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Items: 1 to 50 of 453

1.

Dengue and Zika Virus 5' Untranslated Regions Harbor Internal Ribosomal Entry Site Functions.

Song Y, Mugavero J, Stauft CB, Wimmer E.

MBio. 2019 Apr 9;10(2). pii: e00459-19. doi: 10.1128/mBio.00459-19.

2.

Fibroblast growth factor receptor 4 single nucleotide polymorphism Gly388Arg in head and neck carcinomas.

Wimmer E, Ihrler S, Gires O, Streit S, Issing W, Bergmann C.

World J Clin Oncol. 2019 Mar 24;10(3):136-148. doi: 10.5306/wjco.v10.i3.136.

3.

Multidisciplinary Tumor Board Recommendations for Oligometastatic Malignancies: A Prospective Single-Center Analysis.

Galata C, Wimmer E, Kasper B, Wenz F, Reißfelder C, Jakob J.

Oncol Res Treat. 2019;42(3):87-94. doi: 10.1159/000495474. Epub 2019 Feb 27.

PMID:
30814474
4.

An Autonomous Self-Optimizing Flow Reactor for the Synthesis of Natural Product Carpanone.

Cortés-Borda D, Wimmer E, Gouilleux B, Barré E, Oger N, Goulamaly L, Peault L, Charrier B, Truchet C, Giraudeau P, Rodriguez-Zubiri M, Le Grognec E, Felpin FX.

J Org Chem. 2018 Dec 7;83(23):14286-14299. doi: 10.1021/acs.joc.8b01821. Epub 2018 Oct 3.

PMID:
30212208
5.

Extensive recoding of dengue virus type 2 specifically reduces replication in primate cells without gain-of-function in Aedes aegypti mosquitoes.

Stauft CB, Shen SH, Song Y, Gorbatsevych O, Asare E, Futcher B, Mueller S, Payne A, Brecher M, Kramer L, Wimmer E.

PLoS One. 2018 Sep 7;13(9):e0198303. doi: 10.1371/journal.pone.0198303. eCollection 2018.

6.

Consequences of resistance evolution in a Cas9-based sex conversion-suppression gene drive for insect pest management.

KaramiNejadRanjbar M, Eckermann KN, Ahmed HMM, Sánchez C HM, Dippel S, Marshall JM, Wimmer EA.

Proc Natl Acad Sci U S A. 2018 Jun 12;115(24):6189-6194. doi: 10.1073/pnas.1713825115. Epub 2018 May 29.

7.

Hyperactive piggyBac transposase improves transformation efficiency in diverse insect species.

Eckermann KN, Ahmed HMM, KaramiNejadRanjbar M, Dippel S, Ogaugwu CE, Kitzmann P, Isah MD, Wimmer EA.

Insect Biochem Mol Biol. 2018 Jul;98:16-24. doi: 10.1016/j.ibmb.2018.04.001. Epub 2018 Apr 10.

PMID:
29653176
8.

[In process].

Wimmer E.

Pflege Z. 2017 Apr;70(4):29-31. German. No abstract available.

PMID:
29425433
9.

Limits of variation, specific infectivity, and genome packaging of massively recoded poliovirus genomes.

Song Y, Gorbatsevych O, Liu Y, Mugavero J, Shen SH, Ward CB, Asare E, Jiang P, Paul AV, Mueller S, Wimmer E.

Proc Natl Acad Sci U S A. 2017 Oct 10;114(41):E8731-E8740. doi: 10.1073/pnas.1714385114. Epub 2017 Sep 25.

10.

Deficits in comprehending wh-questions in children with hearing loss - the contribution of phonological short-term memory and syntactic complexity.

Penke M, Wimmer E.

Clin Linguist Phon. 2018;32(3):267-284. doi: 10.1080/02699206.2017.1350883. Epub 2017 Aug 28.

PMID:
28846461
11.

Acquisition of who-question comprehension in German children with hearing loss.

Wimmer E, Rothweiler M, Penke M.

J Commun Disord. 2017 May;67:35-48. doi: 10.1016/j.jcomdis.2017.05.003. Epub 2017 May 13.

PMID:
28544920
12.

Male sex in houseflies is determined by Mdmd, a paralog of the generic splice factor gene CWC22.

Sharma A, Heinze SD, Wu Y, Kohlbrenner T, Morilla I, Brunner C, Wimmer EA, van de Zande L, Robinson MD, Beukeboom LW, Bopp D.

Science. 2017 May 12;356(6338):642-645. doi: 10.1126/science.aam5498.

PMID:
28495751
13.

Erratum to: The whole genome sequence of the Mediterranean fruit fly, Ceratitis capitata (Wiedemann), reveals insights into the biology and adaptive evolution of a highly invasive pest species.

Papanicolaou A, Schetelig MF, Arensburger P, Atkinson PW, Benoit JB, Bourtzis K, Castañera P, Cavanaugh JP, Chao H, Childers C, Curril I, Dinh H, Doddapaneni H, Dolan A, Dugan S, Friedrich M, Gasperi G, Geib S, Georgakilas G, Gibbs RA, Giers SD, Gomulski LM, González-Guzmán M, Guillem-Amat A, Han Y, Hatzigeorgiou AG, Hernández-Crespo P, Hughes DS, Jones JW, Karagkouni D, Koskinioti P, Lee SL, Malacrida AR, Manni M, Mathiopoulos K, Meccariello A, Munoz-Torres M, Murali SC, Murphy TD, Muzny DM, Oberhofer G, Ortego F, Paraskevopoulou MD, Poelchau M, Qu J, Reczko M, Robertson HM, Rosendale AJ, Rosselot AE, Saccone G, Salvemini M, Savini G, Schreiner P, Scolari F, Siciliano P, Sim SB, Tsiamis G, Ureña E, S Vlachos I, Werren JH, Wimmer EA, Worley KC, Zacharopoulou A, Richards S, Handler AM.

Genome Biol. 2017 Jan 18;18(1):11. doi: 10.1186/s13059-017-1155-9. No abstract available.

14.

Zeolite-Based Organic Synthesis (ZeoBOS) of Acortatarin A: First Total Synthesis Based on Native and Metal-Doped Zeolite-Catalyzed Steps.

Wimmer E, Borghèse S, Blanc A, Bénéteau V, Pale P.

Chemistry. 2017 Jan 31;23(7):1484-1489. doi: 10.1002/chem.201605048. Epub 2017 Jan 16.

PMID:
28090685
15.

Genetic stability of genome-scale deoptimized RNA virus vaccine candidates under selective pressure.

Le Nouën C, McCarty T, Brown M, Smith ML, Lleras R, Dolan MA, Mehedi M, Yang L, Luongo C, Liang B, Munir S, DiNapoli JM, Mueller S, Wimmer E, Collins PL, Buchholz UJ.

Proc Natl Acad Sci U S A. 2017 Jan 17;114(3):E386-E395. doi: 10.1073/pnas.1619242114. Epub 2017 Jan 3.

16.

Understanding Research Impact: A Review of Existing and Emerging Tools for Nursing.

Wimmer EN, Rethlefsen ML, Jarvis C, Shipman JP.

J Prof Nurs. 2016 Nov - Dec;32(6):401-411. doi: 10.1016/j.profnurs.2016.05.005. Epub 2016 May 18. Review.

PMID:
27964810
17.

Metabolism of the MEK1/2 Inhibitor Pimasertib Involves a Novel Conjugation with Phosphoethanolamine in Patients with Solid Tumors.

Scheible H, Kraetzer F, Marx A, Johne A, Wimmer E.

Drug Metab Dispos. 2017 Feb;45(2):174-182. doi: 10.1124/dmd.116.072934. Epub 2016 Dec 1.

PMID:
27934635
18.

Morphological and Transcriptomic Analysis of a Beetle Chemosensory System Reveals a Gnathal Olfactory Center.

Dippel S, Kollmann M, Oberhofer G, Montino A, Knoll C, Krala M, Rexer KH, Frank S, Kumpf R, Schachtner J, Wimmer EA.

BMC Biol. 2016 Oct 17;14(1):90.

19.

The whole genome sequence of the Mediterranean fruit fly, Ceratitis capitata (Wiedemann), reveals insights into the biology and adaptive evolution of a highly invasive pest species.

Papanicolaou A, Schetelig MF, Arensburger P, Atkinson PW, Benoit JB, Bourtzis K, Castañera P, Cavanaugh JP, Chao H, Childers C, Curril I, Dinh H, Doddapaneni H, Dolan A, Dugan S, Friedrich M, Gasperi G, Geib S, Georgakilas G, Gibbs RA, Giers SD, Gomulski LM, González-Guzmán M, Guillem-Amat A, Han Y, Hatzigeorgiou AG, Hernández-Crespo P, Hughes DS, Jones JW, Karagkouni D, Koskinioti P, Lee SL, Malacrida AR, Manni M, Mathiopoulos K, Meccariello A, Munoz-Torres M, Murali SC, Murphy TD, Muzny DM, Oberhofer G, Ortego F, Paraskevopoulou MD, Poelchau M, Qu J, Reczko M, Robertson HM, Rosendale AJ, Rosselot AE, Saccone G, Salvemini M, Savini G, Schreiner P, Scolari F, Siciliano P, Sim SB, Tsiamis G, Ureña E, Vlachos IS, Werren JH, Wimmer EA, Worley KC, Zacharopoulou A, Richards S, Handler AM.

Genome Biol. 2016 Sep 22;17(1):192. doi: 10.1186/s13059-016-1049-2. Erratum in: Genome Biol. 2017 Jan 18;18(1):11.

20.
21.

Size relationships of different body parts in the three dipteran species Drosophila melanogaster, Ceratitis capitata and Musca domestica.

Siomava N, Wimmer EA, Posnien N.

Dev Genes Evol. 2016 Jun;226(3):245-56. doi: 10.1007/s00427-016-0543-6. Epub 2016 Apr 26. Erratum in: Dev Genes Evol. 2016 Jun;226(3):257.

PMID:
27116604
22.

A Single Amino Acid Substitution in Poliovirus Nonstructural Protein 2CATPase Causes Conditional Defects in Encapsidation and Uncoating.

Asare E, Mugavero J, Jiang P, Wimmer E, Paul AV.

J Virol. 2016 Jun 24;90(14):6174-6186. doi: 10.1128/JVI.02877-15. Print 2016 Jul 15.

23.

In vitro and in vivo drug disposition of cilengitide in animals and human.

Dolgos H, Freisleben A, Wimmer E, Scheible H, Krätzer F, Yamagata T, Gallemann D, Fluck M.

Pharmacol Res Perspect. 2016 Mar 17;4(2):e00217. doi: 10.1002/prp2.217. eCollection 2016 Apr.

24.

Cold-Adapted Viral Attenuation (CAVA): Highly Temperature Sensitive Polioviruses as Novel Vaccine Strains for a Next Generation Inactivated Poliovirus Vaccine.

Sanders BP, de Los Rios Oakes I, van Hoek V, Bockstal V, Kamphuis T, Uil TG, Song Y, Cooper G, Crawt LE, Martín J, Zahn R, Lewis J, Wimmer E, Custers JH, Schuitemaker H, Cello J, Edo-Matas D.

PLoS Pathog. 2016 Mar 31;12(3):e1005483. doi: 10.1371/journal.ppat.1005483. eCollection 2016 Mar.

25.

Ab initio parameterization of a charge optimized many-body forcefield for Si-SiO2: Validation and thermal transport in nanostructures.

France-Lanord A, Soukiassian P, Glattli C, Wimmer E.

J Chem Phys. 2016 Mar 14;144(10):104705. doi: 10.1063/1.4943396.

PMID:
26979702
26.

Eradicating polio: A balancing act.

Agol V, Cello J, Chumakov K, Ehrenfeld E, Wimmer E.

Science. 2016 Jan 22;351(6271):348. doi: 10.1126/science.351.6271.348-b. No abstract available.

PMID:
26798005
27.

Evaluation of the attenuation, immunogenicity, and efficacy of a live virus vaccine generated by codon-pair bias de-optimization of the 2009 pandemic H1N1 influenza virus, in ferrets.

Broadbent AJ, Santos CP, Anafu A, Wimmer E, Mueller S, Subbarao K.

Vaccine. 2016 Jan 20;34(4):563-570. doi: 10.1016/j.vaccine.2015.11.054. Epub 2015 Dec 2.

28.

Production of high titer attenuated poliovirus strains on the serum-free PER.C6(®) cell culture platform for the generation of safe and affordable next generation IPV.

Sanders BP, Oakes Ide L, van Hoek V, Liu Y, Marissen W, Minor PD, Wimmer E, Schuitemaker H, Custers JH, Macadam A, Cello J, Edo-Matas D.

Vaccine. 2015 Nov 27;33(48):6611-6. doi: 10.1016/j.vaccine.2015.10.091. Epub 2015 Nov 1.

PMID:
26529068
29.

Serial assessments of microvascular obstruction by contrast-enhanced magnetic resonance predict contractile recovery and clinical outcome after reperfused acute myocardial infarction.

Abegunewardene N, Kreitner KF, Oberholzer K, Vosseler M, Schmidt KH, Wimmer E, Elsäßer A, Gori T, Düber C, Münzel T, Horstick G.

Clin Hemorheol Microcirc. 2015 Sep 25;62(4):345-57. doi: 10.3233/CH-151975.

PMID:
26444606
30.

The iBeetle large-scale RNAi screen reveals gene functions for insect development and physiology.

Schmitt-Engel C, Schultheis D, Schwirz J, Ströhlein N, Troelenberg N, Majumdar U, Dao VA, Grossmann D, Richter T, Tech M, Dönitz J, Gerischer L, Theis M, Schild I, Trauner J, Koniszewski ND, Küster E, Kittelmann S, Hu Y, Lehmann S, Siemanowski J, Ulrich J, Panfilio KA, Schröder R, Morgenstern B, Stanke M, Buchhholz F, Frasch M, Roth S, Wimmer EA, Schoppmeier M, Klingler M, Bucher G.

Nat Commun. 2015 Jul 28;6:7822. doi: 10.1038/ncomms8822.

31.

Synthesis of a new class of iminosugars based on constrained azaspirocyclic scaffolds by way of catalytic C-H amination.

Nocquet PA, Hensienne R, Wencel-Delord J, Wimmer E, Hazelard D, Compain P.

Org Biomol Chem. 2015 Sep 21;13(35):9176-80. doi: 10.1039/c5ob01254f. Epub 2015 Jul 13.

PMID:
26165187
32.

Reply to Simmonds et al.: Codon pair and dinucleotide bias have not been functionally distinguished.

Futcher B, Gorbatsevych O, Shen SH, Stauft CB, Song Y, Wang B, Leatherwood J, Gardin J, Yurovsky A, Mueller S, Wimmer E.

Proc Natl Acad Sci U S A. 2015 Jul 14;112(28):E3635-6. doi: 10.1073/pnas.1507710112. Epub 2015 Jun 12. No abstract available.

33.

Brunenders: a partially attenuated historic poliovirus type I vaccine strain.

Sanders BP, Liu Y, Brandjes A, van Hoek V, de Los Rios Oakes I, Lewis J, Wimmer E, Custers JH, Schuitemaker H, Cello J, Edo-Matas D.

J Gen Virol. 2015 Sep;96(9):2614-22. doi: 10.1099/vir.0.000197. Epub 2015 May 26.

PMID:
26018960
34.

Recoding of the vesicular stomatitis virus L gene by computer-aided design provides a live, attenuated vaccine candidate.

Wang B, Yang C, Tekes G, Mueller S, Paul A, Whelan SP, Wimmer E.

MBio. 2015 Mar 31;6(2). pii: e00237-15. doi: 10.1128/mBio.00237-15.

35.

Large-scale recoding of an arbovirus genome to rebalance its insect versus mammalian preference.

Shen SH, Stauft CB, Gorbatsevych O, Song Y, Ward CB, Yurovsky A, Mueller S, Futcher B, Wimmer E.

Proc Natl Acad Sci U S A. 2015 Apr 14;112(15):4749-54. doi: 10.1073/pnas.1502864112. Epub 2015 Mar 30.

36.

Phosphatidylserine vesicles enable efficient en bloc transmission of enteroviruses.

Chen YH, Du W, Hagemeijer MC, Takvorian PM, Pau C, Cali A, Brantner CA, Stempinski ES, Connelly PS, Ma HC, Jiang P, Wimmer E, Altan-Bonnet G, Altan-Bonnet N.

Cell. 2015 Feb 12;160(4):619-630. doi: 10.1016/j.cell.2015.01.032.

37.

Building technology services that address student needs.

Le Ber JM, Lombardo NT, Wimmer E.

Med Ref Serv Q. 2015;34(1):1-16. doi: 10.1080/02763869.2015.986708.

PMID:
25611437
38.

Initiation of protein-primed picornavirus RNA synthesis.

Paul AV, Wimmer E.

Virus Res. 2015 Aug 3;206:12-26. doi: 10.1016/j.virusres.2014.12.028. Epub 2015 Jan 12. Review.

39.

Tissue-specific transcriptomics, chromosomal localization, and phylogeny of chemosensory and odorant binding proteins from the red flour beetle Tribolium castaneum reveal subgroup specificities for olfaction or more general functions.

Dippel S, Oberhofer G, Kahnt J, Gerischer L, Opitz L, Schachtner J, Stanke M, Schütz S, Wimmer EA, Angeli S.

BMC Genomics. 2014 Dec 18;15:1141. doi: 10.1186/1471-2164-15-1141.

40.

H in α-Zr and in zirconium hydrides: solubility, effect on dimensional changes, and the role of defects.

Christensen M, Wolf W, Freeman C, Wimmer E, Adamson RB, Hallstadius L, Cantonwine PE, Mader EV.

J Phys Condens Matter. 2015 Jan 21;27(2):025402. doi: 10.1088/0953-8984/27/2/025402. Epub 2014 Dec 15.

PMID:
25501106
41.

Perspective on the combined use of an independent transgenic sexing and a multifactorial reproductive sterility system to avoid resistance development against transgenic Sterile Insect Technique approaches.

Eckermann KN, Dippel S, KaramiNejadRanjbar M, Ahmed HM, Curril IM, Wimmer EA.

BMC Genet. 2014;15 Suppl 2:S17. doi: 10.1186/1471-2156-15-S2-S17. Epub 2014 Dec 1. Review.

42.

Polyandry in the medfly - shifts in paternity mediated by sperm stratification and mixing.

Scolari F, Yuval B, Gomulski LM, Schetelig MF, Gabrieli P, Bassetti F, Wimmer EA, Malacrida AR, Gasperi G.

BMC Genet. 2014;15 Suppl 2:S10. doi: 10.1186/1471-2156-15-S2-S10. Epub 2014 Dec 1.

43.

Picornavirus morphogenesis.

Jiang P, Liu Y, Ma HC, Paul AV, Wimmer E.

Microbiol Mol Biol Rev. 2014 Sep;78(3):418-37. doi: 10.1128/MMBR.00012-14. Review.

44.

Inflectional morphology in German hearing-impaired children.

Penke M, Wimmer E, Hennies J, Hess M, Rothweiler M.

Logoped Phoniatr Vocol. 2016;41(1):9-26. doi: 10.3109/14015439.2014.940382. Epub 2014 Sep 1.

PMID:
25175166
45.

Attenuation of human respiratory syncytial virus by genome-scale codon-pair deoptimization.

Le Nouën C, Brock LG, Luongo C, McCarty T, Yang L, Mehedi M, Wimmer E, Mueller S, Collins PL, Buchholz UJ, DiNapoli JM.

Proc Natl Acad Sci U S A. 2014 Sep 9;111(36):13169-74. doi: 10.1073/pnas.1411290111. Epub 2014 Aug 25.

46.

Poliomyelitis in transgenic mice expressing CD155 under the control of the Tage4 promoter after oral and parenteral poliovirus inoculation.

Khan S, Toyoda H, Linehan M, Iwasaki A, Nomoto A, Bernhardt G, Cello J, Wimmer E.

J Gen Virol. 2014 Aug;95(Pt 8):1668-76. doi: 10.1099/vir.0.064535-0. Epub 2014 Apr 30.

47.

Binding of glutathione to enterovirus capsids is essential for virion morphogenesis.

Thibaut HJ, van der Linden L, Jiang P, Thys B, Canela MD, Aguado L, Rombaut B, Wimmer E, Paul A, Pérez-Pérez MJ, van Kuppeveld FJ, Neyts J.

PLoS Pathog. 2014 Apr 10;10(4):e1004039. doi: 10.1371/journal.ppat.1004039. eCollection 2014 Apr.

48.

An interaction between glutathione and the capsid is required for the morphogenesis of C-cluster enteroviruses.

Ma HC, Liu Y, Wang C, Strauss M, Rehage N, Chen YH, Altan-Bonnet N, Hogle J, Wimmer E, Mueller S, Paul AV, Jiang P.

PLoS Pathog. 2014 Apr 10;10(4):e1004052. doi: 10.1371/journal.ppat.1004052. eCollection 2014 Apr.

49.

A C-terminal, cysteine-rich site in poliovirus 2C(ATPase) is required for morphogenesis.

Wang C, Ma HC, Wimmer E, Jiang P, Paul AV.

J Gen Virol. 2014 Jun;95(Pt 6):1255-65. doi: 10.1099/vir.0.062497-0. Epub 2014 Feb 20.

50.

Odoriferous Defensive stink gland transcriptome to identify novel genes necessary for quinone synthesis in the red flour beetle, Tribolium castaneum.

Li J, Lehmann S, Weißbecker B, Ojeda Naharros I, Schütz S, Joop G, Wimmer EA.

PLoS Genet. 2013;9(7):e1003596. doi: 10.1371/journal.pgen.1003596. Epub 2013 Jul 11.

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