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Items: 33


The male mosquito contribution towards malaria transmission: Mating influences the Anopheles female midgut transcriptome and increases female susceptibility to human malaria parasites.

Dahalan FA, Churcher TS, Windbichler N, Lawniczak MKN.

PLoS Pathog. 2019 Nov 7;15(11):e1008063. doi: 10.1371/journal.ppat.1008063. eCollection 2019 Nov.


Gene Drives: Dynamics and Regulatory Matters-A Report from the Workshop "Evaluation of Spatial and Temporal Control of Gene Drives," April 4-5, 2019, Vienna.

Giese B, Frieß JL, Barton NH, Messer PW, Débarre F, Schetelig MF, Windbichler N, Meimberg H, Boëte C.

Bioessays. 2019 Nov;41(11):e1900151. doi: 10.1002/bies.201900151. Epub 2019 Oct 7. No abstract available.


Maleness-on-the-Y (MoY) orchestrates male sex determination in major agricultural fruit fly pests.

Meccariello A, Salvemini M, Primo P, Hall B, Koskinioti P, Dalíková M, Gravina A, Gucciardino MA, Forlenza F, Gregoriou ME, Ippolito D, Monti SM, Petrella V, Perrotta MM, Schmeing S, Ruggiero A, Scolari F, Giordano E, Tsoumani KT, Marec F, Windbichler N, Arunkumar KP, Bourtzis K, Mathiopoulos KD, Ragoussis J, Vitagliano L, Tu Z, Papathanos PA, Robinson MD, Saccone G.

Science. 2019 Sep 27;365(6460):1457-1460. doi: 10.1126/science.aax1318. Epub 2019 Aug 29.


Streamlined SMFA and mosquito dark-feeding regime significantly improve malaria transmission-blocking assay robustness and sensitivity.

Habtewold T, Tapanelli S, Masters EKG, Hoermann A, Windbichler N, Christophides GK.

Malar J. 2019 Jan 25;18(1):24. doi: 10.1186/s12936-019-2663-8.


Integral gene drives for population replacement.

Nash A, Urdaneta GM, Beaghton AK, Hoermann A, Papathanos PA, Christophides GK, Windbichler N.

Biol Open. 2019 Jan 3;8(1). pii: bio037762. doi: 10.1242/bio.037762.


Rationally-engineered reproductive barriers using CRISPR & CRISPRa: an evaluation of the synthetic species concept in Drosophila melanogaster.

Waters AJ, Capriotti P, Gaboriau DCA, Papathanos PA, Windbichler N.

Sci Rep. 2018 Sep 3;8(1):13125. doi: 10.1038/s41598-018-31433-2.


Cross-Species Y Chromosome Function Between Malaria Vectors of the Anopheles gambiae Species Complex.

Bernardini F, Galizi R, Wunderlich M, Taxiarchi C, Kranjc N, Kyrou K, Hammond A, Nolan T, Lawniczak MNK, Papathanos PA, Crisanti A, Windbichler N.

Genetics. 2017 Oct;207(2):729-740. doi: 10.1534/genetics.117.300221. Epub 2017 Aug 31.


Rapid evolution of female-biased genes among four species of Anopheles malaria mosquitoes.

Papa F, Windbichler N, Waterhouse RM, Cagnetti A, D'Amato R, Persampieri T, Lawniczak MKN, Nolan T, Papathanos PA.

Genome Res. 2017 Sep;27(9):1536-1548. doi: 10.1101/gr.217216.116. Epub 2017 Jul 26.


Crystallographic analyses illustrate significant plasticity and efficient recoding of meganuclease target specificity.

Werther R, Hallinan JP, Lambert AR, Havens K, Pogson M, Jarjour J, Galizi R, Windbichler N, Crisanti A, Nolan T, Stoddard BL.

Nucleic Acids Res. 2017 Aug 21;45(14):8621-8634. doi: 10.1093/nar/gkx544.


A CRISPR-Cas9 sex-ratio distortion system for genetic control.

Galizi R, Hammond A, Kyrou K, Taxiarchi C, Bernardini F, O'Loughlin SM, Papathanos PA, Nolan T, Windbichler N, Crisanti A.

Sci Rep. 2016 Aug 3;6:31139. doi: 10.1038/srep31139.


Radical remodeling of the Y chromosome in a recent radiation of malaria mosquitoes.

Hall AB, Papathanos PA, Sharma A, Cheng C, Akbari OS, Assour L, Bergman NH, Cagnetti A, Crisanti A, Dottorini T, Fiorentini E, Galizi R, Hnath J, Jiang X, Koren S, Nolan T, Radune D, Sharakhova MV, Steele A, Timoshevskiy VA, Windbichler N, Zhang S, Hahn MW, Phillippy AM, Emrich SJ, Sharakhov IV, Tu ZJ, Besansky NJ.

Proc Natl Acad Sci U S A. 2016 Apr 12;113(15):E2114-23. doi: 10.1073/pnas.1525164113. Epub 2016 Mar 29.


A CRISPR-Cas9 gene drive system targeting female reproduction in the malaria mosquito vector Anopheles gambiae.

Hammond A, Galizi R, Kyrou K, Simoni A, Siniscalchi C, Katsanos D, Gribble M, Baker D, Marois E, Russell S, Burt A, Windbichler N, Crisanti A, Nolan T.

Nat Biotechnol. 2016 Jan;34(1):78-83. doi: 10.1038/nbt.3439. Epub 2015 Dec 7.


A draft genome sequence of an invasive mosquito: an Italian Aedes albopictus.

Dritsou V, Topalis P, Windbichler N, Simoni A, Hall A, Lawson D, Hinsley M, Hughes D, Napolioni V, Crucianelli F, Deligianni E, Gasperi G, Gomulski LM, Savini G, Manni M, Scolari F, Malacrida AR, Arcà B, Ribeiro JM, Lombardo F, Saccone G, Salvemini M, Moretti R, Aprea G, Calvitti M, Picciolini M, Papathanos PA, Spaccapelo R, Favia G, Crisanti A, Louis C.

Pathog Glob Health. 2015 Jul;109(5):207-20. doi: 10.1179/2047773215Y.0000000031. Epub 2015 Sep 14.


Tools for Anopheles gambiae Transgenesis.

Volohonsky G, Terenzi O, Soichot J, Naujoks DA, Nolan T, Windbichler N, Kapps D, Smidler AL, Vittu A, Costa G, Steinert S, Levashina EA, Blandin SA, Marois E.

G3 (Bethesda). 2015 Apr 13;5(6):1151-63. doi: 10.1534/g3.115.016808.


Development of synthetic selfish elements based on modular nucleases in Drosophila melanogaster.

Simoni A, Siniscalchi C, Chan YS, Huen DS, Russell S, Windbichler N, Crisanti A.

Nucleic Acids Res. 2015 Mar 11;43(5):2991. doi: 10.1093/nar/gkv117. Epub 2015 Feb 11. No abstract available.


A synthetic sex ratio distortion system for the control of the human malaria mosquito.

Galizi R, Doyle LA, Menichelli M, Bernardini F, Deredec A, Burt A, Stoddard BL, Windbichler N, Crisanti A.

Nat Commun. 2014 Jun 10;5:3977. doi: 10.1038/ncomms4977.


Site-specific genetic engineering of the Anopheles gambiae Y chromosome.

Bernardini F, Galizi R, Menichelli M, Papathanos PA, Dritsou V, Marois E, Crisanti A, Windbichler N.

Proc Natl Acad Sci U S A. 2014 May 27;111(21):7600-5. doi: 10.1073/pnas.1404996111. Epub 2014 May 12.


Development of synthetic selfish elements based on modular nucleases in Drosophila melanogaster.

Simoni A, Siniscalchi C, Chan YS, Huen DS, Russell S, Windbichler N, Crisanti A.

Nucleic Acids Res. 2014 Jun;42(11):7461-72. doi: 10.1093/nar/gku387. Epub 2014 May 6. Erratum in: Nucleic Acids Res. 2015 Mar 11;43(5):2991.


Demasculinization of the Anopheles gambiae X chromosome.

Magnusson K, Lycett GJ, Mendes AM, Lynd A, Papathanos PA, Crisanti A, Windbichler N.

BMC Evol Biol. 2012 May 18;12:69. doi: 10.1186/1471-2148-12-69.


Big insights from a small outbreak.

Windbichler N.

Pathog Glob Health. 2012 Mar;106(1):63. doi: 10.1179/204777312X13305103762547. No abstract available.


Infertility resulting from transgenic I-PpoI male Anopheles gambiae in large cage trials.

Klein TA, Windbichler N, Deredec A, Burt A, Benedict MQ.

Pathog Glob Health. 2012 Mar;106(1):20-31. doi: 10.1179/2047773212Y.0000000003.


Transcription regulation of sex-biased genes during ontogeny in the malaria vector Anopheles gambiae.

Magnusson K, Mendes AM, Windbichler N, Papathanos PA, Nolan T, Dottorini T, Rizzi E, Christophides GK, Crisanti A.

PLoS One. 2011;6(6):e21572. doi: 10.1371/journal.pone.0021572. Epub 2011 Jun 30.


A synthetic homing endonuclease-based gene drive system in the human malaria mosquito.

Windbichler N, Menichelli M, Papathanos PA, Thyme SB, Li H, Ulge UY, Hovde BT, Baker D, Monnat RJ Jr, Burt A, Crisanti A.

Nature. 2011 May 12;473(7346):212-5. doi: 10.1038/nature09937. Epub 2011 Apr 20.


Developing transgenic Anopheles mosquitoes for the sterile insect technique.

Nolan T, Papathanos P, Windbichler N, Magnusson K, Benton J, Catteruccia F, Crisanti A.

Genetica. 2011 Jan;139(1):33-9. doi: 10.1007/s10709-010-9482-8. Epub 2010 Sep 7. Review.


Targeting the X chromosome during spermatogenesis induces Y chromosome transmission ratio distortion and early dominant embryo lethality in Anopheles gambiae.

Windbichler N, Papathanos PA, Crisanti A.

PLoS Genet. 2008 Dec;4(12):e1000291. doi: 10.1371/journal.pgen.1000291. Epub 2008 Dec 5.


Isolation of small RNA-binding proteins from E. coli: evidence for frequent interaction of RNAs with RNA polymerase.

Windbichler N, von Pelchrzim F, Mayer O, Csaszar E, Schroeder R.

RNA Biol. 2008 Jan-Mar;5(1):30-40. Epub 2008 Feb 4.


Homing endonuclease mediated gene targeting in Anopheles gambiae cells and embryos.

Windbichler N, Papathanos PA, Catteruccia F, Ranson H, Burt A, Crisanti A.

Nucleic Acids Res. 2007;35(17):5922-33. Epub 2007 Aug 28.


Isolation of specific RNA-binding proteins using the streptomycin-binding RNA aptamer.

Windbichler N, Schroeder R.

Nat Protoc. 2006;1(2):637-40.


Enhancement of the StreptoTag method for isolation of endogenously expressed proteins with complex RNA binding targets.

Dangerfield JA, Windbichler N, Salmons B, Günzburg WH, Schröder R.

Electrophoresis. 2006 May;27(10):1874-7.


Double duty.

Windbichler N, Schroeder R.

Nat Struct Mol Biol. 2004 Oct;11(10):910-1. No abstract available.


Kissing complex-mediated dimerisation of HIV-1 RNA: coupling extended duplex formation to ribozyme cleavage.

Windbichler N, Werner M, Schroeder R.

Nucleic Acids Res. 2003 Nov 15;31(22):6419-27.

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