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Items: 1 to 50 of 266

1.

Addressing Heterogeneity in Als Clinical Trials.

Goyal NA, Berry JD, Windebank A, Nathan P, Maragakis NJ, van den Berg LH, Genge A, Miller R, Baloh RH, Kern R, Gothelf Y, Lebovits C, Cudkowicz M.

Muscle Nerve. 2020 Jan 3. doi: 10.1002/mus.26801. [Epub ahead of print] Review.

PMID:
31899540
2.

CELLTOP Clinical Trial: First Report From a Phase 1 Trial of Autologous Adipose Tissue-Derived Mesenchymal Stem Cells in the Treatment of Paralysis Due to Traumatic Spinal Cord Injury.

Bydon M, Dietz AB, Goncalves S, Moinuddin FM, Alvi MA, Goyal A, Yolcu Y, Hunt CL, Garlanger KL, Del Fabro AS, Reeves RK, Terzic A, Windebank AJ, Qu W.

Mayo Clin Proc. 2019 Nov 27. pii: S0025-6196(19)30871-7. doi: 10.1016/j.mayocp.2019.10.008. [Epub ahead of print]

PMID:
31785831
3.

NurOwn, phase 2, randomized, clinical trial in patients with ALS: Safety, clinical, and biomarker results.

Berry JD, Cudkowicz ME, Windebank AJ, Staff NP, Owegi M, Nicholson K, McKenna-Yasek D, Levy YS, Abramov N, Kaspi H, Mehra M, Aricha R, Gothelf Y, Brown RH.

Neurology. 2019 Dec 10;93(24):e2294-e2305. doi: 10.1212/WNL.0000000000008620. Epub 2019 Nov 18.

PMID:
31740545
4.

Intrathecal administration of autologous mesenchymal stem cells in multiple system atrophy.

Singer W, Dietz AB, Zeller AD, Gehrking TL, Schmelzer JD, Schmeichel AM, Gehrking JA, Suarez MD, Sletten DM, Minota Pacheco KV, Coon EA, Sandroni P, Benarroch EE, Fealey RD, Matsumoto JY, Bower JH, Hassan A, McKeon A, Windebank AJ, Mandrekar JN, Low PA.

Neurology. 2019 Jul 2;93(1):e77-e87. doi: 10.1212/WNL.0000000000007720. Epub 2019 May 31.

PMID:
31152011
5.

Glucocorticoids Target Ependymal Glia and Inhibit Repair of the Injured Spinal Cord.

Nelson CM, Lennon VA, Lee H, Krug RG 2nd, Kamalova A, Madigan NN, Clark KJ, Windebank AJ, Henley JR.

Front Cell Dev Biol. 2019 Apr 24;7:56. doi: 10.3389/fcell.2019.00056. eCollection 2019.

6.

Combinatorial tissue engineering partially restores function after spinal cord injury.

Hakim JS, Rodysill BR, Chen BK, Schmeichel AM, Yaszemski MJ, Windebank AJ, Madigan NN.

J Tissue Eng Regen Med. 2019 May;13(5):857-873. doi: 10.1002/term.2840. Epub 2019 Mar 20.

PMID:
30808065
7.

Drosophila strain specific response to cisplatin neurotoxicity.

Groen CM, Podratz JL, Treb K, Windebank AJ.

Fly (Austin). 2018;12(3-4):174-182. doi: 10.1080/19336934.2019.1565257. Epub 2019 Jan 22.

PMID:
30668272
8.

Mechanisms Underlying the Regulation of HP1γ by the NGF-PKA Signaling Pathway.

Seo S, Mathison A, Grzenda A, Podratz J, Calvo E, Brimijoin S, Windebank A, Iovanna J, Lomberk G, Urrutia R.

Sci Rep. 2018 Oct 10;8(1):15077. doi: 10.1038/s41598-018-33475-y.

9.

Case-Based Learning in Translational Biomedical Research Education: Providing Realistic and Adaptive Skills for Early-Career Scientists.

Greenberg-Worisek AJ, Campbell KA, Klee EW, Staff NP, Schimmenti LA, Weavers KM, Ekker SC, Windebank AJ.

Acad Med. 2019 Feb;94(2):213-216. doi: 10.1097/ACM.0000000000002470.

PMID:
30256254
10.

Chimeric Antigen Receptor T-Cells: Successful Translation of the First Cell and Gene Therapy From Bench to Bedside.

Rodriguez-Cartagena LG, Bowles BS, Kurani SS, Windebank AJ, Kenderian SS, Greenberg-Worisek AJ.

Clin Transl Sci. 2018 Nov;11(6):537-539. doi: 10.1111/cts.12586. Epub 2018 Sep 22. No abstract available.

11.

Establishing a Current Good Manufacturing Practice Facility for Biomaterials and Biomolecules in an Academic Medical Center.

Greenberg-Worisek AJ, Runge BK, Solyntjes SA, St Helene-Kraft J, Glass SL, Waletzki BE, Herrick JL, Miller AL 2nd, Yaszemski MJ, Windebank AJ, Wang H.

Tissue Eng Part B Rev. 2018 Dec;24(6):493-498. doi: 10.1089/ten.TEB.2018.0114. Epub 2018 Sep 21. Review.

PMID:
30084747
12.

Incidence and disease burden of chemotherapy-induced peripheral neuropathy in a population-based cohort.

Shah A, Hoffman EM, Mauermann ML, Loprinzi CL, Windebank AJ, Klein CJ, Staff NP.

J Neurol Neurosurg Psychiatry. 2018 Jun;89(6):636-641. doi: 10.1136/jnnp-2017-317215. Epub 2018 Feb 8.

13.

Composite ganglioside autoantibodies and immune treatment response in MMN and MADSAM.

Martinez-Thompson JM, Snyder MR, Ettore M, McKeon A, Pittock SJ, Roforth MM, Mandrekar J, Mauermann ML, Taylor BV, Dyck PJB, Windebank AJ, Klein CJ.

Muscle Nerve. 2018 Jun;57(6):1000-1005. doi: 10.1002/mus.26051. Epub 2018 Jan 26.

PMID:
29272035
14.

Navigating the Clinical Translation of Medical Devices: The Case of Radiofrequency Ablation.

Armaiz Flores A, Oppenheimer Velez ML, Thompson SM, Windebank AJ, Greenberg-Worisek AJ.

Clin Transl Sci. 2018 Jan;11(1):8-10. doi: 10.1111/cts.12516. Epub 2017 Nov 18. No abstract available.

15.

A novel triple immunoenzyme staining enables simultaneous identification of all muscle fiber types on a single skeletal muscle cryosection from normal, denervated or reinnervated rats.

Wu P, Zhang S, Spinner RJ, Lizardi MT, Gu Y, Yu C, Yaszemski MJ, Windebank AJ, Wang H.

Neural Regen Res. 2017 Aug;12(8):1357-1364. doi: 10.4103/1673-5374.213560.

16.

Genome editing technologies and their potential to treat neurologic disease.

Madigan NN, Staff NP, Windebank AJ, Benarroch EE.

Neurology. 2017 Oct 17;89(16):1739-1748. doi: 10.1212/WNL.0000000000004558. Epub 2017 Sep 20. No abstract available.

17.

Comprehensive immune profiling reveals substantial immune system alterations in a subset of patients with amyotrophic lateral sclerosis.

Gustafson MP, Staff NP, Bornschlegl S, Butler GW, Maas ML, Kazamel M, Zubair A, Gastineau DA, Windebank AJ, Dietz AB.

PLoS One. 2017 Jul 25;12(7):e0182002. doi: 10.1371/journal.pone.0182002. eCollection 2017.

18.

Mechano growth factor, a splice variant of IGF-1, promotes neurogenesis in the aging mouse brain.

Tang JJ, Podratz JL, Lange M, Scrable HJ, Jang MH, Windebank AJ.

Mol Brain. 2017 Jul 7;10(1):23. doi: 10.1186/s13041-017-0304-0.

19.

Promoting international collaboration and creativity in doctoral students.

Groen CM, McGrath C, Campbell KA, Götherström C, Windebank AJ, Landázuri N.

Elife. 2017 Jun 22;6. pii: e26787. doi: 10.7554/eLife.26787.

20.

Chemotherapy-induced peripheral neuropathy: A current review.

Staff NP, Grisold A, Grisold W, Windebank AJ.

Ann Neurol. 2017 Jun;81(6):772-781. doi: 10.1002/ana.24951. Epub 2017 Jun 5. Review.

21.

Increased Seat Dump Angle in a Manual Wheelchair Is Associated With Changes in Thoracolumbar Lordosis and Scapular Kinematics During Propulsion.

Cloud BA, Zhao KD, Ellingson AM, Nassr A, Windebank AJ, An KN.

Arch Phys Med Rehabil. 2017 Oct;98(10):2021-2027.e2. doi: 10.1016/j.apmr.2017.02.014. Epub 2017 Mar 18.

22.

GDNF Schwann cells in hydrogel scaffolds promote regional axon regeneration, remyelination and functional improvement after spinal cord transection in rats.

Chen BK, Madigan NN, Hakim JS, Dadsetan M, McMahon SS, Yaszemski MJ, Windebank AJ.

J Tissue Eng Regen Med. 2018 Jan;12(1):e398-e407. doi: 10.1002/term.2431. Epub 2017 Jun 26.

PMID:
28296347
23.

Safety of intrathecal autologous adipose-derived mesenchymal stromal cells in patients with ALS.

Staff NP, Madigan NN, Morris J, Jentoft M, Sorenson EJ, Butler G, Gastineau D, Dietz A, Windebank AJ.

Neurology. 2016 Nov 22;87(21):2230-2234. Epub 2016 Oct 26.

24.

Cisplatin induces mitochondrial deficits in Drosophila larval segmental nerve.

Podratz JL, Lee H, Knorr P, Koehler S, Forsythe S, Lambrecht K, Arias S, Schmidt K, Steinhoff G, Yudintsev G, Yang A, Trushina E, Windebank A.

Neurobiol Dis. 2017 Jan;97(Pt A):60-69. doi: 10.1016/j.nbd.2016.10.003. Epub 2016 Oct 17.

25.

Nerve Guidance by a Decellularized Fibroblast Extracellular Matrix.

Harris GM, Madigan NN, Lancaster KZ, Enquist LW, Windebank AJ, Schwartz J, Schwarzbauer JE.

Matrix Biol. 2017 Jul;60-61:176-189. doi: 10.1016/j.matbio.2016.08.011. Epub 2016 Sep 15.

26.

The Value of Systematic Reviews in Estimating the Cost and Barriers to Translation in Tissue Engineering.

Cousin MA, Greenberg AJ, Koep TH, Angius D, Yaszemski MJ, Spinner RJ, Windebank AJ.

Tissue Eng Part B Rev. 2016 Dec;22(6):430-437. Epub 2016 Aug 22. Review.

27.

Neurotoxicity to DRG neurons varies between rodent strains treated with cisplatin and bortezomib.

Podratz JL, Kulkarni A, Pleticha J, Kanwar R, Beutler AS, Staff NP, Windebank AJ.

J Neurol Sci. 2016 Mar 15;362:131-5. doi: 10.1016/j.jns.2015.12.038. Epub 2015 Dec 28.

28.

Adult polyglucosan body disease presenting as a unilateral progressive plexopathy.

Naddaf E, Kassardjian CD, Kurt YG, Akman HO, Windebank AJ.

Muscle Nerve. 2016 Jun;53(6):976-81. doi: 10.1002/mus.25041. Epub 2016 Apr 25.

PMID:
26789422
29.

Editorial by concerned physicians: Unintended effect of the orphan drug act on the potential cost of 3,4-diaminopyridine.

Burns TM, Smith GA, Allen JA, Amato AA, Arnold WD, Barohn R, Benatar M, Bird SJ, Bromberg M, Chahin N, Ciafaloni E, Cohen JA, Corse A, Crum BA, David WS, Dimberg E, Sousa EA, Donofrio PD, Dyck PJ, Engel AG, Ensrud ER, Ferrante M, Freimer M, Gable KL, Gibson S, Gilchrist JM, Goldstein JM, Gooch CL, Goodman BP, Gorelov D, Gospe SM Jr, Goyal NA, Guidon AC, Guptill JT, Gutmann L, Gutmann L, Gwathmey K, Harati Y, Harper CM Jr, Hehir MK, Hobson-Webb LD, Howard JF Jr, Jackson CE, Johnson N, Jones SM, Juel VC, Kaminski HJ, Karam C, Kennelly KD, Khella S, Khoury J, Kincaid JC, Kissel JT, Kolb N, Lacomis D, Ladha S, Larriviere D, Lewis RA, Li Y, Litchy WJ, Logigian E, Lou JS, MacGowen DJ, Maselli R, Massey JM, Mauermann ML, Mathews KD, Meriggioli MN, Miller RG, Moon JS, Mozaffar T, Nations SP, Nowak RJ, Ostrow LW, Pascuzzi RM, Peltier A, Ruzhansky K, Richman DP, Ross MA, Rubin DI, Russell JA, Sachs GM, Salajegheh MK, Saperstein DS, Scelsa S, Selcen D, Shaibani A, Shieh PB, Silvestri NJ, Singleton JR, Smith BE, So YT, Solorzano G, Sorenson EJ, Srinivasen J, Tavee J, Tawil R, Thaisetthawatkul P, Thornton C, Trivedi J, Vernino S, Wang AK, Webb TA, Weiss MD, Windebank AJ, Wolfe GI.

Muscle Nerve. 2016 Feb;53(2):165-8. doi: 10.1002/mus.25009. Epub 2015 Dec 21. No abstract available.

PMID:
26662952
30.

Translating stem cell research to the clinic: a primer on translational considerations for your first stem cell protocol.

O'Brien T, Creane M, Windebank AJ, Terzic A, Dietz AB.

Stem Cell Res Ther. 2015 Aug 22;6:146. doi: 10.1186/s13287-015-0145-7.

31.

Positively Charged Oligo[Poly(Ethylene Glycol) Fumarate] Scaffold Implantation Results in a Permissive Lesion Environment after Spinal Cord Injury in Rat.

Hakim JS, Esmaeili Rad M, Grahn PJ, Chen BK, Knight AM, Schmeichel AM, Isaq NA, Dadsetan M, Yaszemski MJ, Windebank AJ.

Tissue Eng Part A. 2015 Jul;21(13-14):2099-114. doi: 10.1089/ten.TEA.2015.0019.

32.

Candidate pathway-based genetic association study of platinum and platinum-taxane related toxicity in a cohort of primary lung cancer patients.

Johnson C, Pankratz VS, Velazquez AI, Aakre JA, Loprinzi CL, Staff NP, Windebank AJ, Yang P.

J Neurol Sci. 2015 Feb 15;349(1-2):124-8. doi: 10.1016/j.jns.2014.12.041. Epub 2015 Jan 5.

33.

Key changes in denervated muscles and their impact on regeneration and reinnervation.

Wu P, Chawla A, Spinner RJ, Yu C, Yaszemski MJ, Windebank AJ, Wang H.

Neural Regen Res. 2014 Oct 15;9(20):1796-809. doi: 10.4103/1673-5374.143424. Review.

34.

A safety study on intrathecal delivery of autologous mesenchymal stromal cells in rabbits directly supporting Phase I human trials.

Chen BK, Staff NP, Knight AM, Nesbitt JJ, Butler GW, Padley DJ, Parisi JE, Dietz AB, Windebank AJ.

Transfusion. 2015 May;55(5):1013-20. doi: 10.1111/trf.12938. Epub 2014 Nov 21.

35.

Peripheral neuropathy due to vitamin deficiency, toxins, and medications.

Staff NP, Windebank AJ.

Continuum (Minneap Minn). 2014 Oct;20(5 Peripheral Nervous System Disorders):1293-306. doi: 10.1212/01.CON.0000455880.06675.5a. Review.

36.

Breaking down translation barriers: investigator's perspective.

Staff NP, Runge BK, Windebank AJ.

Sci Transl Med. 2014 Sep 3;6(252):252cm7. doi: 10.1126/scitranslmed.3008252. No abstract available.

PMID:
25186172
37.

Sequencing of Charcot-Marie-Tooth disease genes in a toxic polyneuropathy.

Beutler AS, Kulkarni AA, Kanwar R, Klein CJ, Therneau TM, Qin R, Banck MS, Boora GK, Ruddy KJ, Wu Y, Smalley RL, Cunningham JM, Le-Lindqwister NA, Beyerlein P, Schroth GP, Windebank AJ, Züchner S, Loprinzi CL.

Ann Neurol. 2014 Nov;76(5):727-37. doi: 10.1002/ana.24265. Epub 2014 Sep 17.

38.

Comparison of cellular architecture, axonal growth, and blood vessel formation through cell-loaded polymer scaffolds in the transected rat spinal cord.

Madigan NN, Chen BK, Knight AM, Rooney GE, Sweeney E, Kinnavane L, Yaszemski MJ, Dockery P, O'Brien T, McMahon SS, Windebank AJ.

Tissue Eng Part A. 2014 Nov;20(21-22):2985-97. doi: 10.1089/ten.TEA.2013.0551. Epub 2014 Aug 11.

39.

Non-invasive isometric force measurement of plantar flexors in rats.

Chawla A, Spinner RJ, Torres Lizardi M, Yaszemski MJ, Windebank AJ, Wang H.

Muscle Nerve. 2014 Nov;50(5):812-21. doi: 10.1002/mus.24219. Epub 2014 Sep 16.

PMID:
24639363
40.

Rituximab for non-Hodgkin's lymphoma: a story of rapid success in translation.

Harrison AM, Thalji NM, Greenberg AJ, Tapia CJ, Windebank AJ.

Clin Transl Sci. 2014 Feb;7(1):82-6. doi: 10.1111/cts.12111. Epub 2013 Oct 3.

41.

Implantation of cauda equina nerve roots through a biodegradable scaffold at the conus medullaris in rat.

Grahn PJ, Vaishya S, Knight AM, Chen BK, Schmeichel AM, Currier BL, Spinner RJ, Yaszemski MJ, Windebank AJ.

Spine J. 2014 Sep 1;14(9):2172-7. doi: 10.1016/j.spinee.2014.01.059. Epub 2014 Feb 6.

42.

Gait cycle analysis: parameters sensitive for functional evaluation of peripheral nerve recovery in rat hind limbs.

Rui J, Runge MB, Spinner RJ, Yaszemski MJ, Windebank AJ, Wang H.

Ann Plast Surg. 2014 Oct;73(4):405-11. doi: 10.1097/SAP.0000000000000008.

PMID:
24317246
43.

Bortezomib alters microtubule polymerization and axonal transport in rat dorsal root ganglion neurons.

Staff NP, Podratz JL, Grassner L, Bader M, Paz J, Knight AM, Loprinzi CL, Trushina E, Windebank AJ.

Neurotoxicology. 2013 Dec;39:124-31. doi: 10.1016/j.neuro.2013.09.001. Epub 2013 Sep 12.

44.

Comparison and characterization of multiple biomaterial conduits for peripheral nerve repair.

Daly WT, Knight AM, Wang H, de Boer R, Giusti G, Dadsetan M, Spinner RJ, Yaszemski MJ, Windebank AJ.

Biomaterials. 2013 Nov;34(34):8630-9. doi: 10.1016/j.biomaterials.2013.07.086. Epub 2013 Aug 12.

PMID:
23937914
45.

Improved axonal regeneration of transected spinal cord mediated by multichannel collagen conduits functionalized with neurotrophin-3 gene.

Yao L, Daly W, Newland B, Yao S, Wang W, Chen BK, Madigan N, Windebank A, Pandit A.

Gene Ther. 2013 Dec;20(12):1149-57. doi: 10.1038/gt.2013.42. Epub 2013 Jul 25.

PMID:
23883961
46.

An automated climbing apparatus to measure chemotherapy-induced neurotoxicity in Drosophila melanogaster.

Podratz JL, Staff NP, Boesche JB, Giorno NJ, Hainy ME, Herring SA, Klennert MT, Milaster C, Nowakowski SE, Krug RG 2nd, Peng Y, Windebank AJ.

Fly (Austin). 2013 Jul-Sep;7(3):187-92. doi: 10.4161/fly.24789. Epub 2013 May 21.

47.

The regulation of apoptosis by the downstream regulatory element antagonist modulator/potassium channel interacting protein 3 (DREAM/KChIP3) through interactions with hexokinase I.

Craig TA, Ramachandran PL, Bergen HR 3rd, Podratz JL, Windebank AJ, Kumar R.

Biochem Biophys Res Commun. 2013 Apr 19;433(4):508-12. doi: 10.1016/j.bbrc.2013.03.016. Epub 2013 Mar 21.

48.

A novel and selective poly (ADP-ribose) polymerase inhibitor ameliorates chemotherapy-induced painful neuropathy.

Ta LE, Schmelzer JD, Bieber AJ, Loprinzi CL, Sieck GC, Brederson JD, Low PA, Windebank AJ.

PLoS One. 2013;8(1):e54161. doi: 10.1371/journal.pone.0054161. Epub 2013 Jan 10.

49.

Delayed repair of the peripheral nerve: a novel model in the rat sciatic nerve.

Wu P, Spinner RJ, Gu Y, Yaszemski MJ, Windebank AJ, Wang H.

J Neurosci Methods. 2013 Mar 30;214(1):37-44. doi: 10.1016/j.jneumeth.2013.01.003. Epub 2013 Jan 11.

PMID:
23313757
50.

Comprehensive Method for Culturing Embryonic Dorsal Root Ganglion Neurons for Seahorse Extracellular Flux XF24 Analysis.

Lange M, Zeng Y, Knight A, Windebank A, Trushina E.

Front Neurol. 2012 Dec 14;3:175. doi: 10.3389/fneur.2012.00175. eCollection 2012.

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