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Items: 1 to 50 of 58

1.

Xanthan gum-based hydrogel containing nanocapsules for cutaneous diphenyl diselenide delivery in melanoma therapy.

Ferreira LM, Sari MHM, Azambuja JH, da Silveira EF, Cervi VF, Marchiori MCL, Maria-Engler SS, Wink MR, Azevedo JG, Nogueira CW, Braganhol E, Cruz L.

Invest New Drugs. 2019 Jul 2. doi: 10.1007/s10637-019-00823-2. [Epub ahead of print]

PMID:
31264068
2.

Dipyridamole impairs autophagic flux and exerts antiproliferative activity on prostate cancer cells.

Thomé MP, Pereira LC, Onzi GR, Rohden F, Ilha M, Guma FT, Wink MR, Lenz G.

Exp Cell Res. 2019 Jun 11. pii: S0014-4827(19)30288-5. doi: 10.1016/j.yexcr.2019.06.001. [Epub ahead of print]

PMID:
31194978
3.

Physical exercise and human adipose-derived mesenchymal stem cells ameliorate motor disturbances in a male rat model of Parkinson's disease.

Cucarián JD, Berrío JP, Rodrigues C, Zancan M, Wink MR, de Oliveira A.

J Neurosci Res. 2019 Sep;97(9):1095-1109. doi: 10.1002/jnr.24442. Epub 2019 May 22.

PMID:
31119788
4.

Characterization of soluble CD39 (SolCD39/NTPDase1) from PiggyBac nonviral system as a tool to control the nucleotides level.

Beckenkamp LR, Iser IC, Onzi GR, Fontoura DMSD, Bertoni APS, Sévigny J, Lenz G, Wink MR.

Biochem J. 2019 Jun 11;476(11):1637-1651. doi: 10.1042/BCJ20190040.

PMID:
31085558
5.

EMT-like process in glioblastomas and reactive astrocytes.

Iser IC, Lenz G, Wink MR.

Neurochem Int. 2019 Jan;122:139-143. doi: 10.1016/j.neuint.2018.11.016. Epub 2018 Nov 26.

PMID:
30496766
6.

Activity of ecto-5'-nucleotidase (NT5E/CD73) is increased in papillary thyroid carcinoma and its expression is associated with metastatic lymph nodes.

Bertoni APS, Bracco PA, de Campos RP, Lutz BS, Assis-Brasil BM, Meyer ELS, Saffi J, Braganhol E, Furlanetto TW, Wink MR.

Mol Cell Endocrinol. 2019 Jan 5;479:54-60. doi: 10.1016/j.mce.2018.08.013. Epub 2018 Sep 2.

PMID:
30184475
7.

CD73 Downregulation Decreases In Vitro and In Vivo Glioblastoma Growth.

Azambuja JH, Gelsleichter NE, Beckenkamp LR, Iser IC, Fernandes MC, Figueiró F, Battastini AMO, Scholl JN, de Oliveira FH, Spanevello RM, Sévigny J, Wink MR, Stefani MA, Teixeira HF, Braganhol E.

Mol Neurobiol. 2019 May;56(5):3260-3279. doi: 10.1007/s12035-018-1240-4. Epub 2018 Aug 16.

PMID:
30117104
8.

Comparison of Human Denuded Amniotic Membrane and Porcine Small Intestine Submucosa as Scaffolds for Limbal Mesenchymal Stem Cells.

Sous Naasani LI, Rodrigues C, Azevedo JG, Damo Souza AF, Buchner S, Wink MR.

Stem Cell Rev. 2018 Oct;14(5):744-754. doi: 10.1007/s12015-018-9819-8.

PMID:
29707747
9.

Extracellular ATP is Differentially Metabolized on Papillary Thyroid Carcinoma Cells Surface in Comparison to Normal Cells.

Bertoni APS, de Campos RP, Tsao M, Braganhol E, Furlanetto TW, Wink MR.

Cancer Microenviron. 2018 Jun;11(1):61-70. doi: 10.1007/s12307-018-0206-4. Epub 2018 Feb 17.

10.

Analysis of NTPDase2 in the cell membrane using fluorescence recovery after photobleaching (FRAP).

Kipper FC, Tamajusuku ASK, Minussi DC, Vargas JE, Battastini AMO, Kaczmarek E, Robson SC, Lenz G, Wink MR.

Cytometry A. 2018 Feb;93(2):232-238. doi: 10.1002/cyto.a.23317. Epub 2018 Jan 24.

11.

Hyperthermia and associated changes in membrane fluidity potentiate P2X7 activation to promote tumor cell death.

de Andrade Mello P, Bian S, Savio LEB, Zhang H, Zhang J, Junger W, Wink MR, Lenz G, Buffon A, Wu Y, Robson SC.

Oncotarget. 2017 Jun 21;8(40):67254-67268. doi: 10.18632/oncotarget.18595. eCollection 2017 Sep 15.

12.

Cervical cancer stem-like cells: systematic review and identification of reference genes for gene expression.

de Campos RP, Schultz IC, de Andrade Mello P, Davies S, Gasparin MS, Bertoni APS, Buffon A, Wink MR.

Cell Biol Int. 2018 Feb;42(2):139-152. doi: 10.1002/cbin.10878. Epub 2017 Nov 9.

PMID:
28949053
13.

Extracellular Nucleotide Hydrolysis in Dermal and Limbal Mesenchymal Stem Cells: A Source of Adenosine Production.

Naasani LIS, Rodrigues C, de Campos RP, Beckenkamp LR, Iser IC, Bertoni APS, Wink MR.

J Cell Biochem. 2017 Aug;118(8):2430-2442. doi: 10.1002/jcb.25909. Epub 2017 Apr 25.

PMID:
28120532
14.

The Epithelial-to-Mesenchymal Transition-Like Process in Glioblastoma: An Updated Systematic Review and In Silico Investigation.

Iser IC, Pereira MB, Lenz G, Wink MR.

Med Res Rev. 2017 Mar;37(2):271-313. doi: 10.1002/med.21408. Epub 2016 Sep 12. Review.

PMID:
27617697
15.

Modulation of Autophagy by Calcium Signalosome in Human Disease.

Filippi-Chiela EC, Viegas MS, Thomé MP, Buffon A, Wink MR, Lenz G.

Mol Pharmacol. 2016 Sep;90(3):371-84. doi: 10.1124/mol.116.105171. Epub 2016 Jul 19. Review.

PMID:
27436127
16.

Analysis of the safety of mesenchymal stromal cells secretome for glioblastoma treatment.

Onzi GR, Ledur PF, Hainzenreder LD, Bertoni AP, Silva AO, Lenz G, Wink MR.

Cytotherapy. 2016 Jul;18(7):828-37. doi: 10.1016/j.jcyt.2016.03.299. Epub 2016 May 17.

PMID:
27210718
17.

Conditioned Medium from Adipose-Derived Stem Cells (ADSCs) Promotes Epithelial-to-Mesenchymal-Like Transition (EMT-Like) in Glioma Cells In vitro.

Iser IC, Ceschini SM, Onzi GR, Bertoni AP, Lenz G, Wink MR.

Mol Neurobiol. 2016 Dec;53(10):7184-7199. Epub 2015 Dec 19.

PMID:
26687184
18.

Identification of valid endogenous control genes for determining gene expression in C6 glioma cell line treated with conditioned medium from adipose-derived stem cell.

Iser IC, de Campos RP, Bertoni AP, Wink MR.

Biomed Pharmacother. 2015 Oct;75:75-82. doi: 10.1016/j.biopha.2015.08.035. Epub 2015 Sep 7. Review.

PMID:
26463634
19.

Differential Expression and Enzymatic Activity of DPPIV/CD26 Affects Migration Ability of Cervical Carcinoma Cells.

Beckenkamp A, Willig JB, Santana DB, Nascimento J, Paccez JD, Zerbini LF, Bruno AN, Pilger DA, Wink MR, Buffon A.

PLoS One. 2015 Jul 29;10(7):e0134305. doi: 10.1371/journal.pone.0134305. eCollection 2015.

20.

Adenosine uptake is the major effector of extracellular ATP toxicity in human cervical cancer cells.

Mello Pde A, Filippi-Chiela EC, Nascimento J, Beckenkamp A, Santana DB, Kipper F, Casali EA, Nejar Bruno A, Paccez JD, Zerbini LF, Wink MR, Lenz G, Buffon A.

Mol Biol Cell. 2014 Oct 1;25(19):2905-18. doi: 10.1091/mbc.E14-01-0042. Epub 2014 Aug 7.

21.

NTPDase5/PCPH as a new target in highly aggressive tumors: a systematic review.

Bracco PA, Bertoni AP, Wink MR.

Biomed Res Int. 2014;2014:123010. doi: 10.1155/2014/123010. Epub 2014 Jun 23. Review.

22.

Mesenchymal stem cells from different murine tissues have differential capacity to metabolize extracellular nucleotides.

Iser IC, Bracco PA, Gonçalves CE, Zanin RF, Nardi NB, Lenz G, Battastini AM, Wink MR.

J Cell Biochem. 2014 Oct;115(10):1673-82. doi: 10.1002/jcb.24830.

PMID:
24802095
23.

New therapy of skin repair combining adipose-derived mesenchymal stem cells with sodium carboxymethylcellulose scaffold in a pre-clinical rat model.

Rodrigues C, de Assis AM, Moura DJ, Halmenschlager G, Saffi J, Xavier LL, Fernandes Mda C, Wink MR.

PLoS One. 2014 May 2;9(5):e96241. doi: 10.1371/journal.pone.0096241. eCollection 2014.

24.

Ectonucleotidase expression profile and activity in human cervical cancer cell lines.

Beckenkamp A, Santana DB, Bruno AN, Calil LN, Casali EA, Paccez JD, Zerbini LF, Lenz G, Wink MR, Buffon A.

Biochem Cell Biol. 2014 Apr;92(2):95-104. doi: 10.1139/bcb-2013-0051. Epub 2014 Jan 8.

PMID:
24697693
25.

Purinergic signaling in glioma progression.

Braganhol E, Wink MR, Lenz G, Battastini AM.

Adv Exp Med Biol. 2013;986:81-102. doi: 10.1007/978-94-007-4719-7_5. Review.

PMID:
22879065
26.

Physical training normalizes nucleotide hydrolysis and biochemical parameters in blood serum from streptozotocin-diabetic rats.

Moritz CE, Abreu-Vieira G, Piroli C, De Senna PN, Cardoso VV, Wink MR, Harthmann Âd, Rücker B, Casali EA.

Arch Physiol Biochem. 2012 Dec;118(5):253-9. doi: 10.3109/13813455.2012.697173. Epub 2012 Jul 3.

PMID:
22758792
27.

Perspectives of purinergic signaling in stem cell differentiation and tissue regeneration.

Glaser T, Cappellari AR, Pillat MM, Iser IC, Wink MR, Battastini AM, Ulrich H.

Purinergic Signal. 2012 Sep;8(3):523-37. doi: 10.1007/s11302-011-9282-3. Epub 2011 Dec 6. Review.

28.

Overexpression of NTPDase2 in gliomas promotes systemic inflammation and pulmonary injury.

Braganhol E, Zanin RF, Bernardi A, Bergamin LS, Cappellari AR, Campesato LF, Morrone FB, Campos MM, Calixto JB, Edelweiss MI, Wink MR, Sévigny J, Robson SC, Battastini AM.

Purinergic Signal. 2012 Jun;8(2):235-43. doi: 10.1007/s11302-011-9276-1. Epub 2011 Oct 30.

29.

Ecto-5'-nucleotidase/CD73 knockdown increases cell migration and mRNA level of collagen I in a hepatic stellate cell line.

Andrade CM, Lopez PL, Noronha BT, Wink MR, Borojevic R, Margis R, Lenz G, Battastini AM, Guma FC.

Cell Tissue Res. 2011 May;344(2):279-86. doi: 10.1007/s00441-011-1140-7. Epub 2011 Mar 19.

PMID:
21424267
30.

The nucleotide hydrolysis is altered in blood serum of streptozotocin-induced diabetic rats.

Rücker B, Abreu-Vieira G, Bischoff LB, Harthmann AD, Sarkis JJ, Wink MR, Casali EA.

Arch Physiol Biochem. 2010 May;116(2):79-87. doi: 10.3109/13813451003777067.

PMID:
20420481
31.

Differential expression of nucleotide pyrophosphatase/phosphodiesterases by Walker 256 mammary cancer cells in solid tumors and malignant ascites.

Buffon A, Casali EA, Cardoso VV, Zerbini LF, Robson SC, Sarkis JJ, Wink MR.

Life Sci. 2010 Mar 13;86(11-12):435-40. doi: 10.1016/j.lfs.2010.01.015. Epub 2010 Feb 1.

PMID:
20117116
32.

Characterization of ATP-induced cell death in the GL261 mouse glioma.

Tamajusuku AS, Villodre ES, Paulus R, Coutinho-Silva R, Battasstini AM, Wink MR, Lenz G.

J Cell Biochem. 2010 Apr 1;109(5):983-91. doi: 10.1002/jcb.22478.

PMID:
20069573
33.

Changes in E-NTPDase 3 expression and extracellular nucleotide hydrolysis during the myofibroblast/lipocyte differentiation.

Andrade CM, Wink MR, Margis R, Borojevic R, Battastini AM, Guma FC.

Mol Cell Biochem. 2010 Jun;339(1-2):79-87. doi: 10.1007/s11010-009-0371-3. Epub 2010 Jan 8.

PMID:
20058055
34.

Selective NTPDase2 expression modulates in vivo rat glioma growth.

Braganhol E, Morrone FB, Bernardi A, Huppes D, Meurer L, Edelweiss MI, Lenz G, Wink MR, Robson SC, Battastini AM.

Cancer Sci. 2009 Aug;100(8):1434-42. doi: 10.1111/j.1349-7006.2009.01219.x. Epub 2009 May 18.

35.

Differential ectonucleotidase expression in human bladder cancer cell lines.

Stella J, Bavaresco L, Braganhol E, Rockenbach L, Farias PF, Wink MR, Azambuja AA, Barrios CH, Morrone FB, Oliveira Battastini AM.

Urol Oncol. 2010 May-Jun;28(3):260-7. doi: 10.1016/j.urolonc.2009.01.035. Epub 2009 Apr 16.

PMID:
19372055
36.

Activity and expression of ecto-nucleotide pyrophosphate/phosphodiesterases in a hepatic stellate cell line.

Andrade CM, Wink MR, Margis R, Borojevic R, Battastini AM, Guma FC.

Mol Cell Biochem. 2009 May;325(1-2):179-85. doi: 10.1007/s11010-009-0032-6. Epub 2009 Feb 5.

PMID:
19194664
37.

A comparative study of ectonucleotidase and P2 receptor mRNA profiles in C6 cell line cultures and C6 ex vivo glioma model.

Braganhol E, Huppes D, Bernardi A, Wink MR, Lenz G, Battastini AM.

Cell Tissue Res. 2009 Feb;335(2):331-40. doi: 10.1007/s00441-008-0723-4. Epub 2008 Nov 21.

PMID:
19023597
38.

The role of ecto-5'-nucleotidase/CD73 in glioma cell line proliferation.

Bavaresco L, Bernardi A, Braganhol E, Cappellari AR, Rockenbach L, Farias PF, Wink MR, Delgado-Cañedo A, Battastini AM.

Mol Cell Biochem. 2008 Dec;319(1-2):61-8. doi: 10.1007/s11010-008-9877-3. Epub 2008 Jul 18.

PMID:
18636315
39.

E-NTPDases and ecto-5'-nucleotidase expression profile in rat heart left ventricle and the extracellular nucleotide hydrolysis by their nerve terminal endings.

Rücker B, Almeida ME, Libermann TA, Zerbini LF, Wink MR, Sarkis JJ.

Life Sci. 2008 Feb 27;82(9-10):477-86. doi: 10.1016/j.lfs.2007.12.003. Epub 2008 Jan 16.

PMID:
18201730
40.

Activity and expression of ecto-5'-nucleotidase/CD73 are increased during phenotype conversion of a hepatic stellate cell line.

Andrade CM, Roesch GC, Wink MR, Guimarães EL, Souza LF, Jardim FR, Guaragna RM, Bernard EA, Margis R, Borojevic R, Battastini AM, Guma FC.

Life Sci. 2008 Jan 2;82(1-2):21-9. Epub 2007 Oct 23.

PMID:
18037449
41.

Biochemical characterization of ecto-nucleotide pyrophosphatase/phosphodiesterase (E-NPP, E.C. 3.1.4.1) from rat heart left ventricle.

Rücker B, Almeida ME, Libermann TA, Zerbini LF, Wink MR, Sarkis JJ.

Mol Cell Biochem. 2007 Dec;306(1-2):247-54. Epub 2007 Sep 5.

PMID:
17786543
42.

Ecto-5'-nucleotidase/CD73 inhibition by quercetin in the human U138MG glioma cell line.

Braganhol E, Tamajusuku AS, Bernardi A, Wink MR, Battastini AM.

Biochim Biophys Acta. 2007 Sep;1770(9):1352-9. Epub 2007 Jun 16.

PMID:
17643826
43.

NTPDase and 5' ecto-nucleotidase expression profiles and the pattern of extracellular ATP metabolism in the Walker 256 tumor.

Buffon A, Wink MR, Ribeiro BV, Casali EA, Libermann TA, Zerbini LF, Robson SC, Sarkis JJ.

Biochim Biophys Acta. 2007 Aug;1770(8):1259-65. Epub 2007 May 21.

PMID:
17574764
44.

Indomethacin stimulates activity and expression of ecto-5'-nucleotidase/CD73 in glioma cell lines.

Bernardi A, Bavaresco L, Wink MR, Jacques-Silva MC, Delgado-Cañedo A, Lenz G, Battastini AM.

Eur J Pharmacol. 2007 Aug 13;569(1-2):8-15. Epub 2007 May 22.

PMID:
17568578
45.

Dexamethasone inhibits proliferation and stimulates ecto-5'-nucleotidase/CD73 activity in C6 rat glioma cell line.

Bavaresco L, Bernardi A, Braganhol E, Wink MR, Battastini AM.

J Neurooncol. 2007 Aug;84(1):1-8. Epub 2007 Apr 24.

PMID:
17453149
46.

Nucleotide metabolizing ecto-enzymes in Walker 256 tumor cells: molecular identification, kinetic characterization and biochemical properties.

Buffon A, Ribeiro VB, Wink MR, Casali EA, Sarkis JJ.

Life Sci. 2007 Feb 13;80(10):950-8. Epub 2006 Nov 22.

PMID:
17169379
47.

In vivo glioblastoma growth is reduced by apyrase activity in a rat glioma model.

Morrone FB, Oliveira DL, Gamermann P, Stella J, Wofchuk S, Wink MR, Meurer L, Edelweiss MI, Lenz G, Battastini AM.

BMC Cancer. 2006 Sep 23;6:226.

48.

Antiproliferative effect of quercetin in the human U138MG glioma cell line.

Braganhol E, Zamin LL, Canedo AD, Horn F, Tamajusuku AS, Wink MR, Salbego C, Battastini AM.

Anticancer Drugs. 2006 Jul;17(6):663-71.

PMID:
16917212
49.

Activity and expression of ecto-5'-nucleotidase/CD73 are increased by thyroid hormones in vascular smooth muscle cells.

Tamajusuku AS, Carrillo-Sepúlveda MA, Braganhol E, Wink MR, Sarkis JJ, Barreto-Chaves ML, Battastini AM.

Mol Cell Biochem. 2006 Sep;289(1-2):65-72. Epub 2006 May 23.

PMID:
16718378
50.

Nucleoside triphosphate diphosphohydrolase-2 (NTPDase2/CD39L1) is the dominant ectonucleotidase expressed by rat astrocytes.

Wink MR, Braganhol E, Tamajusuku AS, Lenz G, Zerbini LF, Libermann TA, Sévigny J, Battastini AM, Robson SC.

Neuroscience. 2006;138(2):421-32. Epub 2006 Jan 18.

PMID:
16414200

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