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Items: 1 to 50 of 140

1.

A Pilot Survey of Potentially Hazardous Trace Elements in the Aquatic Environment Near a Coastal Coal-Fired Power Plant in Taiwan.

Kok VC, Winn PR, Hsieh YJ, Chien JW, Yang JM, Yeh GP.

Environ Health Insights. 2019 Jul 19;13:1178630219862236. doi: 10.1177/1178630219862236. eCollection 2019.

2.

Structure, function and dynamics in acyl carrier proteins.

Farmer R, Thomas CM, Winn PJ.

PLoS One. 2019 Jul 10;14(7):e0219435. doi: 10.1371/journal.pone.0219435. eCollection 2019.

3.

Structure of SPH (self-incompatibility protein homologue) proteins: a widespread family of small, highly stable, secreted proteins.

Rajasekar KV, Ji S, Coulthard RJ, Ride JP, Reynolds GL, Winn PJ, Wheeler MJ, Hyde EI, Smith LJ.

Biochem J. 2019 Mar 12;476(5):809-826. doi: 10.1042/BCJ20180828.

PMID:
30782970
4.

Defining the genes for the final steps in biosynthesis of the complex polyketide antibiotic mupirocin by Pseudomonas fluorescens NCIMB10586.

Connolly JA, Wilson A, Macioszek M, Song Z, Wang L, Mohammad HH, Yadav M, di Martino M, Miller CE, Hothersall J, Haines AS, Stephens ER, Crump MP, Willis CL, Simpson TJ, Winn PJ, Thomas CM.

Sci Rep. 2019 Feb 7;9(1):1542. doi: 10.1038/s41598-018-38038-9.

5.

DeepCDpred: Inter-residue distance and contact prediction for improved prediction of protein structure.

Ji S, Oruç T, Mead L, Rehman MF, Thomas CM, Butterworth S, Winn PJ.

PLoS One. 2019 Jan 8;14(1):e0205214. doi: 10.1371/journal.pone.0205214. eCollection 2019.

6.

Prenatal counseling and parental decision-making following a fetal diagnosis of trisomy 13 or 18.

Winn P, Acharya K, Peterson E, Leuthner S.

J Perinatol. 2018 Jul;38(7):788-796. doi: 10.1038/s41372-018-0107-x. Epub 2018 May 8.

PMID:
29740195
7.

Fine Tuning of Antibiotic Activity by a Tailoring Hydroxylase in a Trans-AT Polyketide Synthase Pathway.

Mohammad HH, Connolly JA, Song Z, Hothersall J, Race PR, Willis CL, Simpson TJ, Winn PJ, Thomas CM.

Chembiochem. 2018 Apr 16;19(8):836-841. doi: 10.1002/cbic.201800036. Epub 2018 Mar 13.

PMID:
29363252
8.

A human microglia-like cellular model for assessing the effects of neurodegenerative disease gene variants.

Ryan KJ, White CC, Patel K, Xu J, Olah M, Replogle JM, Frangieh M, Cimpean M, Winn P, McHenry A, Kaskow BJ, Chan G, Cuerdon N, Bennett DA, Boyd JD, Imitola J, Elyaman W, De Jager PL, Bradshaw EM.

Sci Transl Med. 2017 Dec 20;9(421). pii: eaai7635. doi: 10.1126/scitranslmed.aai7635.

9.

Selected Mutations Reveal New Intermediates in the Biosynthesis of Mupirocin and the Thiomarinol Antibiotics.

Gao SS, Wang L, Song Z, Hothersall J, Stevens ER, Connolly J, Winn PJ, Cox RJ, Crump MP, Race PR, Thomas CM, Simpson TJ, Willis CL.

Angew Chem Int Ed Engl. 2017 Mar 27;56(14):3930-3934. doi: 10.1002/anie.201611590. Epub 2017 Feb 9.

PMID:
28181382
10.

Qualitative Evaluation of a Practice-based Experience Pilot Program for Master of Pharmacy Students in Scotland.

Hendry G, Winn P, Wiggins S, Turner CJ.

Am J Pharm Educ. 2016 Dec 25;80(10):165. doi: 10.5688/ajpe8010165.

11.

Description and Evaluation of an MPharm Practice-based Experience Pilot Program.

Winn P, Turner CJ.

Am J Pharm Educ. 2016 Nov 25;80(9):151. doi: 10.5688/ajpe809151.

12.

The Cellular Diversity of the Pedunculopontine Nucleus: Relevance to Behavior in Health and Aspects of Parkinson's Disease.

Pienaar IS, Vernon A, Winn P.

Neuroscientist. 2017 Aug;23(4):415-431. doi: 10.1177/1073858416682471. Epub 2016 Dec 7. Review.

13.

Trans-pQTL study identifies immune crosstalk between Parkinson and Alzheimer loci.

Chan G, White CC, Winn PA, Cimpean M, Replogle JM, Glick LR, Cuerdon NE, Ryan KJ, Johnson KA, Schneider JA, Bennett DA, Chibnik LB, Sperling RA, De Jager PL, Bradshaw EM.

Neurol Genet. 2016 Jul 26;2(4):e90. doi: 10.1212/NXG.0000000000000090. eCollection 2016 Aug.

14.

The pedunculopontine tegmental nucleus-A functional hypothesis from the comparative literature.

Gut NK, Winn P.

Mov Disord. 2016 May;31(5):615-24. doi: 10.1002/mds.26556. Epub 2016 Feb 16. Review.

15.

Genes and Environment in Multiple Sclerosis project: A platform to investigate multiple sclerosis risk.

Xia Z, White CC, Owen EK, Von Korff A, Clarkson SR, McCabe CA, Cimpean M, Winn PA, Hoesing A, Steele SU, Cortese IC, Chitnis T, Weiner HL, Reich DS, Chibnik LB, De Jager PL.

Ann Neurol. 2016 Feb;79(2):178-89. doi: 10.1002/ana.24560. Epub 2015 Dec 9.

16.

CD33 modulates TREM2: convergence of Alzheimer loci.

Chan G, White CC, Winn PA, Cimpean M, Replogle JM, Glick LR, Cuerdon NE, Ryan KJ, Johnson KA, Schneider JA, Bennett DA, Chibnik LB, Sperling RA, Bradshaw EM, De Jager PL.

Nat Neurosci. 2015 Nov;18(11):1556-8. doi: 10.1038/nn.4126. Epub 2015 Sep 28.

17.

Deep brain stimulation of different pedunculopontine targets in a novel rodent model of parkinsonism.

Gut NK, Winn P.

J Neurosci. 2015 Mar 25;35(12):4792-803. doi: 10.1523/JNEUROSCI.3646-14.2015.

18.
19.

Selective lesions of the cholinergic neurons within the posterior pedunculopontine do not alter operant learning or nicotine sensitization.

MacLaren DA, Wilson DI, Winn P.

Brain Struct Funct. 2016 Apr;221(3):1481-97. doi: 10.1007/s00429-014-0985-4. Epub 2015 Jan 14.

20.

A TREM1 variant alters the accumulation of Alzheimer-related amyloid pathology.

Replogle JM, Chan G, White CC, Raj T, Winn PA, Evans DA, Sperling RA, Chibnik LB, Bradshaw EM, Schneider JA, Bennett DA, De Jager PL.

Ann Neurol. 2015 Mar;77(3):469-77. doi: 10.1002/ana.24337.

21.

Characterization of mutations in the PAS domain of the EvgS sensor kinase selected by laboratory evolution for acid resistance in Escherichia coli.

Johnson MD, Bell J, Clarke K, Chandler R, Pathak P, Xia Y, Marshall RL, Weinstock GM, Loman NJ, Winn PJ, Lund PA.

Mol Microbiol. 2014 Sep;93(5):911-27. doi: 10.1111/mmi.12704. Epub 2014 Jul 24.

22.

Selective AKR1C3 inhibitors do not recapitulate the anti-leukaemic activities of the pan-AKR1C inhibitor medroxyprogesterone acetate.

Khanim F, Davies N, Veliça P, Hayden R, Ride J, Pararasa C, Chong MG, Gunther U, Veerapen N, Winn P, Farmer R, Trivier E, Rigoreau L, Drayson M, Bunce C.

Br J Cancer. 2014 Mar 18;110(6):1506-16. doi: 10.1038/bjc.2014.83. Epub 2014 Feb 25.

23.

The roles of the nucleus accumbens core, dorsomedial striatum, and dorsolateral striatum in learning: performance and extinction of Pavlovian fear-conditioned responses and instrumental avoidance responses.

Wendler E, Gaspar JC, Ferreira TL, Barbiero JK, Andreatini R, Vital MA, Blaha CD, Winn P, Da Cunha C.

Neurobiol Learn Mem. 2014 Mar;109:27-36. doi: 10.1016/j.nlm.2013.11.009. Epub 2013 Nov 26.

24.

A conserved motif flags acyl carrier proteins for β-branching in polyketide synthesis.

Haines AS, Dong X, Song Z, Farmer R, Williams C, Hothersall J, Płoskoń E, Wattana-Amorn P, Stephens ER, Yamada E, Gurney R, Takebayashi Y, Masschelein J, Cox RJ, Lavigne R, Willis CL, Simpson TJ, Crosby J, Winn PJ, Thomas CM, Crump MP.

Nat Chem Biol. 2013 Nov;9(11):685-692. doi: 10.1038/nchembio.1342. Epub 2013 Sep 22.

25.

Updating of action-outcome associations is prevented by inactivation of the posterior pedunculopontine tegmental nucleus.

Maclaren DA, Wilson DI, Winn P.

Neurobiol Learn Mem. 2013 May;102:28-33. doi: 10.1016/j.nlm.2013.03.002. Epub 2013 Apr 6.

26.

The radical ion chemistry of S-nitrosylated peptides.

Jones AW, Winn PJ, Cooper HJ.

J Am Soc Mass Spectrom. 2012 Dec;23(12):2063-74. doi: 10.1007/s13361-012-0492-x. Epub 2012 Oct 4.

PMID:
23055078
27.

ARABIDILLO gene homologues in basal land plants: species-specific gene duplication and likely functional redundancy.

Moody LA, Saidi Y, Smiles EJ, Bradshaw SJ, Meddings M, Winn PJ, Coates JC.

Planta. 2012 Dec;236(6):1927-41. doi: 10.1007/s00425-012-1742-7. Epub 2012 Sep 4.

PMID:
22945313
28.

Evidence that conditioned avoidance responses are reinforced by positive prediction errors signaled by tonic striatal dopamine.

Dombrowski PA, Maia TV, Boschen SL, Bortolanza M, Wendler E, Schwarting RK, Brandão ML, Winn P, Blaha CD, Da Cunha C.

Behav Brain Res. 2013 Mar 15;241:112-9. doi: 10.1016/j.bbr.2012.06.031. Epub 2012 Jul 3.

PMID:
22771418
29.

Multiple, ligand-dependent routes from the active site of cytochrome P450 2C9.

Cojocaru V, Winn PJ, Wade RC.

Curr Drug Metab. 2012 Feb;13(2):143-54.

PMID:
22208529
30.

Nicotine self-administered directly into the VTA by rats is weakly reinforcing but has strong reinforcement enhancing properties.

Farquhar MJ, Latimer MP, Winn P.

Psychopharmacology (Berl). 2012 Mar;220(1):43-54. doi: 10.1007/s00213-011-2452-8. Epub 2011 Sep 6.

PMID:
21894487
31.

Roles of D1-like dopamine receptors in the nucleus accumbens and dorsolateral striatum in conditioned avoidance responses.

Wietzikoski EC, Boschen SL, Miyoshi E, Bortolanza M, Dos Santos LM, Frank M, Brandão ML, Winn P, Da Cunha C.

Psychopharmacology (Berl). 2012 Jan;219(1):159-69. doi: 10.1007/s00213-011-2384-3. Epub 2011 Jul 1.

PMID:
21720753
32.

The role of nucleus accumbens and dorsolateral striatal D2 receptors in active avoidance conditioning.

Boschen SL, Wietzikoski EC, Winn P, Da Cunha C.

Neurobiol Learn Mem. 2011 Sep;96(2):254-62. doi: 10.1016/j.nlm.2011.05.002. Epub 2011 May 17.

33.

Functional disconnection of the substantia nigra pars compacta from the pedunculopontine nucleus impairs learning of a conditioned avoidance task.

Bortolanza M, Wietzikoski EC, Boschen SL, Dombrowski PA, Latimer M, Maclaren DA, Winn P, Da Cunha C.

Neurobiol Learn Mem. 2010 Sep;94(2):229-39. doi: 10.1016/j.nlm.2010.05.011. Epub 2010 Jun 1.

34.

ProMetCS: An Atomistic Force Field for Modeling Protein-Metal Surface Interactions in a Continuum Aqueous Solvent.

Kokh DB, Corni S, Winn PJ, Hoefling M, Gottschalk KE, Wade RC.

J Chem Theory Comput. 2010 May 11;6(5):1753-68. doi: 10.1021/ct100086j. Epub 2010 Apr 16.

PMID:
26615704
35.
36.

Bar pressing for food: differential consequences of lesions to the anterior versus posterior pedunculopontine.

Wilson DI, MacLaren DA, Winn P.

Eur J Neurosci. 2009 Aug;30(3):504-13. doi: 10.1111/j.1460-9568.2009.06836.x. Epub 2009 Jul 15.

PMID:
19614747
37.

Experimental studies of pedunculopontine functions: are they motor, sensory or integrative?

Winn P.

Parkinsonism Relat Disord. 2008;14 Suppl 2:S194-8. doi: 10.1016/j.parkreldis.2008.04.030. Epub 2008 Jun 27. Review.

PMID:
18585079
38.

Cholinergic modulation of midbrain dopaminergic systems.

Mena-Segovia J, Winn P, Bolam JP.

Brain Res Rev. 2008 Aug;58(2):265-71. doi: 10.1016/j.brainresrev.2008.02.003. Epub 2008 Feb 21. Review.

PMID:
18343506
39.

A functional dissociation of the anterior and posterior pedunculopontine tegmental nucleus: excitotoxic lesions have differential effects on locomotion and the response to nicotine.

Alderson HL, Latimer MP, Winn P.

Brain Struct Funct. 2008 Sep;213(1-2):247-53. doi: 10.1007/s00429-008-0174-4. Epub 2008 Feb 12.

40.

The pedunculopontine tegmental nucleus and the nucleus basalis magnocellularis: do both have a role in sustained attention?

Rostron CL, Farquhar MJ, Latimer MP, Winn P.

BMC Neurosci. 2008 Jan 30;9:16. doi: 10.1186/1471-2202-9-16.

41.

Protein-protein docking by simulating the process of association subject to biochemical constraints.

Motiejunas D, Gabdoulline R, Wang T, Feldman-Salit A, Johann T, Winn PJ, Wade RC.

Proteins. 2008 Jun;71(4):1955-69. doi: 10.1002/prot.21867.

PMID:
18186463
42.

An assessment of the contributions of the pedunculopontine tegmental and cuneiform nuclei to anxiety and neophobia.

Walker SC, Winn P.

Neuroscience. 2007 Dec 5;150(2):273-90. Epub 2007 Sep 14.

PMID:
17951012
43.

Structural and electrostatic properties of ubiquitination and related pathways.

Winn PJ, Zahran M, Battey JN, Zhou Y, Wade RC, Banerjee A.

Front Biosci. 2007 May 1;12:3419-30. Review.

PMID:
17485310
44.

Fusion of diphtheria toxin and urotensin II produces a neurotoxin selective for cholinergic neurons in the rat mesopontine tegmentum.

Clark SD, Alderson HL, Winn P, Latimer MP, Nothacker HP, Civelli O.

J Neurochem. 2007 Jul;102(1):112-20. Epub 2007 Apr 10.

45.

The ins and outs of cytochrome P450s.

Cojocaru V, Winn PJ, Wade RC.

Biochim Biophys Acta. 2007 Mar;1770(3):390-401. Epub 2006 Jul 21. Review.

PMID:
16920266
46.

The pedunculopontine tegmental nucleus and responding for sucrose reward.

Ainge JA, Keating GL, Latimer MP, Winn P.

Behav Neurosci. 2006 Jun;120(3):563-70.

PMID:
16768608
47.
48.

Classical polarization in hybrid QM/MM methods.

Illingworth CJ, Gooding SR, Winn PJ, Jones GA, Ferenczy GG, Reynolds CA.

J Phys Chem A. 2006 May 25;110(20):6487-97.

PMID:
16706406
49.
50.

The Humber Estuary, Eastern England: Strategic planning of flood defences and habitats.

Edwards AM, Winn PS.

Mar Pollut Bull. 2006;53(1-4):165-74. Epub 2006 Jan 25.

PMID:
16442132

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