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Items: 9

1.

An RNA modification with remarkable resistance to RNase A.

Ghidini A, Ander C, Winqvist A, Strömberg R.

Chem Commun (Camb). 2013 Oct 11;49(79):9036-8. doi: 10.1039/c3cc44621b.

PMID:
23982594
2.

Discovery of 4'-azido-2'-deoxy-2'-C-methyl cytidine and prodrugs thereof: a potent inhibitor of Hepatitis C virus replication.

Nilsson M, Kalayanov G, Winqvist A, Pinho P, Sund C, Zhou XX, Wähling H, Belfrage AK, Pelcman M, Agback T, Benckestock K, Wikström K, Boothee M, Lindqvist A, Rydegård C, Jonckers TH, Vandyck K, Raboisson P, Lin TI, Lachau-Durand S, de Kock H, Smith DB, Martin JA, Klumpp K, Simmen K, Vrang L, Terelius Y, Samuelsson B, Rosenquist S, Johansson NG.

Bioorg Med Chem Lett. 2012 May 1;22(9):3265-8. doi: 10.1016/j.bmcl.2012.03.021. Epub 2012 Mar 16.

PMID:
22472694
3.

Gastrointestinal dysfunction contributes to weight loss in Huntington's disease mice.

van der Burg JM, Winqvist A, Aziz NA, Maat-Schieman ML, Roos RA, Bates GP, Brundin P, Björkqvist M, Wierup N.

Neurobiol Dis. 2011 Oct;44(1):1-8. doi: 10.1016/j.nbd.2011.05.006. Epub 2011 May 23.

PMID:
21624468
4.

The design, synthesis, and antiviral activity of monofluoro and difluoro analogues of 4'-azidocytidine against hepatitis C virus replication: the discovery of 4'-azido-2'-deoxy-2'-fluorocytidine and 4'-azido-2'-dideoxy-2',2'-difluorocytidine.

Smith DB, Kalayanov G, Sund C, Winqvist A, Maltseva T, Leveque VJ, Rajyaguru S, Le Pogam S, Najera I, Benkestock K, Zhou XX, Kaiser AC, Maag H, Cammack N, Martin JA, Swallow S, Johansson NG, Klumpp K, Smith M.

J Med Chem. 2009 May 14;52(9):2971-8. doi: 10.1021/jm801595c.

PMID:
19341305
5.

The design, synthesis, and antiviral activity of 4'-azidocytidine analogues against hepatitis C virus replication: the discovery of 4'-azidoarabinocytidine.

Smith DB, Kalayanov G, Sund C, Winqvist A, Pinho P, Maltseva T, Morisson V, Leveque V, Rajyaguru S, Le Pogam S, Najera I, Benkestock K, Zhou XX, Maag H, Cammack N, Martin JA, Swallow S, Johansson NG, Klumpp K, Smith M.

J Med Chem. 2009 Jan 8;52(1):219-23. doi: 10.1021/jm800981y.

PMID:
19055482
6.

Studies on the stability of dinucleoside H-phosphonates.

Heinonen P, Winqvist A, Sanghvi Y, Strömberg R.

Nucleosides Nucleotides Nucleic Acids. 2003 May-Aug;22(5-8):1387-9.

PMID:
14565425
7.

Preparation of 3'-C-branched uridine analogues, suitable for conversion into functionalised 3'-C-methylene derivatives.

Winqvist A, Strömberg R.

Nucleosides Nucleotides Nucleic Acids. 2001 Apr-Jul;20(4-7):1389-92.

PMID:
11563029
8.

Mechanism of RNase T1: concerted triester-like phosphoryl transfer via a catalytic three-centered hydrogen bond.

Loverix S, Winqvist A, Strömberg R, Steyaert J.

Chem Biol. 2000 Aug;7(8):651-8.

9.

Optical spectroscopic study of the effects of a single deoxyribose substitution in a ribose backbone: implications in RNA-RNA interaction.

Lindqvist M, Sarkar M, Winqvist A, Rozners E, Strömberg R, Gräslund A.

Biochemistry. 2000 Feb 22;39(7):1693-701.

PMID:
10677217

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