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Items: 44

1.

Detection of Microsatellite Instability Biomarkers via Next-Generation Sequencing.

Bonneville R, Krook MA, Chen HZ, Smith A, Samorodnitsky E, Wing MR, Reeser JW, Roychowdhury S.

Methods Mol Biol. 2020;2055:119-132. doi: 10.1007/978-1-4939-9773-2_5.

PMID:
31502149
2.

Tumor heterogeneity and acquired drug resistance in FGFR2-fusion-positive cholangiocarcinoma through rapid research autopsy.

Krook MA, Bonneville R, Chen HZ, Reeser JW, Wing MR, Martin DM, Smith AM, Dao T, Samorodnitsky E, Paruchuri A, Miya J, Baker KR, Yu L, Timmers C, Dittmar K, Freud AG, Allenby P, Roychowdhury S.

Cold Spring Harb Mol Case Stud. 2019 Aug 1;5(4). pii: a004002. doi: 10.1101/mcs.a004002. Print 2019 Aug.

3.

Characterization of a KLK2-FGFR2 fusion gene in two cases of metastatic prostate cancer.

Krook MA, Barker H, Chen HZ, Reeser JW, Wing MR, Martin D, Smith AM, Dao T, Bonneville R, Samorodnitsky E, Miya J, Freud AG, Monk JP, Clinton SK, Roychowdhury S.

Prostate Cancer Prostatic Dis. 2019 Dec;22(4):624-632. doi: 10.1038/s41391-019-0145-2. Epub 2019 May 1.

4.

Genomic characterization of metastatic ultra-hypermutated interdigitating dendritic cell sarcoma through rapid research autopsy.

Chen HZ, Bonneville R, Yu L, Wing MR, Reeser JW, Krook MA, Miya J, Samorodnitsky E, Smith A, Martin D, Dao T, Guo Q, Liebner D, Freud AG, Allenby P, Roychowdhury S.

Oncotarget. 2019 Jan 8;10(3):277-288. doi: 10.18632/oncotarget.26352. eCollection 2019 Jan 8.

5.

Analytic validation and real-time clinical application of an amplicon-based targeted gene panel for advanced cancer.

Wing MR, Reeser JW, Smith AM, Reeder M, Martin D, Jewell BM, Datta J, Miya J, Monk JP, Mortazavi A, Otterson GA, Goldberg RM, VanDeusen JB, Cole S, Dittmar K, Jaiswal S, Kinzie M, Waikhom S, Freud AG, Zhou XP, Chen W, Bhatt D, Roychowdhury S.

Oncotarget. 2017 Sep 1;8(44):75822-75833. doi: 10.18632/oncotarget.20616. eCollection 2017 Sep 29.

6.

Validation of a Targeted RNA Sequencing Assay for Kinase Fusion Detection in Solid Tumors.

Reeser JW, Martin D, Miya J, Kautto EA, Lyon E, Zhu E, Wing MR, Smith A, Reeder M, Samorodnitsky E, Parks H, Naik KR, Gozgit J, Nowacki N, Davies KD, Varella-Garcia M, Yu L, Freud AG, Coleman J, Aisner DL, Roychowdhury S.

J Mol Diagn. 2017 Sep;19(5):682-696. doi: 10.1016/j.jmoldx.2017.05.006. Epub 2017 Aug 9.

7.

Inflammation and Arterial Stiffness in Chronic Kidney Disease: Findings From the CRIC Study.

Peyster E, Chen J, Feldman HI, Go AS, Gupta J, Mitra N, Pan Q, Porter A, Rahman M, Raj D, Reilly M, Wing MR, Yang W, Townsend RR; CRIC Study Investigators.

Am J Hypertens. 2017 Apr 1;30(4):400-408. doi: 10.1093/ajh/hpw164.

8.

Akt Activation Mediates Acquired Resistance to Fibroblast Growth Factor Receptor Inhibitor BGJ398.

Datta J, Damodaran S, Parks H, Ocrainiciuc C, Miya J, Yu L, Gardner EP, Samorodnitsky E, Wing MR, Bhatt D, Hays J, Reeser JW, Roychowdhury S.

Mol Cancer Ther. 2017 Apr;16(4):614-624. doi: 10.1158/1535-7163.MCT-15-1010. Epub 2017 Mar 2.

9.

Landscape of Microsatellite Instability Across 39 Cancer Types.

Bonneville R, Krook MA, Kautto EA, Miya J, Wing MR, Chen HZ, Reeser JW, Yu L, Roychowdhury S.

JCO Precis Oncol. 2017;2017. doi: 10.1200/PO.17.00073. Epub 2017 Oct 3.

10.

Gut microbiome in chronic kidney disease.

Wing MR, Patel SS, Ramezani A, Raj DS.

Exp Physiol. 2016 Apr;101(4):471-7. doi: 10.1113/EP085283. Epub 2015 Oct 2. Review.

11.

Evaluation of Hybridization Capture Versus Amplicon-Based Methods for Whole-Exome Sequencing.

Samorodnitsky E, Jewell BM, Hagopian R, Miya J, Wing MR, Lyon E, Damodaran S, Bhatt D, Reeser JW, Datta J, Roychowdhury S.

Hum Mutat. 2015 Sep;36(9):903-14. doi: 10.1002/humu.22825. Epub 2015 Jul 15.

12.

Circulating and urinary microRNA profile in focal segmental glomerulosclerosis: a pilot study.

Ramezani A, Devaney JM, Cohen S, Wing MR, Scott R, Knoblach S, Singhal R, Howard L, Kopp JB, Raj DS.

Eur J Clin Invest. 2015 Apr;45(4):394-404. doi: 10.1111/eci.12420.

13.

Comparison of custom capture for targeted next-generation DNA sequencing.

Samorodnitsky E, Datta J, Jewell BM, Hagopian R, Miya J, Wing MR, Damodaran S, Lippus JM, Reeser JW, Bhatt D, Timmers CD, Roychowdhury S.

J Mol Diagn. 2015 Jan;17(1):64-75. doi: 10.1016/j.jmoldx.2014.09.009.

14.

Association of vascular endothelial factors with cardiovascular outcome and mortality in chronic kidney disease patients: a 4-year cohort study.

Rambod M, Heine GH, Seiler S, Dominic EA, Rogacev KS, Dwivedi R, Ramezani A, Wing MR, Amdur RL, Fliser D, Raj DS.

Atherosclerosis. 2014 Oct;236(2):360-5. doi: 10.1016/j.atherosclerosis.2014.07.026. Epub 2014 Aug 12.

15.

DNA methylation profile associated with rapid decline in kidney function: findings from the CRIC study.

Wing MR, Devaney JM, Joffe MM, Xie D, Feldman HI, Dominic EA, Guzman NJ, Ramezani A, Susztak K, Herman JG, Cope L, Harmon B, Kwabi-Addo B, Gordish-Dressman H, Go AS, He J, Lash JP, Kusek JW, Raj DS; Chronic Renal Insufficiency Cohort (CRIC) Study.

Nephrol Dial Transplant. 2014 Apr;29(4):864-72. doi: 10.1093/ndt/gft537. Epub 2014 Feb 9.

16.

Race modifies the association between adiposity and inflammation in patients with chronic kidney disease: findings from the chronic renal insufficiency cohort study.

Wing MR, Yang W, Teal V, Navaneethan S, Tao K, Ojo A, Guzman NN, Reilly M, Wolman M, Rosas SE, Cuevas M, Fischer M, Lustigova E, Master SR, Xie D, Appleby D, Joffe M, Kusek J, Feldman HI, Raj DS; Chronic Renal Insufficiency Cohort (CRIC) Study.

Obesity (Silver Spring). 2014 May;22(5):1359-66. doi: 10.1002/oby.20692. Epub 2014 Feb 11.

17.

Epigenetics of progression of chronic kidney disease: fact or fantasy?

Wing MR, Ramezani A, Gill HS, Devaney JM, Raj DS.

Semin Nephrol. 2013 Jul;33(4):363-74. doi: 10.1016/j.semnephrol.2013.05.008. Review.

18.

A novel algorithm for simplification of complex gene classifiers in cancer.

Wilson RA, Teng L, Bachmeyer KM, Bissonnette ML, Husain AN, Parham DM, Triche TJ, Wing MR, Gastier-Foster JM, Barr FG, Hawkins DS, Anderson JR, Skapek SX, Volchenboum SL.

Cancer Res. 2013 Sep 15;73(18):5625-32. doi: 10.1158/0008-5472.CAN-13-0324. Epub 2013 Aug 2.

19.

Association between albuminuria, kidney function, and inflammatory biomarker profile in CKD in CRIC.

Gupta J, Mitra N, Kanetsky PA, Devaney J, Wing MR, Reilly M, Shah VO, Balakrishnan VS, Guzman NJ, Girndt M, Periera BG, Feldman HI, Kusek JW, Joffe MM, Raj DS; CRIC Study Investigators.

Clin J Am Soc Nephrol. 2012 Dec;7(12):1938-46. doi: 10.2215/CJN.03500412. Epub 2012 Sep 27.

20.

A balancing act: protein-energy wasting in chronic kidney disease.

Wing MR, Raj DS.

Am J Physiol Renal Physiol. 2012 Dec 15;303(12):F1608-9. doi: 10.1152/ajprenal.00505.2012. Epub 2012 Sep 26. No abstract available.

21.

A genome-wide association search for type 2 diabetes genes in African Americans.

Palmer ND, McDonough CW, Hicks PJ, Roh BH, Wing MR, An SS, Hester JM, Cooke JN, Bostrom MA, Rudock ME, Talbert ME, Lewis JP; DIAGRAM Consortium; MAGIC Investigators, Ferrara A, Lu L, Ziegler JT, Sale MM, Divers J, Shriner D, Adeyemo A, Rotimi CN, Ng MC, Langefeld CD, Freedman BI, Bowden DW, Voight BF, Scott LJ, Steinthorsdottir V, Morris AP, Dina C, Welch RP, Zeggini E, Huth C, Aulchenko YS, Thorleifsson G, McCulloch LJ, Ferreira T, Grallert H, Amin N, Wu G, Willer CJ, Raychaudhuri S, McCarroll SA, Langenberg C, Hofmann OM, Dupuis J, Qi L, Segrè AV, van Hoek M, Navarro P, Ardlie K, Balkau B, Benediktsson R, Bennett AJ, Blagieva R, Boerwinkle E, Bonnycastle LL, Boström KB, Bravenboer B, Bumpstead S, Burtt NP, Charpentier G, Chines PS, Cornelis M, Couper DJ, Crawford G, Doney AS, Elliott KS, Elliott AL, Erdos MR, Fox CS, Franklin CS, Ganser M, Gieger C, Grarup N, Green T, Griffin S, Groves CJ, Guiducci C, Hadjadj S, Hassanali N, Herder C, Isomaa B, Jackson AU, Johnson PR, Jørgensen T, Kao WH, Klopp N, Kong A, Kraft P, Kuusisto J, Lauritzen T, Li M, Lieverse A, Lindgren CM, Lyssenko V, Marre M, Meitinger T, Midthjell K, Morken MA, Narisu N, Nilsson P, Owen KR, Payne F, Perry JR, Petersen AK, Platou C, Proença C, Prokopenko I, Rathmann W, Rayner NW, Robertson NR, Rocheleau G, Roden M, Sampson MJ, Saxena R, Shields BM, Shrader P, Sigurdsson G, Sparsø T, Strassburger K, Stringham HM, Sun Q, Swift AJ, Thorand B, Tichet J, Tuomi T, van Dam RM, van Haeften TW, van Herpt T, van Vliet-Ostaptchouk JV, Walters GB, Weedon MN, Wijmenga C, Witteman J, Bergman RN, Cauchi S, Collins FS, Gloyn AL, Gyllensten U, Hansen T, Hide WA, Hitman GA, Hofman A, Hunter DJ, Hveem K, Laakso M, Mohlke KL, Morris AD, Palmer CN, Pramstaller PP, Rudan I, Sijbrands E, Stein LD, Tuomilehto J, Uitterlinden A, Walker M, Wareham NJ, Watanabe RM, Abecasis GR, Boehm BO, Campbell H, Daly MJ, Hattersley AT, Hu FB, Meigs JB, Pankow JS, Pedersen O, Wichmann HE, Barroso I, Florez JC, Frayling TM, Groop L, Sladek R, Thorsteinsdottir U, Wilson JF, Illig T, Froguel P, van Duijn CM, Stefansson K, Altshuler D, Boehnke M, McCarthy MI, Soranzo N, Wheeler E, Glazer NL, Bouatia-Naji N, Mägi R, Randall J, Johnson T, Elliott P, Rybin D, Henneman P, Dehghan A, Hottenga JJ, Song K, Goel A, Egan JM, Lajunen T, Doney A, Kanoni S, Cavalcanti-Proença C, Kumari M, Timpson NJ, Zabena C, Ingelsson E, An P, O'Connell J, Luan J, Elliott A, McCarroll SA, Roccasecca RM, Pattou F, Sethupathy P, Ariyurek Y, Barter P, Beilby JP, Ben-Shlomo Y, Bergmann S, Bochud M, Bonnefond A, Borch-Johnsen K, Böttcher Y, Brunner E, Bumpstead SJ, Chen YD, Chines P, Clarke R, Coin LJ, Cooper MN, Crisponi L, Day IN, de Geus EJ, Delplanque J, Fedson AC, Fischer-Rosinsky A, Forouhi NG, Frants R, Franzosi MG, Galan P, Goodarzi MO, Graessler J, Grundy S, Gwilliam R, Hallmans G, Hammond N, Han X, Hartikainen AL, Hayward C, Heath SC, Hercberg S, Hicks AA, Hillman DR, Hingorani AD, Hui J, Hung J, Jula A, Kaakinen M, Kaprio J, Kesaniemi YA, Kivimaki M, Knight B, Koskinen S, Kovacs P, Kyvik KO, Lathrop GM, Lawlor DA, Le Bacquer O, Lecoeur C, Li Y, Mahley R, Mangino M, Manning AK, Martínez-Larrad MT, McAteer JB, McPherson R, Meisinger C, Melzer D, Meyre D, Mitchell BD, Mukherjee S, Naitza S, Neville MJ, Oostra BA, Orrù M, Pakyz R, Paolisso G, Pattaro C, Pearson D, Peden JF, Pedersen NL, Perola M, Pfeiffer AF, Pichler I, Polasek O, Posthuma D, Potter SC, Pouta A, Province MA, Psaty BM, Rayner NW, Rice K, Ripatti S, Rivadeneira F, Rolandsson O, Sandbaek A, Sandhu M, Sanna S, Sayer AA, Scheet P, Seedorf U, Sharp SJ, Shields B, Sijbrands EJ, Silveira A, Simpson L, Singleton A, Smith NL, Sovio U, Swift A, Syddall H, Syvänen AC, Tanaka T, Tönjes A, Uitterlinden AG, van Dijk KW, Varma D, Visvikis-Siest S, Vitart V, Vogelzangs N, Waeber G, Wagner PJ, Walley A, Ward KL, Watkins H, Wild SH, Willemsen G, Witteman JC, Yarnell JW, Zelenika D, Zethelius B, Zhai G, Zhao JH, Zillikens MC, Borecki IB, Loos RJ, Meneton P, Magnusson PK, Nathan DM, Williams GH, Silander K, Salomaa V, Smith GD, Bornstein SR, Schwarz P, Spranger J, Karpe F, Shuldiner AR, Cooper C, Dedoussis GV, Serrano-Ríos M, Lind L, Palmer LJ, Franks PW, Ebrahim S, Marmot M, Kao WH, Pramstaller PP, Wright AF, Stumvoll M, Hamsten A, Buchanan TA, Valle TT, Rotter JI, Siscovick DS, Penninx BW, Boomsma DI, Deloukas P, Spector TD, Ferrucci L, Cao A, Scuteri A, Schlessinger D, Uda M, Ruokonen A, Jarvelin MR, Waterworth DM, Vollenweider P, Peltonen L, Mooser V, Sladek R.

PLoS One. 2012;7(1):e29202. doi: 10.1371/journal.pone.0029202. Epub 2012 Jan 4.

22.

Implication of European-derived adiposity loci in African Americans.

Hester JM, Wing MR, Li J, Palmer ND, Xu J, Hicks PJ, Roh BH, Norris JM, Wagenknecht LE, Langefeld CD, Freedman BI, Bowden DW, Ng MC.

Int J Obes (Lond). 2012 Mar;36(3):465-73. doi: 10.1038/ijo.2011.131. Epub 2011 Jul 12.

23.

Genome-wide association of BMI in African Americans.

Ng MC, Hester JM, Wing MR, Li J, Xu J, Hicks PJ, Roh BH, Lu L, Divers J, Langefeld CD, Freedman BI, Palmer ND, Bowden DW.

Obesity (Silver Spring). 2012 Mar;20(3):622-7. doi: 10.1038/oby.2011.154. Epub 2011 Jun 23.

24.

Association of PNPLA3 SNP rs738409 with liver density in African Americans with type 2 diabetes mellitus.

Cox AJ, Wing MR, Carr JJ, Hightower RC, Smith SC, Xu J, Wagenknecht LE, Bowden DW, Freedman BI.

Diabetes Metab. 2011 Nov;37(5):452-5. doi: 10.1016/j.diabet.2011.05.001. Epub 2011 Jun 14.

25.

A genome-wide association study for diabetic nephropathy genes in African Americans.

McDonough CW, Palmer ND, Hicks PJ, Roh BH, An SS, Cooke JN, Hester JM, Wing MR, Bostrom MA, Rudock ME, Lewis JP, Talbert ME, Blevins RA, Lu L, Ng MC, Sale MM, Divers J, Langefeld CD, Freedman BI, Bowden DW.

Kidney Int. 2011 Mar;79(5):563-72. doi: 10.1038/ki.2010.467. Epub 2010 Dec 8.

26.

Analysis of FTO gene variants with obesity and glucose homeostasis measures in the multiethnic Insulin Resistance Atherosclerosis Study cohort.

Wing MR, Ziegler JM, Langefeld CD, Roh BH, Palmer ND, Mayer-Davis EJ, Rewers MJ, Haffner SM, Wagenknecht LE, Bowden DW.

Int J Obes (Lond). 2011 Sep;35(9):1173-82. doi: 10.1038/ijo.2010.244. Epub 2010 Nov 23.

27.

Current treatment protocols have eliminated the prognostic advantage of type 1 fusions in Ewing sarcoma: a report from the Children's Oncology Group.

van Doorninck JA, Ji L, Schaub B, Shimada H, Wing MR, Krailo MD, Lessnick SL, Marina N, Triche TJ, Sposto R, Womer RB, Lawlor ER.

J Clin Oncol. 2010 Apr 20;28(12):1989-94. doi: 10.1200/JCO.2009.24.5845. Epub 2010 Mar 22.

28.

Genome-wide association study and follow-up analysis of adiposity traits in Hispanic Americans: the IRAS Family Study.

Norris JM, Langefeld CD, Talbert ME, Wing MR, Haritunians T, Fingerlin TE, Hanley AJ, Ziegler JT, Taylor KD, Haffner SM, Chen YD, Bowden DW, Wagenknecht LE.

Obesity (Silver Spring). 2009 Oct;17(10):1932-41. doi: 10.1038/oby.2009.143. Epub 2009 May 21.

29.

Analysis of FTO gene variants with measures of obesity and glucose homeostasis in the IRAS Family Study.

Wing MR, Ziegler J, Langefeld CD, Ng MC, Haffner SM, Norris JM, Goodarzi MO, Bowden DW.

Hum Genet. 2009 Jun;125(5-6):615-26. doi: 10.1007/s00439-009-0656-3. Epub 2009 Mar 26.

30.

Heterogeneity in gene loci associated with type 2 diabetes on human chromosome 20q13.1.

Bento JL, Palmer ND, Zhong M, Roh B, Lewis JP, Wing MR, Pandya H, Freedman BI, Langefeld CD, Rich SS, Bowden DW, Mychaleckyj JC.

Genomics. 2008 Oct;92(4):226-34. doi: 10.1016/j.ygeno.2008.06.004. Epub 2008 Aug 9.

31.

Experimental comparison and evaluation of the Affymetrix exon and U133Plus2 GeneChip arrays.

Abdueva D, Wing MR, Schaub B, Triche TJ.

PLoS One. 2007 Sep 19;2(9):e913.

32.

Galpha12/13- and rho-dependent activation of phospholipase C-epsilon by lysophosphatidic acid and thrombin receptors.

Hains MD, Wing MR, Maddileti S, Siderovski DP, Harden TK.

Mol Pharmacol. 2006 Jun;69(6):2068-75. Epub 2006 Mar 22.

PMID:
16554409
33.
34.

Rac3-mediated transformation requires multiple effector pathways.

Keller PJ, Gable CM, Wing MR, Cox AD.

Cancer Res. 2005 Nov 1;65(21):9883-90.

35.

Molecular cloning and characterization of PLC-eta2.

Zhou Y, Wing MR, Sondek J, Harden TK.

Biochem J. 2005 Nov 1;391(Pt 3):667-76.

36.

RhoA activates purified phospholipase C-epsilon by a guanine nucleotide-dependent mechanism.

Seifert JP, Wing MR, Snyder JT, Gershburg S, Sondek J, Harden TK.

J Biol Chem. 2004 Nov 12;279(46):47992-7. Epub 2004 Aug 18.

37.

PLC-epsilon: a shared effector protein in Ras-, Rho-, and G alpha beta gamma-mediated signaling.

Wing MR, Bourdon DM, Harden TK.

Mol Interv. 2003 Aug;3(5):273-80. Review.

PMID:
14993441
38.

Direct activation of phospholipase C-epsilon by Rho.

Wing MR, Snyder JT, Sondek J, Harden TK.

J Biol Chem. 2003 Oct 17;278(42):41253-8. Epub 2003 Aug 4.

39.

The pleckstrin homology domain of phospholipase C-beta2 as an effector site for Rac.

Snyder JT, Singer AU, Wing MR, Harden TK, Sondek J.

J Biol Chem. 2003 Jun 6;278(23):21099-104. Epub 2003 Mar 25.

40.

G beta association and effector interaction selectivities of the divergent G gamma subunit G gamma(13).

Blake BL, Wing MR, Zhou JY, Lei Q, Hillmann JR, Behe CI, Morris RA, Harden TK, Bayliss DA, Miller RJ, Siderovski DP.

J Biol Chem. 2001 Dec 28;276(52):49267-74. Epub 2001 Oct 23.

41.

Activation of phospholipase C-epsilon by heterotrimeric G protein betagamma-subunits.

Wing MR, Houston D, Kelley GG, Der CJ, Siderovski DP, Harden TK.

J Biol Chem. 2001 Dec 21;276(51):48257-61. Epub 2001 Oct 18.

43.

Polycyclic aromatic hydrocarbons in the atmospheres of Titan and Jupiter.

Sagan C, Khare BN, Thompson WR, McDonald GD, Wing MR, Bada JL, Vo-Dinh T, Arakawa ET.

Astrophys J. 1993 Sep 1;414(1):399-405.

PMID:
11539501
44.

Organic compounds in the Forest Vale, H4 ordinary chondrite.

Zenobi R, Philippoz JM, Zare RN, Wing MR, Bada JL, Marti K.

Geochim Cosmochim Acta. 1992 Jul;56(7):2899-905.

PMID:
11537804

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