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Items: 6

1.

23814, an Inhibitory Antibody of Ligand-Mediated Notch1 Activation, Modulates Angiogenesis and Inhibits Tumor Growth without Gastrointestinal Toxicity.

Proia T, Jiang F, Bell A, Nicoletti R, Kong L, Kreuter K, Poling L, Winston WM, Flaherty M, Weiler S, Perino S, O'Hagan R, Lin J, Gyuris J, Okamura H.

Mol Cancer Ther. 2015 Aug;14(8):1858-67. doi: 10.1158/1535-7163.MCT-14-1104. Epub 2015 May 20.

2.

Neuregulin 1 expression is a predictive biomarker for response to AV-203, an ERBB3 inhibitory antibody, in human tumor models.

Meetze K, Vincent S, Tyler S, Mazsa EK, Delpero AR, Bottega S, McIntosh D, Nicoletti R, Winston WM, Weiler S, Feng B, Gyuris J, Weng Z.

Clin Cancer Res. 2015 Mar 1;21(5):1106-14. doi: 10.1158/1078-0432.CCR-14-2407. Epub 2014 Dec 26.

3.

GP369, an FGFR2-IIIb-specific antibody, exhibits potent antitumor activity against human cancers driven by activated FGFR2 signaling.

Bai A, Meetze K, Vo NY, Kollipara S, Mazsa EK, Winston WM, Weiler S, Poling LL, Chen T, Ismail NS, Jiang J, Lerner L, Gyuris J, Weng Z.

Cancer Res. 2010 Oct 1;70(19):7630-9. doi: 10.1158/0008-5472.CAN-10-1489. Epub 2010 Aug 13.

4.

Caenorhabditis elegans SID-2 is required for environmental RNA interference.

Winston WM, Sutherlin M, Wright AJ, Feinberg EH, Hunter CP.

Proc Natl Acad Sci U S A. 2007 Jun 19;104(25):10565-70. Epub 2007 Jun 11.

5.

Systemic RNAi in Caenorhabditis elegans.

Hunter CP, Winston WM, Molodowitch C, Feinberg EH, Shih J, Sutherlin M, Wright AJ, Fitzgerald MC.

Cold Spring Harb Symp Quant Biol. 2006;71:95-100. Review.

PMID:
17381285
6.

Systemic RNAi in C. elegans requires the putative transmembrane protein SID-1.

Winston WM, Molodowitch C, Hunter CP.

Science. 2002 Mar 29;295(5564):2456-9. Epub 2002 Feb 7.

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