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Items: 1 to 50 of 162

1.
2.

Enhancing Patient Outcomes while Containing Costs after Complex Abdominal Operation: A Randomized Controlled Trial of the Whipple Accelerated Recovery Pathway.

Lavu H, McCall NS, Winter JM, Burkhart RA, Pucci M, Leiby BE, Yeo TP, Cannaday S, Yeo CJ.

J Am Coll Surg. 2019 Jan 17. pii: S1072-7515(19)30043-2. doi: 10.1016/j.jamcollsurg.2018.12.032. [Epub ahead of print]

PMID:
30660818
3.

Surgeon-Led Imaging Review for Patients with Periampullary Disease: An Important Aspect of the Preoperative Consultation.

Latona JA, Tannouri S, Yeo TP, Cannaday S, Lavu H, Winter JM, Yeo CJ.

J Pancreat Cancer. 2018 Sep 1;4(1):52-59. doi: 10.1089/pancan.2018.0010. eCollection 2018.

4.

Precious Data: Interim Report from the Jefferson Pancreas Tumor Registry.

Yeo TP, Lavu H, Nevler A, Brumbaugh J, Vicchairelli D, Winter JM, Brody JR, Yeo CJ.

J Pancreat Cancer. 2018 Jun 1;4(1):17-24. doi: 10.1089/pancan.2018.0004. eCollection 2018.

5.

Metabolic Dependencies in Pancreatic Cancer.

Vaziri-Gohar A, Zarei M, Brody JR, Winter JM.

Front Oncol. 2018 Dec 12;8:617. doi: 10.3389/fonc.2018.00617. eCollection 2018. Review.

6.

Charles Heber McBurney-McBurney and His Point to Make.

Ang SM, Tham E, Cowan SW, Yeo CJ, Winter JM.

Am Surg. 2018 Dec 1;84(12):1847-1849. No abstract available.

PMID:
30606337
7.

Host IDO2 Gene Status Influences Tumor Progression and Radiotherapy Response in KRAS-Driven Sporadic Pancreatic Cancers.

Nevler A, Muller AJ, Sutanto-Ward E, DuHadaway JB, Nagatomo K, Londin E, O'Hayer K, Cozzitorto JA, Lavu H, Yeo TP, Curtis M, Villatoro T, Leiby BE, Mandik-Nayak L, Winter JM, Yeo CJ, Prendergast GC, Brody JR.

Clin Cancer Res. 2019 Jan 15;25(2):724-734. doi: 10.1158/1078-0432.CCR-18-0814. Epub 2018 Sep 28.

PMID:
30266763
8.

RNA-Binding Protein HuR Regulates Both Mutant and Wild-Type IDH1 in IDH1-Mutated Cancer.

Zarei M, Lal S, Vaziri-Gohar A, O'Hayer K, Gunda V, Singh PK, Brody JR, Winter JM.

Mol Cancer Res. 2019 Feb;17(2):508-520. doi: 10.1158/1541-7786.MCR-18-0557. Epub 2018 Sep 28.

PMID:
30266754
9.

Clinical Implications of Extensive Lymph Node Metastases for Resected Pancreatic Cancer.

Lowder CY, Metkus J, Epstein J, Kozak GM, Lavu H, Yeo CJ, Winter JM.

Ann Surg Oncol. 2018 Dec;25(13):4004-4011. doi: 10.1245/s10434-018-6763-4. Epub 2018 Sep 17.

PMID:
30225835
10.

Pancreatic Cancer-Associated Depression: A Case Report and Review of the Literature.

Barnes AF, Yeo TP, Leiby B, Kay A, Winter JM.

Pancreas. 2018 Oct;47(9):1065-1077. doi: 10.1097/MPA.0000000000001148.

PMID:
30199487
11.

Prostate cancer susceptibility gene HIST1H1A is a modulator of androgen receptor signaling and epithelial to mesenchymal transition.

Williams KA, Lee M, Winter JM, Gildea DE, Calagua C, Curry NL, Lichtenberg J, Ye H, Crawford NPS.

Oncotarget. 2018 Jun 19;9(47):28532-28546. doi: 10.18632/oncotarget.25536. eCollection 2018 Jun 19.

12.

The Combination of Pancreas Texture and Postoperative Serum Amylase in Predicting Pancreatic Fistula Risk.

Chen CB, McCall NS, Pucci MJ, Leiby B, Dabbish N, Winter JM, Yeo CJ, Lavu H.

Am Surg. 2018 Jun 1;84(6):889-896.

PMID:
29981620
13.

Modifier locus mapping of a transgenic F2 mouse population identifies CCDC115 as a novel aggressive prostate cancer modifier gene in humans.

Winter JM, Curry NL, Gildea DM, Williams KA, Lee M, Hu Y, Crawford NPS.

BMC Genomics. 2018 Jun 11;19(1):450. doi: 10.1186/s12864-018-4827-2.

14.

Organoid Profiling Identifies Common Responders to Chemotherapy in Pancreatic Cancer.

Tiriac H, Belleau P, Engle DD, Plenker D, Deschênes A, Somerville TDD, Froeling FEM, Burkhart RA, Denroche RE, Jang GH, Miyabayashi K, Young CM, Patel H, Ma M, LaComb JF, Palmaira RLD, Javed AA, Huynh JC, Johnson M, Arora K, Robine N, Shah M, Sanghvi R, Goetz AB, Lowder CY, Martello L, Driehuis E, LeComte N, Askan G, Iacobuzio-Donahue CA, Clevers H, Wood LD, Hruban RH, Thompson E, Aguirre AJ, Wolpin BM, Sasson A, Kim J, Wu M, Bucobo JC, Allen P, Sejpal DV, Nealon W, Sullivan JD, Winter JM, Gimotty PA, Grem JL, DiMaio DJ, Buscaglia JM, Grandgenett PM, Brody JR, Hollingsworth MA, O'Kane GM, Notta F, Kim E, Crawford JM, Devoe C, Ocean A, Wolfgang CL, Yu KH, Li E, Vakoc CR, Hubert B, Fischer SE, Wilson JM, Moffitt R, Knox J, Krasnitz A, Gallinger S, Tuveson DA.

Cancer Discov. 2018 Sep;8(9):1112-1129. doi: 10.1158/2159-8290.CD-18-0349. Epub 2018 May 31.

PMID:
29853643
15.

A Sub-Type of Familial Pancreatic Cancer: Evidence and Implications of Loss-of-Function Polymorphisms in Indoleamine-2,3-Dioxygenase-2.

Nevler A, Muller AJ, Cozzitorto JA, Goetz A, Winter JM, Yeo TP, Lavu H, Yeo CJ, Prendergast GC, Brody JR.

J Am Coll Surg. 2018 Apr;226(4):596-603. doi: 10.1016/j.jamcollsurg.2017.12.052. Epub 2018 Feb 7.

16.

Dysfunctional sarcomere contractility contributes to muscle weakness in ACTA1-related nemaline myopathy (NEM3).

Joureau B, de Winter JM, Conijn S, Bogaards SJP, Kovacevic I, Kalganov A, Persson M, Lindqvist J, Stienen GJM, Irving TC, Ma W, Yuen M, Clarke NF, Rassier DE, Malfatti E, Romero NB, Beggs AH, Ottenheijm CAC.

Ann Neurol. 2018 Feb;83(2):269-282. doi: 10.1002/ana.25144. Epub 2018 Feb 6.

17.

Common Hepatic Artery Abutment or Encasement Is an Adverse Prognostic Factor in Patients with Borderline and Unresectable Pancreatic Cancer.

Kozak GM, Epstein JD, Deshmukh SP, Scott BB, Keith SW, Lavu H, Yeo CJ, Winter JM.

J Gastrointest Surg. 2018 Feb;22(2):288-294. doi: 10.1007/s11605-017-3595-7. Epub 2017 Nov 14.

PMID:
29139084
18.

Small GTPase ARF6 controls VEGFR2 trafficking and signaling in diabetic retinopathy.

Zhu W, Shi DS, Winter JM, Rich BE, Tong Z, Sorensen LK, Zhao H, Huang Y, Tai Z, Mleynek TM, Yoo JH, Dunn C, Ling J, Bergquist JA, Richards JR, Jiang A, Lesniewski LA, Hartnett ME, Ward DM, Mueller AL, Ostanin K, Thomas KR, Odelberg SJ, Li DY.

J Clin Invest. 2017 Dec 1;127(12):4569-4582. doi: 10.1172/JCI91770. Epub 2017 Oct 23.

19.

Total parenteral nutrition in patients following pancreaticoduodenectomy: lessons from 1184 patients.

Worsh CE, Tatarian T, Singh A, Pucci MJ, Winter JM, Yeo CJ, Lavu H.

J Surg Res. 2017 Oct;218:156-161. doi: 10.1016/j.jss.2017.05.057. Epub 2017 Jun 16.

PMID:
28985843
20.

Calcium influx through TRPV4 channels modulates the adherens contacts between retinal microvascular endothelial cells.

Phuong TTT, Redmon SN, Yarishkin O, Winter JM, Li DY, Križaj D.

J Physiol. 2017 Nov 15;595(22):6869-6885. doi: 10.1113/JP275052. Epub 2017 Oct 25.

21.

A Prospective Randomized Multicenter Trial of Distal Pancreatectomy With and Without Routine Intraperitoneal Drainage.

Van Buren G 2nd, Bloomston M, Schmidt CR, Behrman SW, Zyromski NJ, Ball CG, Morgan KA, Hughes SJ, Karanicolas PJ, Allendorf JD, Vollmer CM Jr, Ly Q, Brown KM, Velanovich V, Winter JM, McElhany AL, Muscarella P 2nd, Schmidt CM, House MG, Dixon E, Dillhoff ME, Trevino JG, Hallet J, Coburn NSG, Nakeeb A, Behrns KE, Sasson AR, Ceppa EP, Abdel-Misih SRZ, Riall TS, Silberfein EJ, Ellison EC, Adams DB, Hsu C, Tran Cao HS, Mohammed S, Villafañe-Ferriol N, Barakat O, Massarweh NN, Chai C, Mendez-Reyes JE, Fang A, Jo E, Mo Q, Fisher WE.

Ann Surg. 2017 Sep;266(3):421-431. doi: 10.1097/SLA.0000000000002375.

PMID:
28692468
22.

Posttranscriptional Regulation of PARG mRNA by HuR Facilitates DNA Repair and Resistance to PARP Inhibitors.

Chand SN, Zarei M, Schiewer MJ, Kamath AR, Romeo C, Lal S, Cozzitorto JA, Nevler A, Scolaro L, Londin E, Jiang W, Meisner-Kober N, Pishvaian MJ, Knudsen KE, Yeo CJ, Pascal JM, Winter JM, Brody JR.

Cancer Res. 2017 Sep 15;77(18):5011-5025. doi: 10.1158/0008-5472.CAN-16-2704. Epub 2017 Jul 7.

23.

Bonnevillamides, Linear Heptapeptides Isolated from a Great Salt Lake-Derived Streptomyces sp.

Wu G, Nielson JR, Peterson RT, Winter JM.

Mar Drugs. 2017 Jun 24;15(7). pii: E195. doi: 10.3390/md15070195.

24.

Posttranscriptional Upregulation of IDH1 by HuR Establishes a Powerful Survival Phenotype in Pancreatic Cancer Cells.

Zarei M, Lal S, Parker SJ, Nevler A, Vaziri-Gohar A, Dukleska K, Mambelli-Lisboa NC, Moffat C, Blanco FF, Chand SN, Jimbo M, Cozzitorto JA, Jiang W, Yeo CJ, Londin ER, Seifert EL, Metallo CM, Brody JR, Winter JM.

Cancer Res. 2017 Aug 15;77(16):4460-4471. doi: 10.1158/0008-5472.CAN-17-0015. Epub 2017 Jun 26.

25.

Microscopic lymphovascular invasion is an independent predictor of survival in resected pancreatic ductal adenocarcinoma.

Epstein JD, Kozak G, Fong ZV, He J, Javed AA, Joneja U, Jiang W, Ferrone CR, Lillemoe KD, Cameron JL, Weiss MJ, Lavu H, Yeo CJ, Fernandez-Del Castillo C, Wolfgang CL, Winter JM.

J Surg Oncol. 2017 Nov;116(6):658-664. doi: 10.1002/jso.24723. Epub 2017 Jun 19.

PMID:
28628722
26.

Sarcomere Dysfunction in Nemaline Myopathy.

de Winter JM, Ottenheijm CAC.

J Neuromuscul Dis. 2017;4(2):99-113. doi: 10.3233/JND-160200.

27.

Collaborative Biosynthesis of Maleimide- and Succinimide-Containing Natural Products by Fungal Polyketide Megasynthases.

Sato M, Dander JE, Sato C, Hung YS, Gao SS, Tang MC, Hang L, Winter JM, Garg NK, Watanabe K, Tang Y.

J Am Chem Soc. 2017 Apr 19;139(15):5317-5320. doi: 10.1021/jacs.7b02432. Epub 2017 Apr 5.

28.

CRISPR Knockout of the HuR Gene Causes a Xenograft Lethal Phenotype.

Lal S, Cheung EC, Zarei M, Preet R, Chand SN, Mambelli-Lisboa NC, Romeo C, Stout MC, Londin E, Goetz A, Lowder CY, Nevler A, Yeo CJ, Campbell PM, Winter JM, Dixon DA, Brody JR.

Mol Cancer Res. 2017 Jun;15(6):696-707. doi: 10.1158/1541-7786.MCR-16-0361. Epub 2017 Feb 27.

29.

A two-faced cysteine residue modulates skeletal muscle contraction. Focus on "S-nitrosylation and S-glutathionylation of Cys134 on troponin I have opposing competitive actions on Ca2+ sensitivity in rat fast-twitch muscle fibers.

de Winter JM, Ottenheijm CA.

Am J Physiol Cell Physiol. 2017 Mar 1;312(3):C314-C315. doi: 10.1152/ajpcell.00009.2017. Epub 2017 Feb 1. No abstract available.

30.

Enzymatic Halogenation and Dehalogenation Reactions: Pervasive and Mechanistically Diverse.

Agarwal V, Miles ZD, Winter JM, Eustáquio AS, El Gamal AA, Moore BS.

Chem Rev. 2017 Apr 26;117(8):5619-5674. doi: 10.1021/acs.chemrev.6b00571. Epub 2017 Jan 20. Review.

31.

The small GTPase ARF6 regulates protein trafficking to control cellular function during development and in disease.

Grossmann AH, Zhao H, Jenkins N, Zhu W, Richards JR, Yoo JH, Winter JM, Rich B, Mleynek TM, Li DY, Odelberg SJ.

Small GTPases. 2016 Dec 21:1-12. doi: 10.1080/21541248.2016.1259710. [Epub ahead of print]

32.

Mapping Complex Traits in a Diversity Outbred F1 Mouse Population Identifies Germline Modifiers of Metastasis in Human Prostate Cancer.

Winter JM, Gildea DE, Andreas JP, Gatti DM, Williams KA, Lee M, Hu Y, Zhang S; NISC Comparative Sequencing Program, Mullikin JC, Wolfsberg TG, McDonnell SK, Fogarty ZC, Larson MC, French AJ, Schaid DJ, Thibodeau SN, Churchill GA, Crawford NP.

Cell Syst. 2017 Jan 25;4(1):31-45.e6. doi: 10.1016/j.cels.2016.10.018. Epub 2016 Dec 1.

33.

Cytoplasmic HuR Status Predicts Disease-free Survival in Resected Pancreatic Cancer: A Post-hoc Analysis From the International Phase III ESPAC-3 Clinical Trial.

Tatarian T, Jiang W, Leiby BE, Grigoli A, Jimbo M, Dabbish N, Neoptolemos JP, Greenhalf W, Costello E, Ghaneh P, Halloran C, Palmer D, Buchler M, Yeo CJ, Winter JM, Brody JR.

Ann Surg. 2018 Feb;267(2):364-369. doi: 10.1097/SLA.0000000000002088.

PMID:
27893535
34.

Muscle weakness in respiratory and peripheral skeletal muscles in a mouse model for nebulin-based nemaline myopathy.

Joureau B, de Winter JM, Stam K, Granzier H, Ottenheijm CA.

Neuromuscul Disord. 2017 Jan;27(1):83-89. doi: 10.1016/j.nmd.2016.10.004. Epub 2016 Oct 25.

PMID:
27890461
35.

Genetics of Pancreatic Cancer and Its Implications on Therapy.

Tatarian T, Winter JM.

Surg Clin North Am. 2016 Dec;96(6):1207-1221. doi: 10.1016/j.suc.2016.07.014. Review.

PMID:
27865273
36.

Pneumonia is associated with a high risk of mortality after pancreaticoduodenectomy.

Nagle RT, Leiby BE, Lavu H, Rosato EL, Yeo CJ, Winter JM.

Surgery. 2017 Apr;161(4):959-967. doi: 10.1016/j.surg.2016.09.028. Epub 2016 Nov 8.

PMID:
27836210
37.

Intraoperative Frozen Section Analysis of the Pancreas: A Case Report and Review of the Literature.

Bonaroti JW, Doane S, McCue PA, Winter JM.

Case Rep Pancreat Cancer. 2016 Nov 1;2(1):71-74. doi: 10.1089/crpc.2016.0014. eCollection 2016.

38.

Dietary butyrylated high-amylose starch reduces azoxymethane-induced colonic O(6)-methylguanine adducts in rats as measured by immunohistochemistry and high-pressure liquid chromatography.

Le Leu RK, Scherer BL, Mano MT, Winter JM, Lannagan T, Head RJ, Lockett T, Clarke JM.

Nutr Res. 2016 Sep;36(9):982-988. doi: 10.1016/j.nutres.2016.06.006. Epub 2016 Jun 7.

PMID:
27632918
39.

WEE1 inhibition in pancreatic cancer cells is dependent on DNA repair status in a context dependent manner.

Lal S, Zarei M, Chand SN, Dylgjeri E, Mambelli-Lisboa NC, Pishvaian MJ, Yeo CJ, Winter JM, Brody JR.

Sci Rep. 2016 Sep 12;6:33323. doi: 10.1038/srep33323.

40.

Pancreatic Cancer: A Review.

Yabar CS, Winter JM.

Gastroenterol Clin North Am. 2016 Sep;45(3):429-45. doi: 10.1016/j.gtc.2016.04.003. Review.

PMID:
27546841
41.

Increasing resident utilization and recognition of the critical view of safety during laparoscopic cholecystectomy: a pilot study from an academic medical center.

Chen CB, Palazzo F, Doane SM, Winter JM, Lavu H, Chojnacki KA, Rosato EL, Yeo CJ, Pucci MJ.

Surg Endosc. 2017 Apr;31(4):1627-1635. doi: 10.1007/s00464-016-5150-0. Epub 2016 Aug 5.

PMID:
27495348
42.

Identification of a novel metabolic-related mutation (IDH1) in metastatic pancreatic cancer.

Brody JR, Yabar CS, Zarei M, Bender J, Matrisian LM, Rahib L, Heartwell C, Mason K, Yeo CJ, Peiper SC, Jiang W, Varieur K, Madhavan S, Petricoin E 3rd, Fortuna D, Curtis M, Wang ZX, Pishvaian MJ, Winter JM.

Cancer Biol Ther. 2018 Apr 3;19(4):249-253. doi: 10.1080/15384047.2016.1210743. Epub 2018 Mar 6.

PMID:
27466707
43.

ARF6 Is an Actionable Node that Orchestrates Oncogenic GNAQ Signaling in Uveal Melanoma.

Yoo JH, Shi DS, Grossmann AH, Sorensen LK, Tong Z, Mleynek TM, Rogers A, Zhu W, Richards JR, Winter JM, Zhu J, Dunn C, Bajji A, Shenderovich M, Mueller AL, Woodman SE, Harbour JW, Thomas KR, Odelberg SJ, Ostanin K, Li DY.

Cancer Cell. 2016 Jun 13;29(6):889-904. doi: 10.1016/j.ccell.2016.04.015. Epub 2016 Jun 2.

44.

Mutation-specific effects on thin filament length in thin filament myopathy.

Winter JM, Joureau B, Lee EJ, Kiss B, Yuen M, Gupta VA, Pappas CT, Gregorio CC, Stienen GJ, Edvardson S, Wallgren-Pettersson C, Lehtokari VL, Pelin K, Malfatti E, Romero NB, Engelen BG, Voermans NC, Donkervoort S, Bönnemann CG, Clarke NF, Beggs AH, Granzier H, Ottenheijm CA.

Ann Neurol. 2016 Jun;79(6):959-69. doi: 10.1002/ana.24654. Epub 2016 Apr 30.

45.

HuR Contributes to TRAIL Resistance by Restricting Death Receptor 4 Expression in Pancreatic Cancer Cells.

Romeo C, Weber MC, Zarei M, DeCicco D, Chand SN, Lobo AD, Winter JM, Sawicki JA, Sachs JN, Meisner-Kober N, Yeo CJ, Vadigepalli R, Tykocinski ML, Brody JR.

Mol Cancer Res. 2016 Jul;14(7):599-611. doi: 10.1158/1541-7786.MCR-15-0448. Epub 2016 Apr 6.

46.

Combinatorial Generation of Chemical Diversity by Redox Enzymes in Chaetoviridin Biosynthesis.

Sato M, Winter JM, Kishimoto S, Noguchi H, Tang Y, Watanabe K.

Org Lett. 2016 Mar 18;18(6):1446-9. doi: 10.1021/acs.orglett.6b00380. Epub 2016 Mar 9.

47.

The Landscape of Pancreatic Cancer Therapeutic Resistance Mechanisms.

Chand S, O'Hayer K, Blanco FF, Winter JM, Brody JR.

Int J Biol Sci. 2016 Jan 27;12(3):273-82. doi: 10.7150/ijbs.14951. eCollection 2016. Review.

48.

Manipulation of the gut microbiota using resistant starch is associated with protection against colitis-associated colorectal cancer in rats.

Hu Y, Le Leu RK, Christophersen CT, Somashekar R, Conlon MA, Meng XQ, Winter JM, Woodman RJ, McKinnon R, Young GP.

Carcinogenesis. 2016 Apr;37(4):366-375. doi: 10.1093/carcin/bgw019. Epub 2016 Feb 19.

PMID:
26905582
49.

Cholangio-Conundrum: A Case Series of Painless Jaundice.

Johnson AP, Rattigan DA, Pucci MJ, Baliff JP, Winter JM, Yeo CJ, Lavu H.

Case Rep Pancreat Cancer. 2015 Nov 1;1(1):16-21. doi: 10.1089/crpc.2015.29002.apj. eCollection 2015.

50.

Comparison of 10,11-Dehydrocurvularin Polyketide Synthases from Alternaria cinerariae and Aspergillus terreus Highlights Key Structural Motifs.

Cochrane RV, Gao Z, Lambkin GR, Xu W, Winter JM, Marcus SL, Tang Y, Vederas JC.

Chembiochem. 2015 Nov;16(17):2479-83. doi: 10.1002/cbic.201500428. Epub 2015 Oct 23.

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