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Items: 1 to 50 of 92

1.

Exposure to uncertainty mediates the effects of traumatic brain injury on probabilistic decision-making in rats.

Vonder Haar C, O'Hearn CM, Winstanley CA.

Brain Inj. 2019 Sep 18:1-9. doi: 10.1080/02699052.2019.1669073. [Epub ahead of print]

PMID:
31532706
2.

Relative insensitivity to time-out punishments induced by win-paired cues in a rat gambling task.

Langdon AJ, Hathaway BA, Zorowitz S, Harris CBW, Winstanley CA.

Psychopharmacology (Berl). 2019 Aug;236(8):2543-2556. doi: 10.1007/s00213-019-05308-x. Epub 2019 Jun 29.

PMID:
31256220
3.

Risk taking and impulsive behaviour: fundamental discoveries, theoretical perspectives and clinical implications.

Isles AR, Winstanley CA, Humby T.

Philos Trans R Soc Lond B Biol Sci. 2019 Feb 18;374(1766):20180128. doi: 10.1098/rstb.2018.0128.

4.

Repetitive closed-head impact model of engineered rotational acceleration (CHIMERA) injury in rats increases impulsivity, decreases dopaminergic innervation in the olfactory tubercle and generates white matter inflammation, tau phosphorylation and degeneration.

Vonder Haar C, Martens KM, Bashir A, McInnes KA, Cheng WH, Cheung H, Stukas S, Barron C, Ladner T, Welch KA, Cripton PA, Winstanley CA, Wellington CL.

Exp Neurol. 2019 Jul;317:87-99. doi: 10.1016/j.expneurol.2019.02.012. Epub 2019 Feb 26.

PMID:
30822421
5.

Increased motor impulsivity in a rat gambling task during chronic ropinirole treatment: potentiation by win-paired audiovisual cues.

Tremblay M, Barrus MM, Cocker PJ, Baunez C, Winstanley CA.

Psychopharmacology (Berl). 2019 Jun;236(6):1901-1915. doi: 10.1007/s00213-019-5173-z. Epub 2019 Jan 31.

PMID:
30706098
6.

Prior Exposure to Salient Win-Paired Cues in a Rat Gambling Task Increases Sensitivity to Cocaine Self-Administration and Suppresses Dopamine Efflux in Nucleus Accumbens: Support for the Reward Deficiency Hypothesis of Addiction.

Ferland JN, Hynes TJ, Hounjet CD, Lindenbach D, Vonder Haar C, Adams WK, Phillips AG, Winstanley CA.

J Neurosci. 2019 Mar 6;39(10):1842-1854. doi: 10.1523/JNEUROSCI.3477-17.2018. Epub 2019 Jan 9.

7.

Investigating the influence of 'losses disguised as wins' on decision making and motivation in rats.

Ferland JN, Adams WK, Murch S, Wei L, Clark L, Winstanley CA.

Behav Pharmacol. 2018 Dec;29(8):732-744. doi: 10.1097/FBP.0000000000000455.

PMID:
30376458
8.

Win-Concurrent Sensory Cues Can Promote Riskier Choice.

Cherkasova MV, Clark L, Barton JJS, Schulzer M, Shafiee M, Kingstone A, Stoessl AJ, Winstanley CA.

J Neurosci. 2018 Nov 28;38(48):10362-10370. doi: 10.1523/JNEUROSCI.1171-18.2018. Epub 2018 Oct 29.

9.

Cocaine self-administration is increased after frontal traumatic brain injury and associated with neuroinflammation.

Vonder Haar C, Ferland JN, Kaur S, Riparip LK, Rosi S, Winstanley CA.

Eur J Neurosci. 2019 Aug;50(3):2134-2145. doi: 10.1111/ejn.14123. Epub 2018 Oct 10.

PMID:
30118561
10.

The β-adrenoceptor blocker propranolol ameliorates compulsive-like gambling behaviour in a rodent slot machine task: implications for iatrogenic gambling disorder.

Cocker PJ, Lin MY, Tremblay M, Kaur S, Winstanley CA.

Eur J Neurosci. 2019 Aug;50(3):2401-2414. doi: 10.1111/ejn.14070. Epub 2018 Aug 3.

PMID:
30019362
11.

The putative lithium-mimetic ebselen reduces impulsivity in rodent models.

Barkus C, Ferland JN, Adams WK, Churchill GC, Cowen PJ, Bannerman DM, Rogers RD, Winstanley CA, Sharp T.

J Psychopharmacol. 2018 Sep;32(9):1018-1026. doi: 10.1177/0269881118784876. Epub 2018 Jul 10.

PMID:
29986609
12.

Examination of the effects of cannabinoid ligands on decision making in a rat gambling task.

Ferland JN, Carr MR, Lee AM, Hoogeland ME, Winstanley CA, Pattij T.

Pharmacol Biochem Behav. 2018 Jul;170:87-97. doi: 10.1016/j.pbb.2018.05.012. Epub 2018 May 19.

13.

Dissociable contributions of dorsal and ventral striatal regions on a rodent cost/benefit decision-making task requiring cognitive effort.

Silveira MM, Tremblay M, Winstanley CA.

Neuropharmacology. 2018 Jul 15;137:322-331. doi: 10.1016/j.neuropharm.2018.04.025. Epub 2018 Apr 24.

PMID:
29778947
14.

Enhanced amphetamine-induced motor impulsivity and mild attentional impairment in the leptin-deficient rat model of obesity.

Adams WK, D'souza AM, Sussman JL, Kaur S, Kieffer TJ, Winstanley CA.

Physiol Behav. 2018 Aug 1;192:134-144. doi: 10.1016/j.physbeh.2018.03.027. Epub 2018 Mar 27.

PMID:
29601831
15.

Dietary influences on cognition.

Reichelt AC, Stoeckel LE, Reagan LP, Winstanley CA, Page KA.

Physiol Behav. 2018 Aug 1;192:118-126. doi: 10.1016/j.physbeh.2018.02.052. Epub 2018 Mar 1.

16.

Deep-Brain Stimulation of the Subthalamic Nucleus Selectively Decreases Risky Choice in Risk-Preferring Rats.

Adams WK, Vonder Haar C, Tremblay M, Cocker PJ, Silveira MM, Kaur S, Baunez C, Winstanley CA.

eNeuro. 2017 Aug 7;4(4). pii: ENEURO.0094-17.2017. doi: 10.1523/ENEURO.0094-17.2017. eCollection 2017 Jul-Aug.

17.

Pharmacological evidence that 5-HT2C receptor blockade selectively improves decision making when rewards are paired with audiovisual cues in a rat gambling task.

Adams WK, Barkus C, Ferland JN, Sharp T, Winstanley CA.

Psychopharmacology (Berl). 2017 Oct;234(20):3091-3104. doi: 10.1007/s00213-017-4696-4. Epub 2017 Jul 21.

PMID:
28733811
18.

Frontal Traumatic Brain Injury Increases Impulsive Decision Making in Rats: A Potential Role for the Inflammatory Cytokine Interleukin-12.

Vonder Haar C, Martens KM, Riparip LK, Rosi S, Wellington CL, Winstanley CA.

J Neurotrauma. 2017 Oct 1;34(19):2790-2800. doi: 10.1089/neu.2016.4813. Epub 2017 May 24.

19.

Dissociable effects of systemic and orbitofrontal administration of adrenoceptor antagonists on yohimbine-induced motor impulsivity.

Adams WK, Barrus MM, Zeeb FD, Cocker PJ, Benoit J, Winstanley CA.

Behav Brain Res. 2017 Jun 15;328:19-27. doi: 10.1016/j.bbr.2017.03.034. Epub 2017 Mar 23.

PMID:
28344096
20.

Δ9-Tetrahydrocannabinol decreases willingness to exert cognitive effort in male rats.

Silveira MM, Adams WK, Morena M, Hill MN, Winstanley CA.

J Psychiatry Neurosci. 2017 Mar;42(2):131-138.

22.

Research Domain Criteria versus DSM V: How does this debate affect attempts to model corticostriatal dysfunction in animals?

Young JW, Winstanley CA, Brady AM, Hall FS.

Neurosci Biobehav Rev. 2017 May;76(Pt B):301-316. doi: 10.1016/j.neubiorev.2016.10.029. Epub 2016 Nov 5. Review.

PMID:
27826070
23.

Minor Functional Deficits in Basic Response Patterns for Reinforcement after Frontal Traumatic Brain Injury in Rats.

Vonder Haar C, Winstanley CA.

J Neurotrauma. 2016 Oct 15;33(20):1892-1900. Epub 2016 Mar 29.

PMID:
26756392
24.

Chronic administration of the dopamine D2/3 agonist ropinirole invigorates performance of a rodent slot machine task, potentially indicative of less distractible or compulsive-like gambling behaviour.

Cocker PJ, Tremblay M, Kaur S, Winstanley CA.

Psychopharmacology (Berl). 2017 Jan;234(1):137-153. doi: 10.1007/s00213-016-4447-y. Epub 2016 Oct 6.

PMID:
27714426
25.

Δ9-Tetrahydrocannabinol decreases willingness to exert cognitive effort in male rats.

Silveira MM, Adams WK, Morena M, Hill MN, Winstanley CA.

J Psychiatry Neurosci. 2016 Aug 23;41(6):150363. doi: 10.1503/jpn.150363. [Epub ahead of print]

26.

Frontal Traumatic Brain Injury in Rats Causes Long-Lasting Impairments in Impulse Control That Are Differentially Sensitive to Pharmacotherapeutics and Associated with Chronic Neuroinflammation.

Vonder Haar C, Lam FC, Adams WK, Riparip LK, Kaur S, Muthukrishna M, Rosi S, Winstanley CA.

ACS Chem Neurosci. 2016 Nov 16;7(11):1531-1542. Epub 2016 Aug 30.

PMID:
27525447
27.

Anticonvulsant medications attenuate amphetamine-induced deficits in behavioral inhibition but not decision making under risk on a rat gambling task.

Tremblay M, Winstanley CA.

Behav Brain Res. 2016 Nov 1;314:143-51. doi: 10.1016/j.bbr.2016.08.016. Epub 2016 Aug 8.

PMID:
27515288
28.

Chronic D2/3 agonist ropinirole treatment increases preference for uncertainty in rats regardless of baseline choice patterns.

Tremblay M, Silveira MM, Kaur S, Hosking JG, Adams WK, Baunez C, Winstanley CA.

Eur J Neurosci. 2017 Jan;45(1):159-166. doi: 10.1111/ejn.13332. Epub 2016 Aug 11.

PMID:
27422144
29.

Translational Models of Gambling-Related Decision-Making.

Winstanley CA, Clark L.

Curr Top Behav Neurosci. 2016;28:93-120. doi: 10.1007/7854_2015_5014. Review.

PMID:
27418069
30.

The agranular and granular insula differentially contribute to gambling-like behavior on a rat slot machine task: effects of inactivation and local infusion of a dopamine D4 agonist on reward expectancy.

Cocker PJ, Lin MY, Barrus MM, Le Foll B, Winstanley CA.

Psychopharmacology (Berl). 2016 Sep;233(17):3135-47. doi: 10.1007/s00213-016-4355-1. Epub 2016 Jul 14.

PMID:
27417550
31.

Elucidating the role of D4 receptors in mediating attributions of salience to incentive stimuli on Pavlovian conditioned approach and conditioned reinforcement paradigms.

Cocker PJ, Vonder Haar C, Winstanley CA.

Behav Brain Res. 2016 Oct 1;312:55-63. doi: 10.1016/j.bbr.2016.06.007. Epub 2016 Jun 6.

PMID:
27275521
32.

Risk-preferring rats make worse decisions and show increased incubation of craving after cocaine self-administration.

Ferland JN, Winstanley CA.

Addict Biol. 2017 Jul;22(4):991-1001. doi: 10.1111/adb.12388. Epub 2016 Mar 22.

PMID:
27002211
33.

Inactivation of the orbitofrontal cortex reduces irrational choice on a rodent Betting Task.

Barrus MM, Hosking JG, Cocker PJ, Winstanley CA.

Neuroscience. 2017 Mar 14;345:38-48. doi: 10.1016/j.neuroscience.2016.02.028. Epub 2016 Feb 18.

PMID:
26912278
34.

Dopamine D3 Receptors Modulate the Ability of Win-Paired Cues to Increase Risky Choice in a Rat Gambling Task.

Barrus MM, Winstanley CA.

J Neurosci. 2016 Jan 20;36(3):785-94. doi: 10.1523/JNEUROSCI.2225-15.2016.

35.

Activation of dopamine D4 receptors within the anterior cingulate cortex enhances the erroneous expectation of reward on a rat slot machine task.

Cocker PJ, Hosking JG, Murch WS, Clark L, Winstanley CA.

Neuropharmacology. 2016 Jun;105:186-195. doi: 10.1016/j.neuropharm.2016.01.019. Epub 2016 Jan 15.

PMID:
26775821
36.

Chronic atomoxetine treatment during adolescence does not influence decision-making on a rodent gambling task, but does modulate amphetamine's effect on impulsive action in adulthood.

Silveira MM, Murch WS, Clark L, Winstanley CA.

Behav Pharmacol. 2016 Jun;27(4):350-63. doi: 10.1097/FBP.0000000000000203.

PMID:
26650252
37.

Skewed by Cues? The Motivational Role of Audiovisual Stimuli in Modelling Substance Use and Gambling Disorders.

Barrus MM, Cherkasova M, Winstanley CA.

Curr Top Behav Neurosci. 2016;27:507-29. doi: 10.1007/7854_2015_393. Review.

PMID:
26531068
38.

Long-term, calorie-restricted intake of a high-fat diet in rats reduces impulse control and ventral striatal D2 receptor signalling - two markers of addiction vulnerability.

Adams WK, Sussman JL, Kaur S, D'souza AM, Kieffer TJ, Winstanley CA.

Eur J Neurosci. 2015 Dec;42(12):3095-104. doi: 10.1111/ejn.13117.

PMID:
26527415
39.

Inactivation of the prelimbic or infralimbic cortex impairs decision-making in the rat gambling task.

Zeeb FD, Baarendse PJ, Vanderschuren LJ, Winstanley CA.

Psychopharmacology (Berl). 2015 Dec;232(24):4481-91. doi: 10.1007/s00213-015-4075-y. Epub 2015 Sep 21.

PMID:
26387517
40.

The Impact of Selective Dopamine D2, D3 and D4 Ligands on the Rat Gambling Task.

Di Ciano P, Pushparaj A, Kim A, Hatch J, Masood T, Ramzi A, Khaled MA, Boileau I, Winstanley CA, Le Foll B.

PLoS One. 2015 Sep 9;10(9):e0136267. doi: 10.1371/journal.pone.0136267. eCollection 2015.

41.

Differential Involvement of the Agranular vs Granular Insular Cortex in the Acquisition and Performance of Choice Behavior in a Rodent Gambling Task.

Pushparaj A, Kim AS, Musiol M, Zangen A, Daskalakis ZJ, Zack M, Winstanley CA, Le Foll B.

Neuropsychopharmacology. 2015 Nov;40(12):2832-42. doi: 10.1038/npp.2015.133. Epub 2015 May 8.

42.

Choice impulsivity: Definitions, measurement issues, and clinical implications.

Hamilton KR, Mitchell MR, Wing VC, Balodis IM, Bickel WK, Fillmore M, Lane SD, Lejuez CW, Littlefield AK, Luijten M, Mathias CW, Mitchell SH, Napier TC, Reynolds B, Schütz CG, Setlow B, Sher KJ, Swann AC, Tedford SE, White MJ, Winstanley CA, Yi R, Potenza MN, Moeller FG.

Personal Disord. 2015 Apr;6(2):182-98. doi: 10.1037/per0000099. Review.

43.

Disadvantageous decision-making on a rodent gambling task is associated with increased motor impulsivity in a population of male rats.

Barrus MM, Hosking JG, Zeeb FD, Tremblay M, Winstanley CA.

J Psychiatry Neurosci. 2015 Mar;40(2):108-17.

44.

Prefrontal Cortical Inactivations Decrease Willingness to Expend Cognitive Effort on a Rodent Cost/Benefit Decision-Making Task.

Hosking JG, Cocker PJ, Winstanley CA.

Cereb Cortex. 2016 Apr;26(4):1529-38. doi: 10.1093/cercor/bhu321. Epub 2015 Jan 16.

45.

Scopolamine and amphetamine produce similar decision-making deficits on a rat gambling task via independent pathways.

Silveira MM, Malcolm E, Shoaib M, Winstanley CA.

Behav Brain Res. 2015 Mar 15;281:86-95. doi: 10.1016/j.bbr.2014.12.029. Epub 2014 Dec 18.

PMID:
25529186
46.

Irrational beliefs, biases and gambling: exploring the role of animal models in elucidating vulnerabilities for the development of pathological gambling.

Cocker PJ, Winstanley CA.

Behav Brain Res. 2015 Feb 15;279:259-73. doi: 10.1016/j.bbr.2014.10.043. Epub 2014 Nov 4. Review.

PMID:
25446745
47.
48.

Dopamine antagonism decreases willingness to expend physical, but not cognitive, effort: a comparison of two rodent cost/benefit decision-making tasks.

Hosking JG, Floresco SB, Winstanley CA.

Neuropsychopharmacology. 2015 Mar;40(4):1005-15. doi: 10.1038/npp.2014.285. Epub 2014 Oct 20.

49.

Greater sensitivity to novelty in rats is associated with increased motor impulsivity following repeated exposure to a stimulating environment: implications for the etiology of impulse control deficits.

Ferland JM, Zeeb FD, Yu K, Kaur S, Taves MD, Winstanley CA.

Eur J Neurosci. 2014 Dec;40(12):3746-56. doi: 10.1111/ejn.12748. Epub 2014 Oct 12.

PMID:
25308904
50.

Prenatal alcohol exposure and adolescent stress - unmasking persistent attentional deficits in rats.

Comeau WL, Winstanley CA, Weinberg J.

Eur J Neurosci. 2014 Oct;40(7):3078-95. doi: 10.1111/ejn.12671. Epub 2014 Jul 25.

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