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Inter-Individual Variation in CYP3A Activity Influences Lapatinib Bioactivation.

Bissada JE, Truong V, Abouda AA, Wines KJ, Crouch RD, Jackson KD.

Drug Metab Dispos. 2019 Sep 6. pii: dmd.119.088823. doi: 10.1124/dmd.119.088823. [Epub ahead of print]


Cytochromes P450 1A2 and 3A4 Catalyze the Metabolic Activation of Sunitinib.

Amaya GM, Durandis R, Bourgeois DS, Perkins JA, Abouda AA, Wines KJ, Mohamud M, Starks SA, Daniels RN, Jackson KD.

Chem Res Toxicol. 2018 Jul 16;31(7):570-584. doi: 10.1021/acs.chemrestox.8b00005. Epub 2018 Jun 18.

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