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Items: 1 to 50 of 137

1.

Efficacy of Esketamine Nasal Spray Plus Oral Antidepressant Treatment for Relapse Prevention in Patients With Treatment-Resistant Depression: A Randomized Clinical Trial.

Daly EJ, Trivedi MH, Janik A, Li H, Zhang Y, Li X, Lane R, Lim P, Duca AR, Hough D, Thase ME, Zajecka J, Winokur A, Divacka I, Fagiolini A, Cubala WJ, Bitter I, Blier P, Shelton RC, Molero P, Manji H, Drevets WC, Singh JB.

JAMA Psychiatry. 2019 Jun 5. doi: 10.1001/jamapsychiatry.2019.1189. [Epub ahead of print]

2.

The Opioid Epidemic: Moving Toward an Integrated, Holistic Analytical Response.

Morrow JB, Ropero-Miller JD, Catlin ML, Winokur AD, Cadwallader AB, Staymates JL, Williams SR, McGrath JG, Logan BK, McCormick MM, Nolte KB, Gilson TP, Menendez MJ, Goldberger BA.

J Anal Toxicol. 2019 Jan 1;43(1):1-9. doi: 10.1093/jat/bky049. Review.

PMID:
30165647
3.

Efficacy and Safety of Intranasal Esketamine Adjunctive to Oral Antidepressant Therapy in Treatment-Resistant Depression: A Randomized Clinical Trial.

Daly EJ, Singh JB, Fedgchin M, Cooper K, Lim P, Shelton RC, Thase ME, Winokur A, Van Nueten L, Manji H, Drevets WC.

JAMA Psychiatry. 2018 Feb 1;75(2):139-148. doi: 10.1001/jamapsychiatry.2017.3739.

4.

Sleep Patterns and Neuropsychiatric Symptoms in Hospitalized Patients With Dementia.

Tanev KS, Winokur A, Pitman RK.

J Neuropsychiatry Clin Neurosci. 2017 Summer;29(3):248-253. doi: 10.1176/appi.neuropsych.16090166. Epub 2017 Mar 15.

5.

The neurologist's role in supporting transition to adult health care: A consensus statement.

Brown LW, Camfield P, Capers M, Cascino G, Ciccarelli M, de Gusmao CM, Downs SM, Majnemer A, Miller AB, SanInocencio C, Schultz R, Tilton A, Winokur A, Zupanc M.

Neurology. 2016 Aug 23;87(8):835-40. doi: 10.1212/WNL.0000000000002965. Epub 2016 Jul 27.

PMID:
27466477
6.

A Double-Blind, Randomized, Placebo-Controlled, Dose-Frequency Study of Intravenous Ketamine in Patients With Treatment-Resistant Depression.

Singh JB, Fedgchin M, Daly EJ, De Boer P, Cooper K, Lim P, Pinter C, Murrough JW, Sanacora G, Shelton RC, Kurian B, Winokur A, Fava M, Manji H, Drevets WC, Van Nueten L.

Am J Psychiatry. 2016 Aug 1;173(8):816-26. doi: 10.1176/appi.ajp.2016.16010037. Epub 2016 Apr 8.

PMID:
27056608
7.

Sleep Disorders and Mental Health.

Winokur A, Kamath J.

Psychiatr Clin North Am. 2015 Dec;38(4):xiii-xiv. doi: 10.1016/j.psc.2015.08.003. Epub 2015 Aug 28. No abstract available.

PMID:
26600113
8.

Sleep Disturbances in Schizophrenia.

Kamath J, Virdi S, Winokur A.

Psychiatr Clin North Am. 2015 Dec;38(4):777-92. doi: 10.1016/j.psc.2015.07.007. Epub 2015 Aug 22. Review.

PMID:
26600108
9.

The Relationship Between Sleep Disturbances and Psychiatric Disorders: Introduction and Overview.

Winokur A.

Psychiatr Clin North Am. 2015 Dec;38(4):603-14. doi: 10.1016/j.psc.2015.07.001. Review.

PMID:
26600099
10.

A 12-week, randomized, double-blind, placebo-controlled, sequential parallel comparison trial of ziprasidone as monotherapy for major depressive disorder.

Papakostas GI, Vitolo OV, Ishak WW, Rapaport MH, Zajecka JM, Kinrys G, Mischoulon D, Lipkin SH, Hails KA, Abrams J, Ward SG, Meisner A, Schoenfeld DA, Shelton RC, Winokur A, Okasha MS, Bari MA, Fava M.

J Clin Psychiatry. 2012 Dec;73(12):1541-7. doi: 10.4088/JCP.12m07670.

PMID:
23290327
11.

Thyrotropin-releasing hormone as a treatment for cancer-related fatigue: a randomized controlled study.

Kamath J, Feinn R, Winokur A.

Support Care Cancer. 2012 Aug;20(8):1745-53. doi: 10.1007/s00520-011-1268-8. Epub 2011 Sep 27.

PMID:
21947558
12.

Thyrotropin-releasing hormone can relieve cancer-related fatigue: hypothesis and preliminary observations.

Kamath J, Yarbrough GG, Prange AJ Jr, Winokur A.

J Int Med Res. 2009 Jul-Aug;37(4):1152-7.

PMID:
19761698
13.

New approaches for the treatment of sleep disorders.

DeMartinis NA, Kamath J, Winokur A.

Adv Pharmacol. 2009;57:187-235. doi: 10.1016/S1054-3589(08)57005-0. Epub 2009 Nov 27. Review.

PMID:
20230762
14.

The thyrotropin-releasing hormone (TRH)-immune system homeostatic hypothesis.

Kamath J, Yarbrough GG, Prange AJ Jr, Winokur A.

Pharmacol Ther. 2009 Jan;121(1):20-8. doi: 10.1016/j.pharmthera.2008.09.004. Epub 2008 Oct 21. Review.

PMID:
19000920
15.

Thyrotropin-releasing hormone (TRH) in the neuroaxis: therapeutic effects reflect physiological functions and molecular actions.

Yarbrough GG, Kamath J, Winokur A, Prange AJ Jr.

Med Hypotheses. 2007;69(6):1249-56. Epub 2007 Jun 5.

PMID:
17553626
16.

Effects of psychiatric medications on sleep and sleep disorders.

DeMartinis NA, Winokur A.

CNS Neurol Disord Drug Targets. 2007 Feb;6(1):17-29. Review.

PMID:
17305551
17.

Self-criticism and depressive symptomatology interact to predict middle school academic achievement.

Shahar G, Henrich CC, Winokur A, Blatt SJ, Kuperminc GP, Leadbeater BJ.

J Clin Psychol. 2006 Jan;62(1):147-55.

PMID:
16287148
18.

Rapid antidepressant response after nocturnal TRH administration in patients with bipolar type I and bipolar type II major depression.

Szuba MP, Amsterdam JD, Fernando AT 3rd, Gary KA, Whybrow PC, Winokur A.

J Clin Psychopharmacol. 2005 Aug;25(4):325-30. Erratum in: J Clin Psychopharmacol. 2005 Dec;25(6):538. Fernando, Antonio T 3rd [added]; Gary, Keith A [added]; Whybrow, Peter C [added]; Winokur, Andrew [added].

PMID:
16012274
19.

Amantadine for weight gain associated with olanzapine treatment.

Deberdt W, Winokur A, Cavazzoni PA, Trzaskoma QN, Carlson CD, Bymaster FP, Wiener K, Floris M, Breier A.

Eur Neuropsychopharmacol. 2005 Jan;15(1):13-21.

PMID:
15572269
20.

Demonstration of the efficacy and safety of a novel substance P (NK1) receptor antagonist in major depression.

Kramer MS, Winokur A, Kelsey J, Preskorn SH, Rothschild AJ, Snavely D, Ghosh K, Ball WA, Reines SA, Munjack D, Apter JT, Cunningham L, Kling M, Bari M, Getson A, Lee Y.

Neuropsychopharmacology. 2004 Feb;29(2):385-92.

21.

Comparative effects of mirtazapine and fluoxetine on sleep physiology measures in patients with major depression and insomnia.

Winokur A, DeMartinis NA 3rd, McNally DP, Gary EM, Cormier JL, Gary KA.

J Clin Psychiatry. 2003 Oct;64(10):1224-9.

PMID:
14658972
22.

The thyrotropin-releasing hormone (TRH) hypothesis of homeostatic regulation: implications for TRH-based therapeutics.

Gary KA, Sevarino KA, Yarbrough GG, Prange AJ Jr, Winokur A.

J Pharmacol Exp Ther. 2003 May;305(2):410-6. Epub 2003 Feb 20. Review.

PMID:
12606661
23.

Lysophosphatidic acid induction of tissue factor expression in aortic smooth muscle cells.

Cui MZ, Zhao G, Winokur AL, Laag E, Bydash JR, Penn MS, Chisolm GM, Xu X.

Arterioscler Thromb Vasc Biol. 2003 Feb 1;23(2):224-30.

PMID:
12588763
24.

Depression, sleep physiology, and antidepressant drugs.

Winokur A, Gary KA, Rodner S, Rae-Red C, Fernando AT, Szuba MP.

Depress Anxiety. 2001;14(1):19-28. Review.

PMID:
11568979
25.

Smooth muscle cell surface tissue factor pathway activation by oxidized low-density lipoprotein requires cellular lipid peroxidation.

Penn MS, Cui MZ, Winokur AL, Bethea J, Hamilton TA, DiCorleto PE, Chisolm GM.

Blood. 2000 Nov 1;96(9):3056-63.

PMID:
11049984
26.

Acute effects of mirtazapine on sleep continuity and sleep architecture in depressed patients: a pilot study.

Winokur A, Sateia MJ, Hayes JB, Bayles-Dazet W, MacDonald MM, Gary KA.

Biol Psychiatry. 2000 Jul 1;48(1):75-8.

PMID:
10913511
27.

Association between subjective sleep quality and depression on immunocompetence in low-income women at risk for cervical cancer.

Savard J, Miller SM, Mills M, O'Leary A, Harding H, Douglas SD, Mangan CE, Belch R, Winokur A.

Psychosom Med. 1999 Jul-Aug;61(4):496-507. Review.

PMID:
10443758
28.

CSF thyrotropin-releasing hormone gender difference: implications for neurobiology and treatment of depression.

Frye MA, Gary KA, Marangell LB, George MS, Callahan AM, Little JT, Huggins T, CorĂ¡-Locatelli G, Osuch EA, Winokur A, Post RM.

J Neuropsychiatry Clin Neurosci. 1999 Summer;11(3):349-53.

PMID:
10440011
29.

Lack of correlation between cerebrospinal fluid thyrotropin-releasing hormone (TRH) and TRH-stimulated thyroid-stimulating hormone in patients with depression.

Frye MA, Dunn RT, Gary KA, Kimbrell TA, Callahan AM, Luckenbaugh DA, CorĂ¡-Locatelli G, Vanderham E, Winokur A, Post RM.

Biol Psychiatry. 1999 Apr 15;45(8):1049-52.

PMID:
10386189
30.

Comparative effects of nefazodone and fluoxetine on sleep in outpatients with major depressive disorder.

Rush AJ, Armitage R, Gillin JC, Yonkers KA, Winokur A, Moldofsky H, Vogel GW, Kaplita SB, Fleming JB, Montplaisir J, Erman MK, Albala BJ, McQuade RD.

Biol Psychiatry. 1998 Jul 1;44(1):3-14.

PMID:
9646878
31.

A comparison of nefazodone and fluoxetine on mood and on objective, subjective, and clinician-rated measures of sleep in depressed patients: a double-blind, 8-week clinical trial.

Gillin JC, Rapaport M, Erman MK, Winokur A, Albala BJ.

J Clin Psychiatry. 1997 May;58(5):185-92. Erratum in: J Clin Psychiatry 1997 Jun;58(6):275.

PMID:
9184611
32.

Thyrotropin-releasing hormone phase shifts circadian rhythms in hamsters.

Gary KA, Sollars PJ, Lexow N, Winokur A, Pickard GE.

Neuroreport. 1996 Jul 8;7(10):1631-4.

PMID:
8904771
33.

Total sleep deprivation and the thyroid axis: effects of sleep and waking activity.

Gary KA, Winokur A, Douglas SD, Kapoor S, Zaugg L, Dinges DF.

Aviat Space Environ Med. 1996 Jun;67(6):513-9.

PMID:
8827131
34.

Peptide mimetics of thyrotropin-releasing hormone based on a cyclohexane framework: design, synthesis, and cognition-enhancing properties.

Olson GL, Cheung HC, Chiang E, Madison VS, Sepinwall J, Vincent GP, Winokur A, Gary KA.

J Med Chem. 1995 Jul 21;38(15):2866-79.

PMID:
7636847
35.

Alterations in TRH receptors in temporal lobe of schizophrenics: a quantitative autoradiographic study.

Lexow N, Joyce JN, Kim SJ, Phillips J, Casanova MF, Bird ED, Kleinman JE, Winokur A.

Synapse. 1994 Dec;18(4):315-27.

PMID:
7886624
36.

Serotonin uptake sites and serotonin receptors are altered in the limbic system of schizophrenics.

Joyce JN, Shane A, Lexow N, Winokur A, Casanova MF, Kleinman JE.

Neuropsychopharmacology. 1993 Jun;8(4):315-36.

37.

Thyroid function before and after four-week light treatment in winter depressives and controls.

Bauer MS, Kurtz J, Winokur A, Phillips J, Rubin LB, Marcus JG.

Psychoneuroendocrinology. 1993;18(5-6):437-43.

PMID:
8416052
38.

Seasonal and state-dependent changes in brain TRH receptors in hibernating ground squirrels.

Stanton TL, Caine SB, Winokur A.

Brain Res Bull. 1992 Jun;28(6):877-86.

PMID:
1322229
39.

Distribution of beta-adrenergic receptor subtypes in human post-mortem brain: alterations in limbic regions of schizophrenics.

Joyce JN, Lexow N, Kim SJ, Artymyshyn R, Senzon S, Lawrence D, Cassanova MF, Kleinman JE, Bird ED, Winokur A.

Synapse. 1992 Mar;10(3):228-46.

PMID:
1313605
40.

Rapid cycling bipolar affective disorder. I. Association with grade I hypothyroidism.

Bauer MS, Whybrow PC, Winokur A.

Arch Gen Psychiatry. 1990 May;47(5):427-32.

PMID:
2109970
41.

Systemic administration of kainic acid produces elevations in TRH in rat central nervous system.

Kreider MS, Wolfinger BL, Winokur A.

Regul Pept. 1990 Mar 27;28(1):83-93.

PMID:
2109340
42.

Reduction of thyrotropin-releasing hormone concentrations in central nervous system of African lungfish during estivation.

Kreider MS, Winokur A, Pack AI, Fishman AP.

Gen Comp Endocrinol. 1990 Mar;77(3):435-41.

PMID:
2110919
43.

Autoradiographic distribution of thyrotropin-releasing hormone receptors in the African lungfish Protopterus annectens.

Pack AM, Caine SB, Winokur A, Manaker S, Fishman AP.

J Comp Neurol. 1989 Sep 1;287(1):19-27.

PMID:
2551933
44.

Multiple hormone responses to clonidine administration in depressed patients and healthy volunteers.

Amsterdam JD, Maislin G, Skolnick B, Berwish N, Winokur A.

Biol Psychiatry. 1989 Jul;26(3):265-78.

PMID:
2742943
45.

Enhanced adrenocortical sensitivity to submaximal doses of cosyntropin (alpha1-24-corticotropin) in depressed patients.

Amsterdam JD, Maislin G, Berwish N, Phillips J, Winokur A.

Arch Gen Psychiatry. 1989 Jun;46(6):550-4.

PMID:
2730279
46.

Factors contributing to erythrocyte lithium-sodium countertransport activity in lithium-treated bipolar patients.

Rybakowski JK, Amsterdam JD, Dyson WL, Frazer A, Winokur A, Kurtz J.

Pharmacopsychiatry. 1989 Jan;22(1):16-20.

PMID:
2710807
47.

Post-mortem stability of thyrotropin-releasing hormone and muscarinic cholinergic receptors in rat forebrain.

Manaker S, Lipson D, Lexow N, Wieczorek CM, Winokur A.

Synapse. 1989;4(4):387-9. No abstract available.

PMID:
2557687
48.
49.

TRH and TRH receptors in the spinal cord.

Winokur A, Manaker S, Kreider MS.

Ann N Y Acad Sci. 1989;553:314-24. Review.

PMID:
2541651
50.

Characterization of thyrotropin-releasing hormone in the central nervous system of African lungfish.

Kreider MS, Winokur A, Manaker S, Pack AI, Fishman AP.

Gen Comp Endocrinol. 1988 Oct;72(1):115-22.

PMID:
3141242

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