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Items: 1 to 50 of 160

1.

Mass Spectrometry-Based Tissue Imaging: The Next Frontier in Clinical Diagnostics?

Leung F, Eberlin LS, Schwamborn K, Heeren RMA, Winograd N, Cooks RG.

Clin Chem. 2019 Feb 8. pii: clinchem.2018.289694. doi: 10.1373/clinchem.2018.289694. [Epub ahead of print] No abstract available.

PMID:
30737204

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2.

Secondary-Ion Mass Spectrometry Images Cardiolipins and Phosphatidylethanolamines at the Subcellular Level.

Tian H, Sparvero LJ, Blenkinsopp P, Amoscato AA, Watkins SC, Bayır H, Kagan VE, Winograd N.

Angew Chem Int Ed Engl. 2019 Jan 24. doi: 10.1002/anie.201814256. [Epub ahead of print]

PMID:
30680861

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3.

C-O Bond Dissociation and Induced Chemical Ionization Using High Energy (CO2)n+ Gas Cluster Ion Beam.

Tian H, Maciążek D, Postawa Z, Garrison BJ, Winograd N.

J Am Soc Mass Spectrom. 2018 Nov 14. doi: 10.1007/s13361-018-2102-z. [Epub ahead of print]

PMID:
30430438

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4.

Gas Cluster Ion Beams for Secondary Ion Mass Spectrometry.

Winograd N.

Annu Rev Anal Chem (Palo Alto Calif). 2018 Jun 12;11(1):29-48. doi: 10.1146/annurev-anchem-061516-045249. Epub 2018 Feb 28.

PMID:
29490191

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5.

Subcellular Chemical Imaging of Antibiotics in Single Bacteria Using C60-Secondary Ion Mass Spectrometry.

Tian H, Six DA, Krucker T, Leeds JA, Winograd N.

Anal Chem. 2017 May 2;89(9):5050-5057. doi: 10.1021/acs.analchem.7b00466. Epub 2017 Apr 15.

PMID:
28332827
Free PMC Article

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6.

Gas Cluster Ion Beam Time-of-Flight Secondary Ion Mass Spectrometry High-Resolution Imaging of Cardiolipin Speciation in the Brain: Identification of Molecular Losses after Traumatic Injury.

Tian H, Sparvero LJ, Amoscato AA, Bloom A, Bayır H, Kagan VE, Winograd N.

Anal Chem. 2017 Apr 18;89(8):4611-4619. doi: 10.1021/acs.analchem.7b00164. Epub 2017 Mar 29.

PMID:
28306235
Free PMC Article

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7.

Label-free visualization of nilotinib-functionalized gold nanoparticles within single mammalian cells by C60- SIMS imaging.

Bloom AN, Tian H, Schoen C, Winograd N.

Anal Bioanal Chem. 2017 May;409(12):3067-3076. doi: 10.1007/s00216-017-0262-5. Epub 2017 Mar 10.

PMID:
28283715

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8.

On the SIMS Ionization Probability of Organic Molecules.

Popczun NJ, Breuer L, Wucher A, Winograd N.

J Am Soc Mass Spectrom. 2017 Jun;28(6):1182-1191. doi: 10.1007/s13361-017-1624-0. Epub 2017 Mar 6.

PMID:
28265969

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9.

Reducing the Matrix Effect in Organic Cluster SIMS Using Dynamic Reactive Ionization.

Tian H, Wucher A, Winograd N.

J Am Soc Mass Spectrom. 2016 Dec;27(12):2014-2024. Epub 2016 Sep 22.

PMID:
27659034
Free PMC Article

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10.

CO2 Cluster Ion Beam, an Alternative Projectile for Secondary Ion Mass Spectrometry.

Tian H, Maciążek D, Postawa Z, Garrison BJ, Winograd N.

J Am Soc Mass Spectrom. 2016 Sep;27(9):1476-82. doi: 10.1007/s13361-016-1423-z. Epub 2016 Jun 20.

PMID:
27324648
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11.

Reduce the matrix effect in biological tissue imaging using dynamic reactive ionization and gas cluster ion beams.

Tian H, Wucher A, Winograd N.

Biointerphases. 2016 Jun 8;11(2):02A320. doi: 10.1116/1.4941366.

PMID:
26856333
Free PMC Article

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12.

Multimodal image fusion with SIMS: Preprocessing with image registration.

Tarolli JG, Bloom A, Winograd N.

Biointerphases. 2016 Jun 14;11(2):02A311. doi: 10.1116/1.4939892.

PMID:
26772745
Free PMC Article

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13.

Cluster secondary ion mass spectrometry imaging of interfacial reactions of TiO2 microspheres embedded in ionic liquids.

Shen K, Tarolli JG, Winograd N.

Rapid Commun Mass Spectrom. 2016 Feb 15;30(3):379-85. doi: 10.1002/rcm.7447.

PMID:
26754130

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14.

C60-SIMS imaging of nanoparticles within mammalian cells.

Bloom AN, Tian H, Winograd N.

Biointerphases. 2015 Jul 1;11(2):02A306. doi: 10.1116/1.4939463.

PMID:
26721414
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15.

Investigations Into the Interactions of a MALDI Matrix with Organic Thin Films Using C60+ SIMS Depth Profiling.

Lerach JO, Keskin S, Winograd N.

Surf Interface Anal. 2014 Nov;46(Suppl 1):67-69. Epub 2014 May 15.

PMID:
26494930
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16.

Correction to Measuring Compositions in Organic Depth Profiling: Results from a VAMAS Interlaboratory Study.

Shard AG, Havelund R, Spencer SJ, Gilmore IS, Alexander MR, Angerer TB, Aoyagi S, Barnes JP, Benayad A, Bernasik A, Ceccone G, Counsell JD, Deeks C, Fletcher JS, Graham DJ, Heuser C, Lee TG, Marie C, Marzec MM, Mishra G, Rading D, Renault O, Scurr DJ, Shon HK, Spampinato V, Tian H, Wang F, Winograd N, Wu K, Wucher A, Zhou Y, Zhu Z, Cristaudo V, Poleunis C.

J Phys Chem B. 2015 Nov 5;119(44):14337. doi: 10.1021/acs.jpcb.5b09767. Epub 2015 Oct 15. No abstract available.

PMID:
26469795

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17.

Dynamic Reactive Ionization with Cluster Secondary Ion Mass Spectrometry.

Tian H, Wucher A, Winograd N.

J Am Soc Mass Spectrom. 2016 Feb;27(2):285-92. doi: 10.1007/s13361-015-1283-y.

PMID:
26463238
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18.

Molecular imaging of biological tissue using gas cluster ions.

Tian H, Wucher A, Winograd N.

Surf Interface Anal. 2014 Nov;46(1):115-117.

PMID:
26207076
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19.

Measuring Compositions in Organic Depth Profiling: Results from a VAMAS Interlaboratory Study.

Shard AG, Havelund R, Spencer SJ, Gilmore IS, Alexander MR, Angerer TB, Aoyagi S, Barnes JP, Benayad A, Bernasik A, Ceccone G, Counsell JD, Deeks C, Fletcher JS, Graham DJ, Heuser C, Lee TG, Marie C, Marzec MM, Mishra G, Rading D, Renault O, Scurr DJ, Shon HK, Spampinato V, Tian H, Wang F, Winograd N, Wu K, Wucher A, Zhou Y, Zhu Z, Cristaudo V, Poleunis C.

J Phys Chem B. 2015 Aug 20;119(33):10784-97. doi: 10.1021/acs.jpcb.5b05625. Epub 2015 Aug 6. Erratum in: J Phys Chem B. 2015 Nov 5;119(44):14337. Cristaudo, Vanina [added]; Poleunis, Claude [added].

PMID:
26204428

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20.

Dye-Enhanced imaging of mammalian cells with SIMS.

Bloom A, Winograd N.

Surf Interface Anal. 2014 Nov;46(Suppl 1):177-180.

PMID:
25931643
Free PMC Article

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21.

Imaging mass spectrometry on the nanoscale with cluster ion beams.

Winograd N.

Anal Chem. 2015 Jan 6;87(1):328-33. doi: 10.1021/ac503650p. Epub 2014 Dec 17.

PMID:
25458665
Free PMC Article

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22.

Sample preparation for 3D SIMS chemical imaging of cells.

Winograd N, Bloom A.

Methods Mol Biol. 2015;1203:9-19. doi: 10.1007/978-1-4939-1357-2_2.

PMID:
25361662
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23.

Relative ion yields in mammalian cell components using C60 SIMS.

Keskin S, Piwowar A, Hue J, Shen K, Winograd N.

Surf Interface Anal. 2014 Jan 1;45(1):244-247.

PMID:
25140069
Free PMC Article

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24.

Near infrared (NIR) strong field ionization and imaging of C₆₀ sputtered molecules: overcoming matrix effects and improving sensitivity.

Kucher A, Jackson LM, Lerach JO, Bloom AN, Popczun NJ, Wucher A, Winograd N.

Anal Chem. 2014 Sep 2;86(17):8613-20. doi: 10.1021/ac501586d. Epub 2014 Aug 19.

PMID:
25109240

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25.

Improving secondary ion mass spectrometry image quality with image fusion.

Tarolli JG, Jackson LM, Winograd N.

J Am Soc Mass Spectrom. 2014 Dec;25(12):2154-62. doi: 10.1007/s13361-014-0927-7. Epub 2014 Jun 10.

PMID:
24912432
Free PMC Article

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26.

Formation of neutral In(m)C(n) clusters under C60 ion bombardment of indium.

Breuer L, Kucher A, Herder M, Wucher A, Winograd N.

J Phys Chem A. 2014 Sep 18;118(37):8542-52. doi: 10.1021/jp5024247. Epub 2014 May 15.

PMID:
24779393

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27.

A mixed cluster ion beam to enhance the ionization efficiency in molecular secondary ion mass spectrometry.

Wucher A, Tian H, Winograd N.

Rapid Commun Mass Spectrom. 2014 Feb 28;28(4):396-400. doi: 10.1002/rcm.6793.

PMID:
24395507
Free PMC Article

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28.

Evidence for the formation of dynamically created pre-formed ions at the interface of isotopically enriched thin films.

Lerach JO, Winograd N.

Surf Interface Anal. 2013 Jan 1;45(1). doi: 10.1002/sia.5102.

PMID:
24353354
Free PMC Article

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29.

Depth profiling of metal overlayers on organic substrates with cluster SIMS.

Shen K, Mao D, Garrison BJ, Wucher A, Winograd N.

Anal Chem. 2013 Nov 5;85(21):10565-72. doi: 10.1021/ac402658r. Epub 2013 Oct 10.

PMID:
24070427

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30.

C60-ToF SIMS imaging of frozen hydrated HeLa cells.

Piwowar AM, Keskin S, Delgado MO, Shen K, Hue JJ, Lanekoff I, Ewing AG, Winograd N.

Surf Interface Anal. 2013 Jan 1;45(1):302-304.

PMID:
23585702
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31.

Direct observation of ion distributions near electrodes in ionic polymer actuators containing ionic liquids.

Liu Y, Lu C, Twigg S, Ghaffari M, Lin J, Winograd N, Zhang QM.

Sci Rep. 2013;3:973. doi: 10.1038/srep00973.

PMID:
23512124
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32.

Temperature Effects of Sputtering of Langmuir-Blodgett Multilayers.

Mao D, Brenes DA, Lu C, Wucher A, Winograd N.

Surf Interface Anal. 2013 Jan 1;45(1):65-67. Epub 2012 Jul 6.

PMID:
23397359
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33.

Single-cell lipidomics: characterizing and imaging lipids on the surface of individual Aplysia californica neurons with cluster secondary ion mass spectrometry.

Passarelli MK, Ewing AG, Winograd N.

Anal Chem. 2013 Feb 19;85(4):2231-8. doi: 10.1021/ac303038j. Epub 2013 Feb 4.

PMID:
23323749
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34.

An experimental and theoretical view of energetic C60 cluster bombardment onto molecular solids.

Brenes DA, Postawa Z, Wucher A, Blenkinsopp P, Garrison BJ, Winograd N.

Surf Interface Anal. 2013 Jan 1;45(1):50-53.

PMID:
26311917
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35.

Molecular Depth Profiling.

Winograd N.

Surf Interface Anal. 2013 Jan 1;45(1):3-8. No abstract available.

PMID:
26290616
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36.

Quantitative Detection of Purines in Biologically-Relevant Films with TOF-Secondary Ion Mass Spectrometry.

Jackson LM, Hue JJ, Winograd N.

Surf Interface Anal. 2013 Jan 1;45(1):237-239.

PMID:
25009363
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37.

C(60)-SIMS Studies of Glycerophospholipid in a LIPID MAPS Model System: KDO(2)-Lipid A Stimulated RAW 264.7 Cells.

Passarelli MK, Ewing AG, Winograd N.

Surf Interface Anal. 2013 Jan 1;45(1):298-301. Epub 2012 May 3.

PMID:
23264707
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38.

Mass spectrometry imaging of freeze-dried membrane phospholipids of dividing Tetrahymena pyriformis.

Lanekoff I, Phan NT, Van Bell CT, Winograd N, Sjövall P, Ewing AG.

Surf Interface Anal. 2013 Jan 1;45(1):211-214. Epub 2012 Jun 14.

PMID:
23264706
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39.

Argon cluster ion beams for organic depth profiling: results from a VAMAS interlaboratory study.

Shard AG, Havelund R, Seah MP, Spencer SJ, Gilmore IS, Winograd N, Mao D, Miyayama T, Niehuis E, Rading D, Moellers R.

Anal Chem. 2012 Sep 18;84(18):7865-73. doi: 10.1021/ac301567t. Epub 2012 Sep 5.

PMID:
22897795

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40.

Cluster secondary ion mass spectrometry and the temperature dependence of molecular depth profiles.

Mao D, Wucher A, Brenes DA, Lu C, Winograd N.

Anal Chem. 2012 May 1;84(9):3981-9. doi: 10.1021/ac2032589. Epub 2012 Apr 10.

PMID:
22455606
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41.

Characterizing in situ Glycerophospholipids with SIMS and MALDI Methodologies.

Passarelli MK, Winograd N.

Surf Interface Anal. 2011 Jan;43(1-2):269-271.

PMID:
22190763
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42.

Fluid Flow and Effusive Desorption: Dominant Mechanisms of Energy Dissipation after Energetic Cluster Bombardment of Molecular Solids.

Brenes DA, Postawa Z, Wucher A, Blenkinsopp P, Garrison BJ, Winograd N.

J Phys Chem Lett. 2011 Jul 22;2(16):2009-2014.

PMID:
21860689
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43.

Molecular depth profiling by wedged crater beveling.

Mao D, Lu C, Winograd N, Wucher A.

Anal Chem. 2011 Aug 15;83(16):6410-7. doi: 10.1021/ac201502w. Epub 2011 Jul 26.

PMID:
21744861
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44.

Lipid imaging with time-of-flight secondary ion mass spectrometry (ToF-SIMS).

Passarelli MK, Winograd N.

Biochim Biophys Acta. 2011 Nov;1811(11):976-90. doi: 10.1016/j.bbalip.2011.05.007. Epub 2011 May 27. Review.

PMID:
21664291
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45.

Label free biochemical 2D and 3D imaging using secondary ion mass spectrometry.

Fletcher JS, Vickerman JC, Winograd N.

Curr Opin Chem Biol. 2011 Oct;15(5):733-40. doi: 10.1016/j.cbpa.2011.05.016. Epub 2011 Jun 12. Review.

PMID:
21664172
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46.

Retrospective sputter depth profiling using 3D mass spectral imaging.

Zheng L, Wucher A, Winograd N.

Surf Interface Anal. 2011 Feb;43(1-2). doi: 10.1002/sia.3509.

PMID:
24347744
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47.

Ionization effects in molecular depth profiling of trehalose films using buckminsterfullerene (C60) cluster ions.

Lu C, Wucher A, Winograd N.

Surf Interface Anal. 2011 Feb;43(1-2). doi: 10.1002/sia.3449.

PMID:
24347742
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48.

Investigating the Fundamentals of Molecular Depth Profiling Using Strong-field Photoionization of Sputtered Neutrals.

Willingham D, Brenes DA, Winograd N, Wucher A.

Surf Interface Anal. 2011 Jan-Feb;43(1-2):45-48.

PMID:
26269660
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49.

Temperature effects in the sputtering of a molecular solid by energetic atomic and cluster projectiles.

Brenes DA, Willingham D, Winograd N, Postawa Z.

Surf Interface Anal. 2011 Jan;43(1-2). doi: 10.1002/sia.3505.

PMID:
24347745
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50.

Fundamental studies of molecular depth profiling using organic delta layers as model systems.

Lu C, Wucher A, Winograd N.

Surf Interface Anal. 2011 Jan;43(1-2). doi: 10.1002/sia.3409.

PMID:
24347743
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