doi: 10.1128/AAC.01150-18. Print 2018 Nov.


Polymyxin B in Combination with Enrofloxacin Exerts Synergistic Killing against Extensively Drug-Resistant Pseudomonas aeruginosa.

Lin YW, Yu HH, Zhao J, Han ML, Zhu Y, Akter J, Wickremasinghe H, Walpola H, Wirth V, Rao GG, Forrest A, Velkov T, Li J.

Antimicrob Agents Chemother. 2018 May 25;62(6). pii: e00028-18. doi: 10.1128/AAC.00028-18. Print 2018 Jun.


Pharmacokinetics/pharmacodynamics of systemically administered polymyxin B against Klebsiella pneumoniae in mouse thigh and lung infection models.

Landersdorfer CB, Wang J, Wirth V, Chen K, Kaye KS, Tsuji BT, Li J, Nation RL.

J Antimicrob Chemother. 2018 Feb 1;73(2):462-468. doi: 10.1093/jac/dkx409.


Aerosolized Polymyxin B for Treatment of Respiratory Tract Infections: Determination of Pharmacokinetic-Pharmacodynamic Indices for Aerosolized Polymyxin B against Pseudomonas aeruginosa in a Mouse Lung Infection Model.

Lin YW, Zhou Q, Onufrak NJ, Wirth V, Chen K, Wang J, Forrest A, Chan HK, Li J.

Antimicrob Agents Chemother. 2017 Jul 25;61(8). pii: e00211-17. doi: 10.1128/AAC.00211-17. Print 2017 Aug.


Membrane curvature regulates ligand-specific membrane sorting of GPCRs in living cells.

Rosholm KR, Leijnse N, Mantsiou A, Tkach V, Pedersen SL, Wirth VF, Oddershede LB, Jensen KJ, Martinez KL, Hatzakis NS, Bendix PM, Callan-Jones A, Stamou D.

Nat Chem Biol. 2017 Jul;13(7):724-729. doi: 10.1038/nchembio.2372. Epub 2017 May 8.


Prodrugs of imidazotriazine and pyrrolotriazine C-nucleosides can increase anti-HCV activity and enhance nucleotide triphosphate concentrations in vitro.

Tyndall EM, Draffan AG, Frey B, Pool B, Halim R, Jahangiri S, Bond S, Wirth V, Luttick A, Tilmanis D, Thomas J, Porter K, Tucker SP.

Bioorg Med Chem Lett. 2015 Feb 15;25(4):869-73. doi: 10.1016/j.bmcl.2014.12.069. Epub 2014 Dec 30.


Derivatives of imidazotriazine and pyrrolotriazine C-nucleosides as potential new anti-HCV agents.

Draffan AG, Frey B, Fraser BH, Pool B, Gannon C, Tyndall EM, Cianci J, Harding M, Lilly M, Hufton R, Halim R, Jahangiri S, Bond S, Jeynes TP, Nguyen VT, Wirth V, Luttick A, Tilmanis D, Pryor M, Porter K, Morton CJ, Lin B, Duan J, Bethell RC, Kukolj G, Simoneau B, Tucker SP.

Bioorg Med Chem Lett. 2014 Nov 1;24(21):4984-8. doi: 10.1016/j.bmcl.2014.09.030. Epub 2014 Sep 21.


Discovery and Synthesis of C-Nucleosides as Potential New Anti-HCV Agents.

Draffan AG, Frey B, Pool B, Gannon C, Tyndall EM, Lilly M, Francom P, Hufton R, Halim R, Jahangiri S, Bond S, Nguyen VT, Jeynes TP, Wirth V, Luttick A, Tilmanis D, Thomas JD, Pryor M, Porter K, Morton CJ, Lin B, Duan J, Kukolj G, Simoneau B, McKercher G, Lagacé L, Amad M, Bethell RC, Tucker SP.

ACS Med Chem Lett. 2014 Apr 10;5(6):679-84. doi: 10.1021/ml500077j. eCollection 2014 Jun 12.


PDZ domain-mediated interactions of G protein-coupled receptors with postsynaptic density protein 95: quantitative characterization of interactions.

Møller TC, Wirth VF, Roberts NI, Bender J, Bach A, Jacky BP, Strømgaard K, Deussing JM, Schwartz TW, Martinez KL.

PLoS One. 2013 May 14;8(5):e63352. doi: 10.1371/journal.pone.0063352. Print 2013.


Vinculin's C-terminal region facilitates phospholipid membrane insertion.

Wirth VF, List F, Diez G, Goldmann WH.

Biochem Biophys Res Commun. 2010 Jul 30;398(3):433-7. doi: 10.1016/j.bbrc.2010.06.094. Epub 2010 Jul 1.


Temperature changes in deep muscles of humans during upper and lower extremity exercise.

Wirth VJ, Van Lunen BL, Mistry D, Saliba E, McCue FC.

J Athl Train. 1998 Jul;33(3):211-5.


Phase I trial of 131I-huA33 in patients with advanced colorectal carcinoma.

Chong G, Lee FT, Hopkins W, Tebbutt N, Cebon JS, Mountain AJ, Chappell B, Papenfuss A, Schleyer P, U P, Murphy R, Wirth V, Smyth FE, Potasz N, Poon A, Davis ID, Saunder T, O'keefe GJ, Burgess AW, Hoffman EW, Old LJ, Scott AM.

Clin Cancer Res. 2005 Jul 1;11(13):4818-26.


A phase I trial of humanized monoclonal antibody A33 in patients with colorectal carcinoma: biodistribution, pharmacokinetics, and quantitative tumor uptake.

Scott AM, Lee FT, Jones R, Hopkins W, MacGregor D, Cebon JS, Hannah A, Chong G, U P, Papenfuss A, Rigopoulos A, Sturrock S, Murphy R, Wirth V, Murone C, Smyth FE, Knight S, Welt S, Ritter G, Richards E, Nice EC, Burgess AW, Old LJ.

Clin Cancer Res. 2005 Jul 1;11(13):4810-7.


Generation of anti-idiotype antibodies for application in clinical immunotherapy laboratory analyses.

Liu Z, Panousis C, Smyth FE, Murphy R, Wirth V, Cartwright G, Johns TG, Scott AM.

Hybrid Hybridomics. 2003 Aug;22(4):219-28.


Detection of hidden regimes in stochastic cyclostationary time series.

Wirth V.

Phys Rev E Stat Nonlin Soft Matter Phys. 2001 Jul;64(1 Pt 2):016136. Epub 2001 Jun 28.


Epilithic Lichen-Atmospheric Deposition Monitors of Trace Elements and Organohalogens?

Matschullat J, Scharnweber T, Garbe-Schönberg D, Walther A, Wirth V.

J Air Waste Manag Assoc. 1999 Oct;49(10):1201-1211. doi: 10.1080/10473289.1999.10463921.


A case of contact dermatitis from lichens in southern Germany.

Hahn M, Lischka G, Pfeifle J, Wirth V.

Contact Dermatitis. 1995 Jan;32(1):55-6. No abstract available.


Effective energy resolution and scatter rejection in nuclear medicine.

Wirth V.

Phys Med Biol. 1989 Jan;34(1):85-90.


The pH dependence of SO2 damage to lichens.

Türk R, Wirth V.

Oecologia. 1975 Dec;19(4):285-291. doi: 10.1007/BF00348104.


CO2-Gaswechsel-Untersuchungen zur SO2-Resistenz von Flechten.

Rürk R, Wirth V, Lange OL.

Oecologia. 1974 Mar;15(1):33-64. doi: 10.1007/BF00345227. German.


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