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Items: 1 to 50 of 117

1.

Structural States of Hdm2 and HdmX: X-ray Elucidation of Adaptations and Binding Interactions for Different Chemical Compound Classes.

Kallen J, Izaac A, Chau S, Wirth E, Schoepfer J, Mah R, Schlapbach A, Stutz S, Vaupel A, Guagnano V, Masuya K, Stachyra TM, Salem B, Chene P, Gessier F, Holzer P, Furet P.

ChemMedChem. 2019 Jul 17;14(14):1305-1314. doi: 10.1002/cmdc.201900201. Epub 2019 May 27.

PMID:
31066983
2.

Preliminary Study of Ultrasonic Welding as a Joining Process for Electrospun Nanofiber Mats.

Wirth E, Sabantina L, Weber MO, Finsterbusch K, Ehrmann A.

Nanomaterials (Basel). 2018 Sep 20;8(10). pii: E746. doi: 10.3390/nano8100746.

3.

A Novel Rubric to Evaluate Wearable Cameras for Assessment of Interrater Reliability.

Jozkowski AC, Presgraves EA, Hodges KL, Wirth EN, Brandstetter NE, Thayer MT.

OTJR (Thorofare N J). 2018 Apr;38(2):121-130. doi: 10.1177/1539449217753349. Epub 2018 Jan 17. Review.

PMID:
29338570
4.

Considerations and recommendations for selection and utilization of upper extremity clinical outcome assessments in human spinal cord injury trials.

Jones LAT, Bryden A, Wheeler TL, Tansey KE, Anderson KD, Beattie MS, Blight A, Curt A, Field-Fote E, Guest JD, Hseih J, Jakeman LB, Kalsi-Ryan S, Krisa L, Lammertse DP, Leiby B, Marino R, Schwab JM, Scivoletto G, Tulsky DS, Wirth E, Zariffa J, Kleitman N, Mulcahey MJ, Steeves JD.

Spinal Cord. 2018 May;56(5):414-425. doi: 10.1038/s41393-017-0015-5. Epub 2017 Dec 28. Review.

5.

Human Embryonic Stem Cell-Derived Oligodendrocyte Progenitor Cells: Preclinical Efficacy and Safety in Cervical Spinal Cord Injury.

Manley NC, Priest CA, Denham J, Wirth ED 3rd, Lebkowski JS.

Stem Cells Transl Med. 2017 Oct;6(10):1917-1929. doi: 10.1002/sctm.17-0065. Epub 2017 Aug 22.

6.

The human IL-17A/F heterodimer: a two-faced cytokine with unique receptor recognition properties.

Goepfert A, Lehmann S, Wirth E, Rondeau JM.

Sci Rep. 2017 Aug 21;7(1):8906. doi: 10.1038/s41598-017-08360-9.

7.

Policy Research Challenges in Comparing Care Models for Dual-Eligible Beneficiaries.

Van Cleave JH, Egleston BL, Brosch S, Wirth E, Lawson M, Sullivan-Marx EM, Naylor MD.

Policy Polit Nurs Pract. 2017 May;18(2):72-83. doi: 10.1177/1527154417721909. Epub 2017 Jul 24.

PMID:
28735567
8.

Comparative Toxicity of Two Chemical Dispersants and Dispersed Oil in Estuarine Organisms.

DeLorenzo ME, Key PB, Chung KW, Pisarski E, Shaddrix B, Wirth EF, Pennington PL, Wade J, Franco M, Fulton MH.

Arch Environ Contam Toxicol. 2018 Apr;74(3):414-430. doi: 10.1007/s00244-017-0430-9. Epub 2017 Jul 7.

PMID:
28687868
9.

Immune responses and long-term disease recurrence status after telomerase-based dendritic cell immunotherapy in patients with acute myeloid leukemia.

Khoury HJ, Collins RH Jr, Blum W, Stiff PS, Elias L, Lebkowski JS, Reddy A, Nishimoto KP, Sen D, Wirth ED 3rd, Case CC, DiPersio JF.

Cancer. 2017 Aug 15;123(16):3061-3072. doi: 10.1002/cncr.30696. Epub 2017 Apr 14.

10.

Effects of age and soybean isoflavones on hepatic cholesterol metabolism and thyroid hormone availability in acyclic female rats.

Šošić-Jurjević B, Lütjohann D, Jarić I, Miler M, Vojnović Milutinović D, Filipović B, Ajdžanović V, Renko K, Wirth EK, Janković S, Kӧhrle J, Milošević V.

Exp Gerontol. 2017 Jun;92:74-81. doi: 10.1016/j.exger.2017.03.016. Epub 2017 Mar 21.

PMID:
28336316
11.

Interdependence of thyroglobulin processing and thyroid hormone export in the mouse thyroid gland.

Weber J, McInnes J, Kizilirmak C, Rehders M, Qatato M, Wirth EK, Schweizer U, Verrey F, Heuer H, Brix K.

Eur J Cell Biol. 2017 Aug;96(5):440-456. doi: 10.1016/j.ejcb.2017.02.002. Epub 2017 Mar 6.

12.

Neuronal effects of thyroid hormone metabolites.

Wirth EK, Meyer F.

Mol Cell Endocrinol. 2017 Dec 15;458:136-142. doi: 10.1016/j.mce.2017.01.007. Epub 2017 Jan 11. Review.

PMID:
28088465
13.

Improved cancer immunotherapy by a CD25-mimobody conferring selectivity to human interleukin-2.

Arenas-Ramirez N, Zou C, Popp S, Zingg D, Brannetti B, Wirth E, Calzascia T, Kovarik J, Sommer L, Zenke G, Woytschak J, Regnier CH, Katopodis A, Boyman O.

Sci Transl Med. 2016 Nov 30;8(367):367ra166.

PMID:
27903862
14.

High Variability of Insulin Sensitivity in Closely Related Obese Mouse Inbred Strains.

Heise S, Trost J, Arends D, Wirth EK, Schäfer N, Köhrle J, Schürmann A, Brockmann GA.

Exp Clin Endocrinol Diabetes. 2016 Oct;124(9):519-528. Epub 2016 Jul 20.

PMID:
27437914
15.

Silychristin, a Flavonolignan Derived From the Milk Thistle, Is a Potent Inhibitor of the Thyroid Hormone Transporter MCT8.

Johannes J, Jayarama-Naidu R, Meyer F, Wirth EK, Schweizer U, Schomburg L, Köhrle J, Renko K.

Endocrinology. 2016 Apr;157(4):1694-701. doi: 10.1210/en.2015-1933. Epub 2016 Feb 24.

PMID:
26910310
16.

High T3, Low T4 Serum Levels in Mct8 Deficiency Are Not Caused by Increased Hepatic Conversion through Type I Deiodinase.

Wirth EK, Rijntjes E, Meyer F, Köhrle J, Schweizer U.

Eur Thyroid J. 2015 Sep;4(Suppl 1):87-91. doi: 10.1159/000381021. Epub 2015 May 23.

17.

Involvement of the L-Type Amino Acid Transporter Lat2 in the Transport of 3,3'-Diiodothyronine across the Plasma Membrane.

Kinne A, Wittner M, Wirth EK, Hinz KM, Schülein R, Köhrle J, Krause G.

Eur Thyroid J. 2015 Sep;4(Suppl 1):42-50. doi: 10.1159/000381542. Epub 2015 May 28.

18.

Baseline monitoring of organic sunscreen compounds along South Carolina's coastal marine environment.

Bratkovics S, Wirth E, Sapozhnikova Y, Pennington P, Sanger D.

Mar Pollut Bull. 2015 Dec 15;101(1):370-377. doi: 10.1016/j.marpolbul.2015.10.015. Epub 2015 Nov 2.

PMID:
26541983
19.

Thyroid hormone status affects expression of daily torpor and gene transcription in Djungarian hamsters (Phodopus sungorus).

Bank JH, Kemmling J, Rijntjes E, Wirth EK, Herwig A.

Horm Behav. 2015 Sep;75:120-9. doi: 10.1016/j.yhbeh.2015.09.006. Epub 2015 Oct 3.

PMID:
26435475
20.

A survey of trace element distribution in tissues of the dwarf sperm whale (Kogia sima) stranded along the South Carolina coast from 1990-2011.

Reed LA, McFee WE, Pennington PL, Wirth EF, Fulton MH.

Mar Pollut Bull. 2015 Nov 15;100(1):501-506. doi: 10.1016/j.marpolbul.2015.09.005. Epub 2015 Sep 16.

PMID:
26386505
21.

Development of Species-Specific Ah Receptor-Responsive Third Generation CALUX Cell Lines with Enhanced Responsiveness and Improved Detection Limits.

Brennan JC, He G, Tsutsumi T, Zhao J, Wirth E, Fulton MH, Denison MS.

Environ Sci Technol. 2015 Oct 6;49(19):11903-12. doi: 10.1021/acs.est.5b02906. Epub 2015 Sep 24.

22.

Preclinical safety of human embryonic stem cell-derived oligodendrocyte progenitors supporting clinical trials in spinal cord injury.

Priest CA, Manley NC, Denham J, Wirth ED 3rd, Lebkowski JS.

Regen Med. 2015 Nov;10(8):939-58. doi: 10.2217/rme.15.57. Epub 2015 Sep 8.

23.

Visceral Adipose Tissue in Patients with Crohn's Disease Correlates with Disease Activity, Inflammatory Markers, and Outcome.

Büning C, von Kraft C, Hermsdorf M, Gentz E, Wirth EK, Valentini L, Haas V.

Inflamm Bowel Dis. 2015 Nov;21(11):2590-7. doi: 10.1097/MIB.0000000000000527.

PMID:
26222339
24.

A Nonradioactive Uptake Assay for Rapid Analysis of Thyroid Hormone Transporter Function.

Jayarama-Naidu R, Johannes J, Meyer F, Wirth EK, Schomburg L, Köhrle J, Renko K.

Endocrinology. 2015 Jul;156(7):2739-45. doi: 10.1210/en.2015-1016. Epub 2015 Apr 24.

PMID:
25910050
25.

The relationship between land use and emerging and legacy contaminants in an Apex predator, the bottlenose dolphin (Tursiops truncatus), from two adjacent estuarine watersheds.

Adams J, Speakman T, Zolman E, Mitchum G, Wirth E, Bossart GD, Fair PA.

Environ Res. 2014 Nov;135:346-53. doi: 10.1016/j.envres.2014.08.037. Epub 2014 Oct 29.

PMID:
25462684
26.

An integrated assessment of habitat quality of national estuarine research reserves in the southeastern United States.

Balthis WL, Cooksey C, Fulton MF, Hyland JL, Riekerk GH, Van Dolah RF, Wirth EF.

Integr Environ Assess Manag. 2015 Apr;11(2):266-75. doi: 10.1002/ieam.1601. Epub 2014 Dec 12.

PMID:
25377068
27.

Nutritional strategy to prevent fatty liver and insulin resistance independent of obesity by reducing glucose-dependent insulinotropic polypeptide responses in mice.

Keyhani-Nejad F, Irmler M, Isken F, Wirth EK, Beckers J, Birkenfeld AL, Pfeiffer AF.

Diabetologia. 2015 Feb;58(2):374-83. doi: 10.1007/s00125-014-3423-5. Epub 2014 Oct 28.

PMID:
25348610
28.

Distribution and sources of PCBs (Aroclor 1268) in the Sapelo Island National estuarine research reserve.

Wirth EF, Pennington PL, Cooksey C, Schwacke L, Balthis L, Hyland J, Fulton MH.

Environ Monit Assess. 2014 Dec;186(12):8717-26. doi: 10.1007/s10661-014-4039-4. Epub 2014 Sep 11.

PMID:
25208520
29.

Transport of thyroid hormone in brain.

Wirth EK, Schweizer U, Köhrle J.

Front Endocrinol (Lausanne). 2014 Jun 24;5:98. doi: 10.3389/fendo.2014.00098. eCollection 2014. Review.

30.

Using procedural blanks to generate analyte-specific limits of detection for persistent organic pollutants based on GC-MS analysis.

Ragland JM, Liebert D, Wirth E.

Anal Chem. 2014 Aug 5;86(15):7696-704. doi: 10.1021/ac501615n. Epub 2014 Jul 16.

PMID:
25007285
31.

Impaired selenoprotein expression in brain triggers striatal neuronal loss leading to co-ordination defects in mice.

Seeher S, Carlson BA, Miniard AC, Wirth EK, Mahdi Y, Hatfield DL, Driscoll DM, Schweizer U.

Biochem J. 2014 Aug 15;462(1):67-75. doi: 10.1042/BJ20140423.

32.

Soy isoflavones interfere with thyroid hormone homeostasis in orchidectomized middle-aged rats.

Šošić-Jurjević B, Filipović B, Wirth EK, Živanović J, Radulović N, Janković S, Milošević V, Köhrle J.

Toxicol Appl Pharmacol. 2014 Jul 15;278(2):124-34. doi: 10.1016/j.taap.2014.04.018. Epub 2014 Apr 29.

PMID:
24793811
33.

Cerebellar hypoplasia in mice lacking selenoprotein biosynthesis in neurons.

Wirth EK, Bharathi BS, Hatfield D, Conrad M, Brielmeier M, Schweizer U.

Biol Trace Elem Res. 2014 May;158(2):203-10. doi: 10.1007/s12011-014-9920-z. Epub 2014 Mar 6.

34.

Organic and metal contamination in marine surface sediments of Guánica Bay, Puerto Rico.

Whitall D, Mason A, Pait A, Brune L, Fulton M, Wirth E, Vandiver L.

Mar Pollut Bull. 2014 Mar 15;80(1-2):293-301. doi: 10.1016/j.marpolbul.2013.12.053. Epub 2014 Jan 18.

PMID:
24447634
35.

Secisbp2 is essential for embryonic development and enhances selenoprotein expression.

Seeher S, Atassi T, Mahdi Y, Carlson BA, Braun D, Wirth EK, Klein MO, Reix N, Miniard AC, Schomburg L, Hatfield DL, Driscoll DM, Schweizer U.

Antioxid Redox Signal. 2014 Aug 20;21(6):835-49. doi: 10.1089/ars.2013.5358. Epub 2014 Feb 4.

36.

UPEC biomimickry at the urothelial barrier: lectin-functionalized PLGA microparticles for improved intravesical chemotherapy.

Neutsch L, Wambacher M, Wirth EM, Spijker S, Kählig H, Wirth M, Gabor F.

Int J Pharm. 2013 Jun 25;450(1-2):163-76. doi: 10.1016/j.ijpharm.2013.04.058. Epub 2013 Apr 26.

PMID:
23628404
37.

Synergistic targeting/prodrug strategies for intravesical drug delivery--lectin-modified PLGA microparticles enhance cytotoxicity of stearoyl gemcitabine by contact-dependent transfer.

Neutsch L, Wirth EM, Spijker S, Pichl C, Kählig H, Gabor F, Wirth M.

J Control Release. 2013 Jul 10;169(1-2):62-72. doi: 10.1016/j.jconrel.2013.04.004. Epub 2013 Apr 12.

PMID:
23588390
38.

Antifouling biocides in water and sediments from California marinas.

Sapozhnikova Y, Wirth E, Schiff K, Fulton M.

Mar Pollut Bull. 2013 Apr 15;69(1-2):189-94. doi: 10.1016/j.marpolbul.2013.01.039. Epub 2013 Feb 28.

PMID:
23453818
39.

Potential consequences of the Fukushima accident for off-site nuclear emergency management: a case study for Germany.

Gering F, Gerich B, Wirth E, Kirchner G.

Radiat Prot Dosimetry. 2013 Jul;155(2):146-54. doi: 10.1093/rpd/ncs323. Epub 2013 Jan 3.

PMID:
23287436
40.

Pharmaceuticals and personal care products (PPCPs) in treated wastewater discharges into Charleston Harbor, South Carolina.

Hedgespeth ML, Sapozhnikova Y, Pennington P, Clum A, Fairey A, Wirth E.

Sci Total Environ. 2012 Oct 15;437:1-9. doi: 10.1016/j.scitotenv.2012.07.076. Epub 2012 Aug 17.

PMID:
22902998
41.

Thyroid function is maintained despite increased oxidative stress in mice lacking selenoprotein biosynthesis in thyroid epithelial cells.

Chiu-Ugalde J, Wirth EK, Klein MO, Sapin R, Fradejas-Villar N, Renko K, Schomburg L, Köhrle J, Schweizer U.

Antioxid Redox Signal. 2012 Sep 15;17(6):902-13. doi: 10.1089/ars.2011.4055. Epub 2012 Apr 18.

PMID:
22369680
42.

Inhibition of xanthine oxidase reduces wasting and improves outcome in a rat model of cancer cachexia.

Springer J, Tschirner A, Hartman K, Palus S, Wirth EK, Ruis SB, Möller N, von Haehling S, Argiles JM, Köhrle J, Adams V, Anker SD, Doehner W.

Int J Cancer. 2012 Nov 1;131(9):2187-96. doi: 10.1002/ijc.27494. Epub 2012 Jul 9.

43.

The HPA axis modulates the CNS melanocortin control of liver triacylglyceride metabolism.

Wiedmer P, Chaudhary N, Rath M, Yi CX, Ananthakrishnan G, Nogueiras R, Wirth EK, Kirchner H, Schweizer U, Jonas W, Veyrat-Durebex C, Rohner-Jeanrenaud F, Schürmann A, Joost HG, Tschöp MH, Perez-Tilve D.

Physiol Behav. 2012 Feb 1;105(3):791-9. doi: 10.1016/j.physbeh.2011.10.019. Epub 2011 Oct 28.

44.

Fluoxetine effects on sheepshead minnow (Cyprinodon variegatus) locomotor activity.

Winder VL, Pennington PL, Hurd MW, Wirth EF.

J Environ Sci Health B. 2012;47(1):51-8. doi: 10.1080/03601234.2012.607767.

PMID:
22022788
45.

Monocarboxylate transporter 8 deficiency: altered thyroid morphology and persistent high triiodothyronine/thyroxine ratio after thyroidectomy.

Wirth EK, Sheu SY, Chiu-Ugalde J, Sapin R, Klein MO, Mossbrugger I, Quintanilla-Martinez L, de Angelis MH, Krude H, Riebel T, Rothe K, Köhrle J, Schmid KW, Schweizer U, Grüters A.

Eur J Endocrinol. 2011 Oct;165(4):555-61. doi: 10.1530/EJE-11-0369. Epub 2011 Aug 3.

PMID:
21813593
46.

Aminoaciduria, but normal thyroid hormone levels and signalling, in mice lacking the amino acid and thyroid hormone transporter Slc7a8.

Braun D, Wirth EK, Wohlgemuth F, Reix N, Klein MO, Grüters A, Köhrle J, Schweizer U.

Biochem J. 2011 Oct 15;439(2):249-55. doi: 10.1042/BJ20110759.

PMID:
21726201
47.

Response to Frederic Bretzner et al. "Target populations for first-in-human embryonic stem cell research in spinal cord injury".

Wirth E 3rd, Lebkowski JS, Lebacqz K.

Cell Stem Cell. 2011 May 6;8(5):476-8. doi: 10.1016/j.stem.2011.04.008.

48.

A two-step concept to derive a consistent set of intervention levels for radiation emergency planning and to translate international recommendations into practical guidance.

Wirth E, Baciu AC, Gerich B, Blaettler M, Buettner U, Calvarro JM, Hofer P, Holo EN, Kuhlen J, Molnar K, Nizamska M, Sogalla M, Turai I, Vandecasteele C.

Health Phys. 2011 May;100(5):482-90. doi: 10.1097/HP.0b013e3181f3f1d6.

PMID:
21451317
49.

The transcriptomic responses of the eastern oyster, Crassostrea virginica, to environmental conditions.

Chapman RW, Mancia A, Beal M, Veloso A, Rathburn C, Blair A, Holland AF, Warr GW, Didinato G, Sokolova IM, Wirth EF, Duffy E, Sanger D.

Mol Ecol. 2011 Apr;20(7):1431-49. doi: 10.1111/j.1365-294X.2011.05018.x. Epub 2011 Feb 24.

PMID:
21426432
50.

Developmental and cell type-specific expression of thyroid hormone transporters in the mouse brain and in primary brain cells.

Braun D, Kinne A, Bräuer AU, Sapin R, Klein MO, Köhrle J, Wirth EK, Schweizer U.

Glia. 2011 Mar;59(3):463-71. doi: 10.1002/glia.21116. Epub 2010 Dec 29.

PMID:
21264952

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