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DNA copy-number measurement of genome replication dynamics by high-throughput sequencing: the sort-seq, sync-seq and MFA-seq family.

Batrakou DG, Müller CA, Wilson RHC, Nieduszynski CA.

Nat Protoc. 2020 Mar;15(3):1255-1284. doi: 10.1038/s41596-019-0287-7. Epub 2020 Feb 12.


Effects of the Carrier Phrase on Word Recognition Performances by Younger and Older Listeners Using Two Stimulus Paradigms.

Wilson RH, Sanchez VA.

J Am Acad Audiol. 2020 Jan 22:0. doi: 10.3766/jaaa.19061. [Epub ahead of print]


Dissociation of Cerebral Blood Flow and Femoral Artery Blood Pressure Pulsatility After Cardiac Arrest and Resuscitation in a Rodent Model: Implications for Neurological Recovery.

Crouzet C, Wilson RH, Lee D, Bazrafkan A, Tromberg BJ, Akbari Y, Choi B.

J Am Heart Assoc. 2020 Jan 7;9(1):e012691. doi: 10.1161/JAHA.119.012691. Epub 2020 Jan 4.


A rare case of melorheostosis of the hand in a pediatric patient.

Willacy RA, Clemmons JA, Oyetan O, Khaleel IM, Salib CG, Wilson RH.

J Orthop. 2019 Jun 24;16(5):451-453. doi: 10.1016/j.jor.2019.06.023. eCollection 2019 Sep-Oct.


A conserved asparagine in a ubiquitin-conjugating enzyme positions the substrate for nucleophilic attack.

Jones WM, Davis AG, Wilson RH, Elliott KL, Sumner I.

J Comput Chem. 2019 Aug 15;40(22):1969-1977. doi: 10.1002/jcc.25852. Epub 2019 May 9.


Crystal structure of phosphoribulokinase from Synechococcus sp. strain PCC 6301.

Wilson RH, Hayer-Hartl M, Bracher A.

Acta Crystallogr F Struct Biol Commun. 2019 Apr 1;75(Pt 4):278-289. doi: 10.1107/S2053230X19002693. Epub 2019 Apr 2.


Improved recombinant expression and purification of functional plant Rubisco.

Wilson RH, Thieulin-Pardo G, Hartl FU, Hayer-Hartl M.

FEBS Lett. 2019 Mar;593(6):611-621. doi: 10.1002/1873-3468.13352. Epub 2019 Mar 14.


An extended phase Ib study of epertinib, an orally active reversible dual EGFR/HER2 tyrosine kinase inhibitor, in patients with solid tumours.

Arkenau HT, Italiano A, Mak G, Toulmonde M, Baird RD, Garcia-Corbacho J, Plummer R, Flynn M, Forster M, Wilson RH, Tosi D, Adenis A, Donaldson K, Posner J, Kawabata I, Arimura A, Deva S, Spicer J.

Eur J Cancer. 2018 Nov;103:17-23. doi: 10.1016/j.ejca.2018.07.134. Epub 2018 Sep 6.


Vistusertib (dual m-TORC1/2 inhibitor) in combination with paclitaxel in patients with high-grade serous ovarian and squamous non-small-cell lung cancer.

Basu B, Krebs MG, Sundar R, Wilson RH, Spicer J, Jones R, Brada M, Talbot DC, Steele N, Ingles Garces AH, Brugger W, Harrington EA, Evans J, Hall E, Tovey H, de Oliveira FM, Carreira S, Swales K, Ruddle R, Raynaud FI, Purchase B, Dawes JC, Parmar M, Turner AJ, Tunariu N, Banerjee S, de Bono JS, Banerji U.

Ann Oncol. 2018 Sep 1;29(9):1918-1925. doi: 10.1093/annonc/mdy245.


Musculoskeletal Manifestations of Amyloidosis: A Focused Review.

Nguyen TX, Naqvi A, Thompson TL, Wilson RH.

J Surg Orthop Adv. Spring 2018;27(1):1-5. Review.


Complex Chaperone Dependence of Rubisco Biogenesis.

Wilson RH, Hayer-Hartl M.

Biochemistry. 2018 Jun 12;57(23):3210-3216. doi: 10.1021/acs.biochem.8b00132. Epub 2018 Apr 4. Review.


Rif1 acts through Protein Phosphatase 1 but independent of replication timing to suppress telomere extension in budding yeast.

Kedziora S, Gali VK, Wilson RHC, Clark KRM, Nieduszynski CA, Hiraga SI, Donaldson AD.

Nucleic Acids Res. 2018 May 4;46(8):3993-4003. doi: 10.1093/nar/gky132.


A first-in-human phase I study to determine the maximum tolerated dose of the oral Src/ABL inhibitor AZD0424.

Woodcock VK, Clive S, Wilson RH, Coyle VM, Stratford MRL, Folkes LK, Eastell R, Barton C, Jones P, Kazmi-Stokes S, Turner H, Halford S, Harris AL, Middleton MR.

Br J Cancer. 2018 Mar 20;118(6):770-776. doi: 10.1038/bjc.2017.484. Epub 2018 Feb 13.


Per-Pass Performance Characteristics of Endoscopic Ultrasound-Guided Fine-Needle Aspiration of Malignant Solid Pancreatic Masses in a Large Multicenter Cohort.

Ge PS, Wani S, Watson RR, Sedarat A, Kim S, Marshall C, Wilson RH, Makker J, Mohamadnejad M, Komanduri S, Muthusamy VR.

Pancreas. 2018 Mar;47(3):296-301. doi: 10.1097/MPA.0000000000001003.


High-speed spatial frequency domain imaging of rat cortex detects dynamic optical and physiological properties following cardiac arrest and resuscitation.

Wilson RH, Crouzet C, Torabzadeh M, Bazrafkan A, Farahabadi MH, Jamasian B, Donga D, Alcocer J, Zaher SM, Choi B, Akbari Y, Tromberg BJ.

Neurophotonics. 2017 Oct;4(4):045008. doi: 10.1117/1.NPh.4.4.045008. Epub 2017 Dec 26.


Critical research gaps and recommendations to inform research prioritisation for more effective prevention and improved outcomes in colorectal cancer.

Lawler M, Alsina D, Adams RA, Anderson AS, Brown G, Fearnhead NS, Fenwick SW, Halloran SP, Hochhauser D, Hull MA, Koelzer VH, McNair AGK, Monahan KJ, Näthke I, Norton C, Novelli MR, Steele RJC, Thomas AL, Wilde LM, Wilson RH, Tomlinson I; Bowel Cancer UK Critical Research Gaps in Colorectal Cancer Initiative.

Gut. 2018 Jan;67(1):179-193. doi: 10.1136/gutjnl-2017-315333. Review.


Plant RuBisCo assembly in E. coli with five chloroplast chaperones including BSD2.

Aigner H, Wilson RH, Bracher A, Calisse L, Bhat JY, Hartl FU, Hayer-Hartl M.

Science. 2017 Dec 8;358(6368):1272-1278. doi: 10.1126/science.aap9221.


An improved Escherichia coli screen for Rubisco identifies a protein-protein interface that can enhance CO2-fixation kinetics.

Wilson RH, Martin-Avila E, Conlan C, Whitney SM.

J Biol Chem. 2018 Jan 5;293(1):18-27. doi: 10.1074/jbc.M117.810861. Epub 2017 Oct 6.


Rare cancers: the greatest inequality in cancer research and oncology treatment.

Alvi MA, Wilson RH, Salto-Tellez M.

Br J Cancer. 2017 Oct 24;117(9):1255-1257. doi: 10.1038/bjc.2017.321. Epub 2017 Sep 21. No abstract available.


Molecular dynamics simulations reveal a new role for a conserved active site asparagine in a ubiquitin-conjugating enzyme.

Wilson RH, Zamfir S, Sumner I.

J Mol Graph Model. 2017 Sep;76:403-411. doi: 10.1016/j.jmgm.2017.07.006. Epub 2017 Jul 10.


Transformation-induced changes in the DNA-nuclear matrix interface, revealed by high-throughput analysis of DNA halos.

Wilson RHC, Coverley D.

Sci Rep. 2017 Jul 25;7(1):6475. doi: 10.1038/s41598-017-06459-7.


A Prospective Multicenter Study Evaluating Learning Curves and Competence in Endoscopic Ultrasound and Endoscopic Retrograde Cholangiopancreatography Among Advanced Endoscopy Trainees: The Rapid Assessment of Trainee Endoscopy Skills Study.

Wani S, Keswani R, Hall M, Han S, Ali MA, Brauer B, Carlin L, Chak A, Collins D, Cote GA, Diehl DL, DiMaio CJ, Dries A, El-Hajj I, Ellert S, Fairley K, Faulx A, Fujii-Lau L, Gaddam S, Gan SI, Gaspar JP, Gautamy C, Gordon S, Harris C, Hyder S, Jones R, Kim S, Komanduri S, Law R, Lee L, Mounzer R, Mullady D, Muthusamy VR, Olyaee M, Pfau P, Saligram S, Piraka C, Rastogi A, Rosenkranz L, Rzouq F, Saxena A, Shah RJ, Simon VC, Small A, Sreenarasimhaiah J, Walker A, Wang AY, Watson RR, Wilson RH, Yachimski P, Yang D, Edmundowicz S, Early DS.

Clin Gastroenterol Hepatol. 2017 Nov;15(11):1758-1767.e11. doi: 10.1016/j.cgh.2017.06.012. Epub 2017 Jun 16.


Natural killer-like signature observed post therapy in locally advanced rectal cancer is a determinant of pathological response and improved survival.

Alderdice M, Dunne PD, Cole AJ, O'Reilly PG, McArt DG, Bingham V, Fuchs MA, McQuaid S, Loughrey MB, Murray GI, Samuel LM, Lawler M, Wilson RH, Salto-Tellez M, Coyle VM.

Mod Pathol. 2017 Sep;30(9):1287-1298. doi: 10.1038/modpathol.2017.47. Epub 2017 Jun 16.


Molecular profiling of signet ring cell colorectal cancer provides a strong rationale for genomic targeted and immune checkpoint inhibitor therapies.

Alvi MA, Loughrey MB, Dunne P, McQuaid S, Turkington R, Fuchs MA, McGready C, Bingham V, Pang B, Moore W, Maxwell P, Lawler M, James JA, Murray GI, Wilson RH, Salto-Tellez M.

Br J Cancer. 2017 Jul 11;117(2):203-209. doi: 10.1038/bjc.2017.168. Epub 2017 Jun 8.


A population-level investigation of cancer clinical trials participation in a UK region.

Donnelly CB, Wotherspoon AC, Morris M, Wilson RH, Chen JJ, Cairnduff V, Morgan E, Devlin A, Gavin AT.

Eur J Cancer Prev. 2017 Sep;26 Joining forces for better cancer registration in Europe:S229-S235. doi: 10.1097/CEJ.0000000000000373.


Evaluation of the 2015 AGA guidelines on pancreatic cystic neoplasms in a large surgically confirmed multicenter cohort.

Ge PS, Muthusamy VR, Gaddam S, Jaiyeola DM, Kim S, Sedarat A, Donahue TR, Hosford L, Wilson RH, Grande DP, Keswani RN, Kushnir VM, Mullady D, Edmundowicz SA, Early DS, Komanduri S, Wani S, Watson RR.

Endosc Int Open. 2017 Mar;5(3):E201-E208. doi: 10.1055/s-0042-122010.


A phase I study of intravenous and oral rucaparib in combination with chemotherapy in patients with advanced solid tumours.

Wilson RH, Evans TJ, Middleton MR, Molife LR, Spicer J, Dieras V, Roxburgh P, Giordano H, Jaw-Tsai S, Goble S, Plummer R.

Br J Cancer. 2017 Mar 28;116(7):884-892. doi: 10.1038/bjc.2017.36. Epub 2017 Feb 21.


PCNA dependent cellular activities tolerate dramatic perturbations in PCNA client interactions.

Wilson RH, Biasutto AJ, Wang L, Fischer R, Baple EL, Crosby AH, Mancini EJ, Green CM.

DNA Repair (Amst). 2017 Feb;50:22-35. doi: 10.1016/j.dnarep.2016.12.003. Epub 2016 Dec 31.


Increasing Number of Passes Beyond 4 Does Not Increase Sensitivity of Detection of Pancreatic Malignancy by Endoscopic Ultrasound-Guided Fine-Needle Aspiration.

Mohamadnejad M, Mullady D, Early DS, Collins B, Marshall C, Sams S, Yen R, Rizeq M, Romanas M, Nawaz S, Ulusarac O, Hollander T, Wilson RH, Simon VC, Kushnir V, Amateau SK, Brauer BC, Gaddam S, Azar RR, Komanduri S, Shah R, Das A, Edmundowicz S, Muthusamy VR, Rastogi A, Wani S.

Clin Gastroenterol Hepatol. 2017 Jul;15(7):1071-1078.e2. doi: 10.1016/j.cgh.2016.12.018. Epub 2016 Dec 23.


Cerebral blood flow is decoupled from blood pressure and linked to EEG bursting after resuscitation from cardiac arrest.

Crouzet C, Wilson RH, Bazrafkan A, Farahabadi MH, Lee D, Alcocer J, Tromberg BJ, Choi B, Akbari Y.

Biomed Opt Express. 2016 Oct 20;7(11):4660-4673. eCollection 2016 Nov 1.


Tissue Classification Using Optical Spectroscopy Accurately Differentiates Cancer and Chronic Pancreatitis.

Wilson RH, Chandra M, Scheiman JM, Lee SY, Lee OE, McKenna BJ, Simeone DM, Taylor JM, Mycek MA.

Pancreas. 2017 Feb;46(2):244-251. doi: 10.1097/MPA.0000000000000732.


ADD-ASPIRIN: A phase III, double-blind, placebo controlled, randomised trial assessing the effects of aspirin on disease recurrence and survival after primary therapy in common non-metastatic solid tumours.

Coyle C, Cafferty FH, Rowley S, MacKenzie M, Berkman L, Gupta S, Pramesh CS, Gilbert D, Kynaston H, Cameron D, Wilson RH, Ring A, Langley RE; Add-Aspirin investigators.

Contemp Clin Trials. 2016 Nov;51:56-64. doi: 10.1016/j.cct.2016.10.004. Epub 2016 Oct 21.


A phase I pharmacokinetic and pharmacodynamic study of the oral mitogen-activated protein kinase kinase (MEK) inhibitor, WX-554, in patients with advanced solid tumours.

Jamieson D, Griffin MJ, Sludden J, Drew Y, Cresti N, Swales K, Merriman M, Allen R, Bevan P, Buerkle M, Mala C, Coyle V, Rodgers L, Dean E, Greystoke A, Banerji U, Wilson RH, Evans TR, Anthoney A, Ranson M, Boddy AV, Plummer R.

Eur J Cancer. 2016 Nov;68:1-10. doi: 10.1016/j.ejca.2016.08.026. Epub 2016 Sep 28.


Molecular Subtypes and Personalized Therapy in Metastatic Colorectal Cancer.

Graham DM, Coyle VM, Kennedy RD, Wilson RH.

Curr Colorectal Cancer Rep. 2016;12:141-150. Epub 2016 Apr 18. Review.


Identification of Nanopillars on the Cuticle of the Aquatic Larvae of the Drone Fly (Diptera: Syrphidae).

Hayes MJ, Levine TP, Wilson RH.

J Insect Sci. 2016 Mar 30;16. pii: 36. doi: 10.1093/jisesa/iew019. Print 2016.


Evolving Methanococcoides burtonii archaeal Rubisco for improved photosynthesis and plant growth.

Wilson RH, Alonso H, Whitney SM.

Sci Rep. 2016 Mar 1;6:22284. doi: 10.1038/srep22284.


A Randomized Control Trial: Supplementing Hearing Aid Use with Listening and Communication Enhancement (LACE) Auditory Training.

Saunders GH, Smith SL, Chisolm TH, Frederick MT, McArdle RA, Wilson RH.

Ear Hear. 2016 Jul-Aug;37(4):381-96. doi: 10.1097/AUD.0000000000000283.


Hyperspectral optical tomography of intrinsic signals in the rat cortex.

Konecky SD, Wilson RH, Hagen N, Mazhar A, Tkaczyk TS, Frostig RD, Tromberg BJ.

Neurophotonics. 2015 Oct;2(4):045003. doi: 10.1117/1.NPh.2.4.045003. Epub 2015 Nov 12.


The Nuclear Matrix: Fractionation Techniques and Analysis.

Wilson RH, Hesketh EL, Coverley D.

Cold Spring Harb Protoc. 2016 Jan 4;2016(1):pdb.top074518. doi: 10.1101/pdb.top074518.


Preparation of the Nuclear Matrix for Parallel Microscopy and Biochemical Analyses.

Wilson RH, Hesketh EL, Coverley D.

Cold Spring Harb Protoc. 2016 Jan 4;2016(1):pdb.prot083758. doi: 10.1101/pdb.prot083758.


Optical methods for quantitative and label-free sensing in living human tissues: principles, techniques, and applications.

Wilson RH, Vishwanath K, Mycek MA.

Adv Phys. 2016;1(4):523-543. doi: 10.1080/23746149.2016.1221739. Epub 2016 Sep 1.


Delivering a research-enabled multistakeholder partnership for enhanced patient care at a population level: The Northern Ireland Comprehensive Cancer Program.

Lawler M, Gavin A, Salto-Tellez M, Kennedy RD, Van Schaeybroeck S, Wilson RH, Harkin DP, Grayson M, Boyd RE, Hamilton PW, McArt DG, James J, Robson T, Ladner RD, Prise KM, O'Sullivan JM, Harrison T, Murray L, Johnston PG, Waugh DJ.

Cancer. 2016 Mar 1;122(5):664-73. doi: 10.1002/cncr.29814. Epub 2015 Dec 22. No abstract available.


Distribution Characteristics of Air-Bone Gaps: Evidence of Bias in Manual Audiometry.

Margolis RH, Wilson RH, Popelka GR, Eikelboom RH, Swanepoel de W, Saly GL.

Ear Hear. 2016 Mar-Apr;37(2):177-88. doi: 10.1097/AUD.0000000000000246.


Real-Time Characterization of Diminutive Colorectal Polyp Histology Using Narrow-Band Imaging: Implications for the Resect and Discard Strategy.

Patel SG, Schoenfeld P, Kim HM, Ward EK, Bansal A, Kim Y, Hosford L, Myers A, Foster S, Craft J, Shopinski S, Wilson RH, Ahnen DJ, Rastogi A, Wani S.

Gastroenterology. 2016 Feb;150(2):406-18. doi: 10.1053/j.gastro.2015.10.042. Epub 2015 Oct 30.


Comprehensive molecular pathology analysis of small bowel adenocarcinoma reveals novel targets with potential for clinical utility.

Alvi MA, McArt DG, Kelly P, Fuchs MA, Alderdice M, McCabe CM, Bingham V, McGready C, Tripathi S, Emmert-Streib F, Loughrey MB, McQuaid S, Maxwell P, Hamilton PW, Turkington R, James JA, Wilson RH, Salto-Tellez M.

Oncotarget. 2015 Aug 28;6(25):20863-74.


EphA2 Expression Is a Key Driver of Migration and Invasion and a Poor Prognostic Marker in Colorectal Cancer.

Dunne PD, Dasgupta S, Blayney JK, McArt DG, Redmond KL, Weir JA, Bradley CA, Sasazuki T, Shirasawa S, Wang T, Srivastava S, Ong CW, Arthur K, Salto-Tellez M, Wilson RH, Johnston PG, Van Schaeybroeck S.

Clin Cancer Res. 2016 Jan 1;22(1):230-242. doi: 10.1158/1078-0432.CCR-15-0603. Epub 2015 Aug 17.


Recognition Performance of Interrupted Monosyllabic Words: The Effects of Ten Interruption Locations.

Wilson RH, Hamm HM.

J Am Acad Audiol. 2015 Jul-Aug;26(7):670-7. doi: 10.3766/jaaa.15014.


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