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Items: 1 to 50 of 883

1.

A solid-phase transfection platform for arrayed CRISPR screens.

Serçin Ö, Reither S, Roidos P, Ballin N, Palikyras S, Baginska A, Rein K, Llamazares M, Halavatyi A, Winter H, Muley T, Jurkowska RZ, Abdollahi A, Zenke FT, Neumann B, Mardin BR.

Mol Syst Biol. 2019 Dec;15(12):e8983. doi: 10.15252/msb.20198983.

2.

Identification of Circulating Genomic and Metabolic Biomarkers in Intrahepatic Cholangiocarcinoma.

Winter H, Kaisaki PJ, Harvey J, Giacopuzzi E, Ferla MP, Pentony MM, Knight SJL, Sharma RA, Taylor JC, McCullagh JSO.

Cancers (Basel). 2019 Nov 28;11(12). pii: E1895. doi: 10.3390/cancers11121895.

3.

Primary pulmonary myxoid sarcoma with an unusual gene fusion between exon 7 of EWSR1 and exon 5 of CREB1.

Koelsche C, Tavernar L, Neumann O, Heußel CP, Eberhardt R, Winter H, Stenzinger A, Mechtersheimer G.

Virchows Arch. 2019 Nov 27. doi: 10.1007/s00428-019-02716-4. [Epub ahead of print]

PMID:
31776646
4.

Population pharmacokinetics, exposure-safety, and immunogenicity of atezolizumab in pediatric and young adult patients with cancer.

Shemesh CS, Chanu P, Jamsen K, Wada R, Rossato G, Donaldson F, Garg A, Winter H, Ruppel J, Wang X, Bruno R, Jin J, Girish S.

J Immunother Cancer. 2019 Nov 21;7(1):314. doi: 10.1186/s40425-019-0791-x.

5.

Bone marrow expands the repertoire of functional T cells targeting tumor-associated antigens in patients with resectable non-small-cell lung cancer.

Safi S, Yamauchi Y, Stamova S, Rathinasamy A, Op den Winkel J, Jünger S, Bucur M, Umansky L, Warth A, Herpel E, Eichhorn M, Winter H, Hoffmann H, Beckhove P.

Oncoimmunology. 2019 Oct 23;8(12):e1671762. doi: 10.1080/2162402X.2019.1671762. eCollection 2019.

6.

The role of ambient sound levels, signal-to-noise ratio, and stimulus pulse rate on behavioural disturbance of seabass in a net pen.

Hubert J, Neo YY, Winter HV, Slabbekoorn H.

Behav Processes. 2020 Jan;170:103992. doi: 10.1016/j.beproc.2019.103992. Epub 2019 Nov 5.

7.

Efficacy and safety of open-label caplacizumab in patients with exacerbations of acquired thrombotic thrombocytopenic purpura in the HERCULES study.

Knoebl P, Cataland S, Peyvandi F, Coppo P, Scully M, Kremer Hovinga JA, Metjian A, de la Rubia J, Pavenski K, Minkue Mi Edou J, De Winter H, Callewaert F.

J Thromb Haemost. 2019 Nov 5:e14679. doi: 10.1111/jth.14679. [Epub ahead of print]

PMID:
31691462
8.

Prognostic relevance of regional lymph-node distribution in patients with N1-positive non-small cell lung cancer: A retrospective single-center analysis.

Eichhorn F, Klotz LV, Muley T, Kobinger S, Winter H, Eichhorn ME.

Lung Cancer. 2019 Dec;138:95-101. doi: 10.1016/j.lungcan.2019.10.018. Epub 2019 Oct 20.

PMID:
31678832
9.

Inverse-micelle synthesis of doxorubicin-loaded alginate/chitosan nanoparticles and in vitro assessment of breast cancer cytotoxicity.

Rosch JG, Winter H, DuRoss AN, Sahay G, Sun C.

Colloid Interface Sci Commun. 2019 Jan;28:69-74. doi: 10.1016/j.colcom.2018.12.002. Epub 2018 Dec 26.

10.

Pulse Delay Time Statistics in a Superradiant Laser with Calcium Atoms.

Laske T, Winter H, Hemmerich A.

Phys Rev Lett. 2019 Sep 6;123(10):103601. doi: 10.1103/PhysRevLett.123.103601.

PMID:
31573286
11.

Alternative dosing regimens for atezolizumab: an example of model-informed drug development in the postmarketing setting.

Morrissey KM, Marchand M, Patel H, Zhang R, Wu B, Phyllis Chan H, Mecke A, Girish S, Jin JY, Winter HR, Bruno R.

Cancer Chemother Pharmacol. 2019 Dec;84(6):1257-1267. doi: 10.1007/s00280-019-03954-8. Epub 2019 Sep 21.

12.

Clinical Significance of SERPINA1 Gene and Its Encoded Alpha1-antitrypsin Protein in NSCLC.

Ercetin E, Richtmann S, Delgado BM, Gomez-Mariano G, Wrenger S, Korenbaum E, Liu B, DeLuca D, Kühnel MP, Jonigk D, Yuskaeva K, Warth A, Muley T, Winter H, Meister M, Welte T, Janciauskiene S, Schneider MA.

Cancers (Basel). 2019 Sep 4;11(9). pii: E1306. doi: 10.3390/cancers11091306.

13.

[Surgical Therapy of Pulmonal Echinococcosis].

Haag JC, Winter H, Eichhorn ME.

Zentralbl Chir. 2019 Sep;144(S 01):S46-S56. doi: 10.1055/a-0851-4199. Epub 2019 Sep 4. German.

PMID:
31484205
14.

Novel Small Molecule-Derived, Highly Selective Substrates for Fibroblast Activation Protein (FAP).

De Decker A, Vliegen G, Van Rompaey D, Peeraer A, Bracke A, Verckist L, Jansen K, Geiss-Friedlander R, Augustyns K, De Winter H, De Meester I, Lambeir AM, Van der Veken P.

ACS Med Chem Lett. 2019 Jul 9;10(8):1173-1179. doi: 10.1021/acsmedchemlett.9b00191. eCollection 2019 Aug 8.

PMID:
31413802
15.

Hepatic Resection Following Selective Internal Radiation Therapy for Colorectal Cancer Metastases in the FOXFIRE Clinical Trial: Clinical Outcomes and Distribution of Microspheres.

Winter H, Rassam J, Virdee PS, Goldin R, Pitcheshwar P, Weaver K, Primrose J, Berry DP, Wasan HS, Sharma RA.

Cancers (Basel). 2019 Aug 12;11(8). pii: E1155. doi: 10.3390/cancers11081155.

16.

Absence of Pharmacokinetic Interactions between the Bruton's Tyrosine Kinase Inhibitor Fenebrutinib and Methotrexate.

Jones NS, Winter H, Katsumoto TR, Florero M, Murray E, Walker H, Singh N, Chinn LW.

J Pharmacol Exp Ther. 2019 Oct;371(1):202-207. doi: 10.1124/jpet.119.257089. Epub 2019 Aug 1.

PMID:
31371481
17.

Spatial and Temporal Heterogeneity of Panel-Based Tumor Mutational Burden in Pulmonary Adenocarcinoma: Separating Biology From Technical Artifacts.

Kazdal D, Endris V, Allgäuer M, Kriegsmann M, Leichsenring J, Volckmar AL, Harms A, Kirchner M, Kriegsmann K, Neumann O, Brandt R, Talla SB, Rempel E, Ploeger C, von Winterfeld M, Christopoulos P, Merino DM, Stewart M, Allen J, Bischoff H, Meister M, Muley T, Herth F, Penzel R, Warth A, Winter H, Fröhling S, Peters S, Swanton C, Thomas M, Schirmacher P, Budczies J, Stenzinger A.

J Thorac Oncol. 2019 Nov;14(11):1935-1947. doi: 10.1016/j.jtho.2019.07.006. Epub 2019 Jul 23.

PMID:
31349062
18.

Efforts towards an On-Target Version of the Groebke-Blackburn-Bienaymé (GBB) Reaction for Discovery of Druglike Urokinase (uPA) Inhibitors.

Gladysz R, Vrijdag J, Van Rompaey D, Lambeir AM, Augustyns K, De Winter H, Van der Veken P.

Chemistry. 2019 Sep 20;25(53):12380-12393. doi: 10.1002/chem.201901917. Epub 2019 Aug 29.

PMID:
31298443
19.

[Expert Recommendation for the Implementation of Hyperthermic Intrathoracic Chemotherapy (HITOC) in Germany].

Ried M, Eichhorn M, Winter H, Grützner U, Lindner M, Hatz RA, Haager B, Passlick B, Galetin T, Lopez-Pastorini A, Stoelben E, Hofmann HS.

Zentralbl Chir. 2019 Jul 10. doi: 10.1055/a-0934-7806. [Epub ahead of print] German.

PMID:
31291667
20.

Pleurectomy/decortication and hyperthermic intrathoracic chemoperfusion using cisplatin and doxorubicin for malignant pleural mesothelioma.

Klotz LV, Lindner M, Eichhorn ME, Grützner U, Koch I, Winter H, Kauke T, Duell T, Hatz RA.

J Thorac Dis. 2019 May;11(5):1963-1972. doi: 10.21037/jtd.2019.04.93.

21.

Additional Intestinal Mucosal Biopsy Sampling for Research Is Safe During Pediatric Endoscopic Procedures.

Moran CJ, Noreck J, Winter HS, Li EX, Biller JA, Israel EJ, Kaplan JL.

Clin Gastroenterol Hepatol. 2019 Jul 4. pii: S1542-3565(19)30731-1. doi: 10.1016/j.cgh.2019.06.040. [Epub ahead of print]

PMID:
31279952
22.

Primary adenoid cystic carcinoma of the trachea: clinical outcome of 38 patients after interdisciplinary treatment in a single institution.

Högerle BA, Lasitschka F, Muley T, Bougatf N, Herfarth K, Adeberg S, Eichhorn M, Debus J, Winter H, Rieken S, Uhl M.

Radiat Oncol. 2019 Jul 4;14(1):117. doi: 10.1186/s13014-019-1323-z.

23.

Prospective analysis of 895 patients on a UK Genomics Review Board.

Moore DA, Kushnir M, Mak G, Winter H, Curiel T, Voskoboynik M, Moschetta M, Rozumna-Martynyuk N, Balbi K, Bennett P, Forster M, Kulkarni A, Haynes D, Swanton C, Arkenau HT.

ESMO Open. 2019 Mar 21;4(2):e000469. doi: 10.1136/esmoopen-2018-000469. eCollection 2019.

24.

[Interventional treatment of tracheopleural and bronchopleural fistulas].

Klotz LV, Eberhardt R, Herth FJF, Winter H.

Chirurg. 2019 Sep;90(9):697-703. doi: 10.1007/s00104-019-0977-2. Review. German.

PMID:
31161248
25.

Performance of Surveillance MR Enterography (MRE) in Asymptomatic Children and Adolescents With Crohn's Disease.

Chu KF, Moran CJ, Wu K, Kaplan JL, Savarino JR, Board T, Israel EJ, Winter HS, Gee MS.

J Magn Reson Imaging. 2019 Dec;50(6):1955-1963. doi: 10.1002/jmri.26811. Epub 2019 May 30.

PMID:
31145502
26.

Multi-omics of the gut microbial ecosystem in inflammatory bowel diseases.

Lloyd-Price J, Arze C, Ananthakrishnan AN, Schirmer M, Avila-Pacheco J, Poon TW, Andrews E, Ajami NJ, Bonham KS, Brislawn CJ, Casero D, Courtney H, Gonzalez A, Graeber TG, Hall AB, Lake K, Landers CJ, Mallick H, Plichta DR, Prasad M, Rahnavard G, Sauk J, Shungin D, Vázquez-Baeza Y, White RA 3rd; IBDMDB Investigators, Braun J, Denson LA, Jansson JK, Knight R, Kugathasan S, McGovern DPB, Petrosino JF, Stappenbeck TS, Winter HS, Clish CB, Franzosa EA, Vlamakis H, Xavier RJ, Huttenhower C.

Nature. 2019 May;569(7758):655-662. doi: 10.1038/s41586-019-1237-9. Epub 2019 May 29.

27.

Long-term Outcomes of Paediatric Patients Admitted With Acute Severe Colitis- A Multicentre Study From the Paediatric IBD Porto Group of ESPGHAN.

Krauthammer A, Tzivinikos C, Assa A, Miele E, Strisciuglio C, Urlep D, Serban ED, Singh A, Winter HS, Russell RK, Hojsak I, Malham M, Navas-López VM, Croft NM, Lee HM, Ledder O, Shamasneh I, Hussey S, Huynh HQ, Wine E, Shah N, Sladek M, de Meij TG, Romano C, Dipasquale V, Lionetti P, Afzal NA, Aloi M, Lee K, Martín-de-Carpi J, Yerushalmy-Feler A, Subramanian S, Weiss B, Shouval DS.

J Crohns Colitis. 2019 Dec 10;13(12):1518-1526. doi: 10.1093/ecco-jcc/jjz092.

PMID:
31120524
28.

Combined Single-Step Procedure for Correction of Silent Sinus Syndrome.

Arnon R, Gluck O, Winter H, Pikkel J, Rubinov A.

Case Rep Ophthalmol. 2019 Mar 19;10(1):95-100. doi: 10.1159/000498964. eCollection 2019 Jan-Apr.

29.

FAM83A and FAM83B as Prognostic Biomarkers and Potential New Therapeutic Targets in NSCLC.

Richtmann S, Wilkens D, Warth A, Lasitschka F, Winter H, Christopoulos P, Herth FJF, Muley T, Meister M, Schneider MA.

Cancers (Basel). 2019 May 11;11(5). pii: E652. doi: 10.3390/cancers11050652.

30.

ClpP Protease, a Promising Antimicrobial Target.

Moreno-Cinos C, Goossens K, Salado IG, Van Der Veken P, De Winter H, Augustyns K.

Int J Mol Sci. 2019 May 7;20(9). pii: E2232. doi: 10.3390/ijms20092232. Review.

31.

Neoadjuvant anti-programmed Death-1 immunotherapy by Pembrolizumab in resectable nodal positive stage II/IIIa non-small-cell lung cancer (NSCLC): the NEOMUN trial.

Eichhorn F, Klotz LV, Bischoff H, Thomas M, Lasitschka F, Winter H, Hoffmann H, Eichhorn ME.

BMC Cancer. 2019 May 2;19(1):413. doi: 10.1186/s12885-019-5624-2.

32.

Quorum sensing between bacterial species on the skin protects against epidermal injury in atopic dermatitis.

Williams MR, Costa SK, Zaramela LS, Khalil S, Todd DA, Winter HL, Sanford JA, O'Neill AM, Liggins MC, Nakatsuji T, Cech NB, Cheung AL, Zengler K, Horswill AR, Gallo RL.

Sci Transl Med. 2019 May 1;11(490). pii: eaat8329. doi: 10.1126/scitranslmed.aat8329.

PMID:
31043573
33.

Mechanistic Links between Non-Coding RNAs and Myeloid Cell Inflammation in Atherosclerosis.

Paloschi V, Winter H, Viola J, Soehnlein O, Maegdefessel L.

Thromb Haemost. 2019 Aug;119(8):1205-1211. doi: 10.1055/s-0039-1687874. Epub 2019 Apr 29.

PMID:
31035303
34.

Clinical pharmacology of caplacizumab for the treatment of patients with acquired thrombotic thrombocytopenic purpura.

Sargentini-Maier ML, De Decker P, Tersteeg C, Canvin J, Callewaert F, De Winter H.

Expert Rev Clin Pharmacol. 2019 Jun;12(6):537-545. doi: 10.1080/17512433.2019.1607293. Epub 2019 Apr 28. Review.

PMID:
30977686
35.

Acetyl Groups in Typha capensis: Fate of Acetates during Organosolv and Ionosolv Pulping.

Audu IG, Brosse N, Winter H, Hoffmann A, Bremer M, Fischer S, Laborie MP.

Polymers (Basel). 2018 Jun 5;10(6). pii: E619. doi: 10.3390/polym10060619.

36.

68Ga-FAPI PET/CT: Tracer Uptake in 28 Different Kinds of Cancer.

Kratochwil C, Flechsig P, Lindner T, Abderrahim L, Altmann A, Mier W, Adeberg S, Rathke H, Röhrich M, Winter H, Plinkert PK, Marme F, Lang M, Kauczor HU, Jäger D, Debus J, Haberkorn U, Giesel FL.

J Nucl Med. 2019 Jun;60(6):801-805. doi: 10.2967/jnumed.119.227967. Epub 2019 Apr 6.

37.

miR-29b Mediates the Chronic Inflammatory Response in Radiotherapy-Induced Vascular Disease.

Eken SM, Christersdottir T, Winski G, Sangsuwan T, Jin H, Chernogubova E, Pirault J, Sun C, Simon N, Winter H, Backlund A, Haghdoost S, Hansson GK, Halle M, Maegdefessel L.

JACC Basic Transl Sci. 2019 Feb 25;4(1):72-82. doi: 10.1016/j.jacbts.2018.10.006. eCollection 2019 Feb.

38.

Agreement of CK5/6, p40, and p63 immunoreactivity in non-small cell lung cancer.

Kriegsmann K, Cremer M, Zgorzelski C, Harms A, Muley T, Winter H, Kazdal D, Warth A, Kriegsmann M.

Pathology. 2019 Apr;51(3):240-245. doi: 10.1016/j.pathol.2018.11.009. Epub 2019 Feb 21.

PMID:
30798982
39.

Measurement of Microvascular Function in Pediatric Inflammatory Bowel Disease.

Morhardt TL, Winter HS.

J Pediatr Gastroenterol Nutr. 2019 May;68(5):608-609. doi: 10.1097/MPG.0000000000002299. No abstract available.

PMID:
30724795
40.

Combined targeted DNA and RNA sequencing of advanced NSCLC in routine molecular diagnostics: Analysis of the first 3,000 Heidelberg cases.

Volckmar AL, Leichsenring J, Kirchner M, Christopoulos P, Neumann O, Budczies J, Morais de Oliveira CM, Rempel E, Buchhalter I, Brandt R, Allgäuer M, Talla SB, von Winterfeld M, Herpel E, Goeppert B, Lier A, Winter H, Brummer T, Fröhling S, Faehling M, Fischer JR, Heußel CP, Herth F, Lasitschka F, Schirmacher P, Thomas M, Endris V, Penzel R, Stenzinger A.

Int J Cancer. 2019 Aug 1;145(3):649-661. doi: 10.1002/ijc.32133. Epub 2019 Feb 19.

PMID:
30653256
41.

Caplacizumab Treatment for Acquired Thrombotic Thrombocytopenic Purpura.

Scully M, Cataland SR, Peyvandi F, Coppo P, Knöbl P, Kremer Hovinga JA, Metjian A, de la Rubia J, Pavenski K, Callewaert F, Biswas D, De Winter H, Zeldin RK; HERCULES Investigators.

N Engl J Med. 2019 Jan 24;380(4):335-346. doi: 10.1056/NEJMoa1806311. Epub 2019 Jan 9.

42.

Pathways regulating the expression of the immunomodulatory protein glycodelin in non‑small cell lung cancer.

Weber R, Meister M, Muley T, Thomas M, Sültmann H, Warth A, Winter H, Herth FJF, Schneider MA.

Int J Oncol. 2019 Feb;54(2):515-526. doi: 10.3892/ijo.2018.4654. Epub 2018 Dec 5.

43.

Subclonal evolution of pulmonary adenocarcinomas delineated by spatially distributed somatic mitochondrial mutations.

Kazdal D, Harms A, Endris V, Penzel R, Oliveira C, Kriegsmann M, Longuespée R, Winter H, Schneider MA, Muley T, Pfarr N, Weichert W, Stenzinger A, Warth A.

Lung Cancer. 2018 Dec;126:80-88. doi: 10.1016/j.lungcan.2018.10.024. Epub 2018 Oct 29.

PMID:
30527196
44.

Microbiota profile in new-onset pediatric Crohn's disease: data from a non-Western population.

El Mouzan MI, Winter HS, Assiri AA, Korolev KS, Al Sarkhy AA, Dowd SE, Al Mofarreh MA, Menon R.

Gut Pathog. 2018 Nov 29;10:49. doi: 10.1186/s13099-018-0276-3. eCollection 2018.

45.

Glycodelin as a Serum and Tissue Biomarker for Metastatic and Advanced NSCLC.

Schneider MA, Muley T, Weber R, Wessels S, Thomas M, Herth FJF, Kahn NC, Eberhardt R, Winter H, Heussel G, Warth A, Herold-Mende C, Meister M.

Cancers (Basel). 2018 Dec 4;10(12). pii: E486. doi: 10.3390/cancers10120486.

46.

Measurement of tumor mutational burden (TMB) in routine molecular diagnostics: in silico and real-life analysis of three larger gene panels.

Endris V, Buchhalter I, Allgäuer M, Rempel E, Lier A, Volckmar AL, Kirchner M, von Winterfeld M, Leichsenring J, Neumann O, Penzel R, Weichert W, Glimm H, Fröhling S, Winter H, Herth F, Thomas M, Schirmacher P, Budczies J, Stenzinger A.

Int J Cancer. 2019 May 1;144(9):2303-2312. doi: 10.1002/ijc.32002. Epub 2019 Feb 4.

PMID:
30446996
47.

Insulinoma-associated Protein 1 (INSM1) in Thoracic Tumors is Less Sensitive but More Specific Compared With Synaptophysin, Chromogranin A, and CD56.

Kriegsmann K, Zgorzelski C, Kazdal D, Cremer M, Muley T, Winter H, Longuespée R, Kriegsmann J, Warth A, Kriegsmann M.

Appl Immunohistochem Mol Morphol. 2018 Oct 24. doi: 10.1097/PAI.0000000000000715. [Epub ahead of print]

PMID:
30358615
48.

Fungal dysbiosis predicts the diagnosis of pediatric Crohn's disease.

El Mouzan MI, Korolev KS, Al Mofarreh MA, Menon R, Winter HS, Al Sarkhy AA, Dowd SE, Al Barrag AM, Assiri AA.

World J Gastroenterol. 2018 Oct 21;24(39):4510-4516. doi: 10.3748/wjg.v24.i39.4510.

49.

Discovery of Novel, Drug-Like Ferroptosis Inhibitors with in Vivo Efficacy.

Devisscher L, Van Coillie S, Hofmans S, Van Rompaey D, Goossens K, Meul E, Maes L, De Winter H, Van Der Veken P, Vandenabeele P, Berghe TV, Augustyns K.

J Med Chem. 2018 Nov 21;61(22):10126-10140. doi: 10.1021/acs.jmedchem.8b01299. Epub 2018 Nov 6.

PMID:
30354101
50.

Global DNA methylation reflects spatial heterogeneity and molecular evolution of lung adenocarcinomas.

Dietz S, Lifshitz A, Kazdal D, Harms A, Endris V, Winter H, Stenzinger A, Warth A, Sill M, Tanay A, Sültmann H.

Int J Cancer. 2019 Mar 1;144(5):1061-1072. doi: 10.1002/ijc.31939. Epub 2018 Dec 3.

PMID:
30350867

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