Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 94


B cell lymphoma 2 (Bcl-2) residues essential for Bcl-2's apoptosis-inducing interaction with Nur77/Nor-1 orphan steroid receptors.

Banta KL, Wang X, Das P, Winoto A.

J Biol Chem. 2018 Mar 30;293(13):4724-4734. doi: 10.1074/jbc.RA117.001101. Epub 2018 Feb 2.


Induction of necroptotic cell death by viral activation of the RIG-I or STING pathway.

Schock SN, Chandra NV, Sun Y, Irie T, Kitagawa Y, Gotoh B, Coscoy L, Winoto A.

Cell Death Differ. 2017 Apr;24(4):615-625. doi: 10.1038/cdd.2016.153. Epub 2017 Jan 6.


MEF2C and EBF1 Co-regulate B Cell-Specific Transcription.

Kong NR, Davis M, Chai L, Winoto A, Tjian R.

PLoS Genet. 2016 Feb 22;12(2):e1005845. doi: 10.1371/journal.pgen.1005845. eCollection 2016 Feb.


Deletion of FADD in macrophages and granulocytes results in RIP3- and MyD88-dependent systemic inflammation.

Schock SN, Young JA, He TH, Sun Y, Winoto A.

PLoS One. 2015 Apr 13;10(4):e0124391. doi: 10.1371/journal.pone.0124391. eCollection 2015.


Conserved and divergent aspects of human T-cell development and migration in humanized mice.

Halkias J, Yen B, Taylor KT, Reinhartz O, Winoto A, Robey EA, Melichar HJ.

Immunol Cell Biol. 2015 Sep;93(8):716-26. doi: 10.1038/icb.2015.38. Epub 2015 Mar 6.


T cell-specific inhibition of multiple apoptotic pathways blocks negative selection and causes autoimmunity.

Burger ML, Leung KK, Bennett MJ, Winoto A.

Elife. 2014 Sep 2;3. doi: 10.7554/eLife.03468.


Premalignant PTEN-deficient thymocytes activate microRNAs miR-146a and miR-146b as a cellular defense against malignant transformation.

Burger ML, Xue L, Sun Y, Kang C, Winoto A.

Blood. 2014 Jun 26;123(26):4089-100. doi: 10.1182/blood-2013-11-539411. Epub 2014 Apr 15.


Vestibular rehabilitation outcomes in patients with and without vestibular migraine.

Vitkovic J, Winoto A, Rance G, Dowell R, Paine M.

J Neurol. 2013 Dec;260(12):3039-48. doi: 10.1007/s00415-013-7116-7. Epub 2013 Sep 24.


Commensal microbiota are required for systemic inflammation triggered by necrotic dendritic cells.

Young JA, He TH, Reizis B, Winoto A.

Cell Rep. 2013 Jun 27;3(6):1932-44. doi: 10.1016/j.celrep.2013.04.033. Epub 2013 May 30.


Opposing chemokine gradients control human thymocyte migration in situ.

Halkias J, Melichar HJ, Taylor KT, Ross JO, Yen B, Cooper SB, Winoto A, Robey EA.

J Clin Invest. 2013 May;123(5):2131-42. doi: 10.1172/JCI67175. Epub 2013 Apr 15.


Comparative study of hematopoietic differentiation between human embryonic stem cell lines.

Melichar H, Li O, Ross J, Haber H, Cado D, Nolla H, Robey EA, Winoto A.

PLoS One. 2011;6(5):e19854. doi: 10.1371/journal.pone.0019854. Epub 2011 May 16.


Donated breast milk substitutes and incidence of diarrhoea among infants and young children after the May 2006 earthquake in Yogyakarta and Central Java.

Hipgrave DB, Assefa F, Winoto A, Sukotjo S.

Public Health Nutr. 2012 Feb;15(2):307-15. doi: 10.1017/S1368980010003423. Epub 2011 Mar 23.


Fas-associated death domain (FADD) and the E3 ubiquitin-protein ligase TRIM21 interact to negatively regulate virus-induced interferon production.

Young JA, Sermwittayawong D, Kim HJ, Nandu S, An N, Erdjument-Bromage H, Tempst P, Coscoy L, Winoto A.

J Biol Chem. 2011 Feb 25;286(8):6521-31. doi: 10.1074/jbc.M110.172288. Epub 2010 Dec 23.


Fas-associated death domain (FADD) is a negative regulator of T-cell receptor-mediated necroptosis.

Osborn SL, Diehl G, Han SJ, Xue L, Kurd N, Hsieh K, Cado D, Robey EA, Winoto A.

Proc Natl Acad Sci U S A. 2010 Jul 20;107(29):13034-9. doi: 10.1073/pnas.1005997107. Epub 2010 Jul 6.


CD11c+ dendritic cells and B cells contribute to the tumoricidal activity of anti-DR5 antibody therapy in established tumors.

Haynes NM, Hawkins ED, Li M, McLaughlin NM, Hämmerling GJ, Schwendener R, Winoto A, Wensky A, Yagita H, Takeda K, Kershaw MH, Darcy PK, Smyth MJ.

J Immunol. 2010 Jul 1;185(1):532-41. doi: 10.4049/jimmunol.0903624. Epub 2010 May 26.


Protein kinase C regulates mitochondrial targeting of Nur77 and its family member Nor-1 in thymocytes undergoing apoptosis.

Thompson J, Burger ML, Whang H, Winoto A.

Eur J Immunol. 2010 Jul;40(7):2041-9. doi: 10.1002/eji.200940231.


FoxM1, a forkhead transcription factor is a master cell cycle regulator for mouse mature T cells but not double positive thymocytes.

Xue L, Chiang L, He B, Zhao YY, Winoto A.

PLoS One. 2010 Feb 16;5(2):e9229. doi: 10.1371/journal.pone.0009229.


Coupling of the cell cycle and apoptotic machineries in developing T cells.

Xue L, Sun Y, Chiang L, He B, Kang C, Nolla H, Winoto A.

J Biol Chem. 2010 Mar 5;285(10):7556-65. doi: 10.1074/jbc.M109.035535. Epub 2010 Jan 12.


The role of the PI3K-AKT kinase pathway in T-cell development beyond the beta checkpoint.

Xue L, Chiang L, Kang C, Winoto A.

Eur J Immunol. 2008 Nov;38(11):3200-7. doi: 10.1002/eji.200838614.


Non-redundant function of the MEK5-ERK5 pathway in thymocyte apoptosis.

Sohn SJ, Lewis GM, Winoto A.

EMBO J. 2008 Jul 9;27(13):1896-906. doi: 10.1038/emboj.2008.114. Epub 2008 Jun 12.


During negative selection, Nur77 family proteins translocate to mitochondria where they associate with Bcl-2 and expose its proapoptotic BH3 domain.

Thompson J, Winoto A.

J Exp Med. 2008 May 12;205(5):1029-36. doi: 10.1084/jem.20080101. Epub 2008 Apr 28.


Normal development is an integral part of tumorigenesis in T cell-specific PTEN-deficient mice.

Xue L, Nolla H, Suzuki A, Mak TW, Winoto A.

Proc Natl Acad Sci U S A. 2008 Feb 12;105(6):2022-7. doi: 10.1073/pnas.0712059105. Epub 2008 Feb 4.


Apoptosis during negative selection of autoreactive thymocytes.

Sohn SJ, Thompson J, Winoto A.

Curr Opin Immunol. 2007 Oct;19(5):510-5. Epub 2007 Jul 25. Review.


Constitutive phosphorylation mutation in Fas-associated death domain (FADD) results in early cell cycle defects.

Osborn SL, Sohn SJ, Winoto A.

J Biol Chem. 2007 Aug 3;282(31):22786-92. Epub 2007 Jun 6.


Transcriptional regulation of tissue-specific genes by the ERK5 mitogen-activated protein kinase.

Sohn SJ, Li D, Lee LK, Winoto A.

Mol Cell Biol. 2005 Oct;25(19):8553-66.


Phosphorylation of FADD at serine 194 by CKIalpha regulates its nonapoptotic activities.

Alappat EC, Feig C, Boyerinas B, Volkland J, Samuels M, Murmann AE, Thorburn A, Kidd VJ, Slaughter CA, Osborn SL, Winoto A, Tang WJ, Peter ME.

Mol Cell. 2005 Aug 5;19(3):321-32.


Reduction of the incidence and severity of collagen-induced arthritis by constitutive Nur77 expression in the T cell lineage.

De Silva S, Han S, Zhang X, Huston DP, Winoto A, Zheng B.

Arthritis Rheum. 2005 Jan;52(1):333-8.


TRAIL-R as a negative regulator of innate immune cell responses.

Diehl GE, Yue HH, Hsieh K, Kuang AA, Ho M, Morici LA, Lenz LL, Cado D, Riley LW, Winoto A.

Immunity. 2004 Dec;21(6):877-89.


Loss of TRAIL-R does not affect thymic or intestinal tumor development in p53 and adenomatous polyposis coli mutant mice.

Yue HH, Diehl GE, Winoto A.

Cell Death Differ. 2005 Jan;12(1):94-7. No abstract available.


Cutting into innate immunity.

Winoto A.

Nat Immunol. 2004 Jun;5(6):563-4. No abstract available.


Distinct transcriptional programs in thymocytes responding to T cell receptor, Notch, and positive selection signals.

Huang YH, Li D, Winoto A, Robey EA.

Proc Natl Acad Sci U S A. 2004 Apr 6;101(14):4936-41. Epub 2004 Mar 25.


Essential role of survivin, an inhibitor of apoptosis protein, in T cell development, maturation, and homeostasis.

Xing Z, Conway EM, Kang C, Winoto A.

J Exp Med. 2004 Jan 5;199(1):69-80. Epub 2003 Dec 29.


Transcriptional activation of known and novel apoptotic pathways by Nur77 orphan steroid receptor.

Rajpal A, Cho YA, Yelent B, Koza-Taylor PH, Li D, Chen E, Whang M, Kang C, Turi TG, Winoto A.

EMBO J. 2003 Dec 15;22(24):6526-36.


The orphan steroid receptor Nur77 family member Nor-1 is essential for early mouse embryogenesis.

DeYoung RA, Baker JC, Cado D, Winoto A.

J Biol Chem. 2003 Nov 21;278(47):47104-9. Epub 2003 Sep 16.


Apoptosis during lymphoid development.

Sohn SJ, Rajpal A, Winoto A.

Curr Opin Immunol. 2003 Apr;15(2):209-16. Review.


ERK5 MAPK regulates embryonic angiogenesis and acts as a hypoxia-sensitive repressor of vascular endothelial growth factor expression.

Sohn SJ, Sarvis BK, Cado D, Winoto A.

J Biol Chem. 2002 Nov 8;277(45):43344-51. Epub 2002 Sep 6.


Nuclear hormone receptors in T lymphocytes.

Winoto A, Littman DR.

Cell. 2002 Apr;109 Suppl:S57-66. Review.


Function and factor interactions of a locus control region element in the mouse T cell receptor-alpha/Dad1 gene locus.

Ortiz BD, Harrow F, Cado D, Santoso B, Winoto A.

J Immunol. 2001 Oct 1;167(7):3836-45.


FADD-deficient T cells exhibit a disaccord in regulation of the cell cycle machinery.

Zhang J, Kabra NH, Cado D, Kang C, Winoto A.

J Biol Chem. 2001 Aug 10;276(32):29815-8. Epub 2001 Jun 4.


T cell-specific FADD-deficient mice: FADD is required for early T cell development.

Kabra NH, Kang C, Hsing LC, Zhang J, Winoto A.

Proc Natl Acad Sci U S A. 2001 May 22;98(11):6307-12. Epub 2001 May 15.


Receptor-mediated apoptosis in T lymphocytes.

Zhang J, DeYoung A, Kasler HG, Kabra NH, Kuang AA, Diehl G, Sohn SJ, Bishop C, Winoto A.

Cold Spring Harb Symp Quant Biol. 1999;64:363-71. Review. No abstract available.


The TNF receptor family member CD30 is not essential for negative selection.

DeYoung AL, Duramad O, Winoto A.

J Immunol. 2000 Dec 1;165(11):6170-3.


ERK5 is a novel type of mitogen-activated protein kinase containing a transcriptional activation domain.

Kasler HG, Victoria J, Duramad O, Winoto A.

Mol Cell Biol. 2000 Nov;20(22):8382-9.


Inhibition of Fas-mediated apoptosis by the B cell antigen receptor through c-FLIP.

Wang J, Lobito AA, Shen F, Hornung F, Winoto A, Lenardo MJ.

Eur J Immunol. 2000 Jan;30(1):155-63.


Nur77 transcription activity correlates with its apoptotic function in vivo.

Kuang AA, Cado D, Winoto A.

Eur J Immunol. 1999 Nov;29(11):3722-8.


Supplemental Content

Loading ...
Support Center