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Items: 37


REM sleep's unique associations with corticosterone regulation, apoptotic pathways, and behavior in chronic stress in mice.

Nollet M, Hicks H, McCarthy AP, Wu H, Möller-Levet CS, Laing EE, Malki K, Lawless N, Wafford KA, Dijk DJ, Winsky-Sommerer R.

Proc Natl Acad Sci U S A. 2019 Feb 12;116(7):2733-2742. doi: 10.1073/pnas.1816456116. Epub 2019 Jan 25.


Disturbances of sleep quality, timing and structure and their relationship with other neuropsychiatric symptoms in Alzheimer's disease and schizophrenia: Insights from studies in patient populations and animal models.

Winsky-Sommerer R, de Oliveira P, Loomis S, Wafford K, Dijk DJ, Gilmour G.

Neurosci Biobehav Rev. 2019 Feb;97:112-137. doi: 10.1016/j.neubiorev.2018.09.027. Epub 2018 Oct 9. Review.


Obstructive sleep apnoea and Alzheimer's disease: In search of shared pathomechanisms.

Polsek D, Gildeh N, Cash D, Winsky-Sommerer R, Williams SCR, Turkheimer F, Leschziner GD, Morrell MJ, Rosenzweig I.

Neurosci Biobehav Rev. 2018 Mar;86:142-149. doi: 10.1016/j.neubiorev.2017.12.004. Epub 2017 Dec 7. Review.


Enhanced sleep reverses memory deficits and underlying pathology in Drosophila models of Alzheimer's disease.

Dissel S, Klose M, Donlea J, Cao L, English D, Winsky-Sommerer R, van Swinderen B, Shaw PJ.

Neurobiol Sleep Circadian Rhythms. 2017 Jan;2:15-26. doi: 10.1016/j.nbscr.2016.09.001. Epub 2016 Sep 28.


Modulation of Adult Hippocampal Neurogenesis by Sleep: Impact on Mental Health.

Navarro-Sanchis C, Brock O, Winsky-Sommerer R, Thuret S.

Front Neural Circuits. 2017 Oct 12;11:74. doi: 10.3389/fncir.2017.00074. eCollection 2017. Review.


Neuroscience: Sleepy and dreamless mutant mice.

Dijk DJ, Winsky-Sommerer R.

Nature. 2016 Nov 17;539(7629):364-365. doi: 10.1038/nature20471. Epub 2016 Nov 2. No abstract available.


Modelling maintenance of wakefulness in rats: comparing potential non-invasive sleep-restriction methods and their effects on sleep and attentional performance.

Mccarthy A, Loomis S, Eastwood B, Wafford KA, Winsky-Sommerer R, Gilmour G.

J Sleep Res. 2017 Apr;26(2):179-187. doi: 10.1111/jsr.12464. Epub 2016 Oct 14.


Emotional Impairment and Persistent Upregulation of mGlu5 Receptor following Morphine Abstinence: Implications of an mGlu5-MOPr Interaction.

Zanos P, Georgiou P, Gonzalez LR, Hourani S, Chen Y, Kitchen I, Kieffer BL, Winsky-Sommerer R, Bailey A.

Int J Neuropsychopharmacol. 2016 Jul 5;19(7). pii: pyw011. doi: 10.1093/ijnp/pyw011. Print 2016 Jul.


Region-specific up-regulation of oxytocin receptor binding in the brain of mice following chronic nicotine administration.

Zanos P, Georgiou P, Metaxas A, Kitchen I, Winsky-Sommerer R, Bailey A.

Neurosci Lett. 2015 Jul 23;600:33-7. doi: 10.1016/j.neulet.2015.05.054. Epub 2015 May 30.


A critical role of striatal A2A R-mGlu5 R interactions in modulating the psychomotor and drug-seeking effects of methamphetamine.

Wright SR, Zanos P, Georgiou P, Yoo JH, Ledent C, Hourani SM, Kitchen I, Winsky-Sommerer R, Bailey A.

Addict Biol. 2016 Jul;21(4):811-25. doi: 10.1111/adb.12259. Epub 2015 May 15.


Sleep restores behavioral plasticity to Drosophila mutants.

Dissel S, Angadi V, Kirszenblat L, Suzuki Y, Donlea J, Klose M, Koch Z, English D, Winsky-Sommerer R, van Swinderen B, Shaw PJ.

Curr Biol. 2015 May 18;25(10):1270-81. doi: 10.1016/j.cub.2015.03.027. Epub 2015 Apr 23.


A human sleep homeostasis phenotype in mice expressing a primate-specific PER3 variable-number tandem-repeat coding-region polymorphism.

Hasan S, van der Veen DR, Winsky-Sommerer R, Hogben A, Laing EE, Koentgen F, Dijk DJ, Archer SN.

FASEB J. 2014 Jun;28(6):2441-54. doi: 10.1096/fj.13-240135. Epub 2014 Feb 27.


The oxytocin analogue carbetocin prevents emotional impairment and stress-induced reinstatement of opioid-seeking in morphine-abstinent mice.

Zanos P, Georgiou P, Wright SR, Hourani SM, Kitchen I, Winsky-Sommerer R, Bailey A.

Neuropsychopharmacology. 2014 Mar;39(4):855-65. doi: 10.1038/npp.2013.285. Epub 2013 Oct 15.


Chronic methamphetamine treatment induces oxytocin receptor up-regulation in the amygdala and hypothalamus via an adenosine A2A receptor-independent mechanism.

Zanos P, Wright SR, Georgiou P, Yoo JH, Ledent C, Hourani SM, Kitchen I, Winsky-Sommerer R, Bailey A.

Pharmacol Biochem Behav. 2014 Apr;119:72-9. doi: 10.1016/j.pbb.2013.05.009. Epub 2013 May 13.


Differential effects of a dual orexin receptor antagonist (SB-649868) and zolpidem on sleep initiation and consolidation, SWS, REM sleep, and EEG power spectra in a model of situational insomnia.

Bettica P, Squassante L, Groeger JA, Gennery B, Winsky-Sommerer R, Dijk DJ.

Neuropsychopharmacology. 2012 Apr;37(5):1224-33. doi: 10.1038/npp.2011.310. Epub 2012 Jan 11.


Altered sleep and behavioral activity phenotypes in PER3-deficient mice.

Hasan S, van der Veen DR, Winsky-Sommerer R, Dijk DJ, Archer SN.

Am J Physiol Regul Integr Comp Physiol. 2011 Dec;301(6):R1821-30. doi: 10.1152/ajpregu.00260.2011. Epub 2011 Sep 28.


Arousal effect of caffeine depends on adenosine A2A receptors in the shell of the nucleus accumbens.

Lazarus M, Shen HY, Cherasse Y, Qu WM, Huang ZL, Bass CE, Winsky-Sommerer R, Semba K, Fredholm BB, Boison D, Hayaishi O, Urade Y, Chen JF.

J Neurosci. 2011 Jul 6;31(27):10067-75. doi: 10.1523/JNEUROSCI.6730-10.2011.


Manipulation of adenosine kinase affects sleep regulation in mice.

Palchykova S, Winsky-Sommerer R, Shen HY, Boison D, Gerling A, Tobler I.

J Neurosci. 2010 Sep 29;30(39):13157-65. doi: 10.1523/JNEUROSCI.1359-10.2010.


Role of GABAA receptors in the physiology and pharmacology of sleep.

Winsky-Sommerer R.

Eur J Neurosci. 2009 May;29(9):1779-94. doi: 10.1111/j.1460-9568.2009.06716.x. Epub 2009 Apr 27. Review.


Sleep deprivation in the dark period does not impair memory in OF1 mice.

Palchykova S, Winsky-Sommerer R, Tobler I.

Chronobiol Int. 2009 May;26(4):682-96. doi: 10.1080/07420520902926025.


Normal sleep homeostasis and lack of epilepsy phenotype in GABA A receptor alpha3 subunit-knockout mice.

Winsky-Sommerer R, Knapman A, Fedele DE, Schofield CM, Vyazovskiy VV, Rudolph U, Huguenard JR, Fritschy JM, Tobler I.

Neuroscience. 2008 Jun 23;154(2):595-605. doi: 10.1016/j.neuroscience.2008.03.081. Epub 2008 Apr 11.


Alteration of behavior in mice by muscimol is associated with regional electroencephalogram synchronization.

Vyazovskiy VV, Tobler I, Winsky-Sommerer R.

Neuroscience. 2007 Jul 13;147(3):833-41. Epub 2007 Jun 13.


The EEG effects of THIP (Gaboxadol) on sleep and waking are mediated by the GABA(A)delta-subunit-containing receptors.

Winsky-Sommerer R, Vyazovskiy VV, Homanics GE, Tobler I.

Eur J Neurosci. 2007 Mar;25(6):1893-9. Epub 2007 Apr 4.


Transgenic mice with a reduced core body temperature have an increased life span.

Conti B, Sanchez-Alavez M, Winsky-Sommerer R, Morale MC, Lucero J, Brownell S, Fabre V, Huitron-Resendiz S, Henriksen S, Zorrilla EP, de Lecea L, Bartfai T.

Science. 2006 Nov 3;314(5800):825-8.


Sleep deprivation impairs object recognition in mice.

Palchykova S, Winsky-Sommerer R, Meerlo P, Dürr R, Tobler I.

Neurobiol Learn Mem. 2006 May;85(3):263-71. Epub 2006 Jan 19.


Stress and arousal: the corticotrophin-releasing factor/hypocretin circuitry.

Winsky-Sommerer R, Boutrel B, de Lecea L.

Mol Neurobiol. 2005 Dec;32(3):285-94. Review.


Expression, synaptic localization, and developmental regulation of Ack1/Pyk1, a cytoplasmic tyrosine kinase highly expressed in the developing and adult brain.

Ureña JM, La Torre A, Martínez A, Lowenstein E, Franco N, Winsky-Sommerer R, Fontana X, Casaroli-Marano R, Ibáñez-Sabio MA, Pascual M, Del Rio JA, de Lecea L, Soriano E.

J Comp Neurol. 2005 Sep 19;490(2):119-32.


The corticotropin-releasing factor-hypocretin connection: implications in stress response and addiction.

Pañeda C, Winsky-Sommerer R, Boutrel B, de Lecea L.

Drug News Perspect. 2005 May;18(4):250-5. Review.


Injection of neuropeptide W into paraventricular nucleus of hypothalamus increases food intake.

Levine AS, Winsky-Sommerer R, Huitron-Resendiz S, Grace MK, de Lecea L.

Am J Physiol Regul Integr Comp Physiol. 2005 Jun;288(6):R1727-32.


Uncoupling protein 2 protects dopaminergic neurons from acute 1,2,3,6-methyl-phenyl-tetrahydropyridine toxicity.

Conti B, Sugama S, Lucero J, Winsky-Sommerer R, Wirz SA, Maher P, Andrews Z, Barr AM, Morale MC, Paneda C, Pemberton J, Gaidarova S, Behrens MM, Beal F, Sanna PP, Horvath T, Bartfai T.

J Neurochem. 2005 Apr;93(2):493-501.


Interaction between the corticotropin-releasing factor system and hypocretins (orexins): a novel circuit mediating stress response.

Winsky-Sommerer R, Yamanaka A, Diano S, Borok E, Roberts AJ, Sakurai T, Kilduff TS, Horvath TL, de Lecea L.

J Neurosci. 2004 Dec 15;24(50):11439-48.


Overexpression of the human beta-amyloid precursor protein downregulates cortistatin mRNA in PDAPP mice.

Winsky-Sommerer R, Spier AD, Fabre V, de Lecea L, Criado JR.

Brain Res. 2004 Oct 8;1023(1):157-62.


The role of the hypocretinergic system in the integration of networks that dictate the states of arousal.

Winsky-Sommerer R, Boutrel B, De Lecea L.

Drug News Perspect. 2003 Oct;16(8):504-12. Review.


The proprotein convertase PC2 is involved in the maturation of prosomatostatin to somatostatin-14 but not in the somatostatin deficit in Alzheimer's disease.

Winsky-Sommerer R, Grouselle D, Rougeot C, Laurent V, David JP, Delacourte A, Dournaud P, Seidah NG, Lindberg I, Trottier S, Epelbaum J.

Neuroscience. 2003;122(2):437-47.


Comparison of somatostatin receptor expression in human gliomas and medulloblastomas.

Cervera P, Videau C, Viollet C, Petrucci C, Lacombe J, Winsky-Sommerer R, Csaba Z, Helboe L, Daumas-Duport C, Reubi JC, Epelbaum J.

J Neuroendocrinol. 2002 Jun;14(6):458-71.


Regional and cellular localization of the neuroendocrine prohormone convertases PC1 and PC2 in the rat central nervous system.

Winsky-Sommerer R, Benjannet S, Rovère C, Barbero P, Seidah NG, Epelbaum J, Dournaud P.

J Comp Neurol. 2000 Aug 28;424(3):439-60.


Loss of somatostatin-like immunoreactivity in the frontal cortex of Alzheimer patients carrying the apolipoprotein epsilon 4 allele.

Grouselle D, Winsky-Sommerer R, David JP, Delacourte A, Dournaud P, Epelbaum J.

Neurosci Lett. 1998 Oct 9;255(1):21-4.


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