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The Daunting Economics of Therapeutic Genome Editing.

Wilson RC, Carroll D.

CRISPR J. 2019 Oct;2(5):280-284. doi: 10.1089/crispr.2019.0052.


Rats exhibit similar biases in foraging and intertemporal choice tasks.

Kane GA, Bornstein AM, Shenhav A, Wilson RC, Daw ND, Cohen JD.

Elife. 2019 Sep 18;8. pii: e48429. doi: 10.7554/eLife.48429.


Inhibition of the transcriptional kinase CDK7 overcomes therapeutic resistance in HER2-positive breast cancers.

Sun B, Mason S, Wilson RC, Hazard SE, Wang Y, Fang R, Wang Q, Yeh ES, Yang M, Roberts TM, Zhao JJ, Wang Q.

Oncogene. 2019 Aug 28. doi: 10.1038/s41388-019-0953-9. [Epub ahead of print]


ErbB4 promotes malignant peripheral nerve sheath tumor pathogenesis via Ras-independent mechanisms.

Longo JF, Brosius SN, Black L, Worley SH, Wilson RC, Roth KA, Carroll SL.

Cell Commun Signal. 2019 Jul 10;17(1):74. doi: 10.1186/s12964-019-0388-5.


Loss of skin elasticity is associated with pulmonary emphysema, biomarkers of inflammation, and matrix metalloproteinase activity in smokers.

O'Brien ME, Chandra D, Wilson RC, Karoleski CM, Fuhrman CR, Leader JK, Pu J, Zhang Y, Morris A, Nouraie S, Bon J, Urban Z, Sciurba FC.

Respir Res. 2019 Jun 24;20(1):128. doi: 10.1186/s12931-019-1098-7.


Regulation of evidence accumulation by pupil-linked arousal processes.

Keung W, Hagen TA, Wilson RC.

Nat Hum Behav. 2019 Jun;3(6):636-645. doi: 10.1038/s41562-019-0551-4. Epub 2019 Mar 11.


Engineering CRISPR-Cas9 RNA-Protein Complexes for Improved Function and Delivery.

Rouet R, de Oñate L, Li J, Murthy N, Wilson RC.

CRISPR J. 2018 Dec;1(6):367-378. doi: 10.1089/crispr.2018.0037. Review.


Development of a Minimally Invasive Microneedle-Based Sensor for Continuous Monitoring of β-Lactam Antibiotic Concentrations in Vivo.

Gowers SAN, Freeman DME, Rawson TM, Rogers ML, Wilson RC, Holmes AH, Cass AE, O'Hare D.

ACS Sens. 2019 Apr 26;4(4):1072-1080. doi: 10.1021/acssensors.9b00288. Epub 2019 Apr 17.


Liquid array diagnostics: a novel method for rapid detection of microbial communities in single-tube multiplex reactions.

Hiseni P, Wilson RC, Storrø O, Johnsen R, Øien T, Rudi K.

Biotechniques. 2019 Mar;66(3):143-149. doi: 10.2144/btn-2018-0134.


Clinical applications of CRISPR-based genome editing and diagnostics.

Foss DV, Hochstrasser ML, Wilson RC.

Transfusion. 2019 Apr;59(4):1389-1399. doi: 10.1111/trf.15126. Epub 2019 Jan 2. Review.


Prediction in infants and adults: A pupillometry study.

Zhang F, Jaffe-Dax S, Wilson RC, Emberson LL.

Dev Sci. 2019 Jul;22(4):e12780. doi: 10.1111/desc.12780. Epub 2018 Dec 27.


A Novel CLCN5 Mutation Associated With Focal Segmental Glomerulosclerosis and Podocyte Injury.

Solanki AK, Arif E, Morinelli T, Wilson RC, Hardiman G, Deng P, Arthur JM, Velez JC, Nihalani D, Janech MG, Budisavljevic MN.

Kidney Int Rep. 2018 Jun 18;3(6):1443-1453. doi: 10.1016/j.ekir.2018.06.003. eCollection 2018 Nov.


Associations between maternal physical activity in early and late pregnancy and offspring birth size: remote federated individual level meta-analysis from eight cohort studies.

Pastorino S, Bishop T, Crozier SR, Granström C, Kordas K, Küpers LK, O'Brien EC, Polanska K, Sauder KA, Zafarmand MH, Wilson RC, Agyemang C, Burton PR, Cooper C, Corpeleijn E, Dabelea D, Hanke W, Inskip HM, McAuliffe FM, Olsen SF, Vrijkotte TG, Brage S, Kennedy A, O'Gorman D, Scherer P, Wijndaele K, Wareham NJ, Desoye G, Ong KK.

BJOG. 2019 Mar;126(4):459-470. doi: 10.1111/1471-0528.15476. Epub 2018 Oct 22.


Emerging Strategies for Genome Editing in the Brain.

Foss DV, Wilson RC.

Trends Mol Med. 2018 Oct;24(10):822-824. doi: 10.1016/j.molmed.2018.07.008. Epub 2018 Aug 10.


Correction: A Mixture of Delta-Rules Approximation to Bayesian Inference in Change-Point Problems.

Wilson RC, Nassar MR, Tavoni G, Gold JI.

PLoS Comput Biol. 2018 Jun 26;14(6):e1006210. doi: 10.1371/journal.pcbi.1006210. eCollection 2018 Jun.


Tidal breathing parameters measured by structured light plethysmography in children aged 2-12 years recovering from acute asthma/wheeze compared with healthy children.

Hmeidi H, Motamedi-Fakhr S, Chadwick EK, Gilchrist FJ, Lenney W, Iles R, Wilson RC, Alexander J.

Physiol Rep. 2018 Jun;6(12):e13752. doi: 10.14814/phy2.13752.


Receptor-Mediated Delivery of CRISPR-Cas9 Endonuclease for Cell-Type-Specific Gene Editing.

Rouet R, Thuma BA, Roy MD, Lintner NG, Rubitski DM, Finley JE, Wisniewska HM, Mendonsa R, Hirsh A, de Oñate L, Compte Barrón J, McLellan TJ, Bellenger J, Feng X, Varghese A, Chrunyk BA, Borzilleri K, Hesp KD, Zhou K, Ma N, Tu M, Dullea R, McClure KF, Wilson RC, Liras S, Mascitti V, Doudna JA.

J Am Chem Soc. 2018 May 30;140(21):6596-6603. doi: 10.1021/jacs.8b01551. Epub 2018 May 18.


Earthworms are associated with subpopulations of Gammaproteobacteria irrespective of the total soil microbiota composition and stability.

Fjøsne T, Myromslien FD, Wilson RC, Rudi K.

FEMS Microbiol Lett. 2018 May 1;365(9). doi: 10.1093/femsle/fny071.


A centrality measure for cycles and subgraphs II.

Giscard PL, Wilson RC.

Appl Netw Sci. 2018;3(1):9. doi: 10.1007/s41109-018-0064-5. Epub 2018 Jun 8.


Clinical, genetic, and structural basis of apparent mineralocorticoid excess due to 11β-hydroxysteroid dehydrogenase type 2 deficiency.

Yau M, Haider S, Khattab A, Ling C, Mathew M, Zaidi S, Bloch M, Patel M, Ewert S, Abdullah W, Toygar A, Mudryi V, Al Badi M, Alzubdi M, Wilson RC, Al Azkawi HS, Ozdemir HN, Abu-Amer W, Hertecant J, Razzaghy-Azar M, Funder JW, Al Senani A, Sun L, Kim SM, Yuen T, Zaidi M, New MI.

Proc Natl Acad Sci U S A. 2017 Dec 26;114(52):E11248-E11256. doi: 10.1073/pnas.1716621115. Epub 2017 Dec 11.


The Promise and Challenge of In Vivo Delivery for Genome Therapeutics.

Wilson RC, Gilbert LA.

ACS Chem Biol. 2018 Feb 16;13(2):376-382. doi: 10.1021/acschembio.7b00680. Epub 2017 Oct 19. Review.


Synthetic ALSPAC longitudinal datasets for the Big Data VR project.

Avraam D, Wilson RC, Burton P.

Wellcome Open Res. 2017 Aug 30;2:74. doi: 10.12688/wellcomeopenres.12441.1. eCollection 2017.


A causal role for right frontopolar cortex in directed, but not random, exploration.

Zajkowski WK, Kossut M, Wilson RC.

Elife. 2017 Sep 15;6. pii: e27430. doi: 10.7554/eLife.27430.


Increased locus coeruleus tonic activity causes disengagement from a patch-foraging task.

Kane GA, Vazey EM, Wilson RC, Shenhav A, Daw ND, Aston-Jones G, Cohen JD.

Cogn Affect Behav Neurosci. 2017 Dec;17(6):1073-1083. doi: 10.3758/s13415-017-0531-y.


The effect of atomoxetine on random and directed exploration in humans.

Warren CM, Wilson RC, van der Wee NJ, Giltay EJ, van Noorden MS, Cohen JD, Nieuwenhuis S.

PLoS One. 2017 Apr 26;12(4):e0176034. doi: 10.1371/journal.pone.0176034. eCollection 2017.


The ECOUTER methodology for stakeholder engagement in translational research.

Murtagh MJ, Minion JT, Turner A, Wilson RC, Blell M, Ochieng C, Murtagh B, Roberts S, Butters OW, Burton PR.

BMC Med Ethics. 2017 Apr 4;18(1):24. doi: 10.1186/s12910-017-0167-z.


Tidal breathing parameters measured using structured light plethysmography in healthy children and those with asthma before and after bronchodilator.

Hmeidi H, Motamedi-Fakhr S, Chadwick E, Gilchrist FJ, Lenney W, Iles R, Wilson RC, Alexander J.

Physiol Rep. 2017 Mar;5(5). pii: e13168. doi: 10.14814/phy2.13168.


Evaluation of the agreement of tidal breathing parameters measured simultaneously using pneumotachography and structured light plethysmography.

Motamedi-Fakhr S, Iles R, Barney A, de Boer W, Conlon J, Khalid A, Wilson RC.

Physiol Rep. 2017 Feb;5(3). pii: e13124. doi: 10.14814/phy2.13124.


Digital Methodology to implement the ECOUTER engagement process.

Wilson RC, Butters OW, Clark T, Minion J, Turner A, Murtagh MJ.

Version 2. F1000Res. 2016 Jun 9 [revised 2017 Jan 1];5:1307. doi: 10.12688/f1000research.8786.2. eCollection 2016.


Tidal breathing patterns derived from structured light plethysmography in COPD patients compared with healthy subjects.

Motamedi-Fakhr S, Wilson RC, Iles R.

Med Devices (Auckl). 2016 Dec 29;10:1-9. doi: 10.2147/MDER.S119868. eCollection 2017.


Charting the expansion of strategic exploratory behavior during adolescence.

Somerville LH, Sasse SF, Garrad MC, Drysdale AT, Abi Akar N, Insel C, Wilson RC.

J Exp Psychol Gen. 2017 Feb;146(2):155-164. doi: 10.1037/xge0000250. Epub 2016 Dec 15.


Human Orbitofrontal Cortex Represents a Cognitive Map of State Space.

Schuck NW, Cai MB, Wilson RC, Niv Y.

Neuron. 2016 Sep 21;91(6):1402-1412. doi: 10.1016/j.neuron.2016.08.019.


Complementary feature selection from alternative splicing events and gene expression for phenotype prediction.

Labuzzetta CJ, Antonio ML, Watson PM, Wilson RC, Laboissonniere LA, Trimarchi JM, Genc B, Ozdinler PH, Watson DK, Anderson PE.

Bioinformatics. 2016 Sep 1;32(17):i421-i429. doi: 10.1093/bioinformatics/btw430.


A novel mutation in HSD11B2 causes apparent mineralocorticoid excess in an Omani kindred.

Yau M, Azkawi HS, Haider S, Khattab A, Badi MA, Abdullah W, Senani AA, Wilson RC, Yuen T, Zaidi M, New MI.

Ann N Y Acad Sci. 2016 Jul;1376(1):65-71. doi: 10.1111/nyas.13162. Epub 2016 Aug 15.


Systems analysis of the prostate transcriptome in African-American men compared with European-American men.

Hardiman G, Savage SJ, Hazard ES, Wilson RC, Courtney SM, Smith MT, Hollis BW, Halbert CH, Gattoni-Celli S.

Pharmacogenomics. 2016 Jul;17(10):1129-1143. Epub 2016 Jun 30.


Measuring changes in chest wall motion after lung resection using structured light plethysmography: a feasibility study.

Elshafie G, Kumar P, Motamedi-Fakhr S, Iles R, Wilson RC, Naidu B.

Interact Cardiovasc Thorac Surg. 2016 Oct;23(4):544-7. doi: 10.1093/icvts/ivw185. Epub 2016 Jun 16.


Catecholamine-Mediated Increases in Gain Enhance the Precision of Cortical Representations.

Warren CM, Eldar E, van den Brink RL, Tona KD, van der Wee NJ, Giltay EJ, van Noorden MS, Bosch JA, Wilson RC, Cohen JD, Nieuwenhuis S.

J Neurosci. 2016 May 25;36(21):5699-708. doi: 10.1523/JNEUROSCI.3475-15.2016.


Functional oncogene signatures guide rationally designed combination therapies to synergistically induce breast cancer cell death.

Guest ST, Kratche ZR, Irish JC, Wilson RC, Haddad R, Gray JW, Garrett-Mayer E, Ethier SP.

Oncotarget. 2016 Jun 14;7(24):36138-36153. doi: 10.18632/oncotarget.9147.


Molecular genetic analysis in 93 patients and 193 family members with classical congenital adrenal hyperplasia due to 21-hydroxylase deficiency in Croatia.

Dumic KK, Grubic Z, Yuen T, Wilson RC, Kusec V, Barisic I, Stingl K, Sansovic I, Skrabic V, Dumic M, New MI.

J Steroid Biochem Mol Biol. 2017 Jan;165(Pt A):51-56. doi: 10.1016/j.jsbmb.2016.03.035. Epub 2016 Mar 31.


A bacterial Argonaute with noncanonical guide RNA specificity.

Kaya E, Doxzen KW, Knoll KR, Wilson RC, Strutt SC, Kranzusch PJ, Doudna JA.

Proc Natl Acad Sci U S A. 2016 Apr 12;113(15):4057-62. doi: 10.1073/pnas.1524385113. Epub 2016 Mar 30.


Multivariate models from RNA-Seq SNVs yield candidate molecular targets for biomarker discovery: SNV-DA.

Paul MR, Levitt NP, Moore DE, Watson PM, Wilson RC, Denlinger CE, Watson DK, Anderson PE.

BMC Genomics. 2016 Mar 31;17:263. doi: 10.1186/s12864-016-2542-4.


Amplification of WHSC1L1 regulates expression and estrogen-independent activation of ERα in SUM-44 breast cancer cells and is associated with ERα over-expression in breast cancer.

Irish JC, Mills JN, Turner-Ivey B, Wilson RC, Guest ST, Rutkovsky A, Dombkowski A, Kappler CS, Hardiman G, Ethier SP.

Mol Oncol. 2016 Jun;10(6):850-65. doi: 10.1016/j.molonc.2016.02.003. Epub 2016 Feb 27.


Bayesian Modeling of the Dynamics of Phase Modulations and their Application to Auditory Event Related Potentials at Different Loudness Scales.

Mortezapouraghdam Z, Wilson RC, Schwabe L, Strauss DJ.

Front Comput Neurosci. 2016 Jan 28;10:2. doi: 10.3389/fncom.2016.00002. eCollection 2016.


Integrative "omic" analysis reveals distinctive cold responses in leaves and roots of strawberry, Fragaria × ananassa 'Korona'.

Koehler G, Rohloff J, Wilson RC, Kopka J, Erban A, Winge P, Bones AM, Davik J, Alsheikh MK, Randall SK.

Front Plant Sci. 2015 Oct 15;6:826. doi: 10.3389/fpls.2015.00826. eCollection 2015.


Spherical and Hyperbolic Embeddings of Data.

Wilson RC, Hancock ER, Pekalska E, Duin RP.

IEEE Trans Pattern Anal Mach Intell. 2014 Nov;36(11):2255-69. doi: 10.1109/TPAMI.2014.2316836.


Generative Graph Prototypes from Information Theory.

Han L, Wilson RC, Hancock ER.

IEEE Trans Pattern Anal Mach Intell. 2015 Oct;37(10):2013-27. doi: 10.1109/TPAMI.2015.2400451.


Is Model Fitting Necessary for Model-Based fMRI?

Wilson RC, Niv Y.

PLoS Comput Biol. 2015 Jun 18;11(6):e1004237. doi: 10.1371/journal.pcbi.1004237. eCollection 2015 Jun.


Reinforcement learning in multidimensional environments relies on attention mechanisms.

Niv Y, Daniel R, Geana A, Gershman SJ, Leong YC, Radulescu A, Wilson RC.

J Neurosci. 2015 May 27;35(21):8145-57. doi: 10.1523/JNEUROSCI.2978-14.2015.


Dicer-TRBP complex formation ensures accurate mammalian microRNA biogenesis.

Wilson RC, Tambe A, Kidwell MA, Noland CL, Schneider CP, Doudna JA.

Mol Cell. 2015 Feb 5;57(3):397-407. doi: 10.1016/j.molcel.2014.11.030. Epub 2014 Dec 31.


Oncogenic signaling in amphiregulin and EGFR-expressing PTEN-null human breast cancer.

Kappler CS, Guest ST, Irish JC, Garrett-Mayer E, Kratche Z, Wilson RC, Ethier SP.

Mol Oncol. 2015 Feb;9(2):527-43. doi: 10.1016/j.molonc.2014.10.006. Epub 2014 Oct 23.

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