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Items: 19


The multifaceted roles of tumor-associated proteases and harnessing their activity for prodrug activation.

Vasiljeva O, Hostetter DR, Moore SJ, Winter MB.

Biol Chem. 2019 Apr 22. pii: /j/bchm.ahead-of-print/hsz-2018-0451/hsz-2018-0451.xml. doi: 10.1515/hsz-2018-0451. [Epub ahead of print] Review.


Predicting CD4 T-cell epitopes based on antigen cleavage, MHCII presentation, and TCR recognition.

Schneidman-Duhovny D, Khuri N, Dong GQ, Winter MB, Shifrut E, Friedman N, Craik CS, Pratt KP, Paz P, Aswad F, Sali A.

PLoS One. 2018 Nov 6;13(11):e0206654. doi: 10.1371/journal.pone.0206654. eCollection 2018.


Impacts of salvage logging on biodiversity: a meta-analysis.

Thorn S, Bässler C, Brandl R, Burton PJ, Cahall R, Campbell JL, Castro J, Choi CY, Cobb T, Donato DC, Durska E, Fontaine JB, Gauthier S, Hebert C, Hothorn T, Hutto RL, Lee EJ, Leverkus AB, Lindenmayer DB, Obrist MK, Rost J, Seibold S, Seidl R, Thom D, Waldron K, Wermelinger B, Winter MB, Zmihorski M, Müller J.

J Appl Ecol. 2018 Jan;55(1):279-289. doi: 10.1111/1365-2664.12945. Epub 2017 Jul 5.


Immunoproteasome functions explained by divergence in cleavage specificity and regulation.

Winter MB, La Greca F, Arastu-Kapur S, Caiazza F, Cimermancic P, Buchholz TJ, Anderl JL, Ravalin M, Bohn MF, Sali A, O'Donoghue AJ, Craik CS.

Elife. 2017 Nov 28;6. pii: e27364. doi: 10.7554/eLife.27364.


Global substrate specificity profiling of post-translational modifying enzymes.

Ivry SL, Meyer NO, Winter MB, Bohn MF, Knudsen GM, O'Donoghue AJ, Craik CS.

Protein Sci. 2018 Mar;27(3):584-594. doi: 10.1002/pro.3352. Epub 2017 Dec 8. Review.


The Rational Design of Therapeutic Peptides for Aminopeptidase N using a Substrate-Based Approach.

Joshi S, Chen L, Winter MB, Lin YL, Yang Y, Shapovalova M, Smith PM, Liu C, Li F, LeBeau AM.

Sci Rep. 2017 May 2;7(1):1424. doi: 10.1038/s41598-017-01542-5.


Multiplex Substrate Profiling by Mass Spectrometry for Kinases as a Method for Revealing Quantitative Substrate Motifs.

Meyer NO, O'Donoghue AJ, Schulze-Gahmen U, Ravalin M, Moss SM, Winter MB, Knudsen GM, Craik CS.

Anal Chem. 2017 Apr 18;89(8):4550-4558. doi: 10.1021/acs.analchem.6b05002. Epub 2017 Apr 4.


Global Identification of Biofilm-Specific Proteolysis in Candida albicans.

Winter MB, Salcedo EC, Lohse MB, Hartooni N, Gulati M, Sanchez H, Takagi J, Hube B, Andes DR, Johnson AD, Craik CS, Nobile CJ.

MBio. 2016 Sep 13;7(5). pii: e01514-16. doi: 10.1128/mBio.01514-16.


Imaging active urokinase plasminogen activator in prostate cancer.

LeBeau AM, Sevillano N, Markham K, Winter MB, Murphy ST, Hostetter DR, West J, Lowman H, Craik CS, VanBrocklin HF.

Cancer Res. 2015 Apr 1;75(7):1225-35. doi: 10.1158/0008-5472.CAN-14-2185. Epub 2015 Feb 11.


Subnanometre-resolution electron cryomicroscopy structure of a heterodimeric ABC exporter.

Kim J, Wu S, Tomasiak TM, Mergel C, Winter MB, Stiller SB, Robles-Colmanares Y, Stroud RM, Tampé R, Craik CS, Cheng Y.

Nature. 2015 Jan 15;517(7534):396-400. doi: 10.1038/nature13872. Epub 2014 Nov 2.


An Escherichia coli expression-based approach for porphyrin substitution in heme proteins.

Winter MB, Woodward JJ, Marletta MA.

Methods Mol Biol. 2013;987:95-106. doi: 10.1007/978-1-62703-321-3_8.


Porphyrin-substituted H-NOX proteins as high-relaxivity MRI contrast agents.

Winter MB, Klemm PJ, Phillips-Piro CM, Raymond KN, Marletta MA.

Inorg Chem. 2013 Mar 4;52(5):2277-9. doi: 10.1021/ic302685h. Epub 2013 Feb 8.


Tunnels modulate ligand flux in a heme nitric oxide/oxygen binding (H-NOX) domain.

Winter MB, Herzik MA Jr, Kuriyan J, Marletta MA.

Proc Natl Acad Sci U S A. 2011 Oct 25;108(43):E881-9. doi: 10.1073/pnas.1114038108. Epub 2011 Oct 12.


Probing domain interactions in soluble guanylate cyclase.

Derbyshire ER, Winter MB, Ibrahim M, Deng S, Spiro TG, Marletta MA.

Biochemistry. 2011 May 24;50(20):4281-90. doi: 10.1021/bi200341b. Epub 2011 May 3.


Structure and properties of a bis-histidyl ligated globin from Caenorhabditis elegans.

Yoon J, Herzik MA Jr, Winter MB, Tran R, Olea C Jr, Marletta MA.

Biochemistry. 2010 Jul 13;49(27):5662-70. doi: 10.1021/bi100710a.


Ru-porphyrin protein scaffolds for sensing O2.

Winter MB, McLaurin EJ, Reece SY, Olea C Jr, Nocera DG, Marletta MA.

J Am Chem Soc. 2010 Apr 28;132(16):5582-3. doi: 10.1021/ja101527r.


4,4-Difluorinated analogues of l-arginine and N(G)-hydroxy-l-arginine as mechanistic probes for nitric oxide synthase.

Martin NI, Woodward JJ, Winter MB, Marletta MA.

Bioorg Med Chem Lett. 2009 Mar 15;19(6):1758-62. doi: 10.1016/j.bmcl.2009.01.076. Epub 2009 Feb 18.


Experimental approaches to microarray analysis of tumor samples.

Furge LL, Winter MB, Meyers JI, Furge KA.

Biochem Mol Biol Educ. 2008 Mar;36(2):149-52. doi: 10.1002/bmb.20161.


Design and synthesis of C5 methylated L-arginine analogues as active site probes for nitric oxide synthase.

Martin NI, Woodward JJ, Winter MB, Beeson WT, Marletta MA.

J Am Chem Soc. 2007 Oct 17;129(41):12563-70. Epub 2007 Sep 25.


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