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Items: 1 to 50 of 187

1.

A new perspective for advanced positron emission tomography-based molecular imaging in neurodegenerative proteinopathies.

Perani D, Iaccarino L, Lammertsma AA, Windhorst AD, Edison P, Boellaard R, Hansson O, Nordberg A, Jacobs AH; IMBI Project.

Alzheimers Dement. 2019 Jun 20. pii: S1552-5260(19)30073-1. doi: 10.1016/j.jalz.2019.02.004. [Epub ahead of print]

PMID:
31230910
2.

Status of the 'consensus nomenclature rules in radiopharmaceutical sciences' initiative.

Coenen HH, Gee AD, Adam M, Antoni G, Cutler CS, Fujibayashi Y, Jeong JM, Mach RH, Mindt TL, Pike VW, Windhorst AD.

Nucl Med Biol. 2019 Apr;71:19-22. doi: 10.1016/j.nucmedbio.2019.05.001. Epub 2019 May 14. No abstract available.

PMID:
31128474
3.

Amyloid PET and cognitive decline in cognitively normal individuals: the SCIENCe project.

Timmers T, Ossenkoppele R, Verfaillie SCJ, van der Weijden CWJ, Slot RER, Wesselman LMP, Windhorst AD, Wolters EE, Yaqub M, Prins ND, Lammertsma AA, Scheltens P, van der Flier WM, van Berckel BNM.

Neurobiol Aging. 2019 Jul;79:50-58. doi: 10.1016/j.neurobiolaging.2019.02.020. Epub 2019 Mar 8.

4.

Correction: Fast and reliable generation of [18F]triflyl fluoride, a gaseous [18F]fluoride source.

Pees A, Sewing C, Vosjan MJWD, Tadino V, Herscheid JDM, Windhorst AD, Vugts DJ.

Chem Commun (Camb). 2019 May 7;55(38):5523. doi: 10.1039/c9cc90179e.

PMID:
31020289
5.

Simplified Methods for Quantification of 18F-DCFPyL Uptake in Patients with Prostate Cancer.

Jansen BHE, Yaqub M, Voortman J, Cysouw MCF, Windhorst AD, Schuit RC, Kramer GM, van den Eertwegh AJM, Schwarte LA, Hendrikse HN, Vis AN, van Moorselaar RJA, Hoekstra OS, Boellaard R, Oprea-Lager DE.

J Nucl Med. 2019 Apr 18. pii: jnumed.119.227520. doi: 10.2967/jnumed.119.227520. [Epub ahead of print]

PMID:
31000583
6.

Assessment of simplified methods for quantification of 18F-FDHT uptake in patients with metastatic castration-resistant prostate cancer.

Kramer GM, Yaqub M, Vargas HA, Schuit R, Windhorst AD, van den Eertwegh A, van der Veldt A, Bergman A, Burnazi E, Lewis JS, Chua SS, Staton K, Beattie BJ, Humm JL, Davis ID, Weickhardt A, Scott A, Morris MJ, Hoekstra OS, Lammertsma AA.

J Nucl Med. 2019 Mar 8. pii: jnumed.118.220111. doi: 10.2967/jnumed.118.220111. [Epub ahead of print]

PMID:
30850488
7.

Binding characterization of N-(2-chloro-5-thiomethylphenyl)-N'-(3-[3 H]3 methoxy phenyl)-N'-methylguanidine ([3 H]GMOM), a non-competitive N-methyl-D-aspartate (NMDA) receptor antagonist.

Metaxas A, van Berckel BNM, Klein PJ, Verbeek J, Nash EC, Kooijman EJM, Renjaän VA, Golla SSV, Boellaard R, Christiaans JAM, Windhorst AD, Leysen JE.

Pharmacol Res Perspect. 2019 Feb;7(1):e00458. doi: 10.1002/prp2.458.

8.

Parametric methods for [18F]flortaucipir PET.

Golla SS, Wolters EE, Timmers T, Ossenkoppele R, van der Weijden CW, Scheltens P, Schwarte L, Mintun MA, Devous MD Sr, Schuit RC, Windhorst AD, Lammertsma AA, Yaqub M, van Berckel BN, Boellaard R.

J Cereb Blood Flow Metab. 2018 Dec 20:271678X18820765. doi: 10.1177/0271678X18820765. [Epub ahead of print]

PMID:
30569813
9.

Identification of new molecular targets for PET imaging of the microglial anti-inflammatory activation state.

Villa A, Klein B, Janssen B, Pedragosa J, Pepe G, Zinnhardt B, Vugts DJ, Gelosa P, Sironi L, Beaino W, Damont A, Dollé F, Jego B, Winkeler A, Ory D, Solin O, Vercouillie J, Funke U, Laner-Plamberger S, Blomster LV, Christophersen P, Vegeto E, Aigner L, Jacobs A, Planas AM, Maggi A, Windhorst AD.

Theranostics. 2018 Oct 27;8(19):5400-5418. doi: 10.7150/thno.25572. eCollection 2018.

10.

Fully Automated 89Zr Labeling and Purification of Antibodies.

Poot AJ, Adamzek KWA, Windhorst AD, Vosjan MJWD, Kropf S, Wester HJ, van Dongen GAMS, Vugts DJ.

J Nucl Med. 2019 May;60(5):691-695. doi: 10.2967/jnumed.118.217158. Epub 2018 Dec 7.

PMID:
30530830
11.

A dual-labeled cRGD-based PET/optical tracer for pre-operative staging and intraoperative treatment of colorectal cancer.

Sibinga Mulder BG, Handgraaf HJ, Vugts DJ, Sewing C, Windhorst AD, Stammes M, de Geus-Oei LF, Bordo MW, Mieog JSD, van de Velde CJ, Frangioni JV, Vahrmeijer AL.

Am J Nucl Med Mol Imaging. 2018 Oct 20;8(5):282-291. eCollection 2018.

12.

In vivo assessment of neuroinflammation in progressive multiple sclerosis: a proof of concept study with [18F]DPA714 PET.

Hagens MHJ, Golla SV, Wijburg MT, Yaqub M, Heijtel D, Steenwijk MD, Schober P, Brevé JJP, Schuit RC, Reekie TA, Kassiou M, van Dam AM, Windhorst AD, Killestein J, Barkhof F, van Berckel BNM, Lammertsma AA.

J Neuroinflammation. 2018 Nov 13;15(1):314. doi: 10.1186/s12974-018-1352-9.

13.

Whole body PD-1 and PD-L1 positron emission tomography in patients with non-small-cell lung cancer.

Niemeijer AN, Leung D, Huisman MC, Bahce I, Hoekstra OS, van Dongen GAMS, Boellaard R, Du S, Hayes W, Smith R, Windhorst AD, Hendrikse NH, Poot A, Vugts DJ, Thunnissen E, Morin P, Lipovsek D, Donnelly DJ, Bonacorsi SJ, Velasquez LM, de Gruijl TD, Smit EF, de Langen AJ.

Nat Commun. 2018 Nov 7;9(1):4664. doi: 10.1038/s41467-018-07131-y.

14.

Synthesis and Preclinical Evaluation of the First Carbon-11 Labeled PET Tracers Targeting Substance P1-7.

Pekošak A, Bulc JŽ, Korat Š, Schuit RC, Kooijman E, Vos R, Rongen M, Verlaan M, Takkenkamp K, Beaino W, Poot AJ, Windhorst AD.

Mol Pharm. 2018 Nov 5;15(11):4872-4883. doi: 10.1021/acs.molpharmaceut.8b00518. Epub 2018 Oct 25.

15.

Evaluation of the Novel PET Tracer [11C]HACH242 for Imaging the GluN2B NMDA Receptor in Non-Human Primates.

van der Aart J, Yaqub M, Kooijman EJM, Bakker J, Langermans JAM, Schuit RC, Hofman MBM, Christiaans JAM, Lammertsma AA, Windhorst AD, van Berckel BNM.

Mol Imaging Biol. 2019 Aug;21(4):676-685. doi: 10.1007/s11307-018-1284-x.

PMID:
30306318
16.

Synthesis and preliminary preclinical evaluation of fluorine-18 labelled isatin-4-(4-methoxyphenyl)-3-thiosemicarbazone ([18F]4FIMPTC) as a novel PET tracer of P-glycoprotein expression.

Verbeek J, Eriksson J, Syvänen S, Huisman M, Schuit RC, Molthoff CFM, Voskuyl RA, de Lange EC, Lammertsma AA, Windhorst AD.

EJNMMI Radiopharm Chem. 2018 Sep 21;3:11. doi: 10.1186/s41181-018-0046-z. eCollection 2018 Dec.

17.

Fast and reliable generation of [18F]triflyl fluoride, a gaseous [18F]fluoride source.

Pees A, Sewing C, Vosjan MJWD, Tadino V, Herscheid JDM, Windhorst AD, Vugts DJ.

Chem Commun (Camb). 2018 Sep 6;54(72):10179-10182. doi: 10.1039/c8cc03206h. Erratum in: Chem Commun (Camb). 2019 May 7;55(38):5523.

PMID:
30137103
18.

A novel partial volume correction method for accurate quantification of [18F] flortaucipir in the hippocampus.

Wolters EE, Golla SSV, Timmers T, Ossenkoppele R, van der Weijden CWJ, Scheltens P, Schwarte L, Schuit RC, Windhorst AD, Barkhof F, Yaqub M, Lammertsma AA, Boellaard R, van Berckel BNM.

EJNMMI Res. 2018 Aug 15;8(1):79. doi: 10.1186/s13550-018-0432-2.

19.

Quantification of O-(2-[18F]fluoroethyl)-L-tyrosine kinetics in glioma.

Koopman T, Verburg N, Schuit RC, Pouwels PJW, Wesseling P, Windhorst AD, Hoekstra OS, de Witt Hamer PC, Lammertsma AA, Boellaard R, Yaqub M.

EJNMMI Res. 2018 Jul 31;8(1):72. doi: 10.1186/s13550-018-0418-0.

20.

Improving metabolic stability of fluorine-18 labeled verapamil analogs.

Raaphorst RM, Luurtsema G, Schokker CJ, Attia KA, Schuit RC, Elsinga PH, Lammertsma AA, Windhorst AD.

Nucl Med Biol. 2018 Sep - Oct;64-65:47-56. doi: 10.1016/j.nucmedbio.2018.06.009. Epub 2018 Jul 5.

21.

First in human evaluation of [18F]PK-209, a PET ligand for the ion channel binding site of NMDA receptors.

van der Aart J, Golla SSV, van der Pluijm M, Schwarte LA, Schuit RC, Klein PJ, Metaxas A, Windhorst AD, Boellaard R, Lammertsma AA, van Berckel BNM.

EJNMMI Res. 2018 Jul 27;8(1):69. doi: 10.1186/s13550-018-0424-2.

22.

Quantification of [18F]florbetapir: A test-retest tracer kinetic modelling study.

Golla SS, Verfaillie SC, Boellaard R, Adriaanse SM, Zwan MD, Schuit RC, Timmers T, Groot C, Schober P, Scheltens P, van der Flier WM, Windhorst AD, van Berckel BN, Lammertsma AA.

J Cereb Blood Flow Metab. 2018 Jun 13:271678X18783628. doi: 10.1177/0271678X18783628. [Epub ahead of print]

PMID:
29897009
23.

Prophylactic and therapeutic activity of alkaline phosphatase in arthritic rats: single-agent effects of alkaline phosphatase and synergistic effects in combination with methotrexate.

Chandrupatla DMSH, Molthoff CFM, Ritsema WIGR, Vos R, Elshof E, Matsuyama T, Low PS, Musters RJP, Hammond A, Windhorst AD, Lammertsma AA, van der Laken CJ, Brands R, Jansen G.

Transl Res. 2018 Sep;199:24-38. doi: 10.1016/j.trsl.2018.04.001. Epub 2018 May 17.

24.

In vivo evaluation of two tissue transglutaminase PET tracers in an orthotopic tumour xenograft model.

van der Wildt B, Wilhelmus MMM, Beaino W, Kooijman EJM, Schuit RC, Bol JGJM, Breve JJP, Pasternack R, Lammertsma AA, Windhorst AD, Drukarch B.

EJNMMI Res. 2018 May 25;8(1):39. doi: 10.1186/s13550-018-0388-2.

25.

Identification of the allosteric P2X7 receptor antagonist [11C]SMW139 as a PET tracer of microglial activation.

Janssen B, Vugts DJ, Wilkinson SM, Ory D, Chalon S, Hoozemans JJM, Schuit RC, Beaino W, Kooijman EJM, van den Hoek J, Chishty M, Doméné A, Van der Perren A, Villa A, Maggi A, Molenaar GT, Funke U, Shevchenko RV, Baekelandt V, Bormans G, Lammertsma AA, Kassiou M, Windhorst AD.

Sci Rep. 2018 Apr 26;8(1):6580. doi: 10.1038/s41598-018-24814-0.

26.

Imaging and Methotrexate Response Monitoring of Systemic Inflammation in Arthritic Rats Employing the Macrophage PET Tracer [18F]Fluoro-PEG-Folate.

Chandrupatla DMSH, Jansen G, Mantel E, Low PS, Matsuyama T, Musters RP, Windhorst AD, Lammertsma AA, Molthoff CFM, van der Laken CJ.

Contrast Media Mol Imaging. 2018 Feb 21;2018:8092781. doi: 10.1155/2018/8092781. eCollection 2018.

27.

Reproducibility and Repeatability of Semiquantitative 18F-Fluorodihydrotestosterone Uptake Metrics in Castration-Resistant Prostate Cancer Metastases: A Prospective Multicenter Study.

Vargas HA, Kramer GM, Scott AM, Weickhardt A, Meier AA, Parada N, Beattie BJ, Humm JL, Staton KD, Zanzonico PB, Lyashchenko SK, Lewis JS, Yaqub M, Sosa RE, van den Eertwegh AJ, Davis ID, Ackermann U, Pathmaraj K, Schuit RC, Windhorst AD, Chua S, Weber WA, Larson SM, Scher HI, Lammertsma AA, Hoekstra OS, Morris MJ.

J Nucl Med. 2018 Oct;59(10):1516-1523. doi: 10.2967/jnumed.117.206490. Epub 2018 Apr 6.

28.

Letter to the Editor: International Consensus Radiochemistry Nomenclature Guidelines.

Coenen HH, Gee AD, Adam M, Antoni G, Cutler CS, Fujibayashi Y, Jeong JM, Mach RH, Mindt TL, Pike VW, Windhorst AD.

Curr Radiopharm. 2018;11(1):73-75. doi: 10.2174/187447101101180404111248. No abstract available.

PMID:
29624156
29.

International Consensus Radiochemistry Nomenclature Guidelines.

Coenen HH, Gee AD, Adam M, Antoni G, Cutler CS, Fujibayashi Y, Jeong JM, Mach RH, Mindt TL, Pike VW, Windhorst AD.

Nuklearmedizin. 2018 Feb;57(1):40-41. doi: 10.1055/s-0038-1636563. Epub 2018 Feb 21. No abstract available.

PMID:
29536500
30.

Open letter to journal editors on: international consensus radiochemistry nomenclature guidelines.

Coenen HH, Gee AD, Adam M, Antoni G, Cutler CS, Fujibayashi Y, Jeong JM, Mach RH, Mindt TL, Pike VW, Windhorst AD.

Am J Nucl Med Mol Imaging. 2018 Feb 5;8(1):70-72. eCollection 2018. No abstract available.

31.

PET Imaging of Microglial Activation-Beyond Targeting TSPO.

Janssen B, Vugts DJ, Windhorst AD, Mach RH.

Molecules. 2018 Mar 8;23(3). pii: E607. doi: 10.3390/molecules23030607. Review.

32.

Open letter to journal editors on: International Consensus Radiochemistry Nomenclature Guidelines.

Coenen HH, Gee AD, Adam M, Antoni G, Cutler CS, Fujibayashi Y, Jeong JM, Mach RH, Mindt TL, Pike VW, Windhorst AD.

Nucl Med Commun. 2018 Mar;39(3):193-195. doi: 10.1097/MNM.0000000000000799. No abstract available.

PMID:
29438216
33.

Open letter to journal editors on: International Consensus Radiochemistry Nomenclature Guidelines.

Coenen HH, Gee AD, Adam M, Antoni G, Cutler CS, Fujibayashi Y, Jeong JM, Mach RH, Mindt TL, Pike VW, Windhorst AD.

Ann Nucl Med. 2018 Apr;32(3):236-238. doi: 10.1007/s12149-018-1238-z. Epub 2018 Feb 8. No abstract available.

34.

From Carbon-11-Labeled Amino Acids to Peptides in Positron Emission Tomography: the Synthesis and Clinical Application.

Pekošak A, Filp U, Poot AJ, Windhorst AD.

Mol Imaging Biol. 2018 Aug;20(4):510-532. doi: 10.1007/s11307-018-1163-5. Review.

PMID:
29411226
35.

Open letter to journal editors on: International consensus radiochemistry nomenclature guidelines.

Coenen HH, Gee AD, Adam M, Antoni G, Cutler CS, Fujibayashi Y, Jeong JM, Mach RH, Mindt TL, Pike VW, Windhorst AD.

J Labelled Comp Radiopharm. 2018 Apr;61(4):402-404. doi: 10.1002/jlcr.3604. No abstract available.

PMID:
29331022
36.

Purinergic receptors P2Y12R and P2X7R: potential targets for PET imaging of microglia phenotypes in multiple sclerosis.

Beaino W, Janssen B, Kooij G, van der Pol SMA, van Het Hof B, van Horssen J, Windhorst AD, de Vries HE.

J Neuroinflammation. 2017 Dec 22;14(1):259. doi: 10.1186/s12974-017-1034-z.

37.

Model selection criteria for dynamic brain PET studies.

Golla SSV, Adriaanse SM, Yaqub M, Windhorst AD, Lammertsma AA, van Berckel BNM, Boellaard R.

EJNMMI Phys. 2017 Dec 6;4(1):30. doi: 10.1186/s40658-017-0197-0.

38.

Novel molecular imaging ligands targeting matrix metalloproteinases 2 and 9 for imaging of unstable atherosclerotic plaques.

Hakimzadeh N, Pinas VA, Molenaar G, de Waard V, Lutgens E, van Eck-Smit BLF, de Bruin K, Piek JJ, Eersels JLH, Booij J, Verberne HJ, Windhorst AD.

PLoS One. 2017 Nov 30;12(11):e0187767. doi: 10.1371/journal.pone.0187767. eCollection 2017.

39.

The past, present, and the promise of the future of nuclear medicine and biology.

Eckelman WC, Windhorst AD, O'Hara C.

Nucl Med Biol. 2017 Dec;55:47-48. doi: 10.1016/j.nucmedbio.2017.10.002. Epub 2017 Oct 12. No abstract available.

PMID:
29117904
40.

Consensus nomenclature rules for radiopharmaceutical chemistry - Setting the record straight.

Coenen HH, Gee AD, Adam M, Antoni G, Cutler CS, Fujibayashi Y, Jeong JM, Mach RH, Mindt TL, Pike VW, Windhorst AD.

Nucl Med Biol. 2017 Dec;55:v-xi. doi: 10.1016/j.nucmedbio.2017.09.004. Epub 2017 Oct 2. Review.

PMID:
29074076
41.

Comparison of In Vitro Assays in Selecting Radiotracers for In Vivo P-Glycoprotein PET Imaging.

Raaphorst RM, Savolainen H, Cantore M, van de Steeg E, van Waarde A, Colabufo NA, Elsinga PH, Lammertsma AA, Windhorst AD, Luurtsema G.

Pharmaceuticals (Basel). 2017 Sep 20;10(3). pii: E76. doi: 10.3390/ph10030076.

42.

Pharmacological Evaluation of Novel Bioisosteres of an Adamantanyl Benzamide P2X7 Receptor Antagonist.

Wilkinson SM, Barron ML, O'Brien-Brown J, Janssen B, Stokes L, Werry EL, Chishty M, Skarratt KK, Ong JA, Hibbs DE, Vugts DJ, Fuller S, Windhorst AD, Kassiou M.

ACS Chem Neurosci. 2017 Nov 15;8(11):2374-2380. doi: 10.1021/acschemneuro.7b00272. Epub 2017 Aug 25.

PMID:
28841278
43.

Radiosynthesis of 1-iodo-2-[11 C]methylpropane and 2-methyl-1-[11 C]propanol and its application for alkylation reactions and C-C bond formation.

Rotteveel L, Poot AJ, Funke U, Pekošak A, Filp U, Lammertsma AA, Windhorst AD.

J Labelled Comp Radiopharm. 2017 Oct;60(12):566-576. doi: 10.1002/jlcr.3536. Epub 2017 Sep 26.

PMID:
28755455
44.

Synthesis and Evaluation of New Fluorine-18 Labeled Verapamil Analogs To Investigate the Function of P-Glycoprotein in the Blood-Brain Barrier.

Raaphorst RM, Luurtsema G, Schuit RC, Kooijman EJM, Elsinga PH, Lammertsma AA, Windhorst AD.

ACS Chem Neurosci. 2017 Sep 20;8(9):1925-1936. doi: 10.1021/acschemneuro.7b00086. Epub 2017 Jul 10.

45.

Pretargeted PET Imaging of trans-Cyclooctene-Modified Porous Silicon Nanoparticles.

Keinänen O, Mäkilä EM, Lindgren R, Virtanen H, Liljenbäck H, Oikonen V, Sarparanta M, Molthoff C, Windhorst AD, Roivainen A, Salonen JJ, Airaksinen AJ.

ACS Omega. 2017 Jan 31;2(1):62-69. doi: 10.1021/acsomega.6b00269. Epub 2017 Jan 6.

46.

Fluorine-18 labelled building blocks for PET tracer synthesis.

van der Born D, Pees A, Poot AJ, Orru RVA, Windhorst AD, Vugts DJ.

Chem Soc Rev. 2017 Jul 31;46(15):4709-4773. doi: 10.1039/c6cs00492j. Review.

PMID:
28608906
47.

In-vivo monitoring of anti-folate therapy in arthritic rats using [18F]fluoro-PEG-folate and positron emission tomography.

Chandrupatla DMSH, Jansen G, Vos R, Verlaan M, Chen Q, Low PS, Windhorst AD, Lammertsma AA, van der Laken CJ, Molthoff CFM.

Arthritis Res Ther. 2017 May 31;19(1):114. doi: 10.1186/s13075-017-1325-x.

48.

Synthesis, radiolabeling and preclinical evaluation of a [11C]GMOM derivative as PET radiotracer for the ion channel of the N-methyl-D-aspartate receptor.

Klein PJ, Schuit RC, Metaxas A, Christiaans JAM, Kooijman E, Lammertsma AA, van Berckel BNM, Windhorst AD.

Nucl Med Biol. 2017 Aug;51:25-32. doi: 10.1016/j.nucmedbio.2017.05.003. Epub 2017 May 8.

49.

Development of [11C]vemurafenib employing a carbon-11 carbonylative Stille coupling and preliminary evaluation in mice bearing melanoma tumor xenografts.

Slobbe P, Windhorst AD, Adamzek K, Bolijn M, Schuit RC, Heideman DAM, van Dongen GAMS, Poot AJ.

Oncotarget. 2017 Jun 13;8(24):38337-38350. doi: 10.18632/oncotarget.16321.

50.

Quantification of Tau Load Using [18F]AV1451 PET.

Golla SSV, Timmers T, Ossenkoppele R, Groot C, Verfaillie S, Scheltens P, van der Flier WM, Schwarte L, Mintun MA, Devous M, Schuit RC, Windhorst AD, Lammertsma AA, Boellaard R, van Berckel BNM, Yaqub M.

Mol Imaging Biol. 2017 Dec;19(6):963-971. doi: 10.1007/s11307-017-1080-z.

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