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The Thriving of Older People Assessment Scale: Psychometric evaluation and short-form development.

Baxter R, Lövheim H, Björk S, Sköldunger A, Lindkvist M, Sjögren K, Sandman PO, Bergland Å, Winblad B, Edvardsson D.

J Adv Nurs. 2019 Aug 23. doi: 10.1111/jan.14180. [Epub ahead of print]


Assessing cost-effectiveness of early intervention in Alzheimer's disease: An open-source modeling framework.

Green C, Handels R, Gustavsson A, Wimo A, Winblad B, Sköldunger A, Jönsson L.

Alzheimers Dement. 2019 Aug 8. pii: S1552-5260(19)30139-6. doi: 10.1016/j.jalz.2019.05.004. [Epub ahead of print]


Current and emerging avenues for Alzheimer's disease drug targets.

Loera-Valencia R, Cedazo-Minguez A, Kenigsberg P, Page G, Duarte A, Giusti P, Zusso M, Robert P, Frisoni GB, Cattaneo A, Zille M, Boltze J, Cartier N, Buee L, Johansson G, Winblad B.

J Intern Med. 2019 Jul 8. doi: 10.1111/joim.12959. [Epub ahead of print] Review.


Head trauma in sports and risk for dementia.

Winblad B, Ankarcrona M, Johansson G, Novak P, Peter Thelin E, Zetterberg H, Blennow K.

J Intern Med. 2019 Jun;285(6):591-593. doi: 10.1111/joim.12918. Epub 2019 May 15. No abstract available.


The MOPEAD project: Advancing patient engagement for the detection of "hidden" undiagnosed cases of Alzheimer's disease in the community.

Rodríguez-Gómez O, Rodrigo A, Iradier F, Santos-Santos MA, Hundemer H, Ciudin A, Sannemann L, Zwan M, Glaysher B, Wimo A, Bonn J, Johansson G, Rodriguez I, Alegret M, Gove D, Pinó S, Trigueros P, Kivipelto M, Mathews B, Ciudad A, Ferreira D, Bintener C, Gurruchaga M, Westman E, Belger M, Valero S, Maguire P, Krivec D, Kramberger M, Simó R, Garro IP, Visser PJ, Dumas A, Georges J, Jessen F, Winblad B, Shering C, Stewart N, Campo L, Boada M; MOPEAD Consortium.

Alzheimers Dement. 2019 Jun;15(6):828-839. doi: 10.1016/j.jalz.2019.02.003. Epub 2019 May 7. Review.


Antipsychotic Treatment Associated With Increased Mortality Risk in Patients With Dementia. A Registry-Based Observational Cohort Study.

Schwertner E, Secnik J, Garcia-Ptacek S, Johansson B, Nagga K, Eriksdotter M, Winblad B, Religa D.

J Am Med Dir Assoc. 2019 Mar;20(3):323-329.e2. doi: 10.1016/j.jamda.2018.12.019.


Residing in sheltered housing versus ageing in place - Population characteristics, health status and social participation.

Corneliusson L, Sköldunger A, Sjögren K, Lövheim H, Wimo A, Winblad B, Sandman PO, Edvardsson D.

Health Soc Care Community. 2019 Jul;27(4):e313-e322. doi: 10.1111/hsc.12734. Epub 2019 Mar 1.


Conformation-specific antibodies against multiple amyloid protofibril species from a single amyloid immunogen.

Bonito-Oliva A, Schedin-Weiss S, Younesi SS, Tiiman A, Adura C, Paknejad N, Brendel M, Romin Y, Parchem RJ, Graff C, Vukojević V, Tjernberg LO, Terenius L, Winblad B, Sakmar TP, Graham WV.

J Cell Mol Med. 2019 Mar;23(3):2103-2114. doi: 10.1111/jcmm.14119. Epub 2019 Jan 20.


Phenotypic variability and neuropsychological findings associated with C9orf72 repeat expansions in a Bulgarian dementia cohort.

Mehrabian S, Thonberg H, Raycheva M, Lilius L, Stoyanova K, Forsell C, Cavallin L, Nesheva D, Westman E, Toncheva D, Traykov L, Winblad B, Graff C.

PLoS One. 2018 Dec 14;13(12):e0208383. doi: 10.1371/journal.pone.0208383. eCollection 2018.


Head trauma in sports - clinical characteristics, epidemiology and biomarkers.

Zetterberg H, Winblad B, Bernick C, Yaffe K, Majdan M, Johansson G, Newcombe V, Nyberg L, Sharp D, Tenovuo O, Blennow K.

J Intern Med. 2019 Jun;285(6):624-634. doi: 10.1111/joim.12863. Epub 2018 Dec 18.


The Bri2 and Bri3 BRICHOS Domains Interact Differently with Aβ42 and Alzheimer Amyloid Plaques.

Dolfe L, Tambaro S, Tigro H, Del Campo M, Hoozemans JJM, Wiehager B, Graff C, Winblad B, Ankarcrona M, Kaldmäe M, Teunissen CE, Rönnbäck A, Johansson J, Presto J.

J Alzheimers Dis Rep. 2018 Feb 16;2(1):27-39. doi: 10.3233/ADR-170051.


Neuronal Aβ42 is enriched in small vesicles at the presynaptic side of synapses.

Yu Y, Jans DC, Winblad B, Tjernberg LO, Schedin-Weiss S.

Life Sci Alliance. 2018 Jun 14;1(3):e201800028. doi: 10.26508/lsa.201800028. eCollection 2018 Jun.


In silico identification and biochemical characterization of the human dicarboxylate clamp TPR protein interaction network.

Bernadotte A, Kumar R, Winblad B, Pavlov PF.

FEBS Open Bio. 2018 Oct 9;8(11):1830-1843. doi: 10.1002/2211-5463.12521. eCollection 2018 Nov.


Autophagy-lysosomal defect in human CADASIL vascular smooth muscle cells.

Hanemaaijer ES, Panahi M, Swaddiwudhipong N, Tikka S, Winblad B, Viitanen M, Piras A, Behbahani H.

Eur J Cell Biol. 2018 Nov;97(8):557-567. doi: 10.1016/j.ejcb.2018.10.001. Epub 2018 Oct 22.


Increased Active OMI/HTRA2 Serine Protease Displays a Positive Correlation with Cholinergic Alterations in the Alzheimer's Disease Brain.

Darreh-Shori T, Rezaeianyazdi S, Lana E, Mitra S, Gellerbring A, Karami A, Bogdanovic N, Lithner CU, Winblad B, Behbahani H.

Mol Neurobiol. 2019 Jul;56(7):4601-4619. doi: 10.1007/s12035-018-1383-3. Epub 2018 Oct 25.


FUNDAMANT: an interventional 72-week phase 1 follow-up study of AADvac1, an active immunotherapy against tau protein pathology in Alzheimer's disease.

Novak P, Schmidt R, Kontsekova E, Kovacech B, Smolek T, Katina S, Fialova L, Prcina M, Parrak V, Dal-Bianco P, Brunner M, Staffen W, Rainer M, Ondrus M, Ropele S, Smisek M, Sivak R, Zilka N, Winblad B, Novak M.

Alzheimers Res Ther. 2018 Oct 24;10(1):108. doi: 10.1186/s13195-018-0436-1.


Stroke as a Cause of Death in Death Certificates of Patients with Dementia: A Cohort Study from the Swedish Dementia Registry.

Subic A, Zupanic E, von Euler M, Norrving B, Cermakova P, Religa D, Winblad B, Kramberger MG, Eriksdotter M, Garcia-Ptacek S.

Curr Alzheimer Res. 2018;15(14):1322-1330. doi: 10.2174/1567205015666181002134155.


Connecting the brain cholesterol and renin-angiotensin systems: potential role of statins and RAS-modifying medications in dementia.

Petek B, Villa-Lopez M, Loera-Valencia R, Gerenu G, Winblad B, Kramberger MG, Ismail MA, Eriksdotter M, Garcia-Ptacek S.

J Intern Med. 2018 Dec;284(6):620-642. doi: 10.1111/joim.12838. Epub 2018 Oct 28. Review.


Acute Stroke Care in Dementia: A Cohort Study from the Swedish Dementia and Stroke Registries.

Zupanic E, Kåreholt I, Norrving B, Secnik J, von Euler M, Winblad B, Religa D, Kramberger MG, Johnell K, Eriksdotter M, Garcia-Ptacek S.

J Alzheimers Dis. 2018;66(1):185-194. doi: 10.3233/JAD-180653.


Development of GMP-1 a molecular chaperone network modulator protecting mitochondrial function and its assessment in fly and mice models of Alzheimer's disease.

Pavlov PF, Hutter-Paier B, Havas D, Windisch M, Winblad B.

J Cell Mol Med. 2018 Jul;22(7):3464-3474. doi: 10.1111/jcmm.13624. Epub 2018 Apr 27.


Targeting Alzheimer's disease with gene and cell therapies.

Loera-Valencia R, Piras A, Ismail MAM, Manchanda S, Eyjolfsdottir H, Saido TC, Johansson J, Eriksdotter M, Winblad B, Nilsson P.

J Intern Med. 2018 Jul;284(1):2-36. doi: 10.1111/joim.12759. Review.


Apolipoprotein E genotypes and longevity across dementia disorders.

Skillbäck T, Lautner R, Mattsson N, Schott JM, Skoog I, Nägga K, Kilander L, Wimo A, Winblad B, Eriksdotter M, Blennow K, Zetterberg H.

Alzheimers Dement. 2018 Jul;14(7):895-901. doi: 10.1016/j.jalz.2018.02.003. Epub 2018 Mar 13.


Differences in proliferation rate between CADASIL and control vascular smooth muscle cells are related to increased TGFβ expression.

Panahi M, Yousefi Mesri N, Samuelsson EB, Coupland KG, Forsell C, Graff C, Tikka S, Winblad B, Viitanen M, Karlström H, Sundström E, Behbahani H.

J Cell Mol Med. 2018 Jun;22(6):3016-3024. doi: 10.1111/jcmm.13534. Epub 2018 Mar 13.


Longitudinal relationships among depressive symptoms, cortisol, and brain atrophy in the neocortex and the hippocampus.

Lebedeva A, Sundström A, Lindgren L, Stomby A, Aarsland D, Westman E, Winblad B, Olsson T, Nyberg L.

Acta Psychiatr Scand. 2018 Jun;137(6):491-502. doi: 10.1111/acps.12860. Epub 2018 Feb 18.


Synaptic markers of cognitive decline in neurodegenerative diseases: a proteomic approach.

Bereczki E, Branca RM, Francis PT, Pereira JB, Baek JH, Hortobágyi T, Winblad B, Ballard C, Lehtiö J, Aarsland D.

Brain. 2018 Feb 1;141(2):582-595. doi: 10.1093/brain/awx352. Erratum in: Brain. 2019 Jun 1;142(6):e24.


Treatment of Atrial Fibrillation in Patients with Dementia: A Cohort Study from the Swedish Dementia Registry.

Subic A, Cermakova P, Religa D, Han S, von Euler M, Kåreholt I, Johnell K, Fastbom J, Bognandi L, Winblad B, Kramberger MG, Eriksdotter M, Garcia-Ptacek S.

J Alzheimers Dis. 2018;61(3):1119-1128. doi: 10.3233/JAD-170575.


Quantitative EEG power and synchronization correlate with Alzheimer's disease CSF biomarkers.

Smailovic U, Koenig T, Kåreholt I, Andersson T, Kramberger MG, Winblad B, Jelic V.

Neurobiol Aging. 2018 Mar;63:88-95. doi: 10.1016/j.neurobiolaging.2017.11.005. Epub 2017 Nov 16.


Cost-Utility of Using Alzheimer's Disease Biomarkers in Cerebrospinal Fluid to Predict Progression from Mild Cognitive Impairment to Dementia.

Handels RLH, Wimo A, Dodel R, Kramberger MG, Visser PJ, Molinuevo JL, Verhey FRJ, Winblad B.

J Alzheimers Dis. 2017;60(4):1477-1487. doi: 10.3233/JAD-170324.


Combined x-ray crystallography and computational modeling approach to investigate the Hsp90 C-terminal peptide binding to FKBP51.

Kumar R, Moche M, Winblad B, Pavlov PF.

Sci Rep. 2017 Oct 27;7(1):14288. doi: 10.1038/s41598-017-14731-z.


Cerebrospinal fluid and blood biomarkers for neurodegenerative dementias: An update of the Consensus of the Task Force on Biological Markers in Psychiatry of the World Federation of Societies of Biological Psychiatry.

Lewczuk P, Riederer P, O'Bryant SE, Verbeek MM, Dubois B, Visser PJ, Jellinger KA, Engelborghs S, Ramirez A, Parnetti L, Jack CR Jr, Teunissen CE, Hampel H, Lleó A, Jessen F, Glodzik L, de Leon MJ, Fagan AM, Molinuevo JL, Jansen WJ, Winblad B, Shaw LM, Andreasson U, Otto M, Mollenhauer B, Wiltfang J, Turner MR, Zerr I, Handels R, Thompson AG, Johansson G, Ermann N, Trojanowski JQ, Karaca I, Wagner H, Oeckl P, van Waalwijk van Doorn L, Bjerke M, Kapogiannis D, Kuiperij HB, Farotti L, Li Y, Gordon BA, Epelbaum S, Vos SJB, Klijn CJM, Van Nostrand WE, Minguillon C, Schmitz M, Gallo C, Lopez Mato A, Thibaut F, Lista S, Alcolea D, Zetterberg H, Blennow K, Kornhuber J; Members of the WFSBP Task Force Working on this Topic: Peter Riederer, Carla Gallo, Dimitrios Kapogiannis, Andrea Lopez Mato, Florence Thibaut.

World J Biol Psychiatry. 2018 Jun;19(4):244-328. doi: 10.1080/15622975.2017.1375556. Epub 2017 Oct 27. Review.


Tau hyperphosphorylation induces oligomeric insulin accumulation and insulin resistance in neurons.

Rodriguez-Rodriguez P, Sandebring-Matton A, Merino-Serrais P, Parrado-Fernandez C, Rabano A, Winblad B, Ávila J, Ferrer I, Cedazo-Minguez A.

Brain. 2017 Dec 1;140(12):3269-3285. doi: 10.1093/brain/awx256. Erratum in: Brain. 2018 May 1;141(5):e43.


Thrombolysis in acute ischemic stroke in patients with dementia: A Swedish registry study.

Zupanic E, von Euler M, Kåreholt I, Contreras Escamez B, Fastbom J, Norrving B, Religa D, Kramberger MG, Winblad B, Johnell K, Eriksdotter M, Garcia-Ptacek S.

Neurology. 2017 Oct 31;89(18):1860-1868. doi: 10.1212/WNL.0000000000004598. Epub 2017 Oct 6.


Current Approaches and Clinician Attitudes to the Use of Cerebrospinal Fluid Biomarkers in Diagnostic Evaluation of Dementia in Europe.

Miller AM, Balasa M, Blennow K, Gardiner M, Rutkowska A, Scheltens P, Teunissen CE, Visser PJ, Winblad B, Waldemar G, Lawlor B.

J Alzheimers Dis. 2017;60(1):201-210. doi: 10.3233/JAD-170502.


CSF/serum albumin ratio in dementias: a cross-sectional study on 1861 patients.

Skillbäck T, Delsing L, Synnergren J, Mattsson N, Janelidze S, Nägga K, Kilander L, Hicks R, Wimo A, Winblad B, Hansson O, Blennow K, Eriksdotter M, Zetterberg H.

Neurobiol Aging. 2017 Nov;59:1-9. doi: 10.1016/j.neurobiolaging.2017.06.028. Epub 2017 Jul 11.


APP mouse models for Alzheimer's disease preclinical studies.

Sasaguri H, Nilsson P, Hashimoto S, Nagata K, Saito T, De Strooper B, Hardy J, Vassar R, Winblad B, Saido TC.

EMBO J. 2017 Sep 1;36(17):2473-2487. doi: 10.15252/embj.201797397. Epub 2017 Aug 1. Review.


Monoamine oxidase B is elevated in Alzheimer disease neurons, is associated with γ-secretase and regulates neuronal amyloid β-peptide levels.

Schedin-Weiss S, Inoue M, Hromadkova L, Teranishi Y, Yamamoto NG, Wiehager B, Bogdanovic N, Winblad B, Sandebring-Matton A, Frykman S, Tjernberg LO.

Alzheimers Res Ther. 2017 Aug 1;9(1):57. doi: 10.1186/s13195-017-0279-1.


Strategic roadmap for an early diagnosis of Alzheimer's disease based on biomarkers.

Frisoni GB, Boccardi M, Barkhof F, Blennow K, Cappa S, Chiotis K, Démonet JF, Garibotto V, Giannakopoulos P, Gietl A, Hansson O, Herholz K, Jack CR Jr, Nobili F, Nordberg A, Snyder HM, Ten Kate M, Varrone A, Albanese E, Becker S, Bossuyt P, Carrillo MC, Cerami C, Dubois B, Gallo V, Giacobini E, Gold G, Hurst S, Lönneborg A, Lovblad KO, Mattsson N, Molinuevo JL, Monsch AU, Mosimann U, Padovani A, Picco A, Porteri C, Ratib O, Saint-Aubert L, Scerri C, Scheltens P, Schott JM, Sonni I, Teipel S, Vineis P, Visser PJ, Yasui Y, Winblad B.

Lancet Neurol. 2017 Aug;16(8):661-676. doi: 10.1016/S1474-4422(17)30159-X. Epub 2017 Jul 11. Review.


Subclinical white matter lesions and medial temporal lobe atrophy are associated with EEG slowing in a memory clinic cohort.

Kramberger MG, Giske K, Cavallin L, Kåreholt I, Andersson T, Winblad B, Jelic V.

Clin Neurophysiol. 2017 Sep;128(9):1575-1582. doi: 10.1016/j.clinph.2017.05.018. Epub 2017 Jun 15.


Diabetes in a Large Dementia Cohort: Clinical Characteristics and Treatment From the Swedish Dementia Registry.

Secnik J, Cermakova P, Fereshtehnejad SM, Dannberg P, Johnell K, Fastbom J, Winblad B, Eriksdotter M, Religa D.

Diabetes Care. 2017 Sep;40(9):1159-1166. doi: 10.2337/dc16-2516. Epub 2017 Jun 27.


Consensus guidelines for lumbar puncture in patients with neurological diseases.

Engelborghs S, Niemantsverdriet E, Struyfs H, Blennow K, Brouns R, Comabella M, Dujmovic I, van der Flier W, Frölich L, Galimberti D, Gnanapavan S, Hemmer B, Hoff E, Hort J, Iacobaeus E, Ingelsson M, Jan de Jong F, Jonsson M, Khalil M, Kuhle J, Lleó A, de Mendonça A, Molinuevo JL, Nagels G, Paquet C, Parnetti L, Roks G, Rosa-Neto P, Scheltens P, Skårsgard C, Stomrud E, Tumani H, Visser PJ, Wallin A, Winblad B, Zetterberg H, Duits F, Teunissen CE.

Alzheimers Dement (Amst). 2017 May 18;8:111-126. doi: 10.1016/j.dadm.2017.04.007. eCollection 2017.


Living Alone with Alzheimer's Disease: Data from SveDem, the Swedish Dementia Registry.

Cermakova P, Nelson M, Secnik J, Garcia-Ptacek S, Johnell K, Fastbom J, Kilander L, Winblad B, Eriksdotter M, Religa D.

J Alzheimers Dis. 2017;58(4):1265-1272. doi: 10.3233/JAD-170102.


Recommendations for cerebrospinal fluid Alzheimer's disease biomarkers in the diagnostic evaluation of mild cognitive impairment.

Herukka SK, Simonsen AH, Andreasen N, Baldeiras I, Bjerke M, Blennow K, Engelborghs S, Frisoni GB, Gabryelewicz T, Galluzzi S, Handels R, Kramberger MG, Kulczyńska A, Molinuevo JL, Mroczko B, Nordberg A, Oliveira CR, Otto M, Rinne JO, Rot U, Saka E, Soininen H, Struyfs H, Suardi S, Visser PJ, Winblad B, Zetterberg H, Waldemar G.

Alzheimers Dement. 2017 Mar;13(3):285-295. doi: 10.1016/j.jalz.2016.09.009. Epub 2016 Oct 27. Review.


Recommendations for CSF AD biomarkers in the diagnostic evaluation of dementia.

Simonsen AH, Herukka SK, Andreasen N, Baldeiras I, Bjerke M, Blennow K, Engelborghs S, Frisoni GB, Gabryelewicz T, Galluzzi S, Handels R, Kramberger MG, Kulczyńska A, Molinuevo JL, Mroczko B, Nordberg A, Oliveira CR, Otto M, Rinne JO, Rot U, Saka E, Soininen H, Struyfs H, Suardi S, Visser PJ, Winblad B, Zetterberg H, Waldemar G.

Alzheimers Dement. 2017 Mar;13(3):274-284. doi: 10.1016/j.jalz.2016.09.008. Epub 2016 Oct 27. Review.


The biomarker-based diagnosis of Alzheimer's disease. 2-lessons from oncology.

Boccardi M, Gallo V, Yasui Y, Vineis P, Padovani A, Mosimann U, Giannakopoulos P, Gold G, Dubois B, Jack CR Jr, Winblad B, Frisoni GB, Albanese E; Geneva Task Force for the Roadmap of Alzheimer's Biomarkers.

Neurobiol Aging. 2017 Apr;52:141-152. doi: 10.1016/j.neurobiolaging.2017.01.021. Review.


The biomarker-based diagnosis of Alzheimer's disease. 1-ethical and societal issues.

Porteri C, Albanese E, Scerri C, Carrillo MC, Snyder HM, Martensson B, Baker M, Giacobini E, Boccardi M, Winblad B, Frisoni GB, Hurst S; Geneva Task Force for the Roadmap of Alzheimer's Biomarkers.

Neurobiol Aging. 2017 Apr;52:132-140. doi: 10.1016/j.neurobiolaging.2016.07.011. Review.


Alzheimer's disease biomarker development: a call to funding bodies.

Frisoni GB, Jack CR Jr, Winblad B.

Neurobiol Aging. 2017 Apr;52:117-118. doi: 10.1016/j.neurobiolaging.2016.02.035. No abstract available.


Long-Term Cognitive Decline in Dementia with Lewy Bodies in a Large Multicenter, International Cohort.

Kramberger MG, Auestad B, Garcia-Ptacek S, Abdelnour C, Olmo JG, Walker Z, Lemstra AW, Londos E, Blanc F, Bonanni L, McKeith I, Winblad B, de Jong FJ, Nobili F, Stefanova E, Petrova M, Falup-Pecurariu C, Rektorova I, Bostantjopoulou S, Biundo R, Weintraub D, Aarsland D; E-DLB.

J Alzheimers Dis. 2017;57(3):787-795. doi: 10.3233/JAD-161109.


Effects of Risperidone and Galantamine Treatment on Alzheimer's Disease Biomarker Levels in Cerebrospinal Fluid.

Bloniecki V, Aarsland D, Blennow K, Cummings J, Falahati F, Winblad B, Freund-Levi Y.

J Alzheimers Dis. 2017;57(2):387-393. doi: 10.3233/JAD-160758.


Predicting progression to dementia in persons with mild cognitive impairment using cerebrospinal fluid markers.

Handels RLH, Vos SJB, Kramberger MG, Jelic V, Blennow K, van Buchem M, van der Flier W, Freund-Levi Y, Hampel H, Olde Rikkert M, Oleksik A, Pirtosek Z, Scheltens P, Soininen H, Teunissen C, Tsolaki M, Wallin AK, Winblad B, Verhey FRJ, Visser PJ.

Alzheimers Dement. 2017 Aug;13(8):903-912. doi: 10.1016/j.jalz.2016.12.015. Epub 2017 Feb 17.


27-Hydroxycholesterol impairs neuronal glucose uptake through an IRAP/GLUT4 system dysregulation.

Ismail MA, Mateos L, Maioli S, Merino-Serrais P, Ali Z, Lodeiro M, Westman E, Leitersdorf E, Gulyás B, Olof-Wahlund L, Winblad B, Savitcheva I, Björkhem I, Cedazo-Mínguez A.

J Exp Med. 2017 Mar 6;214(3):699-717. doi: 10.1084/jem.20160534. Epub 2017 Feb 17.

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