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Changes in immunosuppressive treatment of chronic graft-versus-host disease - comparison of 2 surveys within allogeneic hematopoietic stem cell transplant centers in Germany, Austria and Switzerland.

Wolff D, Hilgendorf I, Wagner-Drouet E, Jedlickova Z, Ayuk F, Zeiser R, Schäfer-Eckart K, Gerbitz A, Stadler M, Klein S, Middeke JM, Lawitschka A, Winkler J, Halter J, Holler E, Kobbe G, Stelljes M, Ditschkowski M, Greinix H.

Biol Blood Marrow Transplant. 2019 Mar 12. pii: S1083-8791(19)30154-5. doi: 10.1016/j.bbmt.2019.03.003. [Epub ahead of print]


Repeatability and Optimization of FDG Positron Emission Tomography for Evaluation of Cardiac Sarcoidosis.

Alvi RM, Young BD, Shahab Z, Pan H, Winkler J, Herzog E, Miller EJ.

JACC Cardiovasc Imaging. 2019 Feb 16. pii: S1936-878X(19)30109-3. doi: 10.1016/j.jcmg.2019.01.011. [Epub ahead of print] No abstract available.


Covalent Fluorophore Labeling of Oligonucleotides and Generation of Other Oligonucleotide Bioconjugates.

Lorenzer C, Winkler J.

Methods Mol Biol. 2019;1943:61-72. doi: 10.1007/978-1-4939-9092-4_4.


Survival benefit in bariatric surgery kidney recipients may be mediated through effects on kidney graft function and improvement of co-morbidities: A case-control study.

Schindel H, Winkler J, Yemini R, Carmeli I, Nesher E, Keidar A.

Surg Obes Relat Dis. 2019 Feb 15. pii: S1550-7289(19)30044-9. doi: 10.1016/j.soard.2019.01.034. [Epub ahead of print]


Retikuläre Hyperpigmentierungen an Rumpf und Beugen bei einem 16-jährigen Jungen.

Winkler JK, Enk AH, Haenssle HA, Toberer F.

J Dtsch Dermatol Ges. 2019 Feb;17(2):201-204. doi: 10.1111/ddg.13738_g. No abstract available.


Involvement of the Adhesion GPCRs Latrophilins in the Regulation of Insulin Release.

Röthe J, Thor D, Winkler J, Knierim AB, Binder C, Huth S, Kraft R, Rothemund S, Schöneberg T, Prömel S.

Cell Rep. 2019 Feb 5;26(6):1573-1584.e5. doi: 10.1016/j.celrep.2019.01.040.


DCX-Related Disorders.

Hehr U, Uyanik G, Aigner L, Couillard-Despres S, Winkler J.

In: Adam MP, Ardinger HH, Pagon RA, Wallace SE, Bean LJH, Stephens K, Amemiya A, editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993-2019.
2007 Oct 19 [updated 2019 Feb 7].


Exploring gait adaptations to perturbed and conventional treadmill training in Parkinson's disease: Time-course, sustainability, and transfer.

Steib S, Klamroth S, Gaßner H, Pasluosta C, Eskofier B, Winkler J, Klucken J, Pfeifer K.

Hum Mov Sci. 2019 Jan 31;64:123-132. doi: 10.1016/j.humov.2019.01.007. [Epub ahead of print]


Two Tryptophans Are Better Than One in Accelerating Electron Flow through a Protein.

Takematsu K, Williamson HR, Nikolovski P, Kaiser JT, Sheng Y, Pospíšil P, Towrie M, Heyda J, Hollas D, Záliš S, Gray HB, Vlček A, Winkler JR.

ACS Cent Sci. 2019 Jan 23;5(1):192-200. doi: 10.1021/acscentsci.8b00882. Epub 2019 Jan 7.


Extracellular aggregated alpha synuclein primarily triggers lysosomal dysfunction in neural cells prevented by trehalose.

Hoffmann AC, Minakaki G, Menges S, Salvi R, Savitskiy S, Kazman A, Vicente Miranda H, Mielenz D, Klucken J, Winkler J, Xiang W.

Sci Rep. 2019 Jan 24;9(1):544. doi: 10.1038/s41598-018-35811-8.


Hole Hopping Across a Protein-Protein Interface.

Takematsu K, Pospíšil P, Pižl M, Towrie M, Heyda J, Záliš S, Kaiser JT, Winkler JR, Gray HB, Vlček A.

J Phys Chem B. 2019 Feb 21;123(7):1578-1591. doi: 10.1021/acs.jpcb.8b11982. Epub 2019 Feb 6.


Transcriptional Alterations by Ischaemic Postconditioning in a Pig Infarction Model: Impact on Microvascular Protection.

Lukovic D, Gugerell A, Zlabinger K, Winkler J, Pavo N, Baranyai T, Giricz Z, Varga ZV, Riesenhuber M, Spannbauer A, Traxler D, Jakab A, Garamvölgyi R, Petnehazy Ö, Pils D, Tóth L, Schulz R, Ferdinandy P, Gyöngyösi M.

Int J Mol Sci. 2019 Jan 15;20(2). pii: E344. doi: 10.3390/ijms20020344.


A 3-(4-nitronaphthen-1-yl) amino-benzoate analog as a bifunctional AKR1C3 inhibitor and AR antagonist: Head to head comparison with other advanced AKR1C3 targeted therapeutics.

Wangtrakuldee P, Adeniji AO, Zang T, Duan L, Khatri B, Twenter BM, Estrada MA, Higgins TF, Winkler JD, Penning TM.

J Steroid Biochem Mol Biol. 2019 Jan 11. pii: S0960-0760(18)30720-9. doi: 10.1016/j.jsbmb.2019.01.001. [Epub ahead of print]


Treadmill exercise intervention improves gait and postural control in alpha-synuclein mouse models without inducing cerebral autophagy.

Minakaki G, Canneva F, Chevessier F, Bode F, Menges S, Timotius IK, Kalinichenko LS, Meixner H, Müller CP, Eskofier BM, Casadei N, Riess O, Schröder R, Winkler J, Xiang W, von Hörsten S, Klucken J.

Behav Brain Res. 2019 May 2;363:199-215. doi: 10.1016/j.bbr.2018.11.035. Epub 2018 Dec 30.


Reticular hyperpigmentation on the trunk and flexures of the extremities in a 16-year-old boy.

Winkler JK, Enk AH, Haenssle HA, Toberer F.

J Dtsch Dermatol Ges. 2019 Feb;17(2):201-204. doi: 10.1111/ddg.13738. Epub 2018 Dec 28. No abstract available.


Tideglusib Rescues Neurite Pathology of SPG11 iPSC Derived Cortical Neurons.

Pozner T, Schray A, Regensburger M, Lie DC, Schlötzer-Schrehardt U, Winkler J, Turan S, Winner B.

Front Neurosci. 2018 Dec 6;12:914. doi: 10.3389/fnins.2018.00914. eCollection 2018.


Volatilomics: a non-invasive technique for screening plant phenotypic traits.

Jud W, Winkler JB, Niederbacher B, Niederbacher S, Schnitzler JP.

Plant Methods. 2018 Dec 18;14:109. doi: 10.1186/s13007-018-0378-4. eCollection 2018.


[The Influence of Residence Status on Psychiatric Symptom Load of Asylum Seekers in Germany].

Winkler JG, Brandl EJ, Bretz HJ, Heinz A, Schouler-Ocak M.

Psychiatr Prax. 2018 Dec 12. doi: 10.1055/a-0806-3568. [Epub ahead of print] German.


Room-Temperature Strong Coupling of CdSe Nanoplatelets and Plasmonic Hole Arrays.

Winkler JM, Rabouw FT, Rossinelli A, Jayanti S, McPeak KM, Kim DK, le Feber B, Prins F, Norris DJ.

Nano Lett. 2018 Dec 5. doi: 10.1021/acs.nanolett.8b03422. [Epub ahead of print]


Human SPG11 cerebral organoids reveal cortical neurogenesis impairment.

Pérez-Brangulí F, Buchsbaum IY, Pozner T, Regensburger M, Fan W, Schray A, Börstler T, Mishra H, Gräf D, Kohl Z, Winkler J, Berninger B, Cappello S, Winner B.

Hum Mol Genet. 2018 Nov 22. doi: 10.1093/hmg/ddy397. [Epub ahead of print]


Need for high-resolution Genetic Analysis in iPSC: Results and Lessons from the ForIPS Consortium.

Popp B, Krumbiegel M, Grosch J, Sommer A, Uebe S, Kohl Z, Plötz S, Farrell M, Trautmann U, Kraus C, Ekici AB, Asadollahi R, Regensburger M, Günther K, Rauch A, Edenhofer F, Winkler J, Winner B, Reis A.

Sci Rep. 2018 Nov 21;8(1):17201. doi: 10.1038/s41598-018-35506-0.


Zooming in on Cryopreservation of hiPSCs and Neural Derivatives: A Dual-Center Study Using Adherent Vitrification.

Kaindl J, Meiser I, Majer J, Sommer A, Krach F, Katsen-Globa A, Winkler J, Zimmermann H, Neubauer JC, Winner B.

Stem Cells Transl Med. 2019 Mar;8(3):247-259. doi: 10.1002/sctm.18-0121. Epub 2018 Nov 19.


Oligodendroglial α-synucleinopathy-driven neuroinflammation in multiple system atrophy.

Hoffmann A, Ettle B, Battis K, Reiprich S, Schlachetzki JCM, Masliah E, Wegner M, Kuhlmann T, Riemenschneider MJ, Winkler J.

Brain Pathol. 2018 Nov 16. doi: 10.1111/bpa.12678. [Epub ahead of print]


PPT1 Promotes Tumor Growth and Is the Molecular Target of Chloroquine Derivatives in Cancer.

Rebecca VW, Nicastri MC, Fennelly C, Chude CI, Barber-Rotenberg JS, Ronghe A, McAfee Q, McLaughlin NP, Zhang G, Goldman AR, Ojha R, Piao S, Noguera-Ortega E, Martorella A, Alicea GM, Lee JJ, Schuchter LM, Xu X, Herlyn M, Marmorstein R, Gimotty PA, Speicher DW, Winkler JD, Amaravadi RK.

Cancer Discov. 2019 Feb;9(2):220-229. doi: 10.1158/2159-8290.CD-18-0706. Epub 2018 Nov 15.


Tracheal Sounds Features Changes in Different Sleep Stages Based on Complex Wavelet Analysis.

Soltanzadeh R, Winkler J, Shafai C.

Conf Proc IEEE Eng Med Biol Soc. 2018 Jul;2018:421-424. doi: 10.1109/EMBC.2018.8512446.


A Comprehensive Mutagenesis Screen of the Adhesion GPCR Latrophilin-1/ADGRL1.

Nazarko O, Kibrom A, Winkler J, Leon K, Stoveken H, Salzman G, Merdas K, Lu Y, Narkhede P, Tall G, Prömel S, Araç D.

iScience. 2018 May 25;3:264-278. doi: 10.1016/j.isci.2018.04.019. Epub 2018 Apr 30.


Population Pharmacokinetics of Adjunctive Lacosamide in Pediatric Patients With Epilepsy.

Winkler J, Schoemaker R, Stockis A.

J Clin Pharmacol. 2019 Apr;59(4):541-547. doi: 10.1002/jcph.1340. Epub 2018 Nov 14.


Modeling and simulation for the evaluation of dose adaptation rules of intravenous lacosamide in children.

Winkler J, Schoemaker R, Stockis A.

Epilepsy Res. 2019 Jan;149:13-16. doi: 10.1016/j.eplepsyres.2018.10.011. Epub 2018 Oct 26.


A Single Bout of Aerobic Exercise Improves Motor Skill Consolidation in Parkinson's Disease.

Steib S, Wanner P, Adler W, Winkler J, Klucken J, Pfeifer K.

Front Aging Neurosci. 2018 Oct 22;10:328. doi: 10.3389/fnagi.2018.00328. eCollection 2018.


Abrogating Native α-Synuclein Tetramers in Mice Causes a L-DOPA-Responsive Motor Syndrome Closely Resembling Parkinson's Disease.

Nuber S, Rajsombath M, Minakaki G, Winkler J, Müller CP, Ericsson M, Caldarone B, Dettmer U, Selkoe DJ.

Neuron. 2018 Oct 10;100(1):75-90.e5. doi: 10.1016/j.neuron.2018.09.014.


Therapeutic Potential of Fulvic Acid in Chronic Inflammatory Diseases and Diabetes.

Winkler J, Ghosh S.

J Diabetes Res. 2018 Sep 10;2018:5391014. doi: 10.1155/2018/5391014. eCollection 2018. Review.


Arabidopsis RUP2 represses UVR8-mediated flowering in noninductive photoperiods.

Arongaus AB, Chen S, Pireyre M, Glöckner N, Galvão VC, Albert A, Winkler JB, Fankhauser C, Harter K, Ulm R.

Genes Dev. 2018 Oct 1;32(19-20):1332-1343. doi: 10.1101/gad.318592.118. Epub 2018 Sep 25.


Public Health England's sugar reduction programme did not "fail".

Winkler J.

BMJ. 2018 Sep 20;362:k3531. doi: 10.1136/bmj.k3531. No abstract available.


Sensor-based gait analysis of individualized improvement during apomorphine titration in Parkinson's disease.

Marxreiter F, Gaßner H, Borozdina O, Barth J, Kohl Z, Schlachetzki JCM, Thun-Hohenstein C, Volc D, Eskofier BM, Winkler J, Klucken J.

J Neurol. 2018 Nov;265(11):2656-2665. doi: 10.1007/s00415-018-9012-7. Epub 2018 Sep 8.


Targeting quiescent leukemic stem cells using second generation autophagy inhibitors.

Baquero P, Dawson A, Mukhopadhyay A, Kuntz EM, Mitchell R, Olivares O, Ianniciello A, Scott MT, Dunn K, Nicastri MC, Winkler JD, Michie AM, Ryan KM, Halsey C, Gottlieb E, Keaney EP, Murphy LO, Amaravadi RK, Holyoake TL, Helgason GV.

Leukemia. 2018 Sep 5. doi: 10.1038/s41375-018-0252-4. [Epub ahead of print]


Alveolar Macrophages Provide an Early Mycobacterium tuberculosis Niche and Initiate Dissemination.

Cohen SB, Gern BH, Delahaye JL, Adams KN, Plumlee CR, Winkler JK, Sherman DR, Gerner MY, Urdahl KB.

Cell Host Microbe. 2018 Sep 12;24(3):439-446.e4. doi: 10.1016/j.chom.2018.08.001. Epub 2018 Aug 23.


Correction to: Glucuronidation of deoxynivalenol (DON) by different animal species: identification of iso-DON glucuronides and iso-deepoxy-DON glucuronides as novel DON metabolites in pigs, rats, mice, and cows.

Schwartz-Zimmermann HE, Hametner C, Nagl V, Fiby I, Macheiner L, Winkler J, Dänicke S, Clark E, Pestka JJ, Berthiller F.

Arch Toxicol. 2018 Oct;92(10):3245-3246. doi: 10.1007/s00204-018-2273-1.


Physiological responses of date palm (Phoenix dactylifera) seedlings to acute ozone exposure at high temperature.

Du B, Kreuzwieser J, Winkler JB, Ghirardo A, Schnitzler JP, Ache P, Alfarraj S, Hedrich R, White P, Rennenberg H.

Environ Pollut. 2018 Nov;242(Pt A):905-913. doi: 10.1016/j.envpol.2018.07.059. Epub 2018 Jul 18.


Design, Synthesis, and Biological Evaluation of Allosteric Effectors That Enhance CO Release from Carboxyhemoglobin.

Goldstein SR, Liu C, Safo MK, Nakagawa A, Zapol WM, Winkler JD.

ACS Med Chem Lett. 2018 May 11;9(7):714-718. doi: 10.1021/acsmedchemlett.8b00166. eCollection 2018 Jul 12.


Multiplex navigation of global regulatory networks (MINR) in yeast for improved ethanol tolerance and production.

Liu R, Liang L, Choudhury A, Garst AD, Eckert CA, Oh EJ, Winkler J, Gill RT.

Metab Eng. 2019 Jan;51:50-58. doi: 10.1016/j.ymben.2018.07.007. Epub 2018 Jul 17.


A monocyte gene expression signature in the early clinical course of Parkinson's disease.

Schlachetzki JCM, Prots I, Tao J, Chun HB, Saijo K, Gosselin D, Winner B, Glass CK, Winkler J.

Sci Rep. 2018 Jul 17;8(1):10757. doi: 10.1038/s41598-018-28986-7.


Living with Oxygen.

Gray HB, Winkler JR.

Acc Chem Res. 2018 Aug 21;51(8):1850-1857. doi: 10.1021/acs.accounts.8b00245. Epub 2018 Jul 17.


α-Synuclein oligomers induce early axonal dysfunction in human iPSC-based models of synucleinopathies.

Prots I, Grosch J, Brazdis RM, Simmnacher K, Veber V, Havlicek S, Hannappel C, Krach F, Krumbiegel M, Schütz O, Reis A, Wrasidlo W, Galasko DR, Groemer TW, Masliah E, Schlötzer-Schrehardt U, Xiang W, Winkler J, Winner B.

Proc Natl Acad Sci U S A. 2018 Jul 24;115(30):7813-7818. doi: 10.1073/pnas.1713129115. Epub 2018 Jul 10.


Sporadic Parkinson's disease derived neuronal cells show disease-specific mRNA and small RNA signatures with abundant deregulation of piRNAs.

Schulze M, Sommer A, Plötz S, Farrell M, Winner B, Grosch J, Winkler J, Riemenschneider MJ.

Acta Neuropathol Commun. 2018 Jul 10;6(1):58. doi: 10.1186/s40478-018-0561-x.


Th17 Lymphocytes Induce Neuronal Cell Death in a Human iPSC-Based Model of Parkinson's Disease.

Sommer A, Maxreiter F, Krach F, Fadler T, Grosch J, Maroni M, Graef D, Eberhardt E, Riemenschneider MJ, Yeo GW, Kohl Z, Xiang W, Gage FH, Winkler J, Prots I, Winner B.

Cell Stem Cell. 2018 Jul 5;23(1):123-131.e6. doi: 10.1016/j.stem.2018.06.015.


Serotonin 1A receptor density measured by F18-Mefway PET/CT in mesiotemporal cortex and raphe does not discriminate therapeutic response in patients with major depressive episode.

Barth M, Dunzinger A, Wimmer I, Winkler J, Rittmannsberger H, Nader M, Pichler R.

Q J Nucl Med Mol Imaging. 2018 Jun 14. doi: 10.23736/S1824-4785.18.03039-X. [Epub ahead of print]


Dynamic footprints of α-synucleinopathic mice recorded by CatWalk gait analysis.

Timotius IK, Canneva F, Minakaki G, Pasluosta C, Moceri S, Casadei N, Riess O, Winkler J, Klucken J, von Hörsten S, Eskofier B.

Data Brief. 2018 Jan 3;17:189-193. doi: 10.1016/j.dib.2017.12.067. eCollection 2018 Apr.


Longitudinal studies of the 18F-FDG kinetics after ipilimumab treatment in metastatic melanoma patients based on dynamic FDG PET/CT.

Sachpekidis C, Anwar H, Winkler JK, Kopp-Schneider A, Larribere L, Haberkorn U, Hassel JC, Dimitrakopoulou-Strauss A.

Cancer Immunol Immunother. 2018 Aug;67(8):1261-1270. doi: 10.1007/s00262-018-2183-3. Epub 2018 Jun 5.


Mitochondrial Aging Defects Emerge in Directly Reprogrammed Human Neurons due to Their Metabolic Profile.

Kim Y, Zheng X, Ansari Z, Bunnell MC, Herdy JR, Traxler L, Lee H, Paquola ACM, Blithikioti C, Ku M, Schlachetzki JCM, Winkler J, Edenhofer F, Glass CK, Paucar AA, Jaeger BN, Pham S, Boyer L, Campbell BC, Hunter T, Mertens J, Gage FH.

Cell Rep. 2018 May 29;23(9):2550-2558. doi: 10.1016/j.celrep.2018.04.105.


Fluctuating hydrogen-bond networks govern anomalous electron transfer kinetics in a blue copper protein.

Kretchmer JS, Boekelheide N, Warren JJ, Winkler JR, Gray HB, Miller TF 3rd.

Proc Natl Acad Sci U S A. 2018 Jun 12;115(24):6129-6134. doi: 10.1073/pnas.1805719115. Epub 2018 May 29.

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