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Items: 1 to 50 of 169

1.

Complete Genome Sequence of Cupriavidus necator H16 (DSM 428).

Little GT, Ehsaan M, Arenas-López C, Jawed K, Winzer K, Kovacs K, Minton NP.

Microbiol Resour Announc. 2019 Sep 12;8(37). pii: e00814-19. doi: 10.1128/MRA.00814-19.

2.

The carbonic anhydrase of Clostridium autoethanogenum represents a new subclass of β-carbonic anhydrases.

Pander B, Harris G, Scott DJ, Winzer K, Köpke M, Simpson SD, Minton NP, Henstra AM.

Appl Microbiol Biotechnol. 2019 Sep;103(17):7275-7286. doi: 10.1007/s00253-019-10015-w. Epub 2019 Jul 25.

3.

A novel conjugal donor strain for improved DNA transfer into Clostridium spp.

Woods C, Humphreys CM, Rodrigues RM, Ingle P, Rowe P, Henstra AM, Köpke M, Simpson SD, Winzer K, Minton NP.

Anaerobe. 2019 Oct;59:184-191. doi: 10.1016/j.anaerobe.2019.06.020. Epub 2019 Jun 30.

4.

The genetic basis of 3-hydroxypropanoate metabolism in Cupriavidus necator H16.

Arenas-López C, Locker J, Orol D, Walter F, Busche T, Kalinowski J, Minton NP, Kovács K, Winzer K.

Biotechnol Biofuels. 2019 Jun 17;12:150. doi: 10.1186/s13068-019-1489-5. eCollection 2019.

5.

Engineering of vitamin prototrophy in Clostridium ljungdahlii and Clostridium autoethanogenum.

Annan FJ, Al-Sinawi B, Humphreys CM, Norman R, Winzer K, Köpke M, Simpson SD, Minton NP, Henstra AM.

Appl Microbiol Biotechnol. 2019 Jun;103(11):4633-4648. doi: 10.1007/s00253-019-09763-6. Epub 2019 Apr 10.

6.

Gsmodutils: a python based framework for test-driven genome scale metabolic model development.

Gilbert J, Pearcy N, Norman R, Millat T, Winzer K, King J, Hodgman C, Minton N, Twycross J.

Bioinformatics. 2019 Sep 15;35(18):3397-3403. doi: 10.1093/bioinformatics/btz088.

7.

Functional Genetic Elements for Controlling Gene Expression in Cupriavidus necator H16.

Alagesan S, Hanko EKR, Malys N, Ehsaan M, Winzer K, Minton NP.

Appl Environ Microbiol. 2018 Sep 17;84(19). pii: e00878-18. doi: 10.1128/AEM.00878-18. Print 2018 Oct 1.

8.

Progress towards platform chemical production using Clostridium autoethanogenum.

Norman ROJ, Millat T, Winzer K, Minton NP, Hodgman C.

Biochem Soc Trans. 2018 Jun 19;46(3):523-535. doi: 10.1042/BST20170259. Epub 2018 Apr 17. Review.

PMID:
29666216
9.

The Butanol Producing Microbe Clostridium beijerinckii NCIMB 14988 Manipulated Using Forward and Reverse Genetic Tools.

Little GT, Willson BJ, Heap JT, Winzer K, Minton NP.

Biotechnol J. 2018 Nov;13(11):e1700711. doi: 10.1002/biot.201700711. Epub 2018 Apr 29.

PMID:
29660854
10.

Quantitative Isotope-Dilution High-Resolution-Mass-Spectrometry Analysis of Multiple Intracellular Metabolites in Clostridium autoethanogenum with Uniformly 13C-Labeled Standards Derived from Spirulina.

Schatschneider S, Abdelrazig S, Safo L, Henstra AM, Millat T, Kim DH, Winzer K, Minton NP, Barrett DA.

Anal Chem. 2018 Apr 3;90(7):4470-4477. doi: 10.1021/acs.analchem.7b04758. Epub 2018 Mar 21.

11.

Polymers for binding of the gram-positive oral pathogen Streptococcus mutans.

Magennis EP, Francini N, Mastrotto F, Catania R, Redhead M, Fernandez-Trillo F, Bradshaw D, Churchley D, Winzer K, Alexander C, Mantovani G.

PLoS One. 2017 Jul 3;12(7):e0180087. doi: 10.1371/journal.pone.0180087. eCollection 2017.

12.

Microbial solvent formation revisited by comparative genome analysis.

Poehlein A, Solano JDM, Flitsch SK, Krabben P, Winzer K, Reid SJ, Jones DT, Green E, Minton NP, Daniel R, Dürre P.

Biotechnol Biofuels. 2017 Mar 9;10:58. doi: 10.1186/s13068-017-0742-z. eCollection 2017.

13.

Mathematical modelling of clostridial acetone-butanol-ethanol fermentation.

Millat T, Winzer K.

Appl Microbiol Biotechnol. 2017 Mar;101(6):2251-2271. doi: 10.1007/s00253-017-8137-4. Epub 2017 Feb 16. Review.

14.

Metabolic engineering of Clostridium autoethanogenum for selective alcohol production.

Liew F, Henstra AM, Kӧpke M, Winzer K, Simpson SD, Minton NP.

Metab Eng. 2017 Mar;40:104-114. doi: 10.1016/j.ymben.2017.01.007. Epub 2017 Jan 19.

15.

Development and implementation of rapid metabolic engineering tools for chemical and fuel production in Geobacillus thermoglucosidasius NCIMB 11955.

Sheng L, Kovács K, Winzer K, Zhang Y, Minton NP.

Biotechnol Biofuels. 2017 Jan 3;10:5. doi: 10.1186/s13068-016-0692-x. eCollection 2017.

16.

A genetic assay for gene essentiality in Clostridium.

Walker DJF, Heap JT, Winzer K, Minton NP.

Anaerobe. 2016 Dec;42:40-43. doi: 10.1016/j.anaerobe.2016.07.007. Epub 2016 Jul 31.

17.

Production of a functional cell wall-anchored minicellulosome by recombinant Clostridium acetobutylicum ATCC 824.

Willson BJ, Kovács K, Wilding-Steele T, Markus R, Winzer K, Minton NP.

Biotechnol Biofuels. 2016 May 23;9:109. doi: 10.1186/s13068-016-0526-x. eCollection 2016.

18.

Insights into CO2 Fixation Pathway of Clostridium autoethanogenum by Targeted Mutagenesis.

Liew F, Henstra AM, Winzer K, Köpke M, Simpson SD, Minton NP.

MBio. 2016 May 24;7(3). pii: e00427-16. doi: 10.1128/mBio.00427-16.

19.

Dendrimer mediated clustering of bacteria: improved aggregation and evaluation of bacterial response and viability.

Leire E, Amaral SP, Louzao I, Winzer K, Alexander C, Fernandez-Megia E, Fernandez-Trillo F.

Biomater Sci. 2016 Jun 24;4(6):998-1006. doi: 10.1039/c6bm00079g. Epub 2016 Apr 29.

PMID:
27127812
20.

Improving the Prognostic Ability through Better Use of Standard Clinical Data - The Nottingham Prognostic Index as an Example.

Winzer KJ, Buchholz A, Schumacher M, Sauerbrei W.

PLoS One. 2016 Mar 3;11(3):e0149977. doi: 10.1371/journal.pone.0149977. eCollection 2016.

21.

Corrigendum: Bacteria-instructed synthesis of polymers for self-selective microbial binding and labelling.

Magennis EP, Fernandez-Trillo F, Sui C, Spain SG, Bradshaw DJ, Churchley D, Mantovani G, Winzer K, Alexander C.

Nat Mater. 2016 Feb;15(2):243. doi: 10.1038/nmat4548. No abstract available.

PMID:
26796734
22.

Mutant generation by allelic exchange and genome resequencing of the biobutanol organism Clostridium acetobutylicum ATCC 824.

Ehsaan M, Kuit W, Zhang Y, Cartman ST, Heap JT, Winzer K, Minton NP.

Biotechnol Biofuels. 2016 Jan 4;9:4. doi: 10.1186/s13068-015-0410-0. eCollection 2016.

23.

Whole genome sequence and manual annotation of Clostridium autoethanogenum, an industrially relevant bacterium.

Humphreys CM, McLean S, Schatschneider S, Millat T, Henstra AM, Annan FJ, Breitkopf R, Pander B, Piatek P, Rowe P, Wichlacz AT, Woods C, Norman R, Blom J, Goesman A, Hodgman C, Barrett D, Thomas NR, Winzer K, Minton NP.

BMC Genomics. 2015 Dec 21;16:1085. doi: 10.1186/s12864-015-2287-5.

24.

Long-Term Analysis of Ab-2 (Clone SN3b) Immunoreactivity as a Prognostic Factor in Breast Carcinoma.

Winzer KJ, Bellach J, Kristiansen G.

Breast Care (Basel). 2015 Aug;10(4):273-6. doi: 10.1159/000377654. Epub 2015 Mar 26.

25.

Complete Genome Sequence of the Nonpathogenic Soil-Dwelling Bacterium Clostridium sporogenes Strain NCIMB 10696.

Kubiak AM, Poehlein A, Budd P, Kuehne SA, Winzer K, Theys J, Lambin P, Daniel R, Minton NP.

Genome Announc. 2015 Aug 20;3(4). pii: e00942-15. doi: 10.1128/genomeA.00942-15.

26.

Cationic polymer mediated bacterial clustering: Cell-adhesive properties of homo- and copolymers.

Louzao I, Sui C, Winzer K, Fernandez-Trillo F, Alexander C.

Eur J Pharm Biopharm. 2015 Sep;95(Pt A):47-62. doi: 10.1016/j.ejpb.2015.05.026. Epub 2015 Jun 9.

PMID:
26070390
27.

Genome Sequence of the Solvent-Producing Clostridium beijerinckii Strain 59B, Isolated from Staffordshire Garden Soil.

Little GT, Winzer K, Minton NP.

Genome Announc. 2015 Mar 19;3(2). pii: e00108-15. doi: 10.1128/genomeA.00108-15.

28.

Glutamate enrichment as new diagnostic opportunity in breast cancer.

Budczies J, Pfitzner BM, Györffy B, Winzer KJ, Radke C, Dietel M, Fiehn O, Denkert C.

Int J Cancer. 2015 Apr 1;136(7):1619-28. doi: 10.1002/ijc.29152. Epub 2014 Sep 4.

29.

Coenzyme A-transferase-independent butyrate re-assimilation in Clostridium acetobutylicum-evidence from a mathematical model.

Millat T, Voigt C, Janssen H, Cooksley CM, Winzer K, Minton NP, Bahl H, Fischer RJ, Wolkenhauer O.

Appl Microbiol Biotechnol. 2014 Nov;98(21):9059-72. doi: 10.1007/s00253-014-5987-x. Epub 2014 Aug 23.

PMID:
25149445
30.

Use of an Additional Diagnostic Work-up Following a Treatment Recommendation from the Preoperative Conference of the Mammography Screening Units.

Winzer KJ, Unger S, Bick U, Dieckmann F, Fallenberg E.

Geburtshilfe Frauenheilkd. 2014 Apr;74(4):370-375.

31.

Contrast-enhanced spectral mammography: Does mammography provide additional clinical benefits or can some radiation exposure be avoided?

Fallenberg EM, Dromain C, Diekmann F, Renz DM, Amer H, Ingold-Heppner B, Neumann AU, Winzer KJ, Bick U, Hamm B, Engelken F.

Breast Cancer Res Treat. 2014 Jul;146(2):371-81. doi: 10.1007/s10549-014-3023-6. Epub 2014 Jul 2.

PMID:
24986697
32.

Bacteria-instructed synthesis of polymers for self-selective microbial binding and labelling.

Magennis EP, Fernandez-Trillo F, Sui C, Spain SG, Bradshaw DJ, Churchley D, Mantovani G, Winzer K, Alexander C.

Nat Mater. 2014 Jul;13(7):748-55. doi: 10.1038/nmat3949. Epub 2014 May 11. Erratum in: Nat Mater. 2016 Feb;15(2):243.

33.

Treatment of primary breast cancer at the surgical unit of the Charité 1984-1998.

Winzer KJ, Buchholz A, Guski H, Frohberg HD, Diekmann F, Possinger K, Sauerbrei W.

Onkologie. 2013;36(12):727-36. doi: 10.1159/000356805. Epub 2013 Nov 22.

34.

Bacteria clustering by polymers induces the expression of quorum-sensing-controlled phenotypes.

Lui LT, Xue X, Sui C, Brown A, Pritchard DI, Halliday N, Winzer K, Howdle SM, Fernandez-Trillo F, Krasnogor N, Alexander C.

Nat Chem. 2013 Dec;5(12):1058-65. doi: 10.1038/nchem.1793. Epub 2013 Nov 10.

35.

Contrast-enhanced spectral mammography versus MRI: Initial results in the detection of breast cancer and assessment of tumour size.

Fallenberg EM, Dromain C, Diekmann F, Engelken F, Krohn M, Singh JM, Ingold-Heppner B, Winzer KJ, Bick U, Renz DM.

Eur Radiol. 2014 Jan;24(1):256-64. doi: 10.1007/s00330-013-3007-7. Epub 2013 Sep 19.

PMID:
24048724
36.

Impact of magnification views on the characterization of microcalcifications in digital mammography.

Fallenberg EM, Dimitrijevic L, Diekmann F, Diekmann S, Kettritz U, Poellinger A, Bick U, Winzer KJ, Engelken F, Renz DM.

Rofo. 2014 Mar;186(3):274-80. doi: 10.1055/s-0033-1350572. Epub 2013 Sep 2.

37.

Secretion and assembly of functional mini-cellulosomes from synthetic chromosomal operons in Clostridium acetobutylicum ATCC 824.

Kovács K, Willson BJ, Schwarz K, Heap JT, Jackson A, Bolam DN, Winzer K, Minton NP.

Biotechnol Biofuels. 2013 Aug 20;6(1):117. doi: 10.1186/1754-6834-6-117.

38.

The EndoPredict Gene-Expression Assay in Clinical Practice - Performance and Impact on Clinical Decisions.

Müller BM, Keil E, Lehmann A, Winzer KJ, Richter-Ehrenstein C, Prinzler J, Bangemann N, Reles A, Stadie S, Schoenegg W, Eucker J, Schmidt M, Lippek F, Jöhrens K, Pahl S, Sinn BV, Budczies J, Dietel M, Denkert C.

PLoS One. 2013 Jun 27;8(6):e68252. doi: 10.1371/journal.pone.0068252. Print 2013.

39.

Differential expression of histone deacetylases HDAC1, 2 and 3 in human breast cancer--overexpression of HDAC2 and HDAC3 is associated with clinicopathological indicators of disease progression.

Müller BM, Jana L, Kasajima A, Lehmann A, Prinzler J, Budczies J, Winzer KJ, Dietel M, Weichert W, Denkert C.

BMC Cancer. 2013 Apr 30;13:215. doi: 10.1186/1471-2407-13-215.

41.

The putative influence of the agr operon upon survival mechanisms used by Clostridium acetobutylicum.

Jabbari S, Steiner E, Heap JT, Winzer K, Minton NP, King JR.

Math Biosci. 2013 Jun;243(2):223-39. doi: 10.1016/j.mbs.2013.03.005. Epub 2013 Mar 26.

PMID:
23538287
42.

Pathogen espionage: multiple bacterial adrenergic sensors eavesdrop on host communication systems.

Karavolos MH, Winzer K, Williams P, Khan CM.

Mol Microbiol. 2013 Feb;87(3):455-65. doi: 10.1111/mmi.12110. Epub 2012 Dec 11. Review.

43.

Quorum sensing and the confusion about diffusion.

West SA, Winzer K, Gardner A, Diggle SP.

Trends Microbiol. 2012 Dec;20(12):586-94. doi: 10.1016/j.tim.2012.09.004. Epub 2012 Oct 18. Review.

44.

Targeted mutagenesis of the Clostridium acetobutylicum acetone-butanol-ethanol fermentation pathway.

Cooksley CM, Zhang Y, Wang H, Redl S, Winzer K, Minton NP.

Metab Eng. 2012 Nov;14(6):630-41. doi: 10.1016/j.ymben.2012.09.001. Epub 2012 Sep 14.

PMID:
22982601
45.

[Compliance of patients concerning recommended radiotherapy in breast cancer : Association with recurrence, age, and hormonal therapy].

Winzer KJ, Gruber C, Badakhshi H, Hinkelbein M, Denkert C.

Strahlenther Onkol. 2012 Sep;188(9):788-94. doi: 10.1007/s00066-012-0153-9. Epub 2012 Aug 5. German.

PMID:
22864807
46.

Density-dependent fitness benefits in quorum-sensing bacterial populations.

Darch SE, West SA, Winzer K, Diggle SP.

Proc Natl Acad Sci U S A. 2012 May 22;109(21):8259-63. doi: 10.1073/pnas.1118131109. Epub 2012 May 7.

47.

Integration of DNA into bacterial chromosomes from plasmids without a counter-selection marker.

Heap JT, Ehsaan M, Cooksley CM, Ng YK, Cartman ST, Winzer K, Minton NP.

Nucleic Acids Res. 2012 Apr;40(8):e59. doi: 10.1093/nar/gkr1321. Epub 2012 Jan 18.

48.

An agr quorum sensing system that regulates granulose formation and sporulation in Clostridium acetobutylicum.

Steiner E, Scott J, Minton NP, Winzer K.

Appl Environ Microbiol. 2012 Feb;78(4):1113-22. doi: 10.1128/AEM.06376-11. Epub 2011 Dec 16.

49.

Synthetic polymers for simultaneous bacterial sequestration and quorum sense interference.

Xue X, Pasparakis G, Halliday N, Winzer K, Howdle SM, Cramphorn CJ, Cameron NR, Gardner PM, Davis BG, Fernández-Trillo F, Alexander C.

Angew Chem Int Ed Engl. 2011 Oct 10;50(42):9852-6. doi: 10.1002/anie.201103130. Epub 2011 Sep 16.

PMID:
21922612
50.

Salmonella Typhi sense host neuroendocrine stress hormones and release the toxin haemolysin E.

Karavolos MH, Bulmer DM, Spencer H, Rampioni G, Schmalen I, Baker S, Pickard D, Gray J, Fookes M, Winzer K, Ivens A, Dougan G, Williams P, Khan CM.

EMBO Rep. 2011 Mar;12(3):252-8. doi: 10.1038/embor.2011.4. Epub 2011 Feb 18.

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