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Items: 26


Reticular dysgenesis-associated AK2 protects hematopoietic stem and progenitor cell development from oxidative stress.

Rissone A, Weinacht KG, la Marca G, Bishop K, Giocaliere E, Jagadeesh J, Felgentreff K, Dobbs K, Al-Herz W, Jones M, Chandrasekharappa S, Kirby M, Wincovitch S, Simon KL, Itan Y, DeVine A, Schlaeger T, Schambach A, Sood R, Notarangelo LD, Candotti F.

J Exp Med. 2015 Jul 27;212(8):1185-202. doi: 10.1084/jem.20141286. Epub 2015 Jul 6.


Rescue of an in vitro neuron phenotype identified in Niemann-Pick disease, type C1 induced pluripotent stem cell-derived neurons by modulating the WNT pathway and calcium signaling.

Efthymiou AG, Steiner J, Pavan WJ, Wincovitch S, Larson DM, Porter FD, Rao MS, Malik N.

Stem Cells Transl Med. 2015 Mar;4(3):230-8. doi: 10.5966/sctm.2014-0127. Epub 2015 Jan 30.


The Abl/enabled signaling pathway regulates Golgi architecture in Drosophila photoreceptor neurons.

Kannan R, Kuzina I, Wincovitch S, Nowotarski SH, Giniger E.

Mol Biol Cell. 2014 Oct 1;25(19):2993-3005. doi: 10.1091/mbc.E14-02-0729. Epub 2014 Aug 7.


CBFβ and RUNX1 are required at 2 different steps during the development of hematopoietic stem cells in zebrafish.

Bresciani E, Carrington B, Wincovitch S, Jones M, Gore AV, Weinstein BM, Sood R, Liu PP.

Blood. 2014 Jul 3;124(1):70-8. doi: 10.1182/blood-2013-10-531988. Epub 2014 May 21.


Incomplete splicing, cell division defects, and hematopoietic blockage in dhx8 mutant zebrafish.

English MA, Lei L, Blake T, Wincovitch SM Sr, Sood R, Azuma M, Hickstein D, Liu PP.

Dev Dyn. 2012 May;241(5):879-89. doi: 10.1002/dvdy.23774. Epub 2012 Mar 29.


Cellular characterisation of the GCKR P446L variant associated with type 2 diabetes risk.

Rees MG, Wincovitch S, Schultz J, Waterstradt R, Beer NL, Baltrusch S, Collins FS, Gloyn AL.

Diabetologia. 2012 Jan;55(1):114-22. doi: 10.1007/s00125-011-2348-5. Epub 2011 Oct 25.


Sorting nexin 27 protein regulates trafficking of a p21-activated kinase (PAK) interacting exchange factor (β-Pix)-G protein-coupled receptor kinase interacting protein (GIT) complex via a PDZ domain interaction.

Valdes JL, Tang J, McDermott MI, Kuo JC, Zimmerman SP, Wincovitch SM, Waterman CM, Milgram SL, Playford MP.

J Biol Chem. 2011 Nov 11;286(45):39403-16. doi: 10.1074/jbc.M111.260802. Epub 2011 Sep 18.


Genome-wide ChIP-Seq reveals a dramatic shift in the binding of the transcription factor erythroid Kruppel-like factor during erythrocyte differentiation.

Pilon AM, Ajay SS, Kumar SA, Steiner LA, Cherukuri PF, Wincovitch S, Anderson SM; NISC Comparative Sequencing Center, Mullikin JC, Gallagher PG, Hardison RC, Margulies EH, Bodine DM.

Blood. 2011 Oct 27;118(17):e139-48. doi: 10.1182/blood-2011-05-355107. Epub 2011 Sep 6.


Nuclear bud formation: a novel manifestation of Zidovudine genotoxicity.

Dutra A, Pak E, Wincovitch S, John K, Poirier MC, Olivero OA.

Cytogenet Genome Res. 2010;128(1-3):105-10. doi: 10.1159/000298794. Epub 2010 Apr 20.


DNA damage responses by human ELG1 in S phase are important to maintain genomic integrity.

Sikdar N, Banerjee S, Lee KY, Wincovitch S, Pak E, Nakanishi K, Jasin M, Dutra A, Myung K.

Cell Cycle. 2009 Oct 1;8(19):3199-207. Epub 2009 Oct 7.


The interaction of NSBP1/HMGN5 with nucleosomes in euchromatin counteracts linker histone-mediated chromatin compaction and modulates transcription.

Rochman M, Postnikov Y, Correll S, Malicet C, Wincovitch S, Karpova TS, McNally JG, Wu X, Bubunenko NA, Grigoryev S, Bustin M.

Mol Cell. 2009 Sep 11;35(5):642-56. doi: 10.1016/j.molcel.2009.07.002.


CARP-2 is an endosome-associated ubiquitin ligase for RIP and regulates TNF-induced NF-kappaB activation.

Liao W, Xiao Q, Tchikov V, Fujita K, Yang W, Wincovitch S, Garfield S, Conze D, El-Deiry WS, Schütze S, Srinivasula SM.

Curr Biol. 2008 May 6;18(9):641-9. doi: 10.1016/j.cub.2008.04.017.


Requirement for the budding yeast polo kinase Cdc5 in proper microtubule growth and dynamics.

Park CJ, Park JE, Karpova TS, Soung NK, Yu LR, Song S, Lee KH, Xia X, Kang E, Dabanoglu I, Oh DY, Zhang JY, Kang YH, Wincovitch S, Huffaker TC, Veenstra TD, McNally JG, Lee KS.

Eukaryot Cell. 2008 Mar;7(3):444-53. doi: 10.1128/EC.00283-07. Epub 2008 Jan 4.


Human ABCB6 localizes to both the outer mitochondrial membrane and the plasma membrane.

Paterson JK, Shukla S, Black CM, Tachiwada T, Garfield S, Wincovitch S, Ernst DN, Agadir A, Li X, Ambudkar SV, Szakacs G, Akiyama S, Gottesman MM.

Biochemistry. 2007 Aug 21;46(33):9443-52. Epub 2007 Jul 28.


Artificially introduced aneuploid chromosomes assume a conserved position in colon cancer cells.

Sengupta K, Upender MB, Barenboim-Stapleton L, Nguyen QT, Wincovitch SM Sr, Garfield SH, Difilippantonio MJ, Ried T.

PLoS One. 2007 Feb 7;2(2):e199.


Conformationally constrained analogues of diacylglycerol (DAG). 27. Modulation of membrane translocation of protein kinase C (PKC) isozymes alpha and delta by diacylglycerol lactones (DAG-lactones) containing rigid-rod acyl groups.

Malolanarasimhan K, Kedei N, Sigano DM, Kelley JA, Lai CC, Lewin NE, Surawski RJ, Pavlyukovets VA, Garfield SH, Wincovitch S, Blumberg PM, Marquez VE.

J Med Chem. 2007 Mar 8;50(5):962-78. Epub 2007 Feb 7.


Multispectral imaging of clinically relevant cellular targets in tonsil and lymphoid tissue using semiconductor quantum dots.

Fountaine TJ, Wincovitch SM, Geho DH, Garfield SH, Pittaluga S.

Mod Pathol. 2006 Sep;19(9):1181-91. Epub 2006 Jun 16.


Melanosomal sequestration of cytotoxic drugs contributes to the intractability of malignant melanomas.

Chen KG, Valencia JC, Lai B, Zhang G, Paterson JK, Rouzaud F, Berens W, Wincovitch SM, Garfield SH, Leapman RD, Hearing VJ, Gottesman MM.

Proc Natl Acad Sci U S A. 2006 Jun 27;103(26):9903-7. Epub 2006 Jun 15.


Structural and molecular hair abnormalities in trichothiodystrophy.

Liang C, Morris A, Schlücker S, Imoto K, Price VH, Menefee E, Wincovitch SM, Levin IW, Tamura D, Strehle KR, Kraemer KH, DiGiovanna JJ.

J Invest Dermatol. 2006 Oct;126(10):2210-6. Epub 2006 May 25.


Kinetics of penetration influence the apparent potency of vanilloids on TRPV1.

Lazar J, Braun DC, Tóth A, Wang Y, Pearce LV, Pavlyukovets VA, Blumberg PM, Garfield SH, Wincovitch S, Choi HK, Lee J.

Mol Pharmacol. 2006 Apr;69(4):1166-73. Epub 2006 Jan 17.


Different roles for K+ channels in cisplatin-resistant cell lines argue against a critical role for these channels in cisplatin resistance.

Liang XJ, Taylor B, Cardarelli C, Yin JJ, Annereau JP, Garfield S, Wincovitch S, Szakács G, Gottesman MM, Aszalos A.

Anticancer Res. 2005 Nov-Dec;25(6B):4113-22.


Grading melanocytic dysplasia in paraffin wax embedded tissue by the nucleic acid index.

Berman DM, Wincovitch S, Garfield S, Romeo MJ.

J Clin Pathol. 2005 Nov;58(11):1206-10.


ING2 regulates the onset of replicative senescence by induction of p300-dependent p53 acetylation.

Pedeux R, Sengupta S, Shen JC, Demidov ON, Saito S, Onogi H, Kumamoto K, Wincovitch S, Garfield SH, McMenamin M, Nagashima M, Grossman SR, Appella E, Harris CC.

Mol Cell Biol. 2005 Aug;25(15):6639-48.


A quantitative determination of multi-protein interactions by the analysis of confocal images using a pixel-by-pixel assessment algorithm.

Goucher DR, Wincovitch SM, Garfield SH, Carbone KM, Malik TH.

Bioinformatics. 2005 Aug 1;21(15):3248-54. Epub 2005 Jun 9.


Trafficking and localization of platinum complexes in cisplatin-resistant cell lines monitored by fluorescence-labeled platinum.

Liang XJ, Shen DW, Chen KG, Wincovitch SM, Garfield SH, Gottesman MM.

J Cell Physiol. 2005 Mar;202(3):635-41.


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