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Items: 1 to 50 of 242

1.

Mechanistic aspects of maltotriose-conjugate translocation to the Gram-negative bacteria cytoplasm.

Dumont E, Vergalli J, Pajovic J, Bhamidimarri SP, Morante K, Wang J, Lubriks D, Suna E, Stavenger RA, Winterhalter M, Réfrégiers M, Pagès JM.

Life Sci Alliance. 2018 Dec 28;2(1):e201800242. doi: 10.26508/lsa.201800242. eCollection 2019 Feb.

2.

Fosfomycin Permeation through the Outer Membrane Porin OmpF.

Golla VK, Sans-Serramitjana E, Pothula KR, Benier L, Bafna JA, Winterhalter M, Kleinekathöfer U.

Biophys J. 2018 Dec 8. pii: S0006-3495(18)34463-1. doi: 10.1016/j.bpj.2018.12.002. [Epub ahead of print]

PMID:
30616836
3.

Effects of H-bonds on sugar binding to chitoporin from Vibrio harveyi.

Chumjan W, Winterhalter M, Suginta W.

Biochim Biophys Acta Biomembr. 2018 Dec 19;1861(3):610-618. doi: 10.1016/j.bbamem.2018.12.012. [Epub ahead of print]

PMID:
30576623
4.

α-Amino diphenyl phosphonates as novel inhibitors of Escherichia coli ClpP protease.

Moreno-Cinos C, Sassetti E, Salado IG, Witt G, Benramdane S, Reinhardt L, Durante Cruz C, Joossens J, Van der Veken P, Brotz-Oesterhelt H, Tammela P, Winterhalter M, Gribbon P, Windshügel B, Augustyns K.

J Med Chem. 2018 Dec 20. doi: 10.1021/acs.jmedchem.8b01466. [Epub ahead of print]

PMID:
30571121
5.

A Multidisciplinary Approach toward Identification of Antibiotic Scaffolds for Acinetobacter baumannii.

Bhamidimarri SP, Zahn M, Prajapati JD, Schleberger C, Söderholm S, Hoover J, West J, Kleinekathöfer U, Bumann D, Winterhalter M, van den Berg B.

Structure. 2018 Nov 15. pii: S0969-2126(18)30382-4. doi: 10.1016/j.str.2018.10.021. [Epub ahead of print]

PMID:
30554842
6.

Endovascular Therapy versus Thrombolysis in Patients with Mild Strokes and Large Vessel Occlusions within the Anterior Circulation.

Kastrup A, Brunner F, Hildebrandt H, Roth C, Winterhalter M, Giessing C, Papanagiotou P.

Interv Neurol. 2018 Oct;7(6):431-438. doi: 10.1159/000489708. Epub 2018 Jul 11.

PMID:
30410521
7.

Translocation of small molecules through engineered outer-membrane channels from Gram-negative bacteria.

Terrasse R, Winterhalter M.

Eur Phys J E Soft Matter. 2018 Sep 24;41(9):111. doi: 10.1140/epje/i2018-11721-9.

PMID:
30238205
8.

Getting Drugs through Small Pores: Exploiting the Porins Pathway in Pseudomonas aeruginosa.

Samanta S, Bodrenko I, Acosta-Gutiérrez S, D'Agostino T, Pathania M, Ghai I, Schleberger C, Bumann D, Wagner R, Winterhalter M, van den Berg B, Ceccarelli M.

ACS Infect Dis. 2018 Oct 12;4(10):1519-1528. doi: 10.1021/acsinfecdis.8b00149. Epub 2018 Aug 8.

PMID:
30039960
9.

Combining Videolaryngoscopy With Fiber-Optic Orotracheal Intubation for Inclusion in the Nonemergency Pathway of the Difficult Airway Algorithm.

Riegel AK, Winterhalter M.

A A Pract. 2019 Jan 1;12(1):28-29. doi: 10.1213/XAA.0000000000000849.

PMID:
30036275
10.

Getting Drugs into Gram-Negative Bacteria: Rational Rules for Permeation through General Porins.

Acosta-Gutiérrez S, Ferrara L, Pathania M, Masi M, Wang J, Bodrenko I, Zahn M, Winterhalter M, Stavenger RA, Pagès JM, Naismith JH, van den Berg B, Page MGP, Ceccarelli M.

ACS Infect Dis. 2018 Oct 12;4(10):1487-1498. doi: 10.1021/acsinfecdis.8b00108. Epub 2018 Aug 17.

PMID:
29962203
11.

Unusual Constriction Zones in the Major Porins OmpU and OmpT from Vibrio cholerae.

Pathania M, Acosta-Gutierrez S, Bhamidimarri SP, Baslé A, Winterhalter M, Ceccarelli M, van den Berg B.

Structure. 2018 May 1;26(5):708-721.e4. doi: 10.1016/j.str.2018.03.010. Epub 2018 Apr 12.

PMID:
29657131
12.

Endovascular therapy versus thrombolysis in patients with large vessel occlusions within the anterior circulation aged ≥80 years.

Kastrup A, Brunner F, Hildebrandt H, Roth C, Winterhalter M, Papanagiotou P.

J Neurointerv Surg. 2018 Nov;10(11):1053-1056. doi: 10.1136/neurintsurg-2017-013732. Epub 2018 Mar 16.

PMID:
29549121
13.

Ampicillin permeation across OmpF, the major outer-membrane channel in Escherichia coli.

Ghai I, Bajaj H, Arun Bafna J, El Damrany Hussein HA, Winterhalter M, Wagner R.

J Biol Chem. 2018 May 4;293(18):7030-7037. doi: 10.1074/jbc.RA117.000705. Epub 2018 Mar 14.

PMID:
29540483
14.

Porin self-association enables cell-to-cell contact in Providencia stuartii floating communities.

El-Khatib M, Nasrallah C, Lopes J, Tran QT, Tetreau G, Basbous H, Fenel D, Gallet B, Lethier M, Bolla JM, Pagès JM, Vivaudou M, Weik M, Winterhalter M, Colletier JP.

Proc Natl Acad Sci U S A. 2018 Mar 6;115(10):E2220-E2228. doi: 10.1073/pnas.1714582115. Epub 2018 Feb 23.

15.

Enrofloxacin Permeation Pathways across the Porin OmpC.

Prajapati JD, Solano CJF, Winterhalter M, Kleinekathöfer U.

J Phys Chem B. 2018 Feb 1;122(4):1417-1426. doi: 10.1021/acs.jpcb.7b12568. Epub 2018 Jan 22.

PMID:
29307192
16.

Probing transport of fosfomycin through substrate specific OprO and OprP from Pseudomonas aeruginosa.

Citak F, Ghai I, Rosenkötter F, Benier L, Winterhalter M, Wagner R.

Biochem Biophys Res Commun. 2018 Jan 1;495(1):1454-1460. doi: 10.1016/j.bbrc.2017.11.188. Epub 2017 Dec 6.

PMID:
29198700
17.

Engineering Enhanced Pore Sizes Using FhuA Δ1-160 from E. coli Outer Membrane as Template.

Liu Z, Ghai I, Winterhalter M, Schwaneberg U.

ACS Sens. 2017 Nov 22;2(11):1619-1626. doi: 10.1021/acssensors.7b00481. Epub 2017 Nov 7.

PMID:
29052976
18.

Peptide translocation across MOMP, the major outer membrane channel from Campylobacter jejuni.

Dhanasekar NN, Aliouane S, Winterhalter M, Pagès JM, Bolla JM.

Biochem Biophys Rep. 2017 Jun 23;11:79-83. doi: 10.1016/j.bbrep.2017.06.007. eCollection 2017 Sep.

19.

Characterization of Ciprofloxacin Permeation Pathways across the Porin OmpC Using Metadynamics and a String Method.

Prajapati JD, Fernández Solano CJ, Winterhalter M, Kleinekathöfer U.

J Chem Theory Comput. 2017 Sep 12;13(9):4553-4566. doi: 10.1021/acs.jctc.7b00467. Epub 2017 Aug 30.

PMID:
28816443
20.

Biophysical characterization of E. coli TolC interaction with the known blocker hexaamminecobalt.

Gilardi A, Bhamidimarri SP, Brönstrup M, Bilitewski U, Marreddy RKR, Pos KM, Benier L, Gribbon P, Winterhalter M, Windshügel B.

Biochim Biophys Acta Gen Subj. 2017 Nov;1861(11 Pt A):2702-2709. doi: 10.1016/j.bbagen.2017.07.014. Epub 2017 Jul 23.

PMID:
28746830
21.

Sensing Single Molecule Penetration into Nanopores: Pushing the Time Resolution to the Diffusion Limit.

Bodrenko IV, Wang J, Salis S, Winterhalter M, Ceccarelli M.

ACS Sens. 2017 Aug 25;2(8):1184-1190. doi: 10.1021/acssensors.7b00311. Epub 2017 Jul 28.

PMID:
28730802
22.

Polydopamine Coating To Stabilize a Free-Standing Lipid Bilayer for Channel Sensing.

Neveshkin A, Citak F, Ball V, Winterhalter M.

Langmuir. 2017 Jul 25;33(29):7256-7262. doi: 10.1021/acs.langmuir.7b01959. Epub 2017 Jul 11.

PMID:
28657327
23.

Correction to Ion Channels Made from a Single Membrane-Spanning DNA Duplex.

Göpfrich K, Li CY, Mames I, Bhamidimarri SP, Ricci M, Yoo J, Mames A, Ohmann A, Winterhalter M, Stulz E, Aksimentiev A, Keyser UF.

Nano Lett. 2017 Jul 12;17(7):4548. doi: 10.1021/acs.nanolett.7b02430. Epub 2017 Jun 13. No abstract available.

24.

Porin flexibility in Providencia stuartii: cell-surface-exposed loops L5 and L7 are markers of Providencia porin OmpPst1.

Tran QT, Maigre L, D'Agostino T, Ceccarelli M, Winterhalter M, Pagès JM, Davin-Regli A.

Res Microbiol. 2017 Oct;168(8):685-699. doi: 10.1016/j.resmic.2017.05.003. Epub 2017 May 30.

PMID:
28576703
25.

THRIVE score predicts clinical and radiological outcome after endovascular therapy or thrombolysis in patients with anterior circulation stroke in everyday clinical practice.

Kastrup A, Brunner F, Hildebrandt H, Roth C, Winterhalter M, Gießing C, Papanagiotou P.

Eur J Neurol. 2017 Aug;24(8):1032-1039. doi: 10.1111/ene.13328. Epub 2017 May 29.

PMID:
28556351
26.

Effectiveness of various formulations of local anesthetics and additives for topical anesthesia - a prospective, randomized, double-blind, placebo-controlled study.

Weilbach C, Hoppe C, Karst M, Winterhalter M, Raymondos K, Schultz A, Rahe-Meyer N.

J Pain Res. 2017 May 10;10:1105-1109. doi: 10.2147/JPR.S131029. eCollection 2017.

27.

Bacterial Outer Membrane Porins as Electrostatic Nanosieves: Exploring Transport Rules of Small Polar Molecules.

Bajaj H, Acosta Gutierrez S, Bodrenko I, Malloci G, Scorciapino MA, Winterhalter M, Ceccarelli M.

ACS Nano. 2017 Jun 27;11(6):5465-5473. doi: 10.1021/acsnano.6b08613. Epub 2017 May 12.

28.

Understanding Carbapenem Translocation through OccD3 (OpdP) of Pseudomonas aeruginosa.

Soundararajan G, Bhamidimarri SP, Winterhalter M.

ACS Chem Biol. 2017 Jun 16;12(6):1656-1664. doi: 10.1021/acschembio.6b01150. Epub 2017 May 4.

PMID:
28440622
29.

Protein A Functionalized Polyelectrolyte Microcapsules as a Universal Platform for Enhanced Targeting of Cell Surface Receptors.

Kolesnikova TA, Kiragosyan G, Le TH, Springer S, Winterhalter M.

ACS Appl Mater Interfaces. 2017 Apr 5;9(13):11506-11517. doi: 10.1021/acsami.7b01313. Epub 2017 Mar 27.

PMID:
28290659
30.

Single Residue Acts as Gate in OccK Channels.

Pothula KR, Dhanasekar NN, Lamichhane U, Younas F, Pletzer D, Benz R, Winterhalter M, Kleinekathöfer U.

J Phys Chem B. 2017 Mar 30;121(12):2614-2621. doi: 10.1021/acs.jpcb.7b01787. Epub 2017 Mar 21.

PMID:
28257208
31.

General Method to Determine the Flux of Charged Molecules through Nanopores Applied to β-Lactamase Inhibitors and OmpF.

Ghai I, Pira A, Scorciapino MA, Bodrenko I, Benier L, Ceccarelli M, Winterhalter M, Wagner R.

J Phys Chem Lett. 2017 Mar 16;8(6):1295-1301. doi: 10.1021/acs.jpclett.7b00062. Epub 2017 Mar 6.

PMID:
28240914
32.

Probing transport of charged β-lactamase inhibitors through OmpC, a membrane channel from E. coli.

Ghai I, Winterhalter M, Wagner R.

Biochem Biophys Res Commun. 2017 Feb 26;484(1):51-55. doi: 10.1016/j.bbrc.2017.01.076. Epub 2017 Jan 18.

PMID:
28109883
33.

Mechanisms of intrinsic resistance and acquired susceptibility of Pseudomonas aeruginosa isolated from cystic fibrosis patients to temocillin, a revived antibiotic.

Chalhoub H, Pletzer D, Weingart H, Braun Y, Tunney MM, Elborn JS, Rodriguez-Villalobos H, Plésiat P, Kahl BC, Denis O, Winterhalter M, Tulkens PM, Van Bambeke F.

Sci Rep. 2017 Jan 16;7:40208. doi: 10.1038/srep40208.

34.

Structural basis for nutrient acquisition by dominant members of the human gut microbiota.

Glenwright AJ, Pothula KR, Bhamidimarri SP, Chorev DS, Baslé A, Firbank SJ, Zheng H, Robinson CV, Winterhalter M, Kleinekathöfer U, Bolam DN, van den Berg B.

Nature. 2017 Jan 19;541(7637):407-411. doi: 10.1038/nature20828. Epub 2017 Jan 11.

35.

Correlated trapping of sugar molecules by the trimeric protein channel  chitoporin.

Suginta W, Winterhalter M, Smith MF.

Biochim Biophys Acta. 2016 Dec;1858(12):3032-3040. doi: 10.1016/j.bbamem.2016.09.007. Epub 2016 Sep 14.

36.

MOMP from Campylobacter jejuni Is a Trimer of 18-Stranded β-Barrel Monomers with a Ca2+ Ion Bound at the Constriction Zone.

Ferrara LGM, Wallat GD, Moynié L, Dhanasekar NN, Aliouane S, Acosta-Gutiérrez S, Pagès JM, Bolla JM, Winterhalter M, Ceccarelli M, Naismith JH.

J Mol Biol. 2016 Nov 6;428(22):4528-4543. doi: 10.1016/j.jmb.2016.09.021. Epub 2016 Sep 30.

37.

Impact of ASPECTS on computed tomography angiography source images on outcome after thrombolysis or endovascular therapy in large vessel occlusions.

Wasser K, Papanagiotou P, Brunner F, Hildebrandt H, Winterhalter M, Roth C, Kastrup A.

Eur J Neurol. 2016 Nov;23(11):1599-1605. doi: 10.1111/ene.13068. Epub 2016 Jul 14.

PMID:
27414987
38.

Large-Conductance Transmembrane Porin Made from DNA Origami.

Göpfrich K, Li CY, Ricci M, Bhamidimarri SP, Yoo J, Gyenes B, Ohmann A, Winterhalter M, Aksimentiev A, Keyser UF.

ACS Nano. 2016 Sep 27;10(9):8207-14. doi: 10.1021/acsnano.6b03759. Epub 2016 Aug 23.

39.

Ion Channels Made from a Single Membrane-Spanning DNA Duplex.

Göpfrich K, Li CY, Mames I, Bhamidimarri SP, Ricci M, Yoo J, Mames A, Ohmann A, Winterhalter M, Stulz E, Aksimentiev A, Keyser UF.

Nano Lett. 2016 Jul 13;16(7):4665-9. doi: 10.1021/acs.nanolett.6b02039. Epub 2016 Jun 29. Erratum in: Nano Lett. 2017 Jul 12;17(7):4548.

40.

Draft Genome Sequence of Dietzia maris DSM 43672, a Gram-Positive Bacterium of the Mycolata Group.

Ganguly S, Jimenez-Galisteo G, Pletzer D, Winterhalter M, Benz R, Viñas M.

Genome Announc. 2016 Jun 9;4(3). pii: e00542-16. doi: 10.1128/genomeA.00542-16.

41.

Endovascular therapy versus thrombolysis in patients with anterior circulation stroke in everyday clinical practice.

Kastrup A, Brunner F, Wasser K, Hildebrandt H, Roth C, Winterhalter M, Papanagiotou P.

Int J Stroke. 2016 Jul;11(5):544-8. doi: 10.1177/1747493016641948. Epub 2016 Apr 7.

PMID:
27056966
42.

Role of Electroosmosis in the Permeation of Neutral Molecules: CymA and Cyclodextrin as an Example.

Bhamidimarri SP, Prajapati JD, van den Berg B, Winterhalter M, Kleinekathöfer U.

Biophys J. 2016 Feb 2;110(3):600-611. doi: 10.1016/j.bpj.2015.12.027.

43.

Structural Insights into Outer Membrane Permeability of Acinetobacter baumannii.

Zahn M, Bhamidimarri SP, Baslé A, Winterhalter M, van den Berg B.

Structure. 2016 Feb 2;24(2):221-31. doi: 10.1016/j.str.2015.12.009. Epub 2016 Jan 21.

44.

Molecular Basis of Filtering Carbapenems by Porins from β-Lactam-resistant Clinical Strains of Escherichia coli.

Bajaj H, Scorciapino MA, Moynié L, Page MG, Naismith JH, Ceccarelli M, Winterhalter M.

J Biol Chem. 2016 Feb 5;291(6):2837-47. doi: 10.1074/jbc.M115.690156. Epub 2015 Dec 8.

45.

Toxins Secreted by Bacillus Isolated from Lung Adenocarcinomas Favor the Penetration of Toxic Substances.

Merlos A, Rodríguez P, Bárcena-Uribarri I, Winterhalter M, Benz R, Vinuesa T, Moya JA, Viñas M.

Front Microbiol. 2015 Nov 23;6:1301. doi: 10.3389/fmicb.2015.01301. eCollection 2015.

46.

The Innovative Medicines Initiative's New Drugs for Bad Bugs programme: European public-private partnerships for the development of new strategies to tackle antibiotic resistance.

Kostyanev T, Bonten MJ, O'Brien S, Steel H, Ross S, François B, Tacconelli E, Winterhalter M, Stavenger RA, Karlén A, Harbarth S, Hackett J, Jafri HS, Vuong C, MacGowan A, Witschi A, Angyalosi G, Elborn JS, deWinter R, Goossens H.

J Antimicrob Chemother. 2016 Feb;71(2):290-5. doi: 10.1093/jac/dkv339. Epub 2015 Nov 15. Review.

PMID:
26568581
47.

Quantification of Fluoroquinolone Uptake through the Outer Membrane Channel OmpF of Escherichia coli.

Cama J, Bajaj H, Pagliara S, Maier T, Braun Y, Winterhalter M, Keyser UF.

J Am Chem Soc. 2015 Nov 4;137(43):13836-43. doi: 10.1021/jacs.5b08960. Epub 2015 Oct 27.

PMID:
26478537
48.

Polydopamine Films from the Forgotten Air/Water Interface.

Ponzio F, Payamyar P, Schneider A, Winterhalter M, Bour J, Addiego F, Krafft MP, Hemmerle J, Ball V.

J Phys Chem Lett. 2014 Oct 2;5(19):3436-40. doi: 10.1021/jz501842r. Epub 2014 Sep 24.

PMID:
26278460
49.

Crystal structure of a COG4313 outer membrane channel.

van den Berg B, Bhamidimarri SP, Winterhalter M.

Sci Rep. 2015 Jul 7;5:11927. doi: 10.1038/srep11927.

50.

Chitoporin from the Marine Bacterium Vibrio harveyi: PROBING THE ESSENTIAL ROLES OF TRP136 AT THE SURFACE OF THE CONSTRICTION ZONE.

Chumjan W, Winterhalter M, Schulte A, Benz R, Suginta W.

J Biol Chem. 2015 Jul 31;290(31):19184-96. doi: 10.1074/jbc.M115.660530. Epub 2015 Jun 16.

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